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1.发明公开
公开(公告)号：EP4328223A3
公开(公告)日：2024-11-06
申请号：EP23205984.0
申请日：2012-04-20
发明人： BENNETT, Brydon , ELSNER, Jan , ERDMAN, Paul , HILGRAF, Robert , LEBRUN, Laurie Ann , MCCARRICK, Meg , MOGHADDAM, Mehran , NAGY, Mark A. , NORRIS, Stephen , PAISNER, David A. , SLOSS, Marianne , ROMANOW, William J. , SATOH, Yoshitaka , TIKHE, Jayashree , YOON, Won Hyung , DELGADO, Maria Mercedes
IPC分类号： C07D239/48 , C07D405/02 , C07D401/12 , C07D409/12
摘要： Provided herein is a compound of formula (I)
or a pharmaceutically acceptable salt, tautomer, stereoisomer, enantiomer, isotopologue, or prodrug thereof, wherein R 1 and R 2 are as defined herein. Also provided are methods and reaction intermediates for preparing said compound.-
公开(公告)号：EP3654395B9
公开(公告)日：2024-11-06
申请号：EP18831305.0
申请日：2018-07-11
发明人： CHA, Soon-Wook , PARK, Sang-Woo , YOO, Jung-Ho , SHIN, Yoona , LEE, Yu-Rim , KIM, Sung Woo , LEE, Jiwon
IPC分类号： H10K85/60 , C07D307/94 , C07D209/96 , C07D333/50 , C07D405/04 , C07D405/14 , C07D407/14 , C07D409/12 , C07D409/14 , C07D491/048 , C07D491/10 , C07D491/153 , C07D491/20 , C07D493/04 , C07D493/10 , C07D493/20 , C07D493/22 , C07D495/04 , C07D495/10 , C07D519/00 , H10K50/15
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公开(公告)号：EP3710430B9
公开(公告)日：2024-10-30
申请号：EP18877721.3
申请日：2018-11-15
IPC分类号： C07D231/08 , C07D401/12 , C07D403/12 , C07D405/12 , C07D409/12 , C07D413/12 , A61K31/4152 , A61K31/4155 , A61P35/00 , A61P3/00 , A61P25/00 , A61P29/00 , A61P31/12 , A61P37/02
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公开(公告)号：EP4192812B1
公开(公告)日：2024-09-04
申请号：EP22741485.1
申请日：2022-06-30
IPC分类号： C07D213/75 , C07D213/81 , C07D401/12 , C07D405/12 , C07D409/12 , C07D413/12 , C07D417/12 , C07D453/02 , C07D513/04 , A61K31/443 , A61P37/02 , C07D471/04 , C07D487/08
CPC分类号： C07D213/75 , C07D213/81 , C07D401/12 , C07D405/12 , C07D409/12 , C07D413/12 , C07D417/12 , C07D453/02 , C07D513/04 , C07D471/04 , C07D487/08 , Y02A50/30
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公开(公告)号：EP4408530A1
公开(公告)日：2024-08-07
申请号：EP22790423.2
申请日：2022-09-26
发明人： DECKHUT, Charlotte, Pooley , BEHENNA, Douglas, C. , BEMBENEK, Scott , GOLDBERG, Steven, D. , JACKSON, Paul, F. , KEITH, John , LOSKOT, Steven, A. , MARTIN, Connor , MCCARVER, Stefan , MEDUNA, Steven, P. , RHORER, Timothy, B. , SHIH, Amy, Y. , TANIS, Virginia, M. , WOODS, Craig, R. , XUE, Xiaohua
IPC分类号： A61P17/06 , A61P19/02 , A61P29/00 , C07D235/14 , C07D403/12 , C07D405/14 , C07D409/12 , C07D413/12 , C07D413/14 , C07D417/12 , C07D487/04 , A61K31/4184 , A61K31/4192 , A61K31/4196 , A61K31/4245
CPC分类号： C07D413/12 , C07D403/12 , C07D405/14 , C07D413/14 , C07D417/12 , C07D409/12 , C07D487/04 , C07D235/14 , A61P29/00 , A61P19/02 , A61P17/06
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6.发明公开
公开(公告)号：EP4403551A1
公开(公告)日：2024-07-24
申请号：EP22870127.2
申请日：2022-07-22
发明人： HAM, Ho Wan , AN, Hyun Cheol , MIN, Byung Cheol , KIM, Hee Joo , LEE, Dong Hyun , ANN, Ja Eun , KWON, Dong Yuel , KIM, Tae Min , IM, Hyeon Jeong , OH, Il Soo , PARK, Yeong Rong , LEE, Dae Woong , LEE, Bo Ra , CHO, Ill Hun
IPC分类号： C07D295/104 , C07D401/12 , C07D407/12 , C07D409/12 , C07D417/12 , C07D413/12 , C07D471/04 , C07D237/04 , C07D239/04 , C07D243/08
CPC分类号： C07D413/12 , C07D401/12 , C07D237/04 , C07D239/04 , C07D295/104 , C07D407/12 , C07D471/04 , C07D243/08 , C07D409/12 , C07D417/12
摘要： A novel compound for a light emitting device, and an organic light emitting device containing the same are disclosed.
