公开(公告)号：EP1355895B1

公开(公告)日：2008-07-23

申请号：EP01993241.7

申请日：2001-12-07

申请人： The Government of the United States of America, as represented by the Secretary, Department of Health & Human Services

发明人： MAUPIN, Gary, O. ,  KARCHESY, Joseph ,  PANELLA, Nicholas, A. ,  DOLAN, Marc, C.

IPC分类号： C07D303/04 ,  C07D303/32 ,  C07C33/14 ,  C07C47/225 ,  A01N31/04 ,  A01N43/20

CPC分类号： C07D303/32 ,  A01N27/00 ,  A01N31/04 ,  A01N31/06 ,  A01N43/20 ,  C07C33/14 ,  C07C45/28 ,  C07C45/78 ,  C07C47/225 ,  C07C47/267 ,  C07C47/46 ,  C07C47/47 ,  C07C49/21 ,  C07C49/242 ,  C07C49/258 ,  C07C49/583 ,  C07C49/733 ,  C07C49/757 ,  C07D303/04 ,  Y02A40/166

摘要： Compounds, compositions, and methods for controlling an arthropod pest population that employ an eremophilane sesquiterpene parent structure are presented. The compounds have minimal adverse or toxic effects on humans, non-human animals, and the natural environment. The compounds may be isolated from natural sources, semi-synthesized from naturally occurring compounds, or completely synthesized. The compounds may be applied directly to a pest, or the locus of a pest, and function as topical or ingestible toxins. Eremophilane sesquiterpenes 13-hydroxy-valencene, valencene-11,12-epoxide, valencene-13-aldehyde, and nootkatone-1,10-11,12-diepoxide are exemplary compounds.

公开(公告)号：EP1355895A2

公开(公告)日：2003-10-29

申请号：EP01993241.7

申请日：2001-12-07

申请人： The Government of the United States of America, as represented by the Secretary, Department of Health & Human Services

发明人： MAUPIN, Gary, O. ,  KARCHESY, Joseph ,  PANELLA, Nicholas, A. ,  DOLAN, Marc, C.

IPC分类号： C07D303/04 ,  C07D303/32 ,  C07C33/14 ,  C07C47/225 ,  A01N31/04 ,  A01N43/20

CPC分类号： C07D303/32 ,  A01N27/00 ,  A01N31/04 ,  A01N31/06 ,  A01N43/20 ,  C07C33/14 ,  C07C45/28 ,  C07C45/78 ,  C07C47/225 ,  C07C47/267 ,  C07C47/46 ,  C07C47/47 ,  C07C49/21 ,  C07C49/242 ,  C07C49/258 ,  C07C49/583 ,  C07C49/733 ,  C07C49/757 ,  C07D303/04 ,  Y02A40/166

摘要： Compounds, compositions, and methods for controlling an arthropod pest population that employ an eremophilane sesquiterpene parent structure are presented. The compounds have minimal adverse or toxic effects on humans, non-human animals, and the natural environment. The compounds may be isolated from natural sources, semi-synthesized from naturally occurring compounds, or completely synthesized. The compounds may be applied directly to a pest, or the locus of a pest, and function as topical or ingestible toxins. Eremophilane sesquiterpenes 13-hydroxy-valencene, valencene-11,12-epoxide, valencene-13-aldehyde, and nootkatone-1,10-11,12-diepoxide are exemplary compounds.

