公开(公告)号：US06327514B1

公开(公告)日：2001-12-04

申请号：US09359592

申请日：1999-07-26

Applicant: Kensuke Hazama ,  Kalev Kask ,  Satoshi Sakai ,  Moshe Schwalb

Inventor： Kensuke Hazama ,  Kalev Kask ,  Satoshi Sakai ,  Moshe Schwalb

IPC: G06F1900

CPC classification number: G05B19/4097 ,  G05B19/4181 ,  G06K9/469 ,  G06K2209/19 ,  G06Q10/00 ,  G06Q10/06 ,  G06T7/41 ,  G06T19/20 ,  G06T2200/24 ,  G06T2207/30136 ,  G06T2219/2021 ,  Y02P90/06 ,  Y02P90/10 ,  Y02P90/20 ,  Y02P90/265 ,  Y10S707/99944

Abstract: A computer program is provided for developing a bend model of a part to be produced at an intelligent production facility. In accordance with an aspect of the disclosed program, faces of the part are detected based on initial part information, and bendlines of the part are identified based on the detected faces of the part. Further, additional part information is generated by performing a predetermined operation (e.g., a folding operation or an unfolding operation) on the detected faces of the part. The disclosed program also includes other capabilities, such as the capability to perform clean-up operations on initial, 2-D part information and to selectively eliminate part thickness representations in order to facilitate the preparation of a 3-D representation of the part from the modified 2-D part information.

Abstract translation: 提供了一种计算机程序，用于开发要在智能生产设备处产生的零件的弯曲模型。 根据所公开的程序的一个方面，基于初始部件信息检测部件的面部，并且基于检测到的部件的面部来识别部件的弯曲线。 此外，通过对部件的检测到的面进行预定的操作（例如，折叠操作或展开操作）来产生附加的部件信息。 所公开的程序还包括其他功能，例如对初始的2-D部分信息进行清理操作的能力，并且选择性地消除部分厚度表示，以便于从部件厚度表示准备3-D表示 修改后的二维零件信息。

公开(公告)号：US06542937B1

公开(公告)日：2003-04-01

申请号：US09031666

申请日：1998-02-27

Applicant: Kalev Kask ,  Dmitry Leshchiner ,  Liang Huang

Inventor： Kalev Kask ,  Dmitry Leshchiner ,  Liang Huang

IPC: G06F900

CPC classification number: G06F17/50 ,  G05B19/4097 ,  G05B2219/32153 ,  G05B2219/34256 ,  G05B2219/34262 ,  G05B2219/35005 ,  G05B2219/35012 ,  G05B2219/35155 ,  G05B2219/35192 ,  G05B2219/36203 ,  G06F2217/42 ,  Y02P90/265

Abstract: An apparatus and method are disclosed for transferring part data, such as sheet metal part data, between computer-based application or CAD environments and for editing such part data. The application environments may include a 2-D CAD program environment and an object oriented bend model program environment. An interface is provided through which a 2-D CAD system may access data from the object oriented bend model system and by which data may be transferred between the systems to permit editing and updating of the part model within and from both applications. The interface may be implemented through a library or set of application program interface (API) functions and a message-based protocol (such as dynamic data exchange (DDE)) to facilitate the exchange of sheet metal part data. Various editing capabilities or tools may also be provided to enable, for example, the attachment of faces of the part or the shifting of one face relative to another face of the part.

Abstract translation: 公开了用于在基于计算机的应用程序或CAD环境之间传送诸如钣金零件数据的零件数据并用于编辑这样的零件数据的装置和方法。 应用环境可以包括2-D CAD程序环境和面向对象的弯曲模型程序环境。 提供了一种接口，通过该接口，2-D CAD系统可以从面向对象的弯曲模型系统访问数据，并且可以在系统之间传送数据，以允许在两个应用内部和从两个应用程序编辑和更新零件模型。 接口可以通过库或一组应用程序接口（API）功能和基于消息的协议（例如动态数据交换（DDE））来实现，以便于更换钣金零件数据。 还可以提供各种编辑功能或工具，以使例如部件的面部附接或相对于部件的另一面部移动一个面部。

公开(公告)号：US06212441B1

公开(公告)日：2001-04-03

申请号：US09007182

申请日：1998-01-14

Applicant: Kensuke Hazama ,  Kalev Kask ,  Satoshi Sakai ,  Anand Heriharan Subbaraman

Inventor： Kensuke Hazama ,  Kalev Kask ,  Satoshi Sakai ,  Anand Heriharan Subbaraman

IPC: G06F1900

CPC classification number: G06T19/00 ,  G05B19/4097 ,  G05B19/4181 ,  G06Q10/06 ,  G06T7/41 ,  G06T2207/30136 ,  Y02P90/06 ,  Y02P90/265 ,  Y10S707/99944 ,  Y10S715/964

Abstract: An apparatus and method is provided for managing and distributing design and manufacturing information throughout a factory in order to facilitate the production of components, such as bent sheet metal components. In accordance with an aspect of the present invention, the management and distribution of critical design and manufacturing information is achieved by storing and distributing the design and manufacturing information associated with each job. By replacing the traditional paper job set-up or work sheet with, an electronically stored job sheet that can be accessed instantaneously from any location in the factory, the present invention improves the overall efficiency of the factory. In addition, through the various aspects and features of the invention, the organization and accessibility of part information and stored expert knowledge is improved.

