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16 条记录 (耗时 0.009 秒)

    APPARATUS AND METHOD FOR MAKING A SEALABLE CONNECTION TO A CHROMATOGRAPHY CARTRIDGE
    2.
    发明公开
    APPARATUS AND METHOD FOR MAKING A SEALABLE CONNECTION TO A CHROMATOGRAPHY CARTRIDGE 审中-公开
    系统及其制造方法连接到可密封的CHROMATOGRAPHIEPATRONE

    公开(公告)号：EP1044046A4

    公开(公告)日：2008-05-28

    申请号：EP98957759

    申请日：1998-11-10

    申请人： BIOTAGE INC

    发明人： LEAVESLEY PETER J ,  VAN DAVELAAR PETER C ,  LOCKMAN ROBERT D

    IPC分类号： G01N30/60 ,  B01D15/00 ,  B01D15/08 ,  G01N30/46 ,  G01N30/52

    CPC分类号： G01N30/6091 ,  G01N30/461 ,  G01N30/6017 ,  G01N30/6021 ,  G01N30/6026 ,  G01N30/603 ,  G01N30/6039 ,  G01N30/6069 ,  G01N2030/522

    摘要： An apparatus and method for sealing cartridges (24) used in liquid chromatography. Such cartridges (24) are commonly filled with media beds (28) that are bounded axially by porous plates (30). The invention involves one or two sealing heads (2). Each sealing head (2) includes two slidably connected head pieces (4, 18) and an elastomeric sealing member (22). The head pieces (4, 18) and the elastomeric sealing member (22) are sized to slide easily into an open end of a cartridge (24) when the elastomeric sealing member (22) is uncompressed. After insertion, relative movement of the head pieces (4, 18) compresses the elastomeric sealing member (22) and causes the elastomeric sealing member (22) to expand laterally so that it forms a seal against the cartridge (24), when the sealing head (2) is pressed against the media (28) or porous plate (30). An alternate sealing head comprises a plurality of head pieces and a plurality of annular sealing members. One of the head pieces contains a body portion on which the other head pieces and the sealing members are slidably mounted.

    LIQUID CHROMATOGRAPHY COLUMN
    3.
    发明公开
    LIQUID CHROMATOGRAPHY COLUMN 审中-公开
    FLÜSSIGECHROMATOGRAPHIESÄULE

    公开(公告)号：EP1044047A4

    公开(公告)日：2008-04-16

    申请号：EP98957835

    申请日：1998-11-12

    申请人： BIOTAGE INC

    发明人： GREEN JEFFREY R ,  KASTER JEFFREY A ,  LANCASTER VICTOR R ,  LEAVESLEY PETER J ,  MCNEIL GARY L ,  RANSOHOFF THOMAS C ,  VAN DAVELAAR PETER C

    IPC分类号： B01D15/08 ,  B01D15/20 ,  B01D15/22 ,  G01N30/52 ,  G01N30/60 ,  G01N30/88

    CPC分类号： G01N30/6091 ,  B01D15/20 ,  B01D15/22 ,  G01N30/60 ,  G01N30/6004 ,  G01N30/6017 ,  G01N30/6047 ,  G01N2030/522 ,  G01N2030/8881

    摘要： A chromatography cartridge assembly includes a cartridge and first (40) and second end caps (42). A wall of the cartridge (22) defines a chamber (82) for containing chromatography media. The end caps define inlet (62) and outlet passages (66), respectively, for flow of process fluid. The first end cap defines flow distributor passages (100) for distributing process fluid across a cross-sectional area of the chamber, and the second end cap defines flow collector passages (104) for collecting process fluid from across a cross-sectional area of the chamber. A clamp is circumferentially located about the cartridge wall for applying a radial load through the wall to the first end cap to fix the first end cap in a desired position.

    摘要翻译： 色谱柱组件包括盒和第一和第二端盖。 筒的壁限定用于容纳色谱介质的室。 端盖分别限定用于工艺流体流动的入口和出口通道。 第一端盖限定了用于在室的横截面区域上分配工艺流体的流量分配器通道，并且第二端盖限定了用于从室的横截面积收集工艺流体的流动收集器通道。 围绕盒壁周向地设置夹具，用于将径向载荷穿过壁施加到第一端盖，以将第一端盖固定在期望的位置。

    A CHROMATOGRAPHY SYSTEM FOR AUTOMATICALLY SEPARATING DIFFERENT COMPOUNDS IN A SAMPLE
    4.
    发明公开
    A CHROMATOGRAPHY SYSTEM FOR AUTOMATICALLY SEPARATING DIFFERENT COMPOUNDS IN A SAMPLE 审中-公开
    色谱各种化合物在样品自动分离的

    公开(公告)号：EP1494775A1

    公开(公告)日：2005-01-12

    申请号：EP03716752.5

    申请日：2003-03-20

    申请人： Biotage, Inc.

    发明人： MICHEL, Jonathan, D. ,  ALBRECHT, Robert, W., Jr.

    IPC分类号： B01D15/08

    CPC分类号： G01N30/82 ,  B01D15/247 ,  G01N30/8627

    摘要： A chromatography system (10) including a chromatography column (18) connected to receive a sample and separate different compounds in the sample, a flow-through detector (10) that outputs a signal indicating the presence of compounds in the sample leaving the column (18), a fraction collector (22) that directs fractions of the sample from the column (18) to separate fraction wells (26), and an electronic controller (28) that receives inputs from the detector (10) and controls the fraction collector (22). The electronic controller (28) monitors the signal from the detector (10) over time and initiates a cut from one well (26) to another at the fraction collector (22) when the signal over time experiences a shoulder where the slope of the signal over time does not change in sign but does change by more than a predetermined amount.