公开(公告)号：EP2747886B1

公开(公告)日：2018-11-14

申请号：EP12766450.6

申请日：2012-09-27

申请人： Firmenich SA

发明人： DUPAU, Philippe ,  BONOMO, Lucia ,  KERMORVAN, Laurent

IPC分类号： B01J31/18 ,  B01J31/24 ,  B01J31/22 ,  C07B41/02 ,  C07C29/141 ,  C07C67/00 ,  C07C29/145

CPC分类号： C07C29/141 ,  B01J31/1805 ,  B01J31/181 ,  B01J31/2226 ,  B01J31/24 ,  B01J31/2409 ,  B01J2231/643 ,  B01J2531/0238 ,  B01J2531/821 ,  C07B41/02 ,  C07B2200/07 ,  C07C29/145 ,  C07C45/64 ,  C07C67/00 ,  C07C2601/02 ,  C07C2601/04 ,  C07C2601/10 ,  C07C2601/16 ,  C07C2601/18 ,  C07C2602/42 ,  C07C33/12 ,  C07C49/17 ,  C07C49/172 ,  C07C49/573 ,  C07C33/025 ,  C07C69/145 ,  C07C33/30 ,  C07C33/03 ,  C07C69/24 ,  C07C69/78 ,  C07C49/337 ,  C07C49/242

摘要： The present invention relates to processes for the reduction by hydrogenation, using molecular H2, of a C5-C20 substrate containing one or two aldehydes functional groups into the corresponding alcohol or diol, characterized in that said process is carried out in the presence of —at least one catalyst or pre-catalyst in the form of a ruthenium complex having a coordination sphere of the N2P2O2, wherein the coordinating atoms N2 are provided by a first bidentate ligand, the coordinating atoms P2 are provided by a second bidentate ligand and the coordinating atoms O2 are provided by two non-linear carboxylate ligands; and—optionally of an acidic additive.

公开(公告)号：EP0260551A3

公开(公告)日：1989-12-27

申请号：EP87112977.1

申请日：1987-09-04

申请人： F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft

发明人： Fischli, Albert, Prof. Dr. ,  Schmid, Max, Dr. ,  Schmid, Rudolf, Dr.

IPC分类号： C07C49/24 ,  C07C49/258 ,  C07C47/263 ,  C07C43/178 ,  C07C59/76 ,  C07C33/035 ,  C07D317/20 ,  C07C103/133 ,  C07C131/00 ,  C07F7/08

CPC分类号： C07F7/1852 ,  C07C33/02 ,  C07C33/035 ,  C07C33/12 ,  C07C43/178 ,  C07C43/315 ,  C07C45/298 ,  C07C45/673 ,  C07C47/263 ,  C07C49/24 ,  C07C49/242 ,  C07C49/255 ,  C07C49/258 ,  C07C59/42 ,  C07C59/76 ,  C07C323/00 ,  C07C323/24 ,  C07D317/20

摘要： Verbindungen der Formel
und die punktierten Linien fakultative zusätzliche C-C-­Bindungen mit E- oder Z-Konfiguration bedeuten und die übrigen Symbole die in Anspruch 1 angegebene Bedeutung besitzen,
sowie pharmazeutisch verwendbare Salze davon haben mucosa-­protektive und magensäuresekretionshemmende Eigenschaften und können zur Behandlung von Ulcus ventriculi und/oder duodeni verwendet werden. Sie sind neu, mit Ausnahme von 10-Hydroxy-3,7,11-trimethyl-2,6,11-dodecatriensäure und 3,7,11-Trimethyl-2,6,11-dodecatrien-1,10-diol. Sie können zu galenischen Darreichungsformen verarbeitet und nach ver­schiedenen Verfahren hergestellt werden.

摘要翻译： 具有粘膜保护性和胃酸分泌抑制性质的新型异戊二烯衍生物，可用于通过治疗和预防胃和/或十二指肠溃疡来对抗溃疡。

公开(公告)号：EP0195053A1

公开(公告)日：1986-09-24

申请号：EP85904773.0

申请日：1985-09-26

申请人： CHEVRON RESEARCH AND TECHNOLOGY COMPANY

发明人： CLEVELAND, James, D.

