公开(公告)号：US08476047B2

公开(公告)日：2013-07-02

申请号：US13692254

申请日：2012-12-03

Applicant: Keith H. Burlew ,  Robert Dicosimo ,  Michael Charles Grady

Inventor： Keith H. Burlew ,  Robert Dicosimo ,  Michael Charles Grady

IPC: C12P7/02 ,  C12P7/16

CPC classification number: C12P7/16 ,  A23K10/38 ,  B01D3/002 ,  B01D11/0492 ,  B01D21/26 ,  B01D21/262 ,  C07C29/86 ,  C11B1/025 ,  C11B13/00 ,  C12F3/10 ,  C12M1/00 ,  C12M21/12 ,  C12M45/04 ,  C12M45/09 ,  C12N1/14 ,  C12N15/00 ,  C12P7/18 ,  C12P7/6418 ,  Y02E50/10 ,  Y02E50/16 ,  Y02E50/17 ,  Y02W30/74

Abstract: In an alcohol fermentation process, oil derived from biomass is hydrolyzed into an extractant available for in situ removal of a product alcohol such as butanol from a fermentation broth. The glycerides in the oil can be catalytically (e.g., enzymatically) hydrolyzed into free fatty acids, which form a fermentation product extractant having a partition coefficient for a product alcohol greater than a partition coefficient of the oil of the biomass for the product alcohol. Oil derived from a feedstock of an alcohol fermentation process can be hydrolyzed by contacting the feedstock including the oil with one or more enzymes whereby at least a portion of the oil is hydrolyzed into free fatty acids forming a fermentation product extractant, or the oil can be separated from the feedstock prior to the feedstock being fed to a fermentation vessel, and the separated oil can be contacted with the enzymes to form the fermentation product extractant. The fermentation product extractant can be contacted with a fermentation broth for in situ removal of a product alcohol.

Abstract translation: 在酒精发酵过程中，将来自生物质的油水解成可从发酵液中原位除去产物醇如丁醇的萃取剂。 油中的甘油酯可以催化（例如，酶促）水解成游离脂肪酸，其形成产物醇的分配系数大于产物醇的生物质油的分配系数的发酵产物萃取剂。 由酒精发酵方法的原料得到的油可以通过使包含油的原料与一种或多种酶接触来水解，由此至少一部分油被水解成形成发酵产物萃取剂的游离脂肪酸，或者油可以是 在原料进料到发酵容器之前与原料分离，并且分离的油可以与酶接触以形成发酵产物萃取剂。 发酵产物萃取剂可与发酵液接触，用于原位除去产物醇。

公开(公告)号：US20120208246A1

公开(公告)日：2012-08-16

申请号：US13193147

申请日：2011-07-28

Applicant: Douglas Robert Anton ,  Stephane Francois Bazzana ,  Keith H. Burlew ,  Jelena Cirakovic ,  Robert Dicosimo ,  Bruce A. Diner ,  Michael Charles Grady ,  Brian Michael Roesch ,  Francis J. Woerner

Inventor： Douglas Robert Anton ,  Stephane Francois Bazzana ,  Keith H. Burlew ,  Jelena Cirakovic ,  Robert Dicosimo ,  Bruce A. Diner ,  Michael Charles Grady ,  Brian Michael Roesch ,  Francis J. Woerner

IPC: C12P7/64 ,  C12N9/16 ,  A23K1/06 ,  C12P7/16

CPC classification number: A23K1/007 ,  A23K10/12 ,  A23K10/38 ,  C12P7/16 ,  C12P7/62 ,  C12P7/649 ,  C12P2203/00 ,  Y02E50/10 ,  Y02E50/13 ,  Y02P60/873

Abstract: An alcohol fermentation process and composition that includes production of alcohol esters by esterification of product alcohol in a fermentation medium with a carboxylic acid (e.g., fatty acid) and a catalyst (e.g., lipase) capable of esterifying the product alcohol, such as butanol, with the carboxylic acid to form the alcohol esters. The alcohol esters can be extracted from the fermentation medium, and the product alcohol recovered from the alcohol esters. The carboxylic acid can also serve as an extractant for removal of the alcohol esters from the fermentation medium.

