公开(公告)号：US09138491B2

公开(公告)日：2015-09-22

申请号：US14110138

申请日：2011-04-07

Applicant: Moon-Hee Sung ,  Yong Taik Lim ,  Young-Woock Noh ,  Il Han Lee ,  Hyun Min Kim

Inventor： Moon-Hee Sung ,  Yong Taik Lim ,  Young-Woock Noh ,  Il Han Lee ,  Hyun Min Kim

IPC: A61K49/12 ,  A61B5/055 ,  A61K49/18

CPC classification number: A61K49/126 ,  A61K49/1863 ,  A61K49/1872

Abstract: The present invention relates to a nano-composite containing anionic and cationic polymers and a method for preparing thereof, and more particularly to a poly-gamma-glutamic acid (γ-PGA)/chitosan/manganese iron oxide nanoparticle composite prepared by encapsulating iron oxide-based nanoparticles in a γ-PGA/chitosan polymer composite using the ionic self-assembly properties of poly-gamma-glutamic acid (γ-PGA) and chitosan, which are biocompatible polymer materials, and to a method for preparing thereof.The present invention provides a magnetic resonance imaging nano-contrast agent based on a nanoparticle composite including iron oxide-based nanoparticles encapsulated in a self-assembled composite of anionic poly-gamma-glutamic acid (γPGA) and cationic chitosan. The iron oxide-based nanoparticles encapsulated in the composite interact with each other to produce a synergistic effect on the amplification of magnetic resonance signals, and thus have an relatively excellent contrast effect compared to when they exist as single particles.

Abstract translation: 本发明涉及含有阴离子和阳离子聚合物的纳米复合物及其制备方法，更具体地涉及通过包封氧化铁制备的聚-γ-谷氨酸（γ-PGA）/壳聚糖/锰铁氧体纳米颗粒复合材料 基于聚-γ-谷氨酸（γ-PGA）和壳聚糖的离子自组装性质的γ-PGA /壳聚糖复合材料的生物相容性聚合物材料的制备方法。 本发明提供一种基于纳米颗粒复合材料的磁共振成像纳米造影剂，其包括封装在阴离子聚-γ-谷氨酸（γPGA）和阳离子壳聚糖的自组装复合物中的基于氧化铁的纳米颗粒。 封装在复合材料中的基于氧化铁的纳米颗粒彼此相互作用以对磁共振信号的扩增产生协同效应，因此与作为单个颗粒存在时相比具有相对优异的对比效果。

公开(公告)号：US08576798B2

公开(公告)日：2013-11-05

申请号：US12860148

申请日：2010-08-20

Applicant: Cheon-moo Lee ,  Il-han Lee ,  Soo-hyun Yoo

Inventor： Cheon-moo Lee ,  Il-han Lee ,  Soo-hyun Yoo

IPC: H04W4/00 ,  H04W36/00 ,  H04J3/26 ,  G06F15/16

CPC classification number: H04L67/125 ,  H04L12/413 ,  H04W76/10

Abstract: A data communication apparatus and method that permits communication between two devices without having to perform a complicated initial connection procedure. A communication unit conducts data transmission/reception with an external data communication apparatus, and a controller controls the communication unit to operate in one of a network mode or a broadcast mode. The network mode conducts network communication via connection through an initial connection procedure with the external data communication apparatus and the broadcast mode receives or transmits data to/from the external data communication apparatus according to a predetermined broadcast method.

Abstract translation: 一种数据通信装置和方法，其允许两个设备之间的通信，而不必执行复杂的初始连接过程。 通信单元与外部数据通信装置进行数据发送/接收，并且控制器控制通信单元以网络模式或广播模式之一进行操作。 网络模式通过与外部数据通信装置的初始连接过程的连接进行网络通信，并且广播模式根据预定的广播方法向外部数据通信装置接收或发送数据。

公开(公告)号：US08236940B2

公开(公告)日：2012-08-07

申请号：US12532605

申请日：2008-03-21

Applicant: Moon Hee Sung ,  Chul Joong Kim ,  Seung-Pyo Hong ,  Haryoung Poo ,  Il Han Lee ,  Ji Yeon Kim ,  Kwang Kim

Inventor： Moon Hee Sung ,  Chul Joong Kim ,  Seung-Pyo Hong ,  Haryoung Poo ,  Il Han Lee ,  Ji Yeon Kim ,  Kwang Kim