IPC分类号： C07C69 ,  B01J31 ,  C07B35 ,  C07B61 ,  C07C45 ,  C07C49 ,  C07C67 ,  C07C201 ,  C07C205 ,  C07C253 ,  C07C255 ,  C07C313 ,  C07C317 ,  C07C319 ,  C07C323

CPC分类号： C07C403/16 ,  C07C45/455 ,  C07C45/66 ,  C07C45/72 ,  C07C45/74 ,  C07C201/12 ,  C07C319/20 ,  C07C2601/08 ,  C07C2601/14 ,  C07D309/06 ,  C07D319/06 ,  C07D333/22 ,  C07D339/08 ,  C07C323/22 ,  C07C205/45 ,  C07C49/203 ,  C07C49/21 ,  C07C49/217 ,  C07C49/235 ,  C07C49/255 ,  C07C49/242 ,  C07C49/248

摘要： Procédé de préparation de cétones insaturées alpha, bêta et de dérivés de 1,3-cyclohexanedione. Les dérivés de 1,3-cyclohexanedione sont utiles comme intermédiares pour des pesticides, spécialement des herbicides.

摘要翻译： 用于制备α，β-不饱和酮和1,3-环己二酮衍生物。 作为农药中间体爱特别除草剂的1.3环己二酮衍生物是有用的。

公开(公告)号：EP3322294A1

公开(公告)日：2018-05-23

申请号：EP16801287.0

申请日：2016-06-28

申请人： King Abdullah University of Science and Technology

发明人： AL-BABILI, Salim

IPC分类号： A01N49/00 ,  A01P21/00

CPC分类号： A01N35/02 ,  A01N37/42 ,  A01N49/00 ,  C07C49/242 ,  C07C59/90 ,  C07C62/38 ,  C07C2601/16

摘要： New plant growth regulators, including compounds and compositions, and methods of use including for promoting root growth. The compounds are carotenoid oxidation products, and a preferred example is 3-OH-β-apo-13-Carotenone. A method comprising promoting the growth of at least one plant with use of an effective amount of at least one composition comprising an effective amount of at least one compound which is represented by A-B-C, wherein B is a bivalent polyene moiety, A is a monovalent moiety linked to B by a six-membered carbon ring, wherein the ring has at least one substituent linked to the ring by an oxygen atom, and C is a monovalent moiety linked to B by a carbonyl group. Synergistic effects can be used with combinations of compounds.

公开(公告)号：EP2094634A2

公开(公告)日：2009-09-02

申请号：EP07838896.4

申请日：2007-09-25

申请人： Millennium Specialty Chemicals, Inc.

发明人： KOLOMEYER, Gennadiy G. ,  OYLOE, Jacob ,  FERONE, Douglas A.

IPC分类号： C07C45/66 ,  C07C45/72 ,  C07C45/74 ,  C07C45/82 ,  C07C49/21 ,  C07C49/242

CPC分类号： C07C45/66 ,  C07C45/72 ,  C07C45/74 ,  C07C45/82 ,  C07C49/21 ,  C07C49/242

摘要： A two-step aldol condensation process is disclosed. α-Campholenic aldehyde (ACA) and methyl ethyl ketone (MEK) react in the presence of a base under conditions effective to produce a mixture comprising a high yield of ketol condensation products. Dehydration of the ketols in the presence of an organic sulfonic acid provides unsaturated ketones that are valuable intermediates for fragrance components for synthetic sandalwood products. Compared with the usual one-step, base-catalyzed approach, the two-step process increases the yield of all condensation products and maximizes production of the most valuable ketone isomers.

公开(公告)号：EP0972762A3

公开(公告)日：2000-02-23

申请号：EP99203513.9

申请日：1994-07-07

申请人： LABORATOIRE THERAMEX

发明人： The designation of the inventor has not yet been filed

IPC分类号： C07C401/00 ,  A61K31/59 ,  C07C49/523 ,  C07C35/27 ,  C07C47/347 ,  C07C69/757

CPC分类号： C07C47/198 ,  C07C35/22 ,  C07C35/27 ,  C07C47/192 ,  C07C47/36 ,  C07C47/37 ,  C07C49/242 ,  C07C49/517 ,  C07C49/687 ,  C07C49/743 ,  C07C49/755 ,  C07C57/26 ,  C07C59/01 ,  C07C401/00

