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1.发明公开METHODS AND COMPOSITIONS FOR TREATMENT OF CARTILAGE AND DISC TISSUE PATHOLOGIES 审中-公开VERFAHREN UND ZUSAMMENSETZUNGEN ZUR BEHANDLUNG VON KNORPEL- UND BANDSCHEIBENPATHOLOGIEN
公开(公告)号：EP3039032A4
公开(公告)日：2017-04-19
申请号：EP14839126
申请日：2014-08-27
发明人： MWALE FACKSON , ANTONIOU JOHN , HAGLUND LISBET , ROUGHLEY PETER J , GAWRI RAHUL , EPURE LAURA M , GRANT MICHAEL P
IPC分类号： C07K7/06 , A61K35/32 , A61K38/17 , A61K47/36 , A61P19/00 , A61P19/02 , C07K7/08 , C12N5/077 , C12N5/10 , C12N15/11
摘要： An isolated polypeptide comprising a peptide selected from: i) DHX1SDNYT, wherein X1 is L or H (SEQ ID NO:3); ii) a conservative variant of i) iii) a fragment of i) or ii); wherein the conservative variant and/or fragment retains biological activity and the peptide is 15 or less amino acids as well as recombinant cells, and uses thereof.
摘要翻译： 一种分离的多肽，其包含选自以下的肽：i）DHX1SDNYT，其中X1是L或H（SEQ ID NO：3）; ii）保守变体i）iii）i）或ii）的片段; 其中所述保守变体和/或片段保留生物活性，并且所述肽为15个或更少的氨基酸以及重组细胞及其用途。
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2.发明公开BIOPSY DEVICE AND METHOD FOR OBTAINING A TOMOGRAM OF A TISSUE VOLUME USING SAME 审中-公开活检装置及其制造方法组织体积一层形象，
公开(公告)号：EP3024399A4
公开(公告)日：2017-04-05
申请号：EP14829792
申请日：2014-07-25
申请人： THE ROYAL INST FOR THE ADVANCEMENT OF LEARNING / MCGILL UNIV , UNIV HEALTH NETWORK , POLYVALOR LTD PARTNERSHIP
发明人： LEBLOND FRÉDÉRIC , WILSON BRIAN , GOYETTE ANDRÉANNE , PICHETTE JULIEN , PETRECCA KEVIN , BOUDOUX CAROLINE , MADORE WENDY-JULIE , STRUPLER MATHIAS
CPC分类号： A61B10/04 , A61B1/07 , A61B5/0073 , A61B5/0075 , A61B5/0084 , A61B5/14546 , A61B5/14556 , A61B5/1459 , A61B10/0275 , A61B10/0283 , A61B2010/045
摘要： The biopsy device generally comprises: a cannula body having a longitudinal axis and a probing region extending along the longitudinal axis, the probing region having a sample receiving window defined therein for receiving a sample of a surrounding tissue when performing a biopsy; and a plurality of optical fibers mounted along an exterior portion of the cannula body, each of the plurality of optical fibers having a fiber end in the probing region of the cannula body, at least one of the plurality of optical fibers being adapted to illuminate the surrounding tissue with an optical signal generated by the at least one light generator and at least one of the plurality of optical fibers being adapted to detect an optical signal response with the at least one light detector, the optical signal response being caused by the propagation of the optical signal in the surrounding tissue.
摘要翻译： 所述活检设备基因集会包括：具有纵向轴线和探测区域沿着纵向轴线延伸的插管主体，限定在其中用于接收周围组织当执行活组织检查的样品具有样品接收窗口内的探测区; 以及安装沿着所述套管体，每一个具有在所述套管本体的探测区域中的光纤端部的光纤的多个的外部部分的光纤的复数，光纤是angepasst照亮的多个至少一个 在由所述至少一个光发生器和光学纤维为angepasst在与所述至少一个光检测器的光信号响应于检测的所述多个至少一个产生的光信号与周围组织中，光信号响应由传播引起的 该光信号进入周围组织。
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3.发明公开DETECTION AND MONITORING OF RESISTANCE TO AN IMIDAZOTHIAZOLE ANTI-HELMINTHIC IN NEMATODES 审中-公开检测和监测的咪唑并噻唑ANTIHELMINTHIKUMS线虫
公开(公告)号：EP3019614A4
公开(公告)日：2017-02-15
申请号：EP14823475
申请日：2014-07-11
发明人： PRICHARD ROGER , BARRERE VIRGINIE , BEECH ROBIN , NEVEU CÉDRIC
IPC分类号： C12Q1/68
CPC分类号： C12Q1/6888 , C12Q2600/106 , C12Q2600/156
摘要： The present disclosure concerns the determination of the resistance or the susceptibility of a nematode to an imidazothiazole anti-helmintic based on the assessment of the presence of an indel in the Hco-acr-8 gene (or the Hco-acr-8 gene ortholog). The present disclosure also provides tools and commercial packages for making such assessment.