IPC: C07H21/04 ,  C12N15/63 ,  C12N1/21 ,  C12P21/00

CPC classification number: C12N15/746 ,  C12N9/1276

Abstract: Disclosed herein are an aldolase gene promoter and the use thereof, more particularly, disclosed are a promoter of aldolase gene derived from Lactobacillus casei, having a base sequence of SEQ ID NO: 1, an expression vector containing said promoter, and a recombinant microorganism transformed with said expression vector. The recombinant microorganism transformed with the expression vector containing the disclosed promoter can effectively express a target protein on the surface thereof, and thus will be useful as vaccine vehicles and the like.

Abstract translation: 本文公开了醛缩酶基因启动子及其用途，更具体地，公开了源自干酪乳杆菌的醛缩酶基因的启动子，其具有SEQ ID NO：1的碱基序列，含有所述启动子的表达载体和转化的重组微生物 与所述表达载体。 用含有公开的启动子的表达载体转化的重组微生物可以在其表面上有效地表达靶蛋白质，因此可用作疫苗载体等。

公开(公告)号：US20110096850A1

公开(公告)日：2011-04-28

申请号：US12860148

申请日：2010-08-20

Applicant: Cheon-moo LEE ,  Il-han LEE ,  Soo-hyun YOO

Inventor： Cheon-moo LEE ,  Il-han LEE ,  Soo-hyun YOO

IPC: H04L27/00

CPC classification number: H04L67/125 ,  H04L12/413 ,  H04W76/10

Abstract: A data communication apparatus and method that permits communication between two devices without having to perform a complicated initial connection procedure. A communication unit conducts data transmission/reception with an external data communication apparatus, and a controller controls the communication unit to operate in one of a network mode or a broadcast mode. The network mode conducts network communication via connection through an initial connection procedure with the external data communication apparatus and the broadcast mode receives or transmits data to/from the external data communication apparatus according to a predetermined broadcast method.

Abstract translation: 一种数据通信装置和方法，其允许两个设备之间的通信，而不必执行复杂的初始连接过程。 通信单元与外部数据通信装置进行数据发送/接收，并且控制器控制通信单元以网络模式或广播模式之一进行操作。 网络模式通过与外部数据通信装置的初始连接过程的连接进行网络通信，并且广播模式根据预定的广播方法向外部数据通信装置接收或发送数据。

公开(公告)号：US07626564B2

公开(公告)日：2009-12-01

申请号：US11246122

申请日：2005-10-11

Applicant: Jung-Kook Park ,  Il-Han Lee ,  Seung-Kyun Hong

Inventor： Jung-Kook Park ,  Il-Han Lee ,  Seung-Kyun Hong

IPC: G09G3/30

CPC classification number: G09G3/30 ,  G09G2300/06 ,  G09G2310/0248 ,  G09G2310/08 ,  G09G2330/023

Abstract: An apparatus for driving an electroluminescence display panel having an icon area where predetermined icons are displayed according to input icon data and a dot-matrix area where variable images are displayed according to input dot-matrix data. A current that is discharged after the dot-matrix area is driven in each horizontal drive period is applied to at least one of driver power supply terminals of the icon area and the dot-matrix area.

Abstract translation: 根据输入的图形数据和根据输入的点阵数据显示可变图像的点矩阵区域，驱动具有显示预定图标的图标区域的电致发光显示面板的装置。 在每个水平驱动周期中驱动点阵区域之后放电的电流被施加到图标区域和点阵区域的至少一个驱动器电源端子。

公开(公告)号：US20090135106A1

公开(公告)日：2009-05-28

申请号：US12195337

申请日：2008-08-20

Applicant: Hyo-Jin Lee ,  Il-Han Lee ,  Yoon Kang

Inventor： Hyo-Jin Lee ,  Il-Han Lee ,  Yoon Kang

IPC: G09G3/30

CPC classification number: G09G3/3233 ,  G09G2300/0842 ,  G09G2310/08

Abstract: An organic light emitting display and a driving method for the same for preventing picture playback disruption during the playback of a moving picture. An organic light emitting display includes: a display region including a plurality of pixels for displaying an image; a frame memory for storing image signals of the image; a data driver for receiving the image signals to generate data signals; a scan driver for generating scan signals; and a controller for controlling the frame memory to store the image signals and to transfer the image signals stored in the frame memory to the data driver. The controller controls the frame memory to store the image signals for at least two horizontal synchronization periods before they are transferred to the data driver.

