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    옥소카본-, 유사옥소카본- 및 라디알렌 화합물, 및 이들의용도
    1.
    发明公开
    옥소카본-, 유사옥소카본- 및 라디알렌 화합물, 및 이들의용도 有权
    奥昔康宁，PSEUDOOXOCARBON-和RADIALENEE化合物及其使用

    公开(公告)号：KR1020080097146A

    公开(公告)日：2008-11-04

    申请号：KR1020080040353

    申请日：2008-04-30

    Applicant: 노발레드 게엠베하

    Inventor： 하르트만,호르스트 ,  차이카,올라프 ,  룩스,안드레아스 ,  빌만,슈테펜

    IPC: C07C49/385 ,  C07C255/31 ,  C07C325/02

    CPC classification number: H01L51/005 ,  C07C13/04 ,  C07C13/06 ,  C07C13/11 ,  C07C13/19 ,  C07C49/39 ,  C07C49/395 ,  C07C49/653 ,  C07C255/31 ,  C07C255/40 ,  C07C255/51 ,  C07C261/04 ,  C07C325/02 ,  C07C2601/02 ,  C07C2601/04 ,  C07C2601/08 ,  C07C2601/14 ,  C07C2601/16 ,  C07D213/53 ,  C07D333/24 ,  C09B11/02 ,  C09B47/04 ,  C09B57/00 ,  C09B57/008 ,  H01L51/002 ,  H01L51/0051 ,  H01L51/0067 ,  H01L51/0068 ,  Y02E10/549 ,  Y02P70/521

    Abstract: An organic mesomeric compound can be used as a dopant for doping of an organic semiconductor, be more easily treated in a manufacturing process, and form an electronic component capable of manufacturing an organic semiconductor material. An organic mesomeric compound is an oxocarbon-, homooxocarbon- and radiallen compound of the chemical formula 1. In the chemical formula 1, n = 1-4; each of X1, X2, X3, X4 and X5 is selected from a group consisting of C(CN)2, (CF3)C(CN), (NO2)C(CN), C(halogen)2, C(CF3)2, NCN, O, S, NR1, chemical formula A-W4; Y is CN, NO2, and COR1, or a perhalogenated alkyl; an aryl or Ar is substituted or non-substituted aromatic hydrocarbon or biaryl or arbitrarily polycyclic; a hetaryl is substituted or non-substituted aromatic heterocyclic compound or biheteroaryl, preferably, an electronic-shortage aromatic heterocyclic compound or biheteroaryl, arbitrarily, a poly necleus aromatic heterocyclic compound or biheteroaryl, or partially or completely hydrogenated or fluoridizedan aromatic heterocyclic compound or biheteroaryl; and R1-R8 are independently selected from hydrogen, halogen, CN, NO2, COR1, alkyl, alkoxy, and heteroaryl.

    Abstract translation: 有机介子化合物可以用作有机半导体的掺杂剂，在制造过程中更易于处理，并形成能够制造有机半导体材料的电子部件。 有机介体化合物是化学式1的氧化碳 - ，高氧化碳 - 和 - - - 离子化合物。在化学式1中，n = 1-4; X1，X2，X3，X4和X5各自选自C（CN）2，（CF 3）C（CN），（NO 2）C（CN），C（卤素）2，C（CF 3） 2，NCN，O，S，NR1，化学式A-W4; Y是CN，NO 2和COR 1，或全卤代烷基; 芳基或Ar是取代或未取代的芳烃或联芳基或任意多环; 杂芳基是取代或未取代的芳族杂环化合物或双杂芳基，优选电子缺乏芳族杂环化合物或双杂芳基，任意的多聚氰胺杂环化合物或双杂芳基，或部分或完全氢化或氟化芳族杂环化合物或双杂芳基; 并且R 1 -R 8独立地选自氢，卤素，CN，NO 2，COR 1，烷基，烷氧基和杂芳基。

    신규한 인다닐리덴 화합물
    4.
    发明公开
    신규한 인다닐리덴 화합물 失效
    신규한인다닐리덴화합물

    公开(公告)号：KR1020030059238A

    公开(公告)日：2003-07-07

    申请号：KR1020037006348

    申请日：2001-10-30

    Applicant: 짐리즈 게엠베하 운트 캄파니 카게

    Inventor： 코흐,오스카 ,  딜크,에리히 ,  랑그너,롤란드 ,  존콕,윌리암

    IPC: C07C255/40

    CPC classification number: C07D319/14 ,  A61K8/40 ,  A61K8/498 ,  A61K8/585 ,  A61Q17/04 ,  C07C255/40 ,  C07C2601/14 ,  C07C2602/08 ,  C07F7/0854

    Abstract: 피부 및 모발 보호용 화장용 제제 중 UV-A 필터로서뿐만 아니라 기술적 용도에 신규한 인다닐리덴 화합물을 사용할 수 있다.

