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公开(公告)号：EP4451857A1
公开(公告)日：2024-10-30
申请号：EP22908878.6
申请日：2022-12-19
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公开(公告)号：EP4440548A1
公开(公告)日：2024-10-09
申请号：EP22826212.7
申请日：2022-12-01
IPC分类号： A61K9/08 , A61K31/192 , A61K31/198 , A61K47/02
CPC分类号： A61K9/0078 , A61K9/08 , A61K31/198 , A61K47/02
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公开(公告)号：EP4434358A1
公开(公告)日：2024-09-25
申请号：EP22895594.4
申请日：2022-11-15
发明人： IWASAKI Yusaku
IPC分类号： A23L33/10 , A23L33/105 , A23L33/12 , A61K31/122 , A61K31/192 , A61K31/201 , A61P1/14 , A61P25/02 , A61P43/00 , C07C50/16 , C07C66/02
CPC分类号： A23L33/10 , A23L33/105 , A23L33/12 , A61K31/122 , A61K31/201 , A61K31/192 , A61P1/14 , A61P25/02 , A61P43/00 , C07C50/16 , C07C66/02
摘要： The purpose of the present invention is to newly discover a transient receptor potential ankyrin 1 (TRPA1) agonist that exhibits an action for increasing the amount of food ingested, to provide a novel agonist of TRPA1, or to provide a novel active ingredient that exhibits an action for increasing the amount of food ingested or an action for improving anorexia. A compound having a specific fatty acid or a specific anthraquinone structure has an effect for activating TRPA1 and can be used as an active ingredient for increasing the amount of food ingested and/or improving anorexia.
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公开(公告)号：EP3435993B1
公开(公告)日：2024-09-25
申请号：EP17716149.4
申请日：2017-04-03
IPC分类号： A61K31/16 , A61P27/00 , A61P29/00 , A61K31/165 , A61K31/19 , A61K31/192 , A61K31/22 , A61K31/341 , A61K31/351 , A61K31/40 , A61K31/41 , A61K31/4196 , A61K31/421 , A61K31/5375
CPC分类号： A61K31/16 , A61K31/165 , A61K31/19 , A61K31/192 , A61K31/22 , A61K31/341 , A61K31/351 , A61K31/40 , A61K31/41 , A61K31/4196 , A61K31/421 , A61K31/5375 , A61P27/00 , A61P29/00
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公开(公告)号：EP4422609A1
公开(公告)日：2024-09-04
申请号：EP22800991.6
申请日：2022-10-26
IPC分类号： A61K31/05 , A61K31/192 , A61K31/337 , A61K31/555 , A61K36/185 , A61P35/00
CPC分类号： A61K36/185 , A61P35/00 , A61K31/337 , A61K31/555 , A61K45/06 , A61K31/658
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公开(公告)号：EP3452032B1
公开(公告)日：2024-09-04
申请号：EP17719772.0
申请日：2017-04-07
IPC分类号： A61K31/192 , A61K31/167 , A61K31/232 , A61K31/235 , A61K31/25 , A61K31/353 , A61K31/40 , A61K31/4025 , A61K31/4155 , A61K31/426 , A61K31/44 , A61K31/4436 , A61K31/498 , A61K31/519 , A61K31/5377 , A61K31/55 , A61K31/551 , A61K31/553 , A61K31/573 , A61K31/69 , A61K31/695 , A61K33/24 , A61K33/36 , A61K45/06 , G01N33/48 , A61P35/00 , A61P35/02 , A61P35/04 , A61P43/00
CPC分类号： A61K45/06 , A61K31/167 , A61K31/192 , A61K31/232 , A61K31/235 , A61K31/25 , A61K31/353 , A61K31/40 , A61K31/4025 , A61K31/4155 , A61K31/426 , A61K31/44 , A61K31/4436 , A61K31/498 , A61K31/519 , A61K31/5377 , A61K31/55 , A61K31/551 , A61K31/553 , A61K31/573 , A61K31/69 , A61K31/695 , A61K31/704 , A61K31/706 , A61K31/7068 , A61K33/24 , A61K33/36 , G01N33/48 , A61P35/00 , A61P35/02 , A61P35/04 , A61P43/00
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7.发明公开
公开(公告)号：EP4415739A1
公开(公告)日：2024-08-21
申请号：EP22879680.1
申请日：2022-10-11
发明人： CRIPPS, Allan William , ISIKGEL, Esra , ANDREWS, Alexandra Elizabeth Marion , DUTHY, Thomas George
IPC分类号： A61K36/185 , A61K31/05 , A61K31/192 , A61K31/196 , A61K31/635 , A61K31/661 , A61P25/16 , A61P25/28
CPC分类号： A61K36/185 , A61P25/28 , A61P25/16 , A61K2236/0020130101 , A61K31/685 , A61K31/573 , A61K31/196
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8.发明公开
公开(公告)号：EP4374861A3
公开(公告)日：2024-08-07
申请号：EP23203862.0
申请日：2016-11-16
申请人： MedinCell S.A.
