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1.发明授权公开(公告)号：US08728803B2
公开(公告)日：2014-05-20
申请号：US12380551
申请日：2009-02-26
申请人： Vicki S. Thompson , William A. Apel , David W. Reed , Brady D. Lee , David N. Thompson , Francisco F. Roberto , Jeffrey A. Lacey
发明人： Vicki S. Thompson , William A. Apel , David W. Reed , Brady D. Lee , David N. Thompson , Francisco F. Roberto , Jeffrey A. Lacey
CPC分类号： C12N9/88 , C12N9/00 , C12N9/1029 , C12N15/74 , C12N15/75 , C12Y203/01009 , C12Y402/01055
摘要： Isolated and/or purified polypeptides and nucleic acid sequences encoding polypeptides from Alicyclobacillus acidocaldarius are provided. Further provided are methods for modulating or altering metabolism in a cell using isolated and/or purified polypeptides and nucleic acid sequences from Alicyclobacillus acidocaldarius.
摘要翻译： 提供了分离和/或纯化的多肽和编码来自酸热环酸杆菌的多肽的核酸序列。 还提供了使用分离和/或纯化的多肽和酸性脂多酸杆菌的核酸序列调节或改变细胞代谢的方法。
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公开(公告)号：US08426185B2
公开(公告)日：2013-04-23
申请号：US12927495
申请日：2010-11-15
申请人： David N. Thompson , William A. Apel , Vicki S. Thompson , David W. Reed , Jeffrey A. Lacey , Emily D. Henriksen
发明人： David N. Thompson , William A. Apel , Vicki S. Thompson , David W. Reed , Jeffrey A. Lacey , Emily D. Henriksen
IPC分类号： C12N9/42 , C12N9/14 , C12N15/00 , C12P21/06 , C12P19/34 , C12Q1/34 , C07G15/00 , C08B37/00 , D21C1/00 , C07H21/04 , C07K1/00
CPC分类号： C12N9/2402 , C12N9/2445 , C12N9/2471 , C12N9/248 , C12N15/52 , C12Y302/01021 , C12Y302/01023 , C12Y302/01037 , C12Y302/01055 , C12Y302/01091
摘要： Isolated and/or purified polypeptides and nucleic acid sequences encoding polypeptides from Alicyclobacillus acidocaldarius are provided. Further provided are methods of at least partially degrading, cleaving, or removing polysaccharides, lignocellulose, cellulose, hemicellulose, lignin, starch, chitin, polyhydroxybutyrate, heteroxylans, glycosides, xylan-, glucan-, galactan-, or mannan-decorating groups using isolated and/or purified polypeptides and nucleic acid sequences encoding polypeptides from Alicyclobacillus acidocaldarius.
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3.发明申请公开(公告)号：US20120288932A1
公开(公告)日：2012-11-15
申请号：US13517887
申请日：2012-06-14
CPC分类号： C07K14/195
摘要： Isolated and/or purified polypeptides and nucleic acid sequences encoding polypeptides from Alicyclobacillus acidocaldarius are provided. Further provided are methods for transporting sugars across cell membranes using isolated and/or purified polypeptides and nucleic acid sequences from Alicyclobacillus acidocaldarius.
摘要翻译： 提供了分离和/或纯化的多肽和编码来自酸热环酸杆菌的多肽的核酸序列。 进一步提供的是使用分离和/或纯化的多肽和酸性脂多酸杆菌的核酸序列在细胞膜上运输糖的方法。
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4.发明申请Thermophilic and thermoacidophilic biopolymer-degrading genes and enzymes from alicyclobacillus acidocaldarius and related organisms, methods 有权嗜热和热嗜酸性生物聚合物降解基因和酸性脂肪酸杆菌和相关生物的酶，方法公开(公告)号：US20110143395A1
公开(公告)日：2011-06-16
申请号：US12927495
申请日：2010-11-15
申请人： David N. Thompson , William A. Apel , Vicki S. Thompson , David W. Reed , Jeffrey A. Lacey , Emily D. Henriksen
发明人： David N. Thompson , William A. Apel , Vicki S. Thompson , David W. Reed , Jeffrey A. Lacey , Emily D. Henriksen
CPC分类号： C12N9/2402 , C12N9/2445 , C12N9/2471 , C12N9/248 , C12N15/52 , C12Y302/01021 , C12Y302/01023 , C12Y302/01037 , C12Y302/01055 , C12Y302/01091
摘要： Isolated and/or purified polypeptides and nucleic acid sequences encoding polypeptides from Alicyclobacillus acidocaldarius are provided. Further provided are methods of at least partially degrading, cleaving, or removing polysaccharides, lignocellulose, cellulose, hemicellulose, lignin, starch, chitin, polyhydroxybutyrate, heteroxylans, glycosides, xylan-, glucan-, galactan-, or mannan-decorating groups using isolated and/or purified polypeptides and nucleic acid sequences encoding polypeptides from Alicyclobacillus acidocaldarius.
