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1.发明公开Lipid Film Structure Containing a Polyoxyalkylene Chain-Containing Lipid Derivative. 有权Lipidfilmstruktur enthaltend ein Polyoxenylenkettenhaltiges Lipidderivat
公开(公告)号：EP2382996A2
公开(公告)日：2011-11-02
申请号：EP11172230.2
申请日：2006-02-17
发明人： KIWADA, Hiroshi , ISHIDA, Tatsuhiro , ITO, Chika , KUBO, Kazuhiro , SAKANOUE, Kenji , KIKUCHI, Hiroshi
CPC分类号： C07K7/06 , A61K9/1271 , A61K47/60 , A61K47/62 , C07K5/0806 , C07K5/1008
摘要： A polyoxyalkylene chain-containing lipid derivative, which is represented by the following formula (1):
wherein L, Y, W, X 1 , X 2 , X 3 , OA, Z, m1, m2, m3, n1, n2 and n3 are as defined in the specification.摘要翻译： 由下式（1）表示的含有聚氧化烯链的脂质衍生物：其中L，Y，W，X 1，X 2，X 3，OA，Z，m1，m2，m3，n1，n2和n3 如本说明书中所定义。
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2.发明授权Lipid film structure containing a polyoxyalkylene chain-containing lipid derivative. 有权脂质膜结构，其包括脂质衍生物Polyoxyalkylenkettenhaltiges
公开(公告)号：EP2382996B1
公开(公告)日：2015-01-14
申请号：EP11172230.2
申请日：2006-02-17
发明人： KIWADA, Hiroshi , ISHIDA, Tatsuhiro , ITO, Chika , KUBO, Kazuhiro , SAKANOUE, Kenji , KIKUCHI, Hiroshi
CPC分类号： C07K7/06 , A61K9/1271 , A61K47/60 , A61K47/62 , C07K5/0806 , C07K5/1008
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3.发明公开POLYOXYALKYLENE CHAIN-CONTAINING LIPID DERIVATIVE AND LIPID FILM STRUCTURE CONTAINING SUCH DERIVATIVE 审中-公开含聚氧化烯脂质衍生物，此类衍生物含有脂质膜结构
公开(公告)号：EP1854807A1
公开(公告)日：2007-11-14
申请号：EP06714495.6
申请日：2006-02-17
发明人： KIWADA, Hiroshi, c/o THE UNIVERSITY OF TOKUSHIMA , ISHIDA, Tatsuhiro, c/o THE UNIV. OF TOKUSHIMA , ITO, Chika , KUBO, Kazuhiro , SAKANOUE, Kenji , KIKUCHI, Hiroshi
CPC分类号： C07K7/06 , A61K9/1271 , A61K47/60 , A61K47/62 , C07K5/0806 , C07K5/1008
摘要： A polyoxyalkylene chain-containing lipid derivative, which is represented by the following formula (1):
wherein L, Y, W, X 1 , X 2 , X 3 , OA, Z, m1, m2, m3, n1, n2 and n3 are as defined in the specification.摘要翻译： 含聚氧化烯链的脂质衍生物，其是由下式（1）表示：其中L，Y，W，X 1，X 2，X 3，OA，Z，M1，M2，M3中，n1，n2和n3 如说明书中所定义。
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4.发明公开Lipid Film Structure Containing a Polyoxyalkylene Chain-Containing Lipid Derivative. 有权脂质膜结构，其包括脂质衍生物Polyoxyalkylenkettenhaltiges
公开(公告)号：EP2382996A3
公开(公告)日：2012-03-28
申请号：EP11172230.2
申请日：2006-02-17
发明人： KIWADA, Hiroshi , ISHIDA, Tatsuhiro , ITO, Chika , KUBO, Kazuhiro , SAKANOUE, Kenji , KIKUCHI, Hiroshi
CPC分类号： C07K7/06 , A61K9/1271 , A61K47/60 , A61K47/62 , C07K5/0806 , C07K5/1008
摘要： A polyoxyalkylene chain-containing lipid derivative, which is represented by the following formula (1):
wherein L, Y, W, X 1 , X 2 , X 3 , OA, Z, m1, m2, m3, n1, n2 and n3 are as defined in the specification.-
公开(公告)号：EP1498420B1
公开(公告)日：2017-02-01
申请号：EP03715589.2
申请日：2003-03-28
申请人： NOF CORPORATION
发明人： ITOH, Chika , KUBO, Kazuhiro , OHHASHI, Syunsuke , YASUKOHCHI, Tohru , KIKUCHI, Hiroshi, DAIICHI PHARMACEUTICAL CO., LTD , SUZUKI, Norio, DAIICHI PHARMACEUTICAL CO., LTD. , TAKAHASHI, Miho, DAIICHI PHARMACEUTICAL CO., LTD. , YAMAUCHI, Hitoshi, DAIICHI PHARMACEUTICAL CO, LTD