摘要： The present invention relates to analogues of vitamin D, which lack the combined presence of the trans-fused six-membered C-ring and of five-membered D-ring, but still possess a central part consisting of a substituted chain of five atoms, atoms which correspond to positions 8, 14, 13, 17 and 20 of vitamin D, and at the ends of which are connected, at position 20 a structural moiety representing part of the side-chain of vitamin D or of an analogue of vitamin D, and at position 8 the Δ(5,7)-diene moiety connected to the A-ring of the active 1-alpha-hydroxy metabolite or of an established vitamin D analogue, to their preparation process, to pharmaceutical preparations comprising these compounds and to their use in medicine.

公开(公告)号：EP0195053B1

公开(公告)日：1992-02-12

申请号：EP85904773.0

申请日：1985-09-26

申请人： CHEVRON RESEARCH AND TECHNOLOGY COMPANY

发明人： CLEVELAND, James, D.

IPC分类号： C07C45/72 ,  C07C45/66 ,  C07C49/00 ,  C07C321/12

CPC分类号： C07C403/16 ,  C07C45/455 ,  C07C45/66 ,  C07C45/72 ,  C07C45/74 ,  C07C201/12 ,  C07C319/20 ,  C07C2601/08 ,  C07C2601/14 ,  C07D309/06 ,  C07D319/06 ,  C07D333/22 ,  C07D339/08 ,  C07C323/22 ,  C07C205/45 ,  C07C49/203 ,  C07C49/21 ,  C07C49/217 ,  C07C49/235 ,  C07C49/255 ,  C07C49/242 ,  C07C49/248

摘要： Process for preparing alpha, beta-unsaturated ketones and 1,3-cyclohexanedione derivatives. The 1,3-cyclohexanedione derivatives are useful as intermediates for pesticides especially herbicides.

摘要翻译： 制备α，β-不饱和酮和1,3-环己二酮衍生物的方法。 1,3-环己二酮衍生物可用作农药，特别是除草剂的中间体。

公开(公告)号：EP0260551A2

公开(公告)日：1988-03-23

申请号：EP87112977.1

申请日：1987-09-04

申请人： F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft

发明人： Fischli, Albert, Prof. Dr. ,  Schmid, Max, Dr. ,  Schmid, Rudolf, Dr.

IPC分类号： C07C49/24 ,  C07C49/258 ,  C07C47/263 ,  C07C43/178 ,  C07C59/76 ,  C07C33/035 ,  C07D317/20 ,  C07C103/133 ,  C07C131/00 ,  C07F7/08

CPC分类号： C07F7/1852 ,  C07C33/02 ,  C07C33/035 ,  C07C33/12 ,  C07C43/178 ,  C07C43/315 ,  C07C45/298 ,  C07C45/673 ,  C07C47/263 ,  C07C49/24 ,  C07C49/242 ,  C07C49/255 ,  C07C49/258 ,  C07C59/42 ,  C07C59/76 ,  C07C323/00 ,  C07C323/24 ,  C07D317/20

摘要： Verbindungen der Formel
und die punktierten Linien fakultative zusätzliche C-C-­Bindungen mit E- oder Z-Konfiguration bedeuten und die übrigen Symbole die in Anspruch 1 angegebene Bedeutung besitzen,
sowie pharmazeutisch verwendbare Salze davon haben mucosa-­protektive und magensäuresekretionshemmende Eigenschaften und können zur Behandlung von Ulcus ventriculi und/oder duodeni verwendet werden. Sie sind neu, mit Ausnahme von 10-Hydroxy-3,7,11-trimethyl-2,6,11-dodecatriensäure und 3,7,11-Trimethyl-2,6,11-dodecatrien-1,10-diol. Sie können zu galenischen Darreichungsformen verarbeitet und nach ver­schiedenen Verfahren hergestellt werden.

摘要翻译： 具有粘膜保护性和胃酸分泌抑制性质的新型异戊二烯衍生物，可用于通过治疗和预防胃和/或十二指肠溃疡来对抗溃疡。