-
1.发明公开METHOD FOR GENERATING SPLIT, NON-TRANSFERABLE GENES THAT ARE ABLE TO EXPRESS AN ACTIVE PROTEIN PRODUCT 有权用于生产，这使是一个积极的蛋白产物表达分离的非传染性基因
公开(公告)号：EP1183346A1
公开(公告)日：2002-03-06
申请号：EP00932712.3
申请日：2000-05-23
发明人： XU, Ming-Qun , EVANS, Thomas, C. , PRADHAN, Sriharsa , COMB, Donald, G. , PAULUS, Henry , SUN, Luo , CHEN, Lixin , GHOSH, Inca
CPC分类号： C12N9/1029 , C07K14/43595 , C07K2319/00 , C07K2319/055 , C07K2319/06 , C07K2319/08 , C07K2319/09 , C07K2319/32 , C07K2319/75 , C07K2319/92 , C12N9/1092 , C12N9/1252 , C12N9/88 , C12N15/10 , C12N15/62 , C12N15/8214 , C12N15/8216 , C12N15/8241 , C12N15/8242 , C12N15/8257 , C12N15/8275 , C12N15/8278 , C12P21/02
摘要： A new type of transgene system is disclosed which allows efficient protein expression in a target host such as a plant, but avoids the undesirable result of the migration of the transgene into related host systems and/or to the environment via the pollen. The methods described herein may also be applied to the expression of virtually any protein of interest (e.g. a toxic protein) in eukaryotic (yeast, insect, mammalian cells, etc.) and prokaryotic (E. coli, etc.) organisms.
-
2.发明授权METHOD FOR GENERATING SPLIT, NON-TRANSFERABLE GENES THAT ARE ABLE TO EXPRESS AN ACTIVE PROTEIN PRODUCT 有权用于生产，这使是一个积极的蛋白产物表达分离的非传染性基因
公开(公告)号：EP1183346B1
公开(公告)日：2007-10-31
申请号：EP00932712.3
申请日：2000-05-23
发明人： XU, Ming-Qun , EVANS, Thomas, C. , PRADHAN, Sriharsa , COMB, Donald, G. , PAULUS, Henry , SUN, Luo , CHEN, Lixin , GHOSH, Inca
CPC分类号： C12N9/1029 , C07K14/43595 , C07K2319/00 , C07K2319/055 , C07K2319/06 , C07K2319/08 , C07K2319/09 , C07K2319/32 , C07K2319/75 , C07K2319/92 , C12N9/1092 , C12N9/1252 , C12N9/88 , C12N15/10 , C12N15/62 , C12N15/8214 , C12N15/8216 , C12N15/8241 , C12N15/8242 , C12N15/8257 , C12N15/8275 , C12N15/8278 , C12P21/02
摘要： A new type of transgene system is disclosed which allows efficient protein expression in a target host such as a plant, but avoids the undesirable result of the migration of the transgene into related host systems and/or to the environment via the pollen. The methods described herein may also be applied to the expression of virtually any protein of interest (e.g. a toxic protein) in eukaryotic (yeast, insect, mammalian cells, etc.) and prokaryotic (E. coli, etc.) organisms.
-
公开(公告)号：EP4219746A3
公开(公告)日：2023-10-18
申请号：EP23156800.7
申请日：2017-08-31
IPC分类号： C12Q1/68
摘要： Provided herein, among other things, are various compositions and methods for analyzing chromatin. In some embodiments, the composition may comprise a mixture of a nicking enzyme, four dNTPs, at least one labeled dNTP and, optionally, a polymerase. In some embodiments, this method may comprise: obtaining a sample comprising chromatin, reacting the sample with the composition to selectively label the open chromatin in the sample, and analyzing the labeled sample.
-
公开(公告)号：EP4110944A1
公开(公告)日：2023-01-04
申请号：EP21743314.3
申请日：2021-06-08
发明人： PRADHAN, Sriharsa , CHIN, Hang Gyeong , FEEHERY, George R. , XU, Shuang-Yong , UDAYAKUMARAN NAIR SUNITHA KUMARY, Vishnu , BEAULIEU, Julie , ESTEVE, Pierre Olivier
IPC分类号： C12Q1/6841 , C12Q1/6869
-
公开(公告)号：EP4219746A2
公开(公告)日：2023-08-02
申请号：EP23156800.7
申请日：2017-08-31
IPC分类号： C12Q1/68
摘要： Provided herein, among other things, are various compositions and methods for analyzing chromatin. In some embodiments, the composition may comprise a mixture of a nicking enzyme, four dNTPs, at least one labeled dNTP and, optionally, a polymerase. In some embodiments, this method may comprise: obtaining a sample comprising chromatin, reacting the sample with the composition to selectively label the open chromatin in the sample, and analyzing the labeled sample.