    Abstract translation: 2-（1-亚茚基）-3-氧代 - 链烷酸衍生物（I）（包括酯，酰胺和腈）是新的。 式（I）的茚亚基化合物是新的。 R1-R4 = H，1-20C烷基或5-10C环烷基; 或其中至少一个CH 2被O，3-20C烯基，3-20C炔基或S'替代的2-20C烷基; 或相邻C上的R 1 -R 4可一起形成任选取代的1-4C亚烷基; S'=硅烷，低聚硅烷或聚硅氧烷基团; R5-R8 = H，1-20C烷基，5-10C环烷基，1-20C烷氧基，5-10C环烷氧基，OH，乙酰氧基，乙酰氨基，COOH，烷氧基羰基或氨基甲酰基; 或其中至少一个CH 2被O，3-20C烯基，3-20C炔基或S'替代的2-20C烷基; 或者相邻C上的两个R5-R8可以一起形成含有至多3个杂原子（特别是O或N）并且任选被外环= O（酮基）取代的5-7元环; X = CN，CON（R）2或COOR; R = H或1-4C烷基; n = 0或1.如果n为1，则R 9 -R 11 = H，1-20C烷基，5-10C环烷基，芳基或杂芳基; 或两个R9-R11一起形成任选含有至多3个杂原子（特别是O或N）的3-7元环; 如果n为0，则CR 9 R 10 =芳基或杂芳基。

    과산화수소 검출용 형광 나노 프로브 및 그 제조방법
    7.
    发明公开
    과산화수소 검출용 형광 나노 프로브 및 그 제조방법 有权
    用于检测过氧化氢的荧光纳米颗粒及其制备方法

    公开(公告)号：KR1020120121937A

    公开(公告)日：2012-11-07

    申请号：KR1020110039143

    申请日：2011-04-26

    Applicant: 한국과학기술연구원

    Inventor： 김세훈 ,  권익찬 ,  김재경 ,  임창근 ,  허정윤

    IPC: C09K11/06 ,  C07C69/84 ,  G01N31/22 ,  G01N21/76

    CPC classification number: C07D239/60 ,  C07C39/373 ,  C07C47/565 ,  C07C49/248 ,  C07C49/747 ,  C07C69/732 ,  C07C69/94 ,  C07C255/36 ,  C07C255/40 ,  C07C255/41 ,  C07C309/73 ,  C07C317/46 ,  C07C2602/08 ,  C07D403/10 ,  Y10T436/206664

    Abstract: PURPOSE: A fluorescent nanoprobe for detecting hydrogen peroxide is provided to be quickly embodied by organic base in nanoparticles, and to be used for detecting sulfuric acid in rear time and to be used for cell-imaging in vivo-imaging, chemical analysis, etc. CONSTITUTION: A fluorescent nanoprobe for detecting hydrogen peroxide is represented by chemical formula 1. In chemical formula 1, A is an electron-accepting substituent selected ester, aldehyde, nitrile, nitrobenzene, sulfonated benzene, indane, babituric acid, and derivatives thereof, an electron-accepting substituent. The fluorescent nanoprobe comprises the sulfonated benzene compound and water. A manufacturing method of the fluorescent nanoprobe comprises: a step of mixing sulfonated benzene compound represented by chemical formula 3 and organic solvent; and a step of obtaining fluoresncent nanoprobe by removing the organic solvent.

    Abstract translation: 目的：提供一种用于检测过氧化氢的荧光探针，可以通过纳米颗粒中的有机碱快速实现，并用于后期检测硫酸，并用于体内成像，化学分析等细胞成像。 组成：用于检测过氧化氢的荧光纳米探针由化学式1表示。在化学式1中，A是选择的电子接受性取代基酯，醛，腈，硝基苯，磺化苯，茚满，巴布酸及其衍生物， 受电子取代基。 荧光纳米探针包含磺化苯化合物和水。 荧光纳米探针的制造方法包括：将由化学式3表示的磺化苯化合物与有机溶剂混合的步骤; 以及通过除去有机溶剂获得荧光剂纳米探针的步骤。

    인데논카르복실산 유도체 및 당뇨병 및 이상지혈증의 치료및 예방을 위한 이의 용도
    8.
    发明公开
    인데논카르복실산 유도체 및 당뇨병 및 이상지혈증의 치료및 예방을 위한 이의 용도 无效
    吲哚羧酸衍生物及其用于治疗和预防糖尿病和糖尿病的用途

    公开(公告)号：KR1020050091086A

    公开(公告)日：2005-09-14

    申请号：KR1020057012917

    申请日：2003-12-16

    Applicant: 메르크 파텐트 게엠베하

    Inventor： 애드제,나탈리 ,  브루네,미쉘 ,  로쉐,디디에 ,  제일러,장-자크 ,  이본,슈테판 ,  기야드-댕그레몽,발레 ,  콘타르드,프란시스 ,  게리에르,다니엘 ,  페랑,제라르 ,  본옴므,이브스

