摘要:
The invention relates to a timer device capable of performing one or more control actions in response to the time lapsed since a user initiated action took place. The timer device comprises contact means operatable between two conditions, timer means, and means for storing first and second time stamps. The device further comprises control means for setting a first time stamp in response to the contact means being operated between first and second conditions, setting a second time stamp in response to the contact means being operated between the second and first conditions, calculating the time elapsed between the two time stamps, comparing the elapsed time with a preset time value, and performing a control action if the elapsed time is greater than the preset time value.
摘要:
In a process for producing an iron-dextran compound for use in parenteral treatment of iron-deficiency in humans or animals a stable compound of desired relatively low molecular weight is obtained by using first hydrogenation and then oxidation to convert reducing terminal groups on the dextran molecules before reaction with the iron. By varying the ratio of hydrogenated groups to oxygenated groups the average molecular weight of the resulting iron-dextran compound can be varied.
摘要:
The present invention relates to a method for improving the properties of a cellulolytic enzyme by amino acid substitution, deletion or insertion, the method comprising the steps of:a. constructing a multiple alignment of at least two amino acid sequences known to have three-dimensional structures similar to endoglucanase V (EGV) from Humicola insolens known from Protein Data Bank entry 4ENG; b. constructing a homology-built three-dimensional structure of the cellulolytic enzyme based on the structure of the EGV; c. identifying amino acid residue positions present in a distance from the substrate binding cleft of not more than 5 Å; d. identifying surface-exposed amino acid residues of the enzyme; e. identifying all charged or potentially charged amino acid residue positions of the enzyme; f. choosing one or more positions wherein the amino acid residue is to be substituted, deleted or where an insertion is to be provided; and g. carrying out the substitution, deletion or insertion by using conventional protein engineering techniques. Also described are cellulase variants obtained by this method.
摘要:
Glycosides of diacylglycerol, e.g. 3-β-D-galactopyranosyloxy-2-(octadeca-9Z,12Z,15Z-trienoyloxy)propanyl octadeca-9Z,12Z,15Z-trienoate (GOPO), which was isolated from extracts of rose-hips by activity guided fractionation, can be used as an oral anti-inflammatory agent for the treatment of inflammatory diseases such as arthritis and osteoarthrosis.
摘要:
There are provided measures for cell search and synchronization. Such measures may exemplarily comprise acquiring an observation signal for a carrier signal on a carrier which is under consideration for synchronization with a desired cellular system, calculating a power measure of the observation signal, which indicates a received power of said carrier signal, calculating a non-circularity measure of the observation signal, which indicates a non-circularity of said carrier signal, and calculating a ranking measure, which indicates an applicability of said carrier for synchronization with the desired cellular system, based on the calculated power measure and the calculated non-circularity measure.
摘要:
Toy block (1) comprising a sidewall (2) with an inner surface and an outer surface (3) intended for abutment against a surface of a corresponding toy block, said sidewall (2) comprising a through hole (4) for receipt of a catch portion (7) of a connecting element (6) and a recess (5) in said outer surface (3) adjacent the through hole (4), and said toy block (1) comprising a catch for engaging and holding the catch portion (7) of a connecting element (6), said catch being situated in the interior of the toy block (1) in a distance from said inner surface, and at least one of said recess (5) and said through hole (4) is non-circular, toy block connecting element (6) for such a toy block (1) and toy block element (11) for producing such a toy block (1).