公开(公告)号：EP3389737A1

公开(公告)日：2018-10-24

申请号：EP17702290.2

申请日：2017-01-23

申请人： Gyrus ACMI, Inc. (D.B.A. Olympus Surgical Technologies America)

发明人： FAN, Tailin

IPC分类号： A61M1/00 ,  A61B17/22

CPC分类号： A61B17/22 ,  A61B2017/22079 ,  A61B2090/064 ,  A61B2217/005 ,  A61B2217/007 ,  A61M1/0084 ,  A61M3/0216 ,  A61M3/022 ,  A61M3/0283 ,  A61M2210/1082 ,  A61M2210/1085 ,  A61M2210/1089

摘要： Disclosed is a medical device or system comprising an elongate member having a distal end and a proximal end; an inflow lumen disposed within the elongate member, the inflow lumen having a proximal end, a distal end and a slanting exit opening at the distal end of the inflow lumen; and an outflow lumen also disposed within the elongate member, the outflow lumen having a proximal end, a distal end and a slanting receiving opening at the distal end of the outflow lumen. The disclosed medical device or system further comprises pressure sensors disposed at the distal end of the elongate member. Also disclosed is a method of employing the above disclosed device or variations thereof to remove small stones or small stone fragments from within the body's lumen or internal organ of a subject.

公开(公告)号：EP3039138A4

公开(公告)日：2017-04-26

申请号：EP14840753

申请日：2014-09-02

申请人： UNIV INDIANA RES & TECH CORP

发明人： BACALLAO ROBERT

IPC分类号： C12N15/00 ,  A61B5/0215 ,  A61K35/00 ,  A61K38/00 ,  A61K38/18 ,  A61M5/145 ,  A61M25/00 ,  A61M25/10

CPC分类号： A61M25/10184 ,  A61B5/0215 ,  A61K35/00 ,  A61K38/00 ,  A61M5/1452 ,  A61M25/1002 ,  A61M25/1011 ,  A61M25/10188 ,  A61M2025/0002 ,  A61M2025/1047 ,  A61M2025/1052 ,  A61M2025/1093 ,  A61M2205/3331 ,  A61M2210/1082 ,  A61M2230/005 ,  A61M2230/30

公开(公告)号：EP2836113A1

公开(公告)日：2015-02-18

申请号：EP13775312.5

申请日：2013-03-15

申请人： Medtronic Inc.

发明人： BURNES, John ,  MANDA, Venkatesh ,  VAN ANTWERP, William ,  WILLIAMS, Jamie

IPC分类号： A61B5/02 ,  A61M5/00

CPC分类号： A61M5/1723 ,  A61B5/4836 ,  A61M5/14244 ,  A61M5/14276 ,  A61M2205/3523 ,  A61M2205/50 ,  A61M2205/52 ,  A61M2210/1082 ,  A61M2210/125 ,  A61M2230/005 ,  A61M2230/30 ,  G06F19/00 ,  G06F19/3462 ,  G16H40/63

摘要： Devices, systems and methods using feedback from sensors for the treatment of pathological conditions such as Kidney Disease (KD) alone, Heart Failure (HF) alone, KD with concomitant HF or cardiorenal diseases syndrome (CRS) are described. The devices, systems and methods monitor and gather patient information and administer one or more diuretic or natriuretic molecules.

公开(公告)号：EP1996278A4

公开(公告)日：2010-06-02

申请号：EP07757925

申请日：2007-03-05

申请人： ARDIAN INC

发明人： DEMARAIS DENISE ,  GIFFORD HANSON III ,  DEEM MARK ,  SUTTON DOUGLAS ,  LEVIN HOWARD R ,  GELFAND MARK

IPC分类号： A61N1/00

CPC分类号： A61N1/0551 ,  A61B18/12 ,  A61B18/14 ,  A61B18/1492 ,  A61B2018/00267 ,  A61B2018/00351 ,  A61B2018/00404 ,  A61B2018/00434 ,  A61B2018/00511 ,  A61B2018/00577 ,  A61B2018/00613 ,  A61M5/1408 ,  A61M5/14276 ,  A61M2210/1082 ,  A61N1/0412 ,  A61N1/05 ,  A61N1/327 ,  A61N1/36007 ,  A61N1/36017 ,  A61N7/00