Abstract translation: 一种有机发光显示器及其驱动方法，用于在运动图像的回放期间防止图像重放中断。 有机发光显示器包括：显示区域，包括用于显示图像的多个像素; 用于存储图像的图像信号的帧存储器; 用于接收图像信号以生成数据信号的数据驱动器; 用于产生扫描信号的扫描驱动器; 以及控制器，用于控制帧存储器以存储图像信号并将存储在帧存储器中的图像信号传送到数据驱动器。 控制器控制帧存储器，以将图像信号存储至少两个水平同步周期，然后再转移到数据驱动器。

公开(公告)号：US09095605B2

公开(公告)日：2015-08-04

申请号：US13234670

申请日：2011-09-16

Applicant: Moon-Hee Sung ,  Chul Joong Kim ,  Haryoung Poo ,  Young-Ki Choi ,  Il Han Lee ,  Dai-Won Yoo

Inventor： Moon-Hee Sung ,  Chul Joong Kim ,  Haryoung Poo ,  Young-Ki Choi ,  Il Han Lee ,  Dai-Won Yoo

IPC: A61K38/16 ,  A61K31/785

CPC classification number: A61K31/785 ,  A61K38/164

Abstract: The present invention relates to a pharmaceutical composition for inhibiting or preventing viral infection, which comprises an effective dose of poly-gamma-glutamic acid (γ-PGA), and more particularly, to a pharmaceutical composition, a functional food, and a feedstuff additive capable of inhibiting viral infection and preventing viral diseases, which comprise poly-gamma-glutamic acid having an infection-inhibiting effect against viruses, such as an influenza virus, inducing respiratory infection or systemic infection, as an effective ingredient.The composition containing poly-gamma-glutamic acid as an effective ingredient according to the present invention, is effective for use as an animal feedstuff additive or a pharmaceutical agent for preventing influenza virus infection and various viral diseases as well as a pharmaceutical composition and a functional food to promote human health.

Abstract translation: 本发明涉及用于抑制或预防病毒感染的药物组合物，其包含有效剂量的聚-γ-谷氨酸（γ-PGA），更具体地，涉及药物组合物，功能性食品和饲料添加剂 能够抑制病毒感染和预防病毒性疾病，其包含对病毒（例如流感病毒）诱导呼吸道感染或全身感染具有感染抑制作用的聚-γ-谷氨酸作为有效成分。 含有根据本发明的有效成分的聚-γ-谷氨酸的组合物可用作动物饲料添加剂或用于预防流感病毒感染和各种病毒性疾病的药剂以及药物组合物和功能性 食物促进人体健康。

公开(公告)号：US20120010130A1

公开(公告)日：2012-01-12

申请号：US13234670

申请日：2011-09-16

Applicant: Moon-Hee SUNG ,  Chul Joong KIM ,  Haryoung POO ,  Young-Ki CHOI ,  Il Han LEE ,  Dai-Won YOO

Inventor： Moon-Hee SUNG ,  Chul Joong KIM ,  Haryoung POO ,  Young-Ki CHOI ,  Il Han LEE ,  Dai-Won YOO

IPC: A61K38/02 ,  A61P31/12

CPC classification number: A61K31/785 ,  A61K38/164

Abstract: The present invention relates to a pharmaceutical composition for inhibiting or preventing viral infection, which comprises an effective dose of poly-gamma-glutamic acid (γ-PGA), and more particularly, to a pharmaceutical composition, a functional food, and a feedstuff additive capable of inhibiting viral infection and preventing viral diseases, which comprise poly-gamma-glutamic acid having an infection-inhibiting effect against viruses, such as an influenza virus, inducing respiratory infection or systemic infection, as an effective ingredient.The composition containing poly-gamma-glutamic acid as an effective ingredient according to the present invention, is effective for use as an animal feedstuff additive or a pharmaceutical agent for preventing influenza virus infection and various viral diseases as well as a pharmaceutical composition and a functional food to promote human health.

