公开(公告)号：EP2537019A4

公开(公告)日：2014-03-12

申请号：EP11745384

申请日：2011-02-18

Applicant: PACIFIC BIOSCIENCES CALIFORNIA

Inventor： MCCAFFREY NATHANIEL JOSEPH ,  TURNER STEPHEN ,  SAXENA RAVI ,  HELGESEN SCOTT EDWARD

IPC: G01N21/64 ,  B82Y20/00 ,  G01N21/03 ,  G01N21/05

CPC classification number: C12Q1/6874 ,  B01L3/502707 ,  B01L3/502715 ,  B01L2300/0654 ,  B01L2300/0663 ,  B01L2300/0816 ,  B01L2300/168 ,  B82Y20/00 ,  C12Q1/6825 ,  C12Q1/6869 ,  G01N21/03 ,  G01N21/0303 ,  G01N21/05 ,  G01N21/64 ,  G01N21/6428 ,  G01N21/645 ,  G01N21/6452 ,  G01N21/6454 ,  G01N21/6456 ,  G01N21/648 ,  G01N21/75 ,  G01N21/77 ,  G01N33/54373 ,  G01N2021/0346 ,  G01N2021/6434 ,  G01N2021/6439 ,  G01N2021/6441 ,  G01N2021/6463 ,  G01N2021/757 ,  G01N2021/7786 ,  G01N2201/067 ,  G01N2201/068 ,  G01N2201/08 ,  G02B6/1226 ,  Y10T436/143333

Abstract: A system for measuring analytical reactions comprising a socket (51, 57) which is suitable for holding an optode array chip (40).The socket comprises electrical contacts that mate with electrical contacts on a chip when such a chip is inserted into the socket. The socket furthermore permits fluid from a fluidics system (33) and illumination from an illumination system (53) to be for delivered to a chip when such a chip is inserted into the socket. The socket may be of the clam shell type.

Abstract translation: 一种用于测量分析反应的系统，包括适于保持光栅阵列芯片（40）的插座（51,57）。当这种芯片插入插座时，该插座包括与芯片上的电触点相配合的电触点。 插座还允许来自流体系统（33）的流体和来自照明系统（53）的照明在将芯片插入插座时被输送到芯片。 插座可以是蛤壳型。

公开(公告)号：EP3186617A4

公开(公告)日：2018-04-25

申请号：EP15835461

申请日：2015-08-26

Applicant: PACIFIC BIOSCIENCES CALIFORNIA INC

Inventor： GROT ANNETTE ,  SAXENA RAVI ,  LUNDQUIST PAUL

IPC: G01N21/64 ,  G01N21/77 ,  G02B5/18 ,  G02B5/20 ,  G02B5/28 ,  G02B6/12 ,  G02B6/132 ,  G02B6/136 ,  G02B27/42 ,  H01L27/146

CPC classification number: G01N21/6454 ,  G01N21/6428 ,  G01N21/648 ,  G01N21/7703 ,  G01N21/78 ,  G01N2021/6439 ,  G01N2021/6478 ,  G01N2021/7756 ,  G01N2021/7786 ,  G01N2201/068 ,  G01N2201/0873 ,  G02B5/1895 ,  G02B5/201 ,  G02B5/285 ,  G02B6/132 ,  G02B6/136 ,  G02B27/4238 ,  G02B27/4244 ,  G02B2006/12102 ,  G02B2006/12109 ,  H01L27/14621 ,  H01L27/14627 ,  H01L27/14685

Abstract: Arrays of integrated analytical devices and their methods for production are provided. The arrays are useful in the analysis of highly multiplexed optical reactions in large numbers at high densities, including biochemical reactions, such as nucleic acid sequencing reactions. The devices allow the highly sensitive discrimination of optical signals using features such as spectra, amplitude, and time resolution, or combinations thereof. The devices include an integrated diffractive beam shaping element that provides for the spatial separation of light emitted from the optical reactions.

公开(公告)号：EP2362947A4

公开(公告)日：2012-10-24

申请号：EP09818087

申请日：2009-09-25

Applicant: PACIFIC BIOSCIENCES CALIFORNIA

Inventor： ZACCARIN DENIS ,  LUNDQUIST PAUL ,  ZHAO PEIQIAN ,  ZHONG FRANK ,  TURNER STEPHEN ,  HUANG YANQIAO ,  MONADGEMI PEZHMAN ,  SAXENA RAVI ,  GROT ANNETTE ,  RULISON AARON

IPC: G02B6/12 ,  G01N21/00

CPC classification number: G01N21/6452 ,  B05D1/005 ,  C23C16/50 ,  G01N21/253 ,  G02B6/12002 ,  G02B6/131 ,  G02B6/132 ,  G02B6/136 ,  G02B2006/12035 ,  G02B2006/12061 ,  G02B2006/12104 ,  G02B2006/12164 ,  G02B2006/12197