摘要： Apparatus are provided for bilateral renal neuromodulation, e.g. via a pulsed electric field, via a stimulation electric field, via localized drug delivery, via high frequency ultrasound, via thermal techniques, etc. Such neuromodulation may effectuate irreversible electroporation or electrofusion, necrosis and/or inducement of apoptosis, alteration of gene expression, action potential attenuation or blockade, changes in cytokine up-regulation and other conditions in target neural fibers. In some embodiments, neuromodulation is applied to neural fibers that contribute to renal function. In some embodiments, such neuromodulation is performed in a bilateral fashion. Bilateral renal neuromodulation may provide enhanced therapeutic effect in some patients as compared to renal neuromodulation performed unilaterally, i.e. as compared to renal neuromodulation performed on neural tissue innervating a single kidney.

摘要翻译： 提供了用于双侧肾神经调节的装置，例如 通过脉冲电场，经由局部药物递送，经由高频超声，经由热技术等经由刺激电场。这种神经调节可以实现不可逆的电穿孔或电融合，坏死和/或诱导凋亡，基因表达的改变， 动作电位衰减或阻断，细胞因子上调和目标神经纤维中的其他条件的变化。 在一些实施方案中，神经调节被应用于有助于肾功能的神经纤维。 在一些实施方案中，这种神经调节以双向方式进行。 与单侧执行的肾神经调节相比，即与在神经组织支配单肾中进行的肾神经调节相比，双侧肾神经调节可在一些患者中提供增强的治疗效果。

公开(公告)号：EP1434610A1

公开(公告)日：2004-07-07

申请号：EP02801624.4

申请日：2002-08-29

申请人： Applied Medical Resources Corporation

发明人： LANDMAN, Jaime ,  CLAYMAN, Ralph V. ,  EWERS, Richard C.

IPC分类号： A61M1/00 ,  A61M3/00

CPC分类号： A61M25/007 ,  A61M25/0032 ,  A61M25/0041 ,  A61M25/0068 ,  A61M27/008 ,  A61M31/00 ,  A61M2025/0004 ,  A61M2025/0034 ,  A61M2025/0073 ,  A61M2025/0681 ,  A61M2205/3331 ,  A61M2210/1082

摘要： A high-flow low-pressure irrigation system (10) for directing a fluid to and recovering the fluid from an area within a body, the irrigation system (10) comprising a sheath (37) and a flexible catheter (20) disposed in the sheath (37). The catheter (20) comprises a plurality of apertures (26) at a distal pigtail portion (28). The fluid is directed through the apertures (26) and recovered through the sheath (37). Renal applications include alkaline irrigation for dissolution of uric acid stones, chemo-dissolution of cystine stones, irrigation with chemotherapy drugs after ureteroscopic tumor management, antibiotic irrigation for severe infection (e.g., fungal and bacterial), and irrigation of thrombotic agents (Alum or direct delivery of Amicar for renal bleeding).

公开(公告)号：EP1278563A2

公开(公告)日：2003-01-29

申请号：EP01930872.5

申请日：2001-04-27

申请人： Libra Medical Systems, Inc.

发明人： KEREN, Gad ,  SHMULEWITZ, Ascher ,  SPENSER, Benjamin ,  ARAD, Michael ,  KESTEN, Randy, J. ,  PESOTCHINSKY, Sophia ,  ROSENTHAL, Michael, H. ,  KRAMER, Andrew, W. ,  PAYNE, Sam, G.