Abstract translation: 本发明涉及用于抑制或预防病毒感染的药物组合物，其包含有效剂量的聚-γ-谷氨酸（γ-PGA），更具体地，涉及药物组合物，功能性食品和饲料添加剂 能够抑制病毒感染和预防病毒性疾病，其包含对病毒（例如流感病毒）诱导呼吸道感染或全身感染具有感染抑制作用的聚-γ-谷氨酸作为有效成分。 含有根据本发明的有效成分的聚-γ-谷氨酸的组合物可用作动物饲料添加剂或用于预防流感病毒感染和各种病毒性疾病的药剂以及药物组合物和功能性 食物促进人体健康。

公开(公告)号：US20060199185A1

公开(公告)日：2006-09-07

申请号：US10564880

申请日：2003-12-31

Applicant: Young Song ,  Haryoung Poo ,  Moon-Hee Sung ,  Seung-Pyo Hong ,  Yoon Ho Choi ,  Kwang Kim ,  Il Han Lee ,  Je Hyun Park

Inventor： Young Song ,  Haryoung Poo ,  Moon-Hee Sung ,  Seung-Pyo Hong ,  Yoon Ho Choi ,  Kwang Kim ,  Il Han Lee ,  Je Hyun Park

IPC: C40B40/02 ,  C40B40/08 ,  C12Q1/68 ,  C12N15/74

CPC classification number: C12N15/64

Abstract: The present invention relates to a plasmid (pHCE-FOREX) functioning as both a T-vector and an expression vector, which is produced by imparting a T-vector function to an HCE promoter derived from a constitutive high-level expression vector and can express a target protein in a simple and rapid manner. Also, the present invention relates to an expression vector having the target gene inserted into the plasmid, and the expression of the target gene using the same. The plasmid of the present invention can be converted into a vector that expresses the target protein by one-step T-vector cloning in a simple and rapid manner. The plasmid converted into the expression vector does not require a re-transformation step and allows the high-level expression of the target protein only by the culturing of transformed E. coli without the addition of an expensive inducer. Thus, according to the present invention, expression plasmids for large amounts of target genes can be produced at the same time, so that the present invention will be very efficient in establishing expression systems for certain genomes and gene groups.

Abstract translation: 本发明涉及用作T载体和表达载体两者的质粒（pHCE-FOREX），其通过赋予来自组成型高水平表达载体的HCE启动子产生T载体功能而产生，并可表达 目标蛋白以简单快速的方式。 此外，本发明涉及将靶基因插入质粒的表达载体，以及使用该表达载体的靶基因的表达。 本发明的质粒可通过简单快速的一步T载体克隆转化为表达靶蛋白的载体。 转化成表达载体的质粒不需要再转化步骤，并且仅通过培养转化的大肠杆菌而不添加昂贵的诱导物才允许靶蛋白的高水平表达。 因此，根据本发明，可以同时生产大量靶基因的表达质粒，从而本发明在建立某些基因组和基因组的表达系统方面将非常有效。

公开(公告)号：US06902834B2

公开(公告)日：2005-06-07

申请号：US10691627

申请日：2003-10-24

Applicant: Il Han Lee ,  Tae Gon Kim

Inventor： Il Han Lee ,  Tae Gon Kim

IPC: H05B33/26 ,  H01L51/50 ,  H05B33/12

CPC classification number: H01L51/5231 ,  H01L51/5092 ,  Y10S428/917 ,  Y10T428/26

Abstract: An organic electroluminescent (EL) display device includes an anode, a hole transport layer formed on the anode, a light-emitting layer formed on the hole transport layer, a cathode formed on the light-emitting layer, and an electron injection layer including a metal oxide represented by formula 1 formed between the light-emitting layer and the cathode. Formula 1 is MAxMByOz, where MA denotes an alkali metal or alkali earth metal, MB is a group IV or V metal, x is a number between 1 and 2 inclusive, y is a number between 1 and 2, and z is a number between 2 and 3 inclusive.

Abstract translation: 有机电致发光（EL）显示装置包括阳极，在阳极上形成的空穴传输层，形成在空穴传输层上的发光层，形成在发光层上的阴极，以及电子注入层， 在发光层和阴极之间形成由式1表示的金属氧化物。 式1是MA表示碱金属或碱土金属，MB是IV族或V族金属 ，x是1和2之间的数字，y是1和2之间的数字，z是2和3之间的数字，包括3和3。