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公开(公告)号：EP3345872A1
公开(公告)日：2018-07-11
申请号：EP16842407.5
申请日：2016-07-21
Applicant: Electrophor, Inc.
CPC classification number: B01D61/12 , B01D61/00 , B01D61/025 , B01D61/027 , B01D61/08 , B01D65/02 , B01D2311/14 , B01D2311/25 , B01D2311/2619 , B01D2321/02 , C02F1/008 , C02F1/32 , C02F1/44 , C02F1/441 , C02F1/442 , C02F2103/08 , C02F2201/005 , C02F2209/03 , C02F2301/046 , C02F2303/04 , C02F2303/16 , Y02A20/131
Abstract: The invention relates to systems for purifying and/or desalinating a liquid. The present system comprises a valved raw liquid supply line, which is connected to a filtration unit comprising a liquid purification means with an inlet and with outlets for purified liquid and drain liquid, a mixing device, a means for maintaining pressure, a means for maintaining a recirculating flow of liquid, which is located on a line supplying a mixture of raw liquid and concentrate upstream of the liquid purification means, a recirculating line, a purified liquid line, a drain liquid line, and a control unit, which is connected to all of the following: the means for maintaining pressure, a means for monitoring changes in pressure, the raw liquid supply valve and a drain liquid discharge valve. The means for maintaining pressure is located on a raw liquid supply line upstream of the liquid mixing device, which is in the form of a head tank connected to a raw liquid and concentrate mixing line. The technical result is a longer system working life, more efficient use of raw liquid, and reduced energy expenditure.
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公开(公告)号：EP3337598A1
公开(公告)日：2018-06-27
申请号：EP16757599.2
申请日：2016-08-17
Applicant: GE Healthcare Bio-Sciences AB
Inventor： NUTALAPATI, Sasi, Kumar , GEBAUER, Klaus , LIDERFELT, Karl, Axel, Jakob , KARMARKAR, Nachiket , VERNEKAR, Ajit S. , SHARMA, Amit, Kumar , LUNDSTROM, Fredrik, Oskar
CPC classification number: B01D61/18 , B01D61/08 , B01D61/10 , B01D61/12 , B01D61/20 , B01D61/22 , B01D65/02 , B01D2311/08 , B01D2311/16 , B01D2311/25 , B01D2313/243 , B01D2315/10 , B01D2315/14 , B01D2321/02 , C07K1/34
Abstract: The disclosed subject matter relates to an automated CFF/TFF system that provides the operations of system treatment with a system treatment solution(such as buffer) and filtration of a solution (e.g., a biofluid) can be accomplished in succession without having to re-configure the system (such as re-routing the fluid conduits) that could compromise the integrity of the system. As a result, there will be reduced contamination risk, reduced volume of buffer required and will save time for the filtration process.
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3.发明公开LIQUID TO LIQUID BIOLOGICAL PARTICLE FRACTIONATION AND CONCENTRATION 审中-公开液体在液体中，生物粒子，分级及-KONZENTRIERUNG
公开(公告)号：EP2984467A4
公开(公告)日：2017-01-04
申请号：EP13846911
申请日：2013-10-18
Applicant: INNOVAPREP LLC
Inventor： PACKINGHAM ZACHARY A , PAGE ANDREW EDWARD , ALBURTY DAVID SCOTT , GRAHAM STEVEN DALE , ADOLPHSON ALEC DOUGLAS
CPC classification number: G01N1/405 , B01D61/20 , B01D61/22 , B01D63/082 , B01D63/088 , B01D2315/08 , B01D2319/06 , B01D2321/02 , G01N1/40 , G01N1/4055 , G01N1/4077 , G01N2001/4016 , G01N2001/4038 , G01N2001/4088
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公开(公告)号：EP2641652A3
公开(公告)日：2014-01-08
申请号：EP13172548.3
申请日：2008-09-12
Applicant: Danisco US Inc.
Inventor： BECKER, Nathaniel T. , BRAUN, Ryszard , CHRISTENSEN, Robert I. , EKBOM, Stefan , FONG, Robin , SCHULER, Alexandra
CPC classification number: B01D65/00 , B01D61/14 , B01D63/10 , B01D65/02 , B01D65/08 , B01D2311/06 , B01D2313/19 , B01D2321/02 , B01D2321/04 , B01D2321/10 , B01D2321/12 , B01D2321/20 , B01D2321/2008 , B01D2321/2083 , B01D2311/14 , B01D2311/165
Abstract: Filtration processes and systems are provided for the separation of a filterable fluid stream by a filtration membrane module with uniform transmembrane pressure and flux along the membrane and internal control of membrane fouling via intermittent periodic reduction of the pressure differential between the permeate and retentate sides of the membrane and/or backwashing cycles during separation, recovery, and/or purification of proteins, peptides, nucleic acids, biologically produced polymers and other compounds or materials from aqueous fluids.