IPC分类号： A61K9/00 , A61K47/34 , A61K9/08 , A61K31/415 , A61P19/02 , A61K31/12 , A61K31/165 , A61K31/167 , A61K31/18 , A61K31/192 , A61K31/365 , A61K31/196 , A61K31/42 , A61K31/444 , A61K31/445 , A61K31/5415 , A61K31/621 , A61P3/02
CPC分类号： A61K9/0019 , A61K9/0024 , A61K47/34 , A61K9/08 , A61K31/196 , A61K31/445 , A61K31/365 , A61K31/12 , A61K31/621 , A61K31/444 , A61K31/5415 , A61K31/4152 , A61K31/42 , A61K31/167 , A61K31/165 , A61K31/18 , A61K31/192
摘要： A method of targeting to the synovial tissue biodegradable drug delivery compositions or morselizing biodegradable drug delivery compositions are described. The biodegradable drug composition comprises a triblock copolymer containing a polyester and a polyethylene glycol and a diblock copolymer containing a polyester and an end-capped polyethylene glycol, as well as at least one pharmaceutically active principle is disclosed.
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公开(公告)号：EP4406937A1
公开(公告)日：2024-07-31
申请号：EP22871956.3
申请日：2022-09-20
发明人： XIA, Hongguang , FAN, Mengyang , CEN, Xufeng , XU, Xiaoyan , WU, Ronghai , LIU, Dong , TIAN, Zhen
IPC分类号： C07C323/52 , C07C381/10 , C07D305/08 , C07D285/10 , C07D285/16 , C07D249/08 , C07D257/04 , C07D333/34 , A61K31/192 , A61K31/337 , A61K31/381 , A61K31/265 , A61K31/222 , A61K31/4196 , A61K31/41 , A61K31/549 , A61K31/433 , A61P43/00
CPC分类号： A61K31/222 , A61K31/192 , A61K31/337 , A61K31/265 , A61K31/381 , A61K31/41 , A61K31/433 , A61K31/4196 , A61K31/549 , A61P43/00 , C07C323/52 , C07C381/10 , C07D249/08 , C07D257/04 , C07D285/10 , C07D285/16 , C07D305/08 , C07D333/34
摘要： The present application discloses a small-molecule compound having a naphthalenethiol ether structure, and a use thereof. Disclosed in the present application are a compound having a structure represented by general formula (I), a pharmaceutically acceptable salt, a stereoisomer, a solvate or a prodrug thereof, a pharmaceutical composition containing the same, and a use thereof in the preparation of mitophagy inducer drugs. In the present application, the structure of the compound having the structure represented by general formula (I) is shown below. The compound and the pharmaceutically acceptable salt, stereoisomer, solvate or prodrug thereof, or the pharmaceutical composition provided in the present application can enhance the ability to induce mitophagy.
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公开(公告)号：EP3570825B1
公开(公告)日：2024-07-31
申请号：EP18741911.4
申请日：2018-01-09
IPC分类号： A61K31/122 , A61K31/192 , A61K31/196 , A61K31/216 , A61K31/222 , A61K31/606 , A61P1/00 , A61P1/06
CPC分类号： A61K31/216 , A61P1/00 , A61K31/196 , A61K31/122 , A61K31/222 , A61K31/192 , A61K31/606 , A61P1/06
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