-
-
公开(公告)号：EP3885448A1
公开(公告)日：2021-09-29
申请号：EP21174494.1
申请日：2017-08-31
IPC分类号： C12Q1/68
摘要： Provided herein, among other things, are various compositions and methods for analyzing chromatin. In some embodiments, the composition may comprise a mixture of a nicking enzyme, four dNTPs, at least one labeled dNTP and, optionally, a polymerase. In some embodiments, this method may comprise: obtaining a sample comprising chromatin, reacting the sample with the composition to selectively label the open chromatin in the sample, and analyzing the labeled sample.
-
8.发明授权DETECTION AND QUANTIFICATION OF HYDROXYMETHYLATED NUCLEOTIDES IN A POLYNUCLEOTIDE PREPARATION 有权多核苷酸制剂中羟甲基化核苷酸的检测和定量
公开(公告)号：EP2470675B1
公开(公告)日：2016-03-30
申请号：EP10812579.0
申请日：2010-08-25
发明人： BITINAITE, Jurate , VAISVILA, Romualdas , PRADHAN, Sriharsa , ZHENG, Yu , ROBERTS, Richard, J. , CHIN, Hang-gyeong , COHEN-KARNI, Devora , NOREN, Christopher , RALEIGH, Elisabeth, A. , WILSON, Geoffrey G.
IPC分类号： C12Q1/68
CPC分类号： C12Q1/6883 , C12Q1/6827 , C12Q2600/154 , C12Q2521/331 , C12Q2525/191 , C12Q2531/113
-
9.发明公开DETECTION AND QUANTIFICATION OF HYDROXYMETHYLATED NUCLEOTIDES IN A POLYNUCLEOTIDE PREPARATION 有权多核苷酸制剂中羟甲基化核苷酸的检测和定量
公开(公告)号：EP2470675A1
公开(公告)日：2012-07-04
申请号：EP10812579.0
申请日：2010-08-25
发明人： BITINAITE, Jurate , VAISVILA, Romualdas , PRADHAN, Sriharsa , ZHENG, Yu , ROBERTS, Richard, J. , CHIN, Hang-gyeong , COHEN-KARNI, Devora , NOREN, Christopher , RALEIGH, Elisabeth, A. , WILSON, Geoffrey G.
IPC分类号： C12Q1/68
CPC分类号： C12Q1/6883 , C12Q1/6827 , C12Q2600/154 , C12Q2521/331 , C12Q2525/191 , C12Q2531/113
摘要： Methods and compositions are described for detecting hydroxymethylated nucleotides (hmNs) in a polynucleotide preparation with a view to mapping the location of hmNs in a genome, quantifying the occurrence of hmNs at selected loci and correlating the occurrence of hmNs with gene expression and phenotypic traits. Embodiments describe the use of modifying enzymes together with site-specific endonucleases to detect the hmNs.
摘要翻译： 描述了用于检测多核苷酸制备物中的羟甲基化核苷酸（hmNs）的方法和组合物，以便映射hmNs在基因组中的位置，定量选择的基因座处hmNs的发生并将hmNs的发生与基因表达和表型性状相关联。 实施方案描述了将酶与位点特异性核酸内切酶一起修饰以检测hmNs的用途。
-
10.发明公开ORGANELLAR TARGETING OF RNA AND ITS USE IN THE INTERRUPTION OF ENVIRONMENTAL GENE FLOW 审中-公开RNA和使用中的中断基因流动环境中的器官ELLEN TARGETING THEREOF
公开(公告)号：EP1558724A2
公开(公告)日：2005-08-03
申请号：EP03776626.8
申请日：2003-10-31
CPC分类号： C12N15/8265 , C12N15/8214
摘要： Methods and compositions are provided which relate to translocating an RNA corresponding to a gene or gene fragment into the chloroplast by means of a chloroplast localization sequence. Additionally plant cells are described in which the chloroplast contains a ribozyme fused at one end to an RNA encoding a fragment of the protein such that the ribozyme can trans-splice the translocated fusion RNA to the RNA encoding the gene fragment to form an intact mRNA encoding a functional protein.
-
-
-
-
-
-
-
-
-
搜索结果
10 条记录 (耗时 0.018 秒)
