摘要:
Systems, devices, and methods for electroporation ablation therapy are disclosed, with the system including a pulse waveform signal generator for medical ablation therapy, and an endocardial ablation device includes at least one electrode for ablation pulse delivery to tissue. The signal generator may deliver voltage pulses to the ablation device in the form of a pulse waveform. The system may include a cardiac stimulator for generation of pacing signals and for sequenced delivery of pulse waveforms in synchrony with the pacing signal.
摘要:
A catheter including an elongated shaft having a distal end and a proximal end, where the catheter includes a thermal element at the distal end thereof. The thermal element may be used in an ablation procedure or other procedure to heat a tissue adjacent a vessel. In some instances, the thermal element may be positioned in a first vessel and may operate to heat tissue adjacent a second vessel or adjacent an ostium between the first vessel and the second vessel. Further, the catheter may include an expandable portion on which the thermal element may be connected or positioned. The expandable portion(s) may comprise a basket or cage, a balloon, a memory shape and formable portion, and/or other mechanical expanders.
摘要:
A tissue segmentation device, controller, and methods therefore are disclosed. The device has an active electrode, a return electrode, a mechanical force application mechanism, voltage and current sensors, and a controller. The controller is configured to control a power output of the segmentation device. The controller has a processing component, responsive to the sensors, configured to execute the following: (a) derive a power factor of power applied to the at least one electrode; and (b) responsive to the deriving a power factor, assign a circuit status to a circuit comprising the at least one electrode. IF (PF≈0) and ((Vrms/Irms)≧T), THEN the circuit status is “open”. IF (PF≈0) and ((Vrms/Irms)
摘要:
A catheter adapted for mapping and/or ablation in the atria has a basket-shaped electrode array with two or more location sensors with a deflectable expander. The catheter has comprises a catheter body, a basket electrode assembly at a distal end of the catheter body, and a control handle at a proximal end of the catheter body. The basket electrode assembly has a plurality of electrode-carrying spines and an expander that is adapted for longitudinal movement relative to the catheter body for expanding and collapsing the assembly via a proximal end portion extending past the control handle that can be pushed or pulled by a user. The expander is also adapted for deflection in responsive to an actuator on the control handle that allows a user to control at least one puller wire extending through the catheter body and the expander.
摘要:
This disclosure includes a hybrid electrode assembly mounted at the distal end of the catheter body having at least two spines and an inflatable balloon such that the inflatable balloon is disposed within the spines when in an expanded arrangement. The hybrid electrode assembly has a non-projecting distal portion when in the expanded arrangement.
摘要:
Methods and apparatus are provided for renal neuromodulation using a pulsed electric field to effectuate electroporation or electrofusion. It is expected that renal neuromodulation (e.g., denervation) may, among other things, reduce expansion of an acute myocardial infarction, reduce or prevent the onset of morphological changes that are affiliated with congestive heart failure, and/or be efficacious in the treatment of end stage renal disease. Embodiments of the present invention are configured for percutaneous intravascular delivery of pulsed electric fields to achieve such neuromodulation.
摘要:
Cardiac mapping catheters and methods for using the catheters are described. The catheter can detect the presence, direction and/or source of a depolarization wave front associated with cardiac arrhythmia. A mapping catheter includes a plurality of bipolar electrode pairs in which the members of each pair are opposed to one another across a perimeter, for instance in a circular pattern. The spaced arrangement of the electrodes can be utilized to identify directional paths of moving electric fields or wave fronts in any direction passing across the endocardial surface. The catheters can be used to identify locations and types of triggers and/or drivers of cardiac arrhythmia including rotors, ectopic trigger foci and/or to delineate reentrant pathways.
摘要:
Methods and apparatus are provided for renal neuromodulation using a pulsed electric field to effectuate electroporation or electrofusion. It is expected that renal neuromodulation (e.g., denervation) may, among other things, reduce expansion of an acute myocardial infarction, reduce or prevent the onset of morphological changes that are affiliated with congestive heart failure, and/or be efficacious in the treatment of end stage renal disease. Embodiments of the present invention are configured for percutaneous intravascular delivery of pulsed electric fields to achieve such neuromodulation.
摘要:
The present invention concerns an elongated medical device (1, 11) suitable for intravascular insertion. Said device comprising a flexible elongated body (2) having a distal portion (3) with a distal end (4) and a proximal portion (5), and an electrode assembly (80) located at the distal portion (3). The electrode assembly (80) comprises a plurality of at least x=4 support arms (81), wherein x is evenly divisible by the number 2, each support arm (81) having a proximal end part (81 a), a distal end part (81 b) and a main part (81 c) between the proximal end part (81 a) and the distal end part (81 b), the plurality of at least x=4 support arms (81) comprising first and second neighboring support arms (81.1, 81.2) forming pairs of neighboring support arms (81). The electrode assembly (80) further comprises a plurality of electrodes (82) arranged on the support arms (81) for collecting electrophysiological data. The plurality of at least x=4 support arms (81) is configured to have a first condition (UC), where the plurality of at least x=4 support arms (81) is arranged in a bundle, and a second condition (EC), where the plurality of at least x=4 support arms (81) is expanded, forming a basket type structure (83). All first and second neighboring support arms (81.1, 81.2) are combined at their proximal end parts (81 a) to form united end parts (88a), such that all pairs of neighboring support arms (81) are united at their proximal end parts (81 a). Further, each second and first neighboring support arms (81.2, 81.1) are combined at their distal end parts (81 b), to form united end parts (88b), such that all pairs of neighboring support arms (81) are united at their distal end parts (81 b), wherein each support arm (81) is combined at its distal end part (81 b) with a different neighboring support arm (81) than at its proximal end part (81 a).
摘要:
An expandable electrode assembly for use in a cardiac mapping procedure includes multiple bipolar electrode pairs including a first electrode located on an outer surface and a second electrode located on an inner surface of the individual splines forming the expandable electrode assembly. Such an electrode arrangement may produce improved electrical activation signals which may be used to produce a more accurate map of the electrical activity of a patient's heart.