公开(公告)号：US10595795B2

公开(公告)日：2020-03-24

申请号：US14503356

申请日：2014-09-30

申请人： Marcus Pfister

发明人： Marcus Pfister

IPC分类号： A61B6/12 ,  A61B6/03 ,  G06T7/30 ,  A61B6/00

摘要： An angiographic examination method for depicting a target region as an examination object using an angiography system includes capturing a volume data set of the target region with the examination object, registering the volume data set to a C-arm, and extracting information about an assumed course of the examination object in the volume data set. The method also includes generating a 2D projection image of a medical instrument in the target region, 2D/3D merging the 2D projection image and the registered volume data set for generating a 2D overlay image, and detecting the instrument in the 2D overlay image with a first projection matrix. The method includes generating a virtual 2D projection using a virtual projection matrix, 3D reconstructing the instrument, and distorting at least part of the reference image such that the current and the assumed course of vessels are made to be congruent.

公开(公告)号：US20180279974A1

公开(公告)日：2018-10-04

申请号：US15942992

申请日：2018-04-02

申请人： Katharina Breininger ,  Marcus Pfister

发明人： Katharina Breininger ,  Marcus Pfister

IPC分类号： A61B6/12 ,  A61B6/00

摘要： Methods and systems are provided for determining a stiffness information of a medical instrument used during a minimally invasive interventional procedure in a vascular system of a patient by recording a three-dimensional volume image of the vascular system at least in the intervention region.

公开(公告)号：US08219183B2

公开(公告)日：2012-07-10

申请号：US11977110

申请日：2007-10-23

申请人： Michael Maschke ,  Marcus Pfister

发明人： Michael Maschke ,  Marcus Pfister

IPC分类号： A61B6/00

CPC分类号： A61B5/6852 ,  A61B5/0066 ,  A61B5/02007 ,  A61B5/7425

摘要： A generation of sectional images of tissue is provided. In this arrangement a first light-conducting fiber of a device for generating sectional tissue images according to the optical coherence tomography principle, which light-conducting fiber is rotatably accommodated within a catheter tube, is additionally connected to a device for generating light in a further wavelength range and for detecting fluorescent light. With its use sectional tissue images produced according to the optical coherence tomography principle can be superimposed with fluorescent images.

摘要翻译： 提供了一代组织的剖面图像。 在这种布置中，用于根据光学相干断层摄影原理产生部分组织图像的装置的第一导光纤维，该光学相干断层摄影原理将导光纤维可旋转地容纳在导管内，另外连接到用于产生光的装置 波长范围和用于检测荧光灯。 使用根据光学相干断层摄影原理产生的截面组织图像可以与荧光图像叠加。

公开(公告)号：US20120089003A1

公开(公告)日：2012-04-12

申请号：US12900082

申请日：2010-10-07

申请人： Martin Ostermeier ,  Marcus Pfister

发明人： Martin Ostermeier ,  Marcus Pfister

IPC分类号： A61B5/05

CPC分类号： A61B6/5223 ,  A61B6/032 ,  A61B6/12 ,  A61B6/4085 ,  A61B6/4441 ,  A61B6/487 ,  A61B6/488 ,  A61B6/504 ,  A61B6/5235 ,  A61F2/95 ,  G06T15/08 ,  G06T19/00 ,  G06T2210/41 ,  G06T2215/06

摘要： In a method for a fluoroscopy controlled insertion of a stent into a curved aorta of a patient for aneurysm repair, a 3D volume image is obtained of the patient's aorta at the aneurysm. By knowing a registration of the 3D volume image to a C-arm of an angiographic system and projection geometry of the angiography system, the 3D volume images are projected atomically correct to a 2D fluoroscopy image of the angiography system. For the 2D3D overlay, the 3D volume image is displayed as a curved planar reconstruction in which the 2D fluoroscopy image and the 3D volume image are warped around a curved center line of the patient's curved aorta or around a curved guide instrument center line to correct for the curvature of the aorta so that the previously curved aorta center line or curved center line of the guide instrument turns into a straight line. The 2D3D overlay is used to visualize the insertion of the stent.

摘要翻译： 在用于荧光透视的控制性插入支架到用于动脉瘤修复的患者的弯曲主动脉中的方法中，获得了动脉瘤患者主动脉的3D体积图像。 通过将3D体积图像注册到血管造影系统的C臂和血管造影系统的投影几何结构，3D体积图像被投影原子校正到血管造影系统的2D透视图像。 对于2D3D叠加，3D体积图像被显示为弯曲平面重建，其中2D透视图像和3D体积图像围绕患者弯曲主动脉的弯曲中心线或围绕弯曲导向仪器中心线扭曲，以校正 主动脉的曲率，使得导向仪器的先前弯曲的主动脉中心线或弯曲的中心线变成直线。 2D3D叠层用于可视化支架的插入。