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5.发明公开
公开(公告)号：EP1968724A1
公开(公告)日：2008-09-17
申请号：EP06818160.1
申请日：2006-12-08
Applicant: Tetra Laval Holding & Finance S.A.
Inventor： HANSEN, Svend, Emil, Himmelstrup
CPC classification number: B01D37/04 , B01D61/147 , B01D61/22 , B01D65/02 , B01D2311/02 , B01D2311/16 , B01D2321/02 , B01D2325/28
Abstract: There is described a method for the starting up of a filtration plant for the filtration of a process liquid, after cleaning of the filtration plant, and a filtration plant which is arranged to be able to started up in accordance with this method. A secondary liquid supply unit connected to the post-treatment equipment during the starting up of the plant provides a flow of e.g. sterilised water to the post-treatment equipment, so that this can be held in a condition in which it is ready for operation. Thereafter, the process liquid is led to the filtration equipment, and the flow of liquid from the secondary liquid supply unit to the post-treatment equipment is shut off when a flow of filtered process liquid is obtained, and which thereafter replaces the liquid from the secondary liquid supply unit.
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Patent Agency Ranking6.发明公开Apparatus and method for mixing specimens in vials 审中-公开Vorrichtung und Verfahren zum Mischen von Proben在Phiolen
公开(公告)号：EP1845357A1
公开(公告)日：2007-10-17
申请号：EP07012473.0
申请日：2002-10-21
Applicant: MonoGen, Inc.
Inventor： Mayer, William, J.
CPC classification number: B01D61/18 , B01D61/22 , B01D63/08 , B01D65/08 , B01D2321/02 , B01F7/00583 , B01F7/1695 , B01F13/002 , B01F13/04 , B01F13/045 , B01L3/502 , B01L3/508 , B01L3/50825 , B01L2300/042 , B01L2300/046 , B01L2300/0681 , B65B7/161 , B65B69/00 , G01N1/2813 , G01N1/4077 , G01N27/22 , G01N35/00 , G01N35/00029 , G01N35/0099 , G01N35/021 , G01N35/1016 , G01N2001/1025 , G01N2001/2826 , G01N2035/00089 , G01N2035/00138 , G01N2035/0405 , G01N2035/0427 , G01N2035/0441 , G01N2035/0443 , G01N2035/0458 , G01N2035/0462
Abstract: Method and apparatus for mixing a specimen (e.g. a biological fluid specimen) in an upstanding container having an internal mixer with a cavity defined by an upstanding annular wall. The annular wall of the mixer is engaged by a movable holder, which is elevated along with the engaged mixer sufficiently to prevent contact of the mixer with the container during mixing. The mixer is then moved to mix the specimen. The holder, which may include an expanding collet that fits within the cavity of the mixer, preferably rotates the mixer to stir the specimen. When mixing is complete, the holder is disengaged from the mixer. A controller coordinates all actions of the holder.
Abstract translation: 用于将具有内部混合器的直立容器中的样本（例如生物流体样本）与由直立的环形壁限定的空腔混合的方法和装置。 混合器的环形壁由可移动的保持器接合，可移动的保持器与接合的混合器一起被充分地升高以防止混合器在混合期间与容器接触。 然后将混合器移动以混合样品。 可以包括装配在混合器的空腔内的膨胀夹头的保持器优选地旋转混合器以搅拌样品。 当混合完成时，保持器与混合器脱开。 控制器协调持有者的所有动作。
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公开(公告)号：EP1438562B1
公开(公告)日：2007-06-27
申请号：EP02789228.0
申请日：2002-10-21
Applicant: MonoGen, Inc.
Inventor： MAYER, William, J. , WROBLEWSKI, Lucien, J.
CPC classification number: G01N1/4077 , B01D61/18 , B01D61/22 , B01D63/08 , B01D65/08 , B01D2321/02 , B01D2321/10 , B01D2321/16 , B01D2321/2008 , B01D2321/2016 , B01D2321/2066 , B01F7/00583 , B01F7/1695 , B01F13/002 , B01F13/04 , B01F13/045 , B01L3/502 , B01L3/508 , B01L3/50825 , B01L9/06 , B01L9/52 , B01L2200/025 , B01L2300/042 , B01L2300/044 , B01L2300/046 , B01L2300/0681 , B01L2300/0822 , B01L2300/0851 , B65B7/161 , B65B69/00 , G01N1/2813 , G01N27/22 , G01N35/00 , G01N35/00029 , G01N35/0099 , G01N35/021 , G01N35/04 , G01N35/1016 , G01N2001/1025 , G01N2001/2826 , G01N2035/00089 , G01N2035/00138 , G01N2035/0405 , G01N2035/0427 , G01N2035/0441 , G01N2035/0443 , G01N2035/0458 , G01N2035/0462 , Y10T29/49822 , Y10T29/53039 , Y10T436/11 , Y10T436/112499 , Y10T436/113332 , Y10T436/12 , Y10T436/25375 , Y10T436/255
Abstract: Method and apparatus for storing and dispensing articles, one at a time, from the bottom of a stack of like articles. The articles are yieldably supported in at least one upright stack above an outlet, e.g., a resilient choke, sized to pass the articles if forced therethrough. Articles are dispensed by pressing downwardly on the stack with sufficient force and for sufficient duration to overcome the yieldable supporting force and move the lowest article through the outlet. Sensors may be provided for sensing when an article is dispensed, when the tube is empty, and the type of article in the holder. The method and apparatus are especially useful in a vial-based automated system for processing multiple specimens of biological fluid, wherein a filter assembly must be dispensed into a filtration chamber associated with each specimen vial.