Abstract translation: 提供了一种用于在整个工厂中管理和分配设计和制造信息的装置和方法，以便于生产诸如弯曲的金属板零件的部件。 根据本发明的一个方面，通过存储和分发与每个作业相关联的设计和制造信息来实现关键设计和制造信息的管理和分配。 通过用工厂中的任何位置即时访问的电子存储工作表来代替传统的纸张作业设置或工作表，本发明提高了工厂的整体效率。 另外，通过本发明的各个方面和特征，改进了部件信息的组织和可访问性以及存储的专家知识。

公开(公告)号：US5886897A

公开(公告)日：1999-03-23

申请号：US690671

申请日：1996-07-31

Applicant: Kensuke Hazama ,  Kalev Kask ,  Satoshi Sakai ,  Anand Subbaraman

Inventor： Kensuke Hazama ,  Kalev Kask ,  Satoshi Sakai ,  Anand Subbaraman

IPC: G05B19/4097 ,  G05B19/418 ,  G06Q10/06 ,  G06T7/40 ,  G06T17/00 ,  G06T19/00 ,  G06F19/00

CPC classification number: G06T19/00 ,  G05B19/4097 ,  G05B19/4181 ,  G06Q10/06 ,  G06T7/401 ,  G06T2207/30136 ,  Y02P90/06 ,  Y02P90/265 ,  Y10S707/99944 ,  Y10S715/964

Abstract: An apparatus and method is provided for managing and distributing design and manufacturing information throughout a factory in order to facilitate the production of components, such as bent sheet metal components. In accordance with an aspect of the present invention, the management and distribution of critical design and manufacturing information is achieved by storing and distributing the design and manufacturing information associated with each job. By replacing the traditional paper job set-up or work sheet with, for example, an electronically stored job sheet that can be accessed instantaneously from any location in the factory, the present invention improves the overall efficiency of the factory. In addition, through the various aspects and features of the invention, the organization and accessibility of part information and stored expert knowledge is improved.

公开(公告)号：US5971589A

公开(公告)日：1999-10-26

申请号：US700671

申请日：1996-07-31

Applicant: Kensuke Hazama ,  Kalev Kask ,  Satoshi Sakai ,  Moshe Schwalb

Inventor： Kensuke Hazama ,  Kalev Kask ,  Satoshi Sakai ,  Moshe Schwalb

IPC: G05B19/4097 ,  G05B19/418 ,  G06Q10/00 ,  G06Q10/06 ,  G06T7/40 ,  G06T17/00 ,  G06T19/00 ,  G06T19/20 ,  G06F19/00

CPC classification number: G06T7/401 ,  G05B19/4097 ,  G05B19/4181 ,  G06K9/469 ,  G06Q10/00 ,  G06Q10/06 ,  G06T19/20 ,  G06K2209/19 ,  G06T2200/24 ,  G06T2207/30136 ,  G06T2219/2021 ,  Y02P90/06 ,  Y02P90/10 ,  Y02P90/20 ,  Y02P90/265 ,  Y10S707/99944

Abstract: A system and method are provided for developing a bend model of a part to be produced at an intelligent production facility. In accordance with an aspect of the disclosed system and method, faces of the part are detected based on initial part information, and bendlines of the part are identified based on the detected faces of the part. Further, additional part information is generated by performing a predetermined operation (e.g., a folding operation or an unfolding operation) on the detected faces of the part. The disclosed system and method also include other capabilities, such as the capability to perform clean-up operations on initial, 2-D part information and to selectively eliminate part thickness representations in order to facilitate the preparation of a 3-D representation of the part from the modified 2-D part information.

Abstract translation: 提供了一种系统和方法来开发在智能生产设备上要生产的零件的弯曲模型。 根据所公开的系统和方法的一个方面，基于初始部件信息检测部件的面部，并且基于部件的检测到的面部来识别部件的弯曲线。 此外，通过对部件的检测到的面进行预定的操作（例如，折叠操作或展开操作）来产生附加的部件信息。 所公开的系统和方法还包括其他能力，例如对初始的2-D部分信息执行清理操作的能力，并且选择性地消除部分厚度表示，以便于准备部件的3-D表示 从修改后的二维零件信息。

公开(公告)号：US06660483B1

公开(公告)日：2003-12-09

申请号：US09688078

申请日：2000-10-13

Applicant: Kalev Kask ,  Thorsten Melcher ,  Daniel J. Chin

Inventor： Kalev Kask ,  Thorsten Melcher ,  Daniel J. Chin

IPC: C12Q100

CPC classification number: G01N33/573 ,  C12Q1/34 ,  G01N33/6896 ,  G01N2333/916

Abstract: The invention relates to a human phospholipase C expressed in the brain (B-PLC) and induced in response to ischemic brain tissue. The inventions provides methods and reagents useful for diagnosis and treatment of hypoxic-ischemic brain insult such as stroke.

