NOVEL MERCAPTANS AND DISULFIDES
    3.
    发明公开
    NOVEL MERCAPTANS AND DISULFIDES 有权
    MERCAPTANE UND DISIFFIDE

    公开(公告)号:EP1109779A4

    公开(公告)日:2003-04-16

    申请号:EP99948083

    申请日:1999-08-30

    CPC分类号: C07C323/66 C07F9/3808

    摘要: This invention relates to novel compositions of matter which either terminate in a sulfhydryl moiety or are disulfides. The compounds also include a terminal sulfonate or phosphonate moiety, and have many uses, such as toxicity reducing agents when administered with many antineoplastic agents.

    摘要翻译: 本发明涉及终止于巯基部分或二硫化物的物质的新组合物。 化合物还包括末端磺酸盐或膦酸盐部分,并且当与许多抗肿瘤剂一起施用时具有许多用途,例如毒性降低剂。

    New metal ion control agents based on dicyclopentadiene derivatives
    9.
    发明公开
    New metal ion control agents based on dicyclopentadiene derivatives 失效
    螯合基于双环戊二烯衍生物的药物。

    公开(公告)号:EP0166020A1

    公开(公告)日:1986-01-02

    申请号:EP84107526.0

    申请日:1984-06-29

    发明人: Wilson, David A.

    CPC分类号: C07F9/3817 C02F5/12 C02F5/14

    摘要: New compounds have been prepared from dicyclopentadiene bis(methylamine) which have the following formula

    wherein substituents A, B, X and Y each are independently selected from radicals comprising hydrogen, C 2 to C 6 hydroxyalkyl; hydroxyethyl- and hydroxypropylsulfonic; meth- yienephosphonic; methylene-, ethylene- and propylenesul- fonic, C 2 to C 4 alkylcarboxylic acid radicals; and the alkali metal, alkaline earth metal, ammonia, and amine salts of the foregoing acids; and wherein at least one of A, B, X, and Y is other than hydrogen. These compounds are useful as ion control (chelating) agents in aqueous solutions. In a preferred embodiment, the compounds have threshhold (less than stochiometric amounts required) activity.

    Preparation of halogenated phenols
    10.
    发明公开
    Preparation of halogenated phenols 失效
    卤代酚的制备。

    公开(公告)号:EP0146923A1

    公开(公告)日:1985-07-03

    申请号:EP84115842.1

    申请日:1984-12-19

    申请人: FIDIA S.p.A.

    摘要: A method for the preparation of 2-halogenoresorcinols having the following formula I
    where X represents a halogen atom and R and R, may be the same or different and represent a hydrogen atom or a free organic functional or functionally modified group or a hydrocarbon group, which may be substituted by one or more free organic functional or functionally modified groups and R and R, jointly may also represent a free organic functional or functionally modified group or a hydrocarbon group-which may be substituted by one or more free organic functional or functionally modified groups, and esters, ethers, or salts thereof.
    The method comprises sulfonating the corresponding resorcinols which do not contain a halogen in position-2 and then halogenating the sulfonic acids thus obtained. The halogenated sulfonic acids thereby obtained are subsequently protodesulfonated by acid hydrolysis and, if desired, any functional groups which may be present can be modified.