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8.发明授权FLOW CONTROL METERING SYSTEM AND METHOD FOR CONTROLLING FILTRATION OF LIQUID-BASED SPECIMENS 有权测量流量控制制度和相关程序受控过滤液体样品
公开(公告)号：EP1438559B1
公开(公告)日：2007-06-20
申请号：EP02773810.3
申请日：2002-10-21
Applicant: MonoGen, Inc.
Inventor： PRESSMAN, Norman, J. , MAYER, William, J. , WROBLEWSKI, Lucien, J.
IPC: G01N1/28
CPC classification number: G01N1/4077 , B01D61/18 , B01D61/22 , B01D63/08 , B01D65/08 , B01D2321/02 , B01D2321/10 , B01D2321/16 , B01D2321/2008 , B01D2321/2016 , B01D2321/2066 , B01F7/00583 , B01F7/1695 , B01F13/002 , B01F13/04 , B01F13/045 , B01L3/502 , B01L3/508 , B01L3/50825 , B01L9/06 , B01L9/52 , B01L2200/025 , B01L2300/042 , B01L2300/044 , B01L2300/046 , B01L2300/0681 , B01L2300/0822 , B01L2300/0851 , B65B7/161 , B65B69/00 , G01N1/2813 , G01N27/22 , G01N35/00 , G01N35/00029 , G01N35/0099 , G01N35/021 , G01N35/04 , G01N35/1016 , G01N2001/1025 , G01N2001/2826 , G01N2035/00089 , G01N2035/00138 , G01N2035/0405 , G01N2035/0427 , G01N2035/0441 , G01N2035/0443 , G01N2035/0458 , G01N2035/0462 , Y10T29/49822 , Y10T29/53039 , Y10T436/11 , Y10T436/112499 , Y10T436/113332 , Y10T436/12 , Y10T436/25375 , Y10T436/255
Abstract: A method and apparatus for collecting a cell sample of desired concentration on a filter collection site from a biological liquid specimen in a container. Specimen liquid is moved through a filter while the volume rate of liquid flow through the filter is monitored. The monitored liquid flow rate is compared to a reference value, and liquid flow through the filter is terminated when the ratio value. The predetermined ratio value preferably is a function of the protocol for processing the specimen. An alternative method and apparatus relies on the rate of change of the measured weight of the container. This rate is compared to a reference value, and liquid flow through the filter is terminated when the rate of change diminishes to or below a predetermined value.
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公开(公告)号：EP0784502B1
公开(公告)日：2007-03-07
申请号：EP96928087.4
申请日：1996-08-02
Applicant: RENSSELAER POLYTECHNIC INSTITUTE
Inventor： BELFORT, Georges
CPC classification number: B01D65/08 , B01D63/025 , B01D63/027 , B01D63/068 , B01D2321/02 , B01D2321/2016
Abstract: A method and apparatus for achieving reverse osmosis, microfiltration, nanofiltration and ultrafiltration, produces Dean vortices against a membrane surface which is advantageously in a form of a wound helical membrane tube (34).
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10.发明公开
公开(公告)号：EP1609522A3
公开(公告)日：2006-02-01
申请号：EP05253940.0
申请日：2005-06-24
Applicant: MILLIPORE CORPORATION
Inventor： Tkacik, Gabriel , Goddard, Philip , Kools, Willem Franciscus Catherina , Nitin, Satav
CPC classification number: B01D69/125 , A61L2/0017 , A61L2/022 , A61M1/34 , A61M2205/3368 , B01D61/145 , B01D63/067 , B01D65/02 , B01D67/0013 , B01D67/0016 , B01D69/02 , B01D69/12 , B01D71/68 , B01D2321/02 , B01D2321/04 , B01D2321/168 , B01D2325/022 , B01D2325/04
Abstract: The present invention is an integral multilayered composite membrane having at least one ultrafiltration layer made by cocasting or sequentially casting a plurality of polymer solutions onto a support to form a multilayered liquid sheet and immersing the sheet into a liquid coagulation bath to effect phase separation and form a multilayered composite membrane having at least one ultrafiltration layer.
Asymmetric ultrafiltration layer exposes wider pore side to feed. Separation of viruses and proteins are carried out using hydrophilic polymers.
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