IPC分类号： C07F9/09 , C08G65/335 , A61K9/127 , A61K47/24 , A61P35/00
CPC分类号： A61K47/24 , A61K8/14 , A61K8/553 , A61K8/556 , A61K8/86 , A61K9/1271 , A61Q19/00 , C07F9/10 , C08G65/2609 , C08G65/3353
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公开(公告)号：EP2868653B1
公开(公告)日：2016-11-23
申请号：EP13813591.8
申请日：2013-06-21
申请人： NOF Corporation
发明人： KUBO, Kazuhiro , TANGE, Kota , OHTA, Masaki
IPC分类号： C07C213/06 , C07C217/28 , C07D295/08 , C07B61/00
CPC分类号： C07C213/06 , C07D295/08 , C07C217/28
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公开(公告)号：EP1591447A1
公开(公告)日：2005-11-02
申请号：EP03778894.0
申请日：2003-12-12
发明人： KUBO, Kazuhiro , ITOH, Chika , OHHASHI, Syunsuke , YASUKOHCHI, Tohru , OHKAWA, Yusuke , KIKUCHI, Hiroshi DAIICHI PHARMACEUTICAL CO., LTD. , SUZUKI, Norio DAIICHI PHARMACEUTICAL CO., LTD. , TAKAHASHI, Miho DAIICHI PHARMACEUTICAL CO., LTD. , YAMAUCHI, Hitoshi DAIICHI PHARMACEUTICAL CO., LTD
CPC分类号： A61K9/127 , A61K8/14 , A61K8/553 , A61K9/0014 , A61K9/1273 , A61K47/24 , A61Q19/00 , C07F9/10 , C08G65/2609 , C08G65/3353 , C08G2650/34
摘要： A phospholipid derivative represented by the following formula (1):
wherein [PG]k represents a residue of polyglycerin having a polymerization degree of k, wherein k is 2 to 50, R 1 CO and R 2 CO independently represent an acyl group having 8 to 22 carbon atoms, symbol "a" independently represents an integer of 0 to 5, symbol "b" independently represents 0 or 1, M represents hydrogen atom, an alkali metal atom, an ammonium, or an organic ammonium, and k1, k2, and k3 represent numbers satisfying the following conditions: 1 ≦ k1 ≦ (k+2)/2, 0 ≦ k2, and k1 + k2 + k3 = k + 2. The phospholipid derivative is highly safe for living bodies and can be suitably utilized in drug delivery systems such as liposome, and the like.-
公开(公告)号：EP3184506B1
公开(公告)日：2019-07-24
申请号：EP15833801.2
申请日：2015-08-07
发明人： SASAKI, Shota , OTA, Masaki , KUBO, Kazuhiro , HARASHIMA, Hideyoshi , AKITA, Hidetaka , HATAKEYAMA, Hiroto , NOGUCHI, Yuki , TANGE, Kota , NAKAI, Yuta , SHIMIZU, Nayuta
IPC分类号： C07C229/12 , A61K31/7088 , A61K47/18 , A61K48/00 , A61P43/00
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公开(公告)号：EP2500348B1
公开(公告)日：2017-08-23
申请号：EP10830032.8
申请日：2010-11-12
发明人： ARAI, Masaya , KUBO, Kazuhiro , YOKOYAMA, Shoichi , KONO, Kenji
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10.发明授权CATIONIC LIPID HAVING IMPROVED INTRACELLULAR KINETICS 有权KATIONISCHES LIPID MIT VERBESSERTERINTRAZELLULÄRERKINETIK
公开(公告)号：EP2781507B1
公开(公告)日：2017-03-22
申请号：EP12850198.8
申请日：2012-11-09
发明人： TANGE, Kota , ARAI, Masaya , KUBO, Kazuhiro , AKITA, Hidetaka , HARASHIMA, Hideyoshi , HATAKEYAMA, Hiroto , ISHIBA, Ryohei , UKAWA, Masami , TANAKA, Hiroki
IPC分类号： C07C323/25 , A61K47/20 , A61K47/44 , A61K48/00
CPC分类号： C12N15/88 , A61K9/0019 , A61K9/1271 , A61K9/1272 , A61K47/20 , A61K47/22 , C07C323/25 , C07C2601/16 , C07D311/72
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