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公开(公告)号：EP3632910B1
公开(公告)日：2024-07-17
申请号：EP18806569.2
申请日：2018-05-25
IPC分类号： C07D413/14 , C07D417/14 , C07D401/12 , C07D409/12 , C07D413/12 , A61P1/16
CPC分类号： C07D413/14 , C07D417/14 , C07D413/12 , C07D409/12 , C07D401/12 , A61P1/16
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公开(公告)号：EP4384513A1
公开(公告)日：2024-06-19
申请号：EP22856372.2
申请日：2022-06-09
IPC分类号： C07D409/14 , C07D295/15 , C07D409/12 , C07D241/08 , A61K31/495 , A61K31/496 , A61K9/127 , A61K9/00 , A61P27/02
CPC分类号： A61K9/127 , A61K31/495 , A61P27/02 , C07D241/08 , C07D295/15 , C07D409/14 , C07D333/30 , A61K9/0019 , A61K9/0053
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公开(公告)号：EP4375274A1
公开(公告)日：2024-05-29
申请号：EP22845935.0
申请日：2022-07-20
发明人： INAGAKI, Yusuke , WASHIO, Takuya , KOIZUMI, Yuka , TOYA, Hiroki , YAMASHITA, Yumi , KURIWAKI, Ikumi , MAEDA, Junko , KOIKE, Takanori , KAMIKUBO, Takashi , YAMAKI, Susumu , KURAMOTO, Kazuyuki , SABA, Kengo , TOMIYAMA, Hiroshi , IWAI, Yoshinori , NAKAMURA, Akihiko
IPC分类号： C07D237/32 , A61K31/502 , A61K31/5025 , A61K31/504 , A61P25/00 , A61P25/28 , A61P29/00 , A61P37/02 , C07D237/26 , C07D237/34 , C07D401/12 , C07D403/12 , C07D405/12 , C07D405/14 , C07D409/12 , C07D471/04 , C07D487/04 , C07D491/044 , C07D491/052 , C07D491/107 , C07D495/04
CPC分类号： A61K31/502 , A61K31/5025 , A61K31/504 , A61P25/28 , A61P25/00 , A61P29/00 , A61P37/02 , C07D237/26 , C07D237/32 , C07D237/34 , C07D401/12 , C07D403/12 , C07D405/12 , C07D405/14 , C07D409/12 , C07D471/04 , C07D487/04 , C07D491/044 , C07D491/052 , C07D491/107 , C07D495/04
摘要： An object of the present invention is to provide a pharmaceutical composition, in particular, a compound suitable for preventing and/or treating inflammatory diseases and/or neurodegenerative disease. The present inventors have conducted intensive studies to find a compound having an inhibitory effect on NLRP3 inflammasome activation and found that an annulated pyridazine compound has an inhibitory effect on NLRP3 inflammasome activation, thus completing the present invention. The annulated pyridazine compound of the present invention is expected to serve as a prophylactic and/or therapeutic agent for inflammatory diseases and/or neurodegenerative diseases.
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公开(公告)号：EP4373819A1
公开(公告)日：2024-05-29
申请号：EP22748406.0
申请日：2022-07-18
申请人： Neophore Limited
发明人： BLAGG, Julian , DRYSDALE, Martin , CLARK, David , WINSHIP, Paul
IPC分类号： C07D405/12 , C07D209/44 , C07D401/04 , C07D403/12 , C07D413/12 , C07D401/12 , C07D405/14 , C07D217/06 , C07D401/14 , C07D471/04 , C07D409/12 , C07D403/14 , C07F5/02 , A61P35/00 , A61K31/4035 , A61K31/4375 , A61K31/4725 , A61K31/496 , A61K31/501
CPC分类号： C07D405/12 , C07D209/44 , C07D401/04 , C07D403/12 , C07D413/12 , C07D401/12 , C07D405/14 , C07D217/06 , C07D401/14 , C07D471/04 , C07D409/12 , C07D403/14 , C07F5/022 , A61P35/00
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