摘要翻译： 提供了分离和/或纯化的多肽和编码来自酸热环酸杆菌的多肽的核酸序列。 还提供了使用分离的至少部分降解，切割或除去多糖，木质纤维素，纤维素，半纤维素，木质素，淀粉，几丁质，聚羟基丁酸酯，异木聚糖，糖苷，木聚糖，葡聚糖，半乳聚糖或甘露聚糖装饰基团的方法 和/或编码来自酸性脂多酸杆菌的多肽的纯化多肽和核酸序列。
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5.发明授权Thermal and acid tolerant beta-xylosidases, genes encoding, related organisms, and methods 有权热和酸耐受性β-木糖苷酶，编码基因，相关生物体和方法公开(公告)号：US07923234B2
公开(公告)日：2011-04-12
申请号：US12321636
申请日：2009-01-23
申请人： David N. Thompson , Vicki S. Thompson , Kastli D. Schaller , William A. Apel , Jeffrey A. Lacey , David W. Reed
发明人： David N. Thompson , Vicki S. Thompson , Kastli D. Schaller , William A. Apel , Jeffrey A. Lacey , David W. Reed
CPC分类号： C12Y302/01037 , C12N9/2402 , C12N9/248 , C12N9/2482 , C12Y302/01055 , D21C5/005 , D21C11/0007
摘要： Isolated and/or purified polypeptides and nucleic acid sequences encoding polypeptides from Alicyclobacillus acidocaldarius and variations thereof are provided. Further provided are methods of at least partially degrading xylotriose and/or xylobiose using isolated and/or purified polypeptides and nucleic acid sequences encoding polypeptides from Alicyclobacillus acidocaldarius and variations thereof.
摘要翻译： 提供了分离和/或纯化的多肽和编码来自酸热环酸杆菌的多肽的核酸序列及其变体。 还提供了使用分离的和/或纯化的多肽和编码来自酸热环酸杆菌的多肽的核酸序列及其变体来至少部分降解木三糖和/或木二糖的方法。
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6.发明授权Thermophilic and thermoacidophilic biopolymer-degrading genes and enzymes from alicyclobacillus acidocaldarius and related organisms, methods 有权嗜热和热嗜酸性生物聚合物降解基因和酸性脂肪酸杆菌和相关生物的酶，方法公开(公告)号：US07858353B2
公开(公告)日：2010-12-28
申请号：US12322359
申请日：2009-01-29
申请人： David N. Thompson , William A. Apel , Vicki S. Thompson , David W. Reed , Jeffrey A. Lacey , Emily D. Henriksen
发明人： David N. Thompson , William A. Apel , Vicki S. Thompson , David W. Reed , Jeffrey A. Lacey , Emily D. Henriksen
IPC分类号： C12N9/42 , C12N9/14 , C12N9/00 , C12N15/00 , C12P21/06 , C12P19/34 , C12Q1/34 , C08B37/00 , D21C1/00 , C07H21/04
CPC分类号： C12Y302/01055 , C12N9/2402 , C12N15/52 , Y02W10/45
摘要： Isolated and/or purified polypeptides and nucleic acid sequences encoding polypeptides from Alicyclobacillus acidocaldarius are provided. Further provided are methods of at least partially degrading, cleaving, or removing polysaccharides, lignocellulose, cellulose, hemicellulose, lignin, starch, chitin, polyhydroxybutyrate, heteroxylans, glycosides, xylan-, glucan-, galactan, or mannan-decorating groups using isolated and/or purified polypeptides and nucleic acid sequences encoding polypeptides from Alicyclobacillus acidocaldarius.