IPC分类号： A61M1/36

CPC分类号： A61M25/00 ,  A61B17/12013 ,  A61B2017/00243 ,  A61B2017/061 ,  A61B2017/22054 ,  A61F2002/068 ,  A61M1/101 ,  A61M1/1018 ,  A61M1/1034 ,  A61M1/106 ,  A61M1/107 ,  A61M1/1072 ,  A61M1/1096 ,  A61M1/122 ,  A61M1/125 ,  A61M1/3653 ,  A61M1/3659 ,  A61M25/0075 ,  A61M25/10 ,  A61M25/1011 ,  A61M2025/1052 ,  A61M2210/1082 ,  A61M2210/125

摘要： Methods and apparatus are provided for treating congestive heart by actively or passively enhancing perfusion to the renal arteries. A first embodiment comprises a specially configured balloon catheter and extracorporeal pump, wherein the pump operates in a 'once-through' fashion or alternating volume displacement mode. In another embodiment the catheter includes a pair of balloons to isolate a region of the aorta, and a third balloon that directs flow into the renal arteries. In still further embodiments, a stent or cuff having a constricted region is deployed in or around the aorta, respectively, to create a backpressure upstream of the stent or cuff. Methods of enhancing renal perfusion also are provided.

公开(公告)号：EP3086834A4

公开(公告)日：2018-01-03

申请号：EP14875849

申请日：2014-12-23

申请人： RENALPRO MEDICAL INC

发明人： LEE TSUNG-CHUN ,  SHIH WEN-PIN

IPC分类号： A61M25/00 ,  A61B17/12

CPC分类号： A61M25/1011 ,  A61B17/12036 ,  A61B17/1204 ,  A61B17/12109 ,  A61B17/12136 ,  A61B2090/063 ,  A61B2090/064 ,  A61M1/1001 ,  A61M1/1008 ,  A61M1/101 ,  A61M1/1034 ,  A61M1/1056 ,  A61M1/106 ,  A61M1/1072 ,  A61M1/1086 ,  A61M1/12 ,  A61M1/122 ,  A61M1/125 ,  A61M5/007 ,  A61M2025/0002 ,  A61M2025/0073 ,  A61M2025/1052 ,  A61M2025/1079 ,  A61M2025/1095 ,  A61M2205/32 ,  A61M2205/3327 ,  A61M2210/1082 ,  A61M2210/12

摘要： A catheter devices/systems and methods therefrom are described herein for treating acute kidney injury, especially the contrast-induced acute kidney injury wherein the devices prevent the contrast dyes from entering into kidney and/or facilitate blood flow of kidney by said catheter system.

公开(公告)号：EP1996278B1

公开(公告)日：2017-08-30

申请号：EP07757925.8

申请日：2007-03-05

申请人： Medtronic Ardian Luxembourg S.à.r.l.

发明人： DEMARAIS, Denise ,  GIFFORD, Hanson, III ,  DEEM, Mark ,  SUTTON, Douglas ,  LEVIN, Howard, R. ,  GELFAND, Mark

IPC分类号： A61N1/00 ,  A61N1/04 ,  A61N7/00 ,  A61N1/05 ,  A61N1/32 ,  A61N1/36 ,  A61B18/00 ,  A61M5/14 ,  A61B18/14 ,  A61B18/12 ,  A61M5/142

CPC分类号： A61N1/0551 ,  A61B18/12 ,  A61B18/14 ,  A61B18/1492 ,  A61B2018/00267 ,  A61B2018/00351 ,  A61B2018/00404 ,  A61B2018/00434 ,  A61B2018/00511 ,  A61B2018/00577 ,  A61B2018/00613 ,  A61M5/1408 ,  A61M5/14276 ,  A61M2210/1082 ,  A61N1/0412 ,  A61N1/05 ,  A61N1/327 ,  A61N1/36007 ,  A61N1/36017 ,  A61N7/00