    IPC: C07C309/65 ,  C07C323/34 ,  A61P3/10 ,  A61P3/06

    CPC classification number: C07C323/56 ,  C07C45/46 ,  C07C45/673 ,  C07C45/68 ,  C07C49/747 ,  C07C49/755 ,  C07C59/72 ,  C07C59/90 ,  C07C65/40 ,  C07C67/30 ,  C07C67/31 ,  C07C69/712 ,  C07C69/736 ,  C07C69/76 ,  C07C205/45 ,  C07C211/60 ,  C07C229/18 ,  C07C233/33 ,  C07C251/44 ,  C07C255/40 ,  C07C309/65 ,  C07C317/44 ,  C07C323/22 ,  C07C323/52 ,  C07C2602/08 ,  C07C2602/10 ,  C07C2602/42 ,  C07C47/575

    Abstract: The present invention relates to a compound of the formula ((I): in which: n is an integer chosen from 1, 2 and 3; Y represents O; N-OR9, in which R9represents H or a saturated hydrocarbon-based aliphatic group; CR10R 11, in which R10 and R11, which may be identical or different, represent H or a saturated hydrocarbon-based aliphatic group; R1 and R2, which may be identical or different, represent H or a saturated aliphatic hydrocarbon-based chain; or alternatively R1 and R2 together form an optionally substituted saturated aliphatic hydrocarbon-based chain; the radicals R3 and R4, which may be identical or different, take any of the is meanings given above for R1 and R2, or alternatively R1 and the group R4 borne by the carbon alpha to CR1R 2 represent nothing and a double bond links the CR1R 2 carbon to the alpha CR3R4 carbon; or alternatively one of the radicals R1 and R2 forms with one of the radicals R3 and R4 an optionally substituted saturated or unsaturated aliphatic hydrocarbon- based chain; one of the radicals R5 and R6 represents W, and the other represents Z which is chosen from a saturated or unsaturated aliphatic hydrocarbon-based radical; an optionally substituted, saturated, unsaturated and/or aromatic carbocyclic or heterocyclic radical; a radical -alk-Cy, in which alk represents an alkylene chain and Cy represents an optionally substituted saturated, unsaturated and/or aromatic heterocyclic or carbocyclic radical; W represents -XL-CO2R7;-X-L-Tet, in which X and L are as defined below and Tet represents optionally substituted tetrazole; in which L represents a saturated or unsaturated aliphatic hydrocarbon-based chain, which is optionally substituted and/or optionally interrupted by optionally substituted arylene; X represents O; NR8, in which R8 represents H; a saturated aliphatic hydrocarbon-based group; a group -CO-R' or -SO2-R', in which R' takes any of the meanings given below for R7 with the exception of H; or R8 represents an optionally substituted aromatic carbocyclic group; or X represent S(O)m, in which m is chosen from 0, 1 and 2; R7 represents H; a saturated or unsaturated aliphatic hydrocarbon-based group; an optionally substituted, saturated, unsaturated and/or aromatic carbocyclic group; an optionally substituted, saturated, unsaturated and/or aromatic heterocyclic group; and the pharmaceutically acceptable derivatives, salts, solvates and stereoisomers thereof, and also mixtures thereof in all proportions, which can be used in the treatment of dyslipidaemia, atherosclerosis and diabetes.

    Abstract translation: 本发明涉及式（（I）的化合物：其中：n是选自1,2和3的整数; Y表示O; N-OR 9，其中R9表示H或饱和烃基脂族基团 CR10R 11，其中R10和R11可以相同或不同，表示H或饱和烃基脂族基; R1和R2可以相同或不同，代表H或饱和脂族烃基链; 或者R 1和R 2一起形成任选取代的饱和脂族烃基链;基团R 3和R 4可以相同或不同，具有上面对R 1和R 2给出的任何含义，或者R 1和R 4 由CR1R 2的碳α承担，并且双键将CR1R2碳连接到αCR 3 R 4碳;或者基团R 1和R 2中的一个与基团R 3和R 4之一形成任选取代的饱和或不饱和脂族 地烃基 基于链的; 基团R5和R6之一表示W，另一个表示选自饱和或不饱和脂族烃基的基团的Z; 任选取代的饱和，不饱和和/或芳族碳环或杂环基; 一个自由基-alk-Cy，其中alk代表亚烷基链，Cy代表任选取代的饱和，不饱和和/或芳族杂环或碳环基团; W表示-XL-CO 2 R 7; -X-L-Tet，其中X和L如下所定义，Tet表示任选取代的四唑; 其中L表示饱和或不饱和的脂族烃基链，其任选被任选取代的和/或任选地被任选取代的亚芳基中断; X表示O; NR8，其中R8表示H; 饱和脂族烃基; 基团-CO-R'或-SO 2 -R'，其中R'取代以下对R 7的任何含义，除了H; 或R 8表示任选取代的芳族碳环基团; 或X表示S（O）m，其中m选自0,1和2; R7表示H; 饱和或不饱和脂族烃基; 任选取代的，饱和的，不饱和的和/或芳族的碳环基团; 任选取代的饱和，不饱和和/或芳族杂环基; 和其药学上可接受的衍生物，盐，溶剂合物和立体异构体，以及其各种比例的混合物，其可用于治疗血脂异常，动脉粥样硬化和糖尿病。

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