摘要翻译： 提供了分离和/或纯化的多肽和编码来自酸热环酸杆菌的多肽的核酸序列。 进一步提供的是使用分离和分离的多糖，木素纤维素，纤维素，半纤维素，木质素，淀粉，几丁质，聚羟基丁酸酯，异木糖，糖苷，木聚糖，葡聚糖，半乳聚糖或甘露聚糖装饰剂至少部分降解，切割或除去多糖， 或纯化的多肽和编码来自酸热环酸杆菌的多肽的核酸序列。
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7.发明申请Alteration and modulation of protein activity by varying post-translational modification 有权通过改变翻译后修饰来改变和调节蛋白质活性公开(公告)号：US20100203583A1
公开(公告)日：2010-08-12
申请号：US12655993
申请日：2010-01-12
CPC分类号： C12N9/2402 , C12N9/1048 , C12N9/1051 , C12N9/1288 , C12N9/2437 , C12N9/2477 , C12N9/2482 , C12P21/00 , C12P21/005 , C12Y302/01004 , C12Y302/01008 , Y02P20/52
摘要： Embodiments of the invention include methods of altering the enzymatic activity or solubility of an extremophilic enzyme or post-translationally modifying a protein of interest via using isolated or partially purified glycosyltransferases and/or post-translational modification proteins, extracts of cells comprising glycosyltransferases and/or post-translational modification proteins, and/or in cells comprising one or more glycosyltransferases and/or post-translational modification proteins.
摘要翻译： 本发明的实施方案包括通过使用分离或部分纯化的糖基转移酶和/或翻译后修饰蛋白来改变极端酶的酶活性或溶解度或翻译后修饰目的蛋白质的方法，包含糖基转移酶和/或 和/或包含一个或多个糖基转移酶和/或翻译后修饰蛋白的细胞。
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公开(公告)号：US07727755B2
公开(公告)日：2010-06-01
申请号：US11266063
申请日：2005-11-02
IPC分类号： C12N9/42
CPC分类号： C12P19/14 , C12N9/2437 , C12N9/2477 , C12N9/248 , C12P7/06 , C12Y302/01004 , Y02E50/17
摘要： An enzyme isolated from an extremophilic microbe, and a method for utilizing same is described, and wherein the enzyme displays optimum enzymatic activity at a temperature of greater than about 80° C., and a pH of less than about 2, and further may be useful in methodology including pretreatment of a biomass so as to facilitate the production of an end product.
摘要翻译： 描述了从极端微生物分离的酶及其利用方法，其中酶在大于约80℃的温度和小于约2的pH下显示最佳的酶活性，并且还可以 可用于包括预处理生物质以便促进最终产品生产的方法。
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9.发明申请Thermal and acid tolerant beta-xylosidases, genes encoding, related organisms, and methods 有权热和酸耐受性β-木糖苷酶，编码基因，相关生物体和方法公开(公告)号：US20090226978A1
公开(公告)日：2009-09-10
申请号：US12321636
申请日：2009-01-23
申请人： David N. Thompson , Vicki S. Thompson , Kastli D. Schaller , William A. Apel , David W. Reed , Jeffrey A. Lacey
发明人： David N. Thompson , Vicki S. Thompson , Kastli D. Schaller , William A. Apel , David W. Reed , Jeffrey A. Lacey
CPC分类号： C12Y302/01037 , C12N9/2402 , C12N9/248 , C12N9/2482 , C12Y302/01055 , D21C5/005 , D21C11/0007
摘要： Isolated and/or purified polypeptides and nucleic acid sequences encoding polypeptides from Alicyclobacillus acidocaldarius and variations thereof are provided. Further provided are methods of at least partially degrading xylotriose and/or xylobiose using isolated and/or purified polypeptides and nucleic acid sequences encoding polypeptides from Alicyclobacillus acidocaldarius and variations thereof.
摘要翻译： 提供了分离和/或纯化的多肽和编码来自酸热环酸杆菌的多肽的核酸序列及其变体。 还提供了使用分离的和/或纯化的多肽和编码来自酸热环酸杆菌的多肽的核酸序列及其变体来至少部分降解木三糖和/或木二糖的方法。
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10.发明授权Thermophilic and thermoacidophilic glycosylation genes and enzymes from Alicyclobacillus acidocaldarius and related organisms, methods 有权嗜热和热嗜酸性糖基化基因和酸性脂肪酸杆菌和相关生物的酶，方法公开(公告)号：US09234228B2
公开(公告)日：2016-01-12
申请号：US12380450
申请日：2009-02-26
CPC分类号： C12N9/1051 , C12N9/1048 , C12N9/1288 , C12P21/00 , C12P21/005 , C12Y204/00 , C12Y204/01083 , C12Y207/08
摘要： Isolated and/or purified polypeptides and nucleic acid sequences encoding polypeptides from Alicyclobacillus acidocaldarius are provided. Further provided are methods for glycosylating and/or post-translationally modifying proteins using isolated and/or purified polypeptides and nucleic acid sequences from Alicyclobacillus acidocaldarius.
摘要翻译： 提供了分离和/或纯化的多肽和编码来自酸热环酸杆菌的多肽的核酸序列。 还提供了使用分离的和/或纯化的多肽和来自酸性脂环酸杆菌的核酸序列糖基化和/或翻译后修饰蛋白质的方法。
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