摘要： Apparatus are provided for bilateral renal neuromodulation, e.g. via a pulsed electric field, via a stimulation electric field, via localized drug delivery, via high frequency ultrasound, via thermal techniques, etc. Such neuromodulation may effectuate irreversible electroporation or electrofusion, necrosis and/or inducement of apoptosis, alteration of gene expression, action potential attenuation or blockade, changes in cytokine up-regulation and other conditions in target neural fibers. In some embodiments, neuromodulation is applied to neural fibers that contribute to renal function. In some embodiments, such neuromodulation is performed in a bilateral fashion. Bilateral renal neuromodulation may provide enhanced therapeutic effect in some patients as compared to renal neuromodulation performed unilaterally, i.e. as compared to renal neuromodulation performed on neural tissue innervating a single kidney.

摘要翻译： 提供用于双侧肾神经调节的装置，例如， 通过脉冲电场，经由刺激电场，经由局部药物递送，经由高频超声，经由热技术等。这种神经调节可以实现不可逆的电穿孔或电融合，细胞凋亡的坏死和/或诱导，基因表达的改变， 动作电位衰减或阻断，细胞因子上调和目标神经纤维中其他条件的变化。 在一些实施方案中，神经调节应用于有助于肾功能的神经纤维。 在一些实施方案中，这种神经调节以双边方式进行。 与单侧进行的肾神经调节相比，与在支配单一肾的神经组织上进行的肾神经调节相比，双侧肾神经调节可以在一些患者中提供增强的治疗效果。

公开(公告)号：EP2977074A1

公开(公告)日：2016-01-27

申请号：EP14178201.1

申请日：2014-07-23

申请人： Coloplast A/S

发明人： Seguy, Sebastien ,  Beilvert, Thomas ,  Millet, Jacques ,  Bougherara, Chaabane ,  Chouarche, Olivier

IPC分类号： A61M27/00

CPC分类号： A61M27/008 ,  A61F2002/048 ,  A61F2250/0029 ,  A61M2210/1078 ,  A61M2210/1082

摘要： Disclosed is a ureteral stent (10) having a body (11) and a tail (12). The body of the stent has a renal area (13) intended to be placed in a kidney of a patient, a ureteral area (15) intended to be placed in at least part of a ureter of the patient, and a proximal area (16) arranged at a proximal end of the body of the stent. The tail has at least one thread intended to end in the bladder of the patient. The proximal area (16) is tubular, has a cylindrical shape and is of annular cross section, and has a flexibility greater than the flexibility of the ureteral area of the stent.

摘要翻译： 公开了一种具有主体（11）和尾部（12）的输尿管支架（10）。 支架的主体具有用于放置在患者的肾脏中的肾区域（13），用于放置在患者的输尿管的至少一部分中的输尿管区域（15），和用于放置在患者的肾脏中的近端区域（16 ）布置在支架的主体的近端处。 尾部至少有一根线用于结束患者的膀胱。 近侧区域（16）是管状的，具有圆柱形形状并且具有环形横截面，并且具有比支架的输尿管区域的柔性更大的柔性。

公开(公告)号：EP2313008A1

公开(公告)日：2011-04-27

申请号：EP09798735.8

申请日：2009-07-16

申请人： Wake Forest University Health Sciences

发明人： ARGENTA, Louis, C. ,  CARROLL, David, L. ,  LEVI, Nicole, H. ,  LIU, Jie ,  MORYKWAS, Michael, J. ,  JORDAN, James, E. ,  WAGNER, William, D.

IPC分类号： A61B17/00

CPC分类号： A61B17/00234 ,  A61B90/06 ,  A61B2017/00243 ,  A61B2017/306 ,  A61B2090/064 ,  A61F13/00068 ,  A61F2013/0028 ,  A61M1/0031 ,  A61M1/0037 ,  A61M1/0088 ,  A61M2210/1082 ,  A61M2210/125

摘要： A method and apparatus are provided for treating cardiac tissue to modulate ischemic heart tissue with topical sub-atmospheric pressure to minimize cell death and damage.