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4.发明公开BIONANOFLUID FOR USE AS A CONTRAST, IMAGING, DISINFECTING AND/OR THERAPEUTIC AGENT 审中-公开BIONANOFLUID ZUR VERWENDUNG ALS KONTRASTMITTEL，BILDGEBUNG，DESINFEKTIONSMITTEL UND / ODER THERAPEUTIKUM
公开(公告)号：EP3068442A4
公开(公告)日：2017-05-17
申请号：EP14862662
申请日：2014-11-14
发明人： TRIFIRO MARK , PALIOURAS MILTIADIS , ROCHE PHILIP , DOTAN IDIT , BEITEL LENORE , ALVARADO CARLOS , CARNEVALE MATTHEW , MITMAKER ELLIOT JONATHAN
IPC分类号： A61K49/22 , A61K9/10 , A61K41/00 , A61K47/04 , A61K49/08 , C08J3/075 , C08J9/00 , C08K3/04 , C08L89/06
CPC分类号： A61K49/0095 , A01N59/00 , A61K33/44 , A61K41/0028 , A61K47/6851 , A61K47/6903 , A61K47/6905 , A61K49/0093 , A61K49/1803 , A61K49/1806 , A61K49/226 , A61L2/18 , B82Y5/00 , B82Y15/00 , C08J3/075 , C08J2389/00
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公开(公告)号：EP3110824A4
公开(公告)日：2017-11-29
申请号：EP15755646
申请日：2015-02-27
发明人： TREMBLAY MICHEL L , PENAFUERTE CLAUDIA , FELDHAMMER MATTHEW , ZOGOPOULOS GEORGE , BLACK CAMERON , CRANE SHELDON , TRUONG VOUY-LINH , KENNEDY BRIAN
IPC分类号： C07F9/6553 , A61K31/662 , A61K31/67 , A61K35/15 , A61P31/00 , A61P31/18 , A61P33/00 , A61P35/00 , A61P37/02 , C12N5/078 , C12N9/16
CPC分类号： C07F9/655354 , A61K31/662 , A61K31/67 , A61K35/15 , A61K39/0011 , A61K39/39 , A61K45/06 , A61K2039/5154 , C12N9/16 , A61K2300/00
摘要： The invention encompasses the novel class of compounds represented by the Formula (I) below, which are inhibitors of the TC-PTP enzyme. The invention also encompasses pharmaceutical compositions which include the compounds shown above and methods of treating or preventing TC-PTP mediated diseases, including cancer, via their use in the activation of antigen-presenting cells, like dendritic cells, for applications in the immunotherapeutic treatment of diseases.
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6.发明公开CARBONATE-BONDED CONSTRUCTION PRODUCTS FROM STEEL-MAKING RESIDUES AND METHOD FOR MAKING THE SAME 审中-公开CARBONATGEBONDETE KONSTRUKTIONSPRODUKTE AUS STAHLPRODUKTIONSRESTEN UND VERFAHREN ZUR HERSTELLUNG DAVON
公开(公告)号：EP3119730A4
公开(公告)日：2017-04-05
申请号：EP15765421
申请日：2015-03-23
发明人： SHAO YIXIN , MAHOUTIAN MEHRDAD , GHOULEH ZAID
CPC分类号： C04B28/082 , B28B1/14 , B28B11/245 , E04C1/00 , Y02P40/18 , Y02W30/92 , Y02W30/94 , C04B14/12 , C04B40/0082 , C04B40/0231 , C04B14/108 , C04B18/141 , C04B18/142 , C04B14/22 , C04B18/08
摘要： A building product is made from granular material and a binder that includes steel slag. A process for making the building product includes combining the granular material and the binder and then curing the combined granular material and binder with carbon dioxide. A building material includes a mixture of steel slag and a silica-rich material. The steel slag and silica-rich material is treated by heating. The silica-rich material may be waste glass and/or fly ash. A process for making the building material includes mixing the steel slag and silica-rich material and further heating the mixture.
摘要翻译： 建筑产品由粒状材料和包含钢渣的粘合剂制成。 制造建筑产品的方法包括将粒状材料和粘合剂结合，然后用二氧化碳固化组合的粒状材料和粘合剂。 建筑材料包括钢渣和富含二氧化硅的材料的混合物。 钢渣和富含二氧化硅的材料通过加热进行处理。 富含二氧化硅的材料可以是废玻璃和/或粉煤灰。 制造建筑材料的方法包括混合钢渣和富含二氧化硅的材料并进一步加热混合物。
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