公开(公告)号：US08041095B2

公开(公告)日：2011-10-18

申请号：US12136862

申请日：2008-06-11

申请人： Ashraf Mohamed ,  Marcus Pfister

发明人： Ashraf Mohamed ,  Marcus Pfister

IPC分类号： G06K9/00 ,  G06K9/46 ,  G06K9/52

CPC分类号： A61B17/12022 ,  A61B5/02007 ,  A61B5/1076 ,  A61B6/4441 ,  A61B6/504 ,  A61B17/12118 ,  A61B17/1214 ,  A61B2017/00712 ,  A61B2017/00725 ,  G06T7/62 ,  G06T17/00 ,  G06T2207/10072 ,  G06T2207/30016 ,  G06T2207/30101

摘要： The present invention relates to a method and apparatus for pretreatment planning endovascular coil placement, comprising steps of: a) analyzing three-dimensional data enabling visualization of a volume of interest containing at least a part of a blood vessel with an aneurysm; b) determining the centerline of the vessel; c) determining the aneurysm diameter; d) determining the aneurysm dome height; e) creating a three-dimensional surface model of the aneurysm in the vessel, using the results from the previous steps; f) estimating the volume expansion of one or more coils with the aid of said surface model; and g) visual simulating at least one according to the estimated virtual coil being to place inside the aneurysm.

摘要翻译： 本发明涉及一种用于预处理规划血管内线圈放置的方法和装置，包括以下步骤：a）分析能够使包含至少一部分具有动脉瘤的血管的感兴趣体积的可视化的三维数据; b）确定船只的中心线; c）确定动脉瘤直径; d）确定动脉瘤圆顶高度; e）使用前面步骤的结果创建血管内动脉瘤的三维表面模型; f）借助于所述表面模型估计一个或多个线圈的体积膨胀; 以及g）根据估计的虚拟线圈将至少一个放置在动脉瘤内部的视觉模拟。

公开(公告)号：US20110064189A1

公开(公告)日：2011-03-17

申请号：US12880319

申请日：2010-09-13

申请人： Peng Wang ,  Marcus Pfister ,  Terrence Chen ,  Martin Ostermeier ,  Dorin Comaniciu

发明人： Peng Wang ,  Marcus Pfister ,  Terrence Chen ,  Martin Ostermeier ,  Dorin Comaniciu

IPC分类号： A61B6/02

CPC分类号： A61B6/12

摘要： A method and system for tracking a needle in a fluoroscopic image sequence is disclosed. In order to track a needle in a fluoroscopic image sequence, the needle is initialized in a first frame of the fluoroscopic image sequence. Needle segments are detected in each subsequent frame of the fluoroscopic image sequence, and the needle is detected in each frame of the fluoroscopic image by tracking the needle from a previous frame of the fluoroscopic image sequence based on the detected needle segments in the current frame.

摘要翻译： 公开了一种用于在荧光镜像图像序列中跟踪针的方法和系统。 为了在透视图像序列中跟踪针，在荧光镜图像序列的第一帧中初始化针。 在透视图像序列的每个随后的帧中检测针段，并且基于当前帧中检测到的针段，通过从荧光透视图像序列的先前帧跟踪针来在荧光镜图像的每个帧中检测针。

公开(公告)号：US20100240970A1

公开(公告)日：2010-09-23

申请号：US12723940

申请日：2010-03-15

申请人： Arne HENGERER ,  Andreas Kappel ,  Luis Lasalvia ,  Andrea Lichte ,  Thomas Mertelmeier ,  Sven Meyburg ,  Christoph Petry ,  Marcus Pfister ,  Martin Requardt

发明人： Arne HENGERER ,  Andreas Kappel ,  Luis Lasalvia ,  Andrea Lichte ,  Thomas Mertelmeier ,  Sven Meyburg ,  Christoph Petry ,  Marcus Pfister ,  Martin Requardt

IPC分类号： A61B5/145 ,  A61M31/00

CPC分类号： A61B5/0002 ,  A61B5/14503 ,  A61B5/4839 ,  A61B10/0045

摘要： An embodiment of the present invention relates to a device, which can be implanted into a patient, for an in vivo measurement. In an embodiment, the device includes a catheter for guiding a sample of the patient town analysis unit in the device. A measurement result is determined in the analysis unit by analyzing the sample with the aid of a reagent. In an embodiment, the device furthermore includes an interchange chamber, with the aid of which the reagent can be removed from the device or can be inserted into the device. The interchange chamber has a connector allowing removal or insertion of the reagent while the device is implanted.

摘要翻译： 本发明的一个实施例涉及可以植入患者体内的用于体内测量的装置。 在一个实施例中，该装置包括用于引导装置中的患者镇分析单元的样本的导管。 借助于试剂分析样品，在分析单元中测定​​结果。 在一个实施方案中，该装置还包括一个互换室，借助于此可以将该试剂从该装置中移除或者可插入该装置中。 交换室具有连接器，其允许在植入装置时移除或插入试剂。

公开(公告)号：US07706854B2

公开(公告)日：2010-04-27

申请号：US11410631

申请日：2006-04-25

申请人： Martin Kleen ,  Marcus Pfister

发明人： Martin Kleen ,  Marcus Pfister

IPC分类号： A61B5/05

CPC分类号： A61B5/6852 ,  A61B5/0066 ,  A61B5/0073

摘要： In order to improve the quality of cross-sectional images, which have been recorded along a longitudinal axis of a vessel of a body, it is proposed to add successive cross-sectional images to an overall cross-sectional image. Artifacts in the cross-sectional images are hereby weakened and pathological structures to be detected are high-lighted.

