公开(公告)号：EP2561362B1

公开(公告)日：2018-09-12

申请号：EP11731241.3

申请日：2011-04-14

Applicant: Bioserv Analytik und Medizinprodukte GmbH

Inventor： MEYER, Udo ,  STEINMANN, Alain ,  FAHLANDT, Heike ,  SCHULZ, Babette

IPC: G01N33/569

CPC classification number: C07K16/1235 ,  C07K2317/34 ,  C12Q1/689 ,  G01N33/56916 ,  G01N2333/255 ,  Y02A50/451

公开(公告)号：EP2831577B1

公开(公告)日：2018-08-08

申请号：EP13768340.5

申请日：2013-03-28

Applicant: Purdue Research Foundation

Inventor： LADISCH, Michael, R. ,  XIMENES, Eduardo

IPC: G01N33/00 ,  B01D63/02 ,  G01N33/569 ,  C12Q1/24

CPC classification number: G01N33/56916 ,  B01D63/02 ,  B01D65/022 ,  B01D65/06 ,  B01D2321/164 ,  B01D2321/168 ,  C12Q1/22 ,  C12Q1/24 ,  G01N1/4077 ,  G01N33/56911 ,  G01N2001/4088 ,  G01N2333/245 ,  G01N2333/255

Abstract: Described are methods and systems useful in the processing of food samples to detect pathogenic cells in the samples. Embodiments include homogenizing a food sample, digesting solids of the homogenized food sample, and removing lipids from the homogenized food sample. Cells in the sample can then be concentrated using hollow fiber membrane filtration. Regeneration cycles can enable multiple reuses of the hollow fiber membrane filter. Systems and processes herein can be automated, under the control of a computer.

公开(公告)号：EP3011062A4

公开(公告)日：2017-06-14

申请号：EP14813675

申请日：2014-06-19

Applicant: SAMPLE6 TECH INC

Inventor： KOERIS MICHAEL SANDOR ,  THOMASON JULIE ,  CAPPILLINO MICHAEL ,  SHIVERS ROBERT PATRICK ,  BROWNELL DANIEL ROBERT ,  BOWERS JAYSON L ,  LU TIMOTHY KUAN TA ,  KRZYMANSKA-OLEJNIK EDYTA

IPC: C12Q1/70

CPC classification number: C12Q1/66 ,  C12N7/00 ,  C12Q1/10 ,  G01N33/82 ,  G01N2333/245 ,  G01N2333/255

Abstract: Methods of detecting target bacteria are provided. In some embodiments the methods comprise exposing the sample to a phage capable of infecting a set of target bacteria and comprising a heterologous nucleic acid sequence encoding a marker. In some embodiments the target bacteria comprise Listeria. In some embodiments the target bacteria are all Listeria. Recombinant Listeria phage comprising a heterologous nucleic acid sequence encoding a marker are also provided as are useful combinations of such phage and articles of manufacture comprising such phage, among other things.

Abstract translation: 提供了检测靶细菌的方法。 在一些实施方案中，所述方法包括将样品暴露于能够感染一组靶细菌并且包含编码标记的异源核酸序列的噬菌体。 在一些实施方案中，靶细菌包含李斯特菌。 在一些实施方案中，目标细菌全部是李斯特氏菌。 还提供了包含编码标记物的异源核酸序列的重组利斯特氏菌噬菌体，以及此类噬菌体和包含此类噬菌体的制品等的有用组合。

公开(公告)号：EP3145946A1

公开(公告)日：2017-03-29

申请号：EP15725282.6

申请日：2015-05-20

Applicant: Universität Basel

Inventor： ARRIEUMERLOU, Cécile ,  ITTIG, Simon

IPC: C07K14/195 ,  C12N15/70 ,  C12N15/74

CPC classification number: C12N15/74 ,  A61K48/00 ,  C07K14/195 ,  C07K14/24 ,  C07K2319/035 ,  C07K2319/50 ,  C12N15/70 ,  C12Q1/025 ,  G01N2333/24 ,  G01N2333/245 ,  G01N2333/255 ,  G01N2500/10

Abstract: The present invention relates to recombinant Gram-negative bacterial strains and the use thereof for delivery of heterologous proteins into eukaryotic cells.

Abstract translation: 本发明涉及重组革兰氏阴性细菌菌株及其将异源蛋白质递送到真核细胞中的用途。

公开(公告)号：EP2670858B1

公开(公告)日：2014-11-05

申请号：EP12707829.3

申请日：2012-01-31

Applicant: Biomérieux

Inventor： ROCHE, Jean-Marc

IPC: C12Q1/04

CPC classification number: C12Q1/04 ,  C12Q1/045 ,  G01N2333/255

公开(公告)号：EP2668501A2

公开(公告)日：2013-12-04

申请号：EP12739759.4

申请日：2012-01-27

Applicant: Invisible Sentinel, Inc.

Inventor： SICILIANO, Nicholas, A. ,  BOULIANE, Martin, Joseph ,  LEONG, Louis

IPC: G01N33/543

CPC classification number: G01N33/02 ,  B01L3/5023 ,  B01L3/502738 ,  B01L2300/0816 ,  B01L2300/0832 ,  B01L2300/0864 ,  B01L2300/0874 ,  B01L2300/123 ,  B01L2400/0406 ,  B01L2400/0487 ,  B01L2400/0633 ,  B01L2400/0694 ,  G01N33/558 ,  G01N33/56916 ,  G01N33/56922 ,  G01N2333/205 ,  G01N2333/245 ,  G01N2333/255

Abstract: Devices and methods for the detection of analytes are disclosed. Devices and methods for detecting food-borne pathogens are disclosed.