Abstract translation: 醇发酵方法和组合物，其包括通过在发酵培养基中与产物醇与羧酸（例如，脂肪酸）和能够酯化产物醇（例如丁醇）的催化剂（例如脂肪酶）酯化产生醇酯， 与羧酸形成醇酯。 醇酯可以​​从发酵培养基中提取，并从醇酯中回收产物醇。 羧酸也可以用作从发酵培养基中除去醇酯的提取剂。

公开(公告)号：US20120035398A1

公开(公告)日：2012-02-09

申请号：US13023134

申请日：2011-02-08

Applicant: Michael Charles Grady ,  William D. Parten ,  Robert W. Sylvester ,  Joseph J. Zaher

Inventor： Michael Charles Grady ,  William D. Parten ,  Robert W. Sylvester ,  Joseph J. Zaher

IPC: C07C31/12 ,  B01D3/10 ,  B01D3/34

CPC classification number: C07C29/80 ,  B01D3/002 ,  B01D53/1475 ,  B01D53/1487 ,  B01D2251/306 ,  B01D2251/606 ,  B01D2252/2025 ,  B01D2252/20484 ,  B01D2252/20489 ,  B01D2257/504 ,  B01D2257/704 ,  B01D2257/708 ,  B01D2257/80 ,  C07C29/76 ,  Y02C10/06 ,  Y02P20/152 ,  Y02P70/34 ,  C07C31/12

Abstract: A fermentation liquid feed including water and a product alcohol and optionally CO2 is at least partially vaporized such that a vapor stream is produced. The vapor stream is contacted with an absorption liquid under suitable conditions wherein an amount of the product alcohol is absorbed. The portion of the vapor stream that is absorbed can include an amount of each of the water, the product alcohol and optionally the CO2. The temperature at the onset of the absorption of the vapor stream into the absorption liquid can be greater than the temperature at the onset of condensation of the vapor stream in the absence of the absorption liquid. The product alcohol can be separated from the absorption liquid whereby the absorption liquid is regenerated. The absorption liquid can include a water soluble organic molecule such as an amine.

Abstract translation: 包括水和产物醇和任选的CO 2的发酵液体进料至少部分蒸发，使得产生蒸汽流。 在合适的条件下，蒸气流与吸收液体接触，其中产物醇的量被吸收。 被吸收的蒸汽流的部分可以包括一定量的水，产物醇和任选的CO 2。 蒸汽流吸收到吸收液体中开始吸收的温度可以大于在不存在吸收液体的情况下蒸气流冷凝开始时的温度。 可以将产物醇与吸收液分离，由此吸收液体被再生。 吸收液体可以包括水溶性有机分子如胺。

公开(公告)号：US20110312043A1

公开(公告)日：2011-12-22

申请号：US13162643

申请日：2011-06-17

Applicant: KEITH H. BURLEW ,  ROBERT DICOSIMO ,  MICHAEL CHARLES GRADY

Inventor： KEITH H. BURLEW ,  ROBERT DICOSIMO ,  MICHAEL CHARLES GRADY

IPC: C12P7/16 ,  C12P7/64 ,  C12P13/02 ,  C12N9/18 ,  C12P7/40 ,  C12P7/62 ,  C12N9/16 ,  C12N9/20 ,  C12P1/00 ,  C12P7/02

CPC classification number: C12P7/16 ,  A23K10/38 ,  B01D3/002 ,  B01D11/0492 ,  B01D21/26 ,  B01D21/262 ,  C07C29/86 ,  C11B1/025 ,  C11B13/00 ,  C12F3/10 ,  C12M1/00 ,  C12M21/12 ,  C12M45/04 ,  C12M45/09 ,  C12N1/14 ,  C12N15/00 ,  C12