摘要翻译： 为了提高沿着身体的血管的纵轴记录的横截面图像的质量，建议将连续的横截面图像添加到整个横截面图像。 因此，横截面图像中的人造物被削弱，并且待检测的病理结构被高光照射。

公开(公告)号：US07657069B2

公开(公告)日：2010-02-02

申请号：US11076537

申请日：2005-03-08

申请人： Jan Boese ,  Martin Kleen ,  Marcus Pfister ,  Norbert Rahn

发明人： Jan Boese ,  Martin Kleen ,  Marcus Pfister ,  Norbert Rahn

IPC分类号： G06K9/00

CPC分类号： A61B5/06 ,  A61B5/0073 ,  A61B5/0084 ,  A61B5/7207 ,  A61B5/7289 ,  A61B8/12 ,  A61B8/5238

摘要： The present invention relates to a method for imaging using an image-generating, endoluminal instrument (1) by means of which a sequence of 2D image data of a hollow channel (2), in particular a vessel, of an object under investigation is recorded, wherein the images are recorded in a known temporal relation to a periodic movement of the object under investigation and spatial coordinates of the image are captured by means of a position sensor during each recording of an image (5) and stored as position data (9, 10) together with the 2D image data of the image (5). The method is characterized in that first position data (10) which does not lie in a predefinable movement phase of the object under investigation is corrected, before or after being stored, by interpolation between second position data (9) which does lie in the specified movement phase and/or by subtraction or addition of predetermined values. By means of the method a movement correction of the data can be performed without the need to reduce the volume of recorded image material.

摘要翻译： 本发明涉及一种使用图像生成的腔内器械（1）进行成像的方法，通过该方法，记录被调查对象的空心通道（2），特别是血管的2D图像数据的序列 ，其中图像以已知的时间关系记录在被调查对象的周期性运动中，并且在每次记录图像（5）期间通过位置传感器捕获图像的空间坐标，并将其存储为位置数据（9） ，10）与图像（5）的2D图像数据一起。 该方法的特征在于，通过在位于指定的位置的第二位置数据（9）之间的内插来校正不在被调查对象的预定义移动阶段的第一位置数据（10），在存储之前或之后， 移动阶段和/或通过减去或添加预定值。 通过该方法，可以执行数据的移动校正，而不需要减少记录的图像材料的体积。

公开(公告)号：US20090274271A1

公开(公告)日：2009-11-05

申请号：US12431518

申请日：2009-04-28

申请人： Marcus Pfister ,  Norbert Strobel

发明人： Marcus Pfister ,  Norbert Strobel

IPC分类号： G01N23/04 ,  A61N5/10 ,  A61B6/08

CPC分类号： A61B6/12 ,  A61B6/4441 ,  A61B6/5229 ,  A61B90/11 ,  A61B90/13 ,  A61B2034/107 ,  A61B2090/364 ,  A61B2090/376 ,  A61N2005/1061 ,  G06F19/00

摘要： A system and method are disclosed for planning a percutaneous procedure and for guiding an instrument to engage a target within a patient's body. A patient 3-dimensional image data set is provided, within which a user defines an instrument trajectory, for example, by selecting a skin entry point and a target point. A line, or “planned path,” is generated between the points. The system determines whether the path can be targeted so the optical axis of the movable arm coincides with the path so that a laser can be used for instrument guidance. Alternatively, the user can determine whether planned path can be targeted so that the C-arm can be made to coincide with the path so that the extension of the path is projected onto the detector, using x-ray radiation. If neither laser guidance or x-ray guidance can be used, the physician is prompted to re-plan the path so that at least x-ray radiation guidance can be used. Once the desired guidance method is selected, the puncture instrument is guided along the planned path to engage the target.

摘要翻译： 公开了一种用于规划经皮程序和引导器械使患者身体内的目标接合的系统和方法。 提供了一种患者的三维图像数据集，其中用户通过选择皮肤入口点和目标点来定义仪器轨迹。 点之间产生一行或“计划路径”。 系统确定路径是否可以被定向，使可动臂的光轴与路径重合，使得激光可以用于仪器引导。 或者，用户可以确定是否可以定向计划的路径，使得C臂可以与路径一致，使得使用x射线辐射将路径的延伸投影到检测器上。 如果既不能使用激光引导或X射线引导，也可以提示医生重新规划路径，以至少可以使用x射线辐射引导。 一旦选择了所需的引导方法，穿刺器械沿着规划的路径被引导以接合目标。