Abstract translation: 用于检测分析物的装置和方法游离缺失盘。 为了检测食源性致病菌的装置和方法游离缺失盘。

公开(公告)号：EP2633082A2

公开(公告)日：2013-09-04

申请号：EP11837012.1

申请日：2011-10-26

Applicant: The Government of the United States of America as Represented by the Secretary of the Department of Health and Human Services

Inventor： FIELDS, Patricia ,  MCQUISTON, John, R. ,  FITZGERALD LEAUMONT, Collette

IPC: C12Q1/68 ,  C12Q1/04 ,  C12N15/11

CPC classification number: C12Q1/689 ,  C12Q2600/158 ,  C12Q2600/16 ,  G01N2333/255 ,  Y02A50/451

Abstract: Processes for the serotype specific detection and identification of one or more Salmonella serotypes are provided. A family of specific primers and probes are provided that allow screening of biological or environmental samples for robust, rapid, and reproducible detection and identification of one or more Salmonella serotypes in the sample.

Abstract translation: 提供了血清型特异性检测和鉴定一种或多种沙门氏菌血清型的方法。 提供了一系列特异性引物和探针，其允许筛选生物或环境样品以便对样品中的一种或多种沙门氏菌血清型进行稳健，快速和可重现的检测和鉴定。

公开(公告)号：EP2521917A4

公开(公告)日：2013-07-10

申请号：EP11732217

申请日：2011-01-07

Applicant: PHARMACO KINESIS CORP ,  WU WINSTON ,  CHEN THOMAS ,  FARKAS LESLIE ,  JORDAN BRETT ,  LUBOFF PALADIN ,  CHAN HERWIN ,  ZIMMERMAN KYLE ,  SHACHAR YEHOSHUA

Inventor： SHACHAR YEHOSHUA ,  WU WINSTON ,  CHEN THOMAS ,  FARKAS LESLIE ,  JORDAN BRETT ,  LUBOFF PALADIN ,  CHAN HERWIN ,  ZIMMERMAN KYLE

IPC: G01N33/53 ,  C12Q1/10 ,  G01N27/26 ,  G01N29/24 ,  G01N33/569 ,  G01N33/68

CPC classification number: G01N33/5308 ,  G01N33/5438 ,  G01N33/56916 ,  G01N2333/255

Abstract: An aptamer-based solid-state electrochemical biosensor for label-free detection of Salmonella enterica serovars utilizing immobilized aptamers. The device is realized by forming a matrix array of parallel capacitors, thus allowing the realization of low-cost, portable, fully integrated devices. Protein-aptamer binding modulates the threshold voltage of a circuit, changing the impedance (capacitance) of the circuit. This circuit is further characterized by an electrode coded with a p-Si substrate, enhancing the affinity between the Salmonella outer membrane proteins (OMPs) and the aptamer. An aptamer embedded detection plate is configured within a testing lid device that fits a standard, commercially available polymer specimen jar. A sample is mixed with broth for incubation and cultivation of any present Salmonella bacteria to obtain acceptable concentration of the pathogen for testing. The information obtained can then be transmitted by wireless network.

Abstract translation: 一种基于适配子的固态电化学生物传感器，用于利用固定化适配子无标记检测肠道沙门氏菌血清型。 该器件通过形成并联电容器的矩阵阵列来实现，从而允许实现低成本，便携式，完全集成的器件。 蛋白质 - 适体结合调节电路的阈值电压，改变电路的阻抗（电容）。 该电路的特征还在于用p-Si底物编码的电极，增强了沙门氏菌外膜蛋白（OMP）和适体之间的亲和力。 适配器嵌入的检测板配置在测试盖装置内，该装置适合标准的市售聚合物标本罐。 将样品与肉汤混合以培养和培养任何现有的沙门氏菌以获得可接受浓度的用于测试的病原体。 所获得的信息可以通过无线网络传输。

公开(公告)号：EP2486120A4

公开(公告)日：2013-04-03

申请号：EP10822833

申请日：2010-10-12

Applicant: INVISIBLE SENTINEL INC

Inventor： SICILIANO NICHOLAS A ,  BOULIANE MARTIN JOSEPH

IPC: C12M1/34 ,  C12Q1/04 ,  G01N33/53 ,  G01N33/543

CPC classification number: G01N33/54386 ,  C12Q1/04 ,  G01N33/5302 ,  G01N2333/205 ,  G01N2333/245 ,  G01N2333/255

Abstract: Devices and methods for the detection of antigens are disclosed. Devices and methods for detecting food-borne pathogens are disclosed.

公开(公告)号：EP1931796B9

公开(公告)日：2011-06-08

申请号：EP06793015.6

申请日：2006-08-25

Applicant: Rambach, Alain

Inventor： Rambach, Alain

IPC: C12Q1/04

CPC classification number: C12Q1/045 ,  C12N1/20 ,  G01N2333/255 ,  Y02A50/451

Abstract: The invention relates to a medium for the detection and/or identification of Salmonella, including Salmonella lactose+.