Abstract translation: 本发明涉及在脑中表达的人类磷脂酶C（B-PLC），并且响应缺血性脑组织诱导。 本发明提供了用于诊断和治疗缺氧缺血性脑损伤如中风的方法和试剂。

公开(公告)号：US06521414B2

公开(公告)日：2003-02-18

申请号：US09774481

申请日：2001-01-30

Applicant: Thorsten Melcher ,  Kalev Kask

Inventor： Thorsten Melcher ,  Kalev Kask

IPC: G01N3353

CPC classification number: C12Q1/42 ,  G01N33/9406 ,  G01N2500/00

Abstract: The present invention relates to the identification of a binding between NMDA receptor (NMDA-R) subunits and a protein tyrosine phosphatase (PTP), e.g., PTPL1. The present invention provides methods for screening a PTPL1 agonist or antagonist that modulates NMDA-R signaling. The present invention also provide methods and compositions for treatment of disorders mediated by abnormal NMDA-R signaling. The present invention further provides methods for isolating PTPL1 from a biological preparation.

Abstract translation: 本发明涉及鉴定NMDA受体（NMDA-R）亚基与蛋白酪氨酸磷酸酶（PTP）如PTPL1之间的结合。 本发明提供了筛选调节NMDA-R信号传导的PTPL1激动剂或拮抗剂的方法。 本发明还提供了用于治疗由NMDA-R异常信号传导介导的病症的方法和组合物。 本发明还提供从生物制剂中分离PTPL1的方法。

公开(公告)号：US06411862B1

公开(公告)日：2002-06-25

申请号：US09272095

申请日：1999-03-18

Applicant: Kensuke Hazama ,  Kalev Kask ,  Satoshi Sakai ,  Anand Subbaraman

Inventor： Kensuke Hazama ,  Kalev Kask ,  Satoshi Sakai ,  Anand Subbaraman

IPC: G06F1900

CPC classification number: G06T19/00 ,  G05B19/4097 ,  G05B19/4181 ,  G06Q10/06 ,  G06T7/41 ,  G06T2207/30136 ,  Y02P90/06 ,  Y02P90/265 ,  Y10S707/99944 ,  Y10S715/964

Abstract: An apparatus and method is provided for managing and distributing design and manufacturing information throughout a factory in order to facilitate the production of components, such as bent sheet metal components. In accordance with an aspect of the present invention, the management and distribution of critical design and manufacturing information is achieved by storing and distributing the design and manufacturing information associated with each job. By replacing the traditional paper job set-up or work sheet with, for example, an electronically stored job sheet that can be accessed instantaneously from any location in the factory, the present invention improves the overall efficiency of the factory. In addition, through the various aspects and features of the invention, the organization and accessibility of part information and stored expert knowledge is improved.

Abstract translation: 提供了一种用于在整个工厂中管理和分配设计和制造信息的装置和方法，以便于生产诸如弯曲的金属板零件的部件。 根据本发明的一个方面，通过存储和分发与每个作业相关联的设计和制造信息来实现关键设计和制造信息的管理和分发。 通过用例如工厂中的任何位置即时访问的电子存储工作表来代替传统的纸张作业设置或工作表，本发明提高了工厂的整体效率。 另外，通过本发明的各个方面和特征，改进了部件信息的组织和可访问性以及存储的专家知识。

公开(公告)号：US6144896A

公开(公告)日：2000-11-07

申请号：US034401

申请日：1998-03-04

Applicant: Kalev Kask ,  Jun-Shiou Ou ,  Dmitry Leshchiner ,  Kensuke Hazama

Inventor： Kalev Kask ,  Jun-Shiou Ou ,  Dmitry Leshchiner ,  Kensuke Hazama

IPC: B21D5/01 ,  G06F17/50 ,  G06T19/00 ,  G06F19/00 ,  G05B19/4097

CPC classification number: G06T19/00 ,  G05B19/4099 ,  G05B2219/35018 ,  G05B2219/35192 ,  G06T2219/021 ,  G06T2219/2021 ,  Y02P90/265

Abstract: An apparatus is provided for resolving a collision between a first face and a second face of a sheet metal part represented by a 3-D model. The faces collide with one another when a 2-D model of a flat sheet metal part, designed on a CAD system, is folded into the 3-D model displayed on the CAD system. The apparatus comprises a detecting means, an analyzing means and an eliminating means. The detecting means is for detecting each collision between the faces which become adjacent in association with folding the 2-D model into the 3-D model. The eliminating means is for eliminating the collision by designing a 2-D model of a modified flat sheet metal part which can be folded without causing the collision.

Abstract translation: 提供一种用于解决由3D模型表示的钣金件的第一面和第二面之间的碰撞的装置。 当在CAD系统上设计的平板钣金零件的二维模型折叠成CAD系统上显示的3D模型时，两面相互碰撞。 该装置包括检测装置，分析装置和消除装置。 检测装置用于检测与将2D模型折叠成3-D模型相关联的变得相邻的面之间的每个碰撞。 消除装置是通过设计可以折叠而不引起碰撞的改进的平板金属部件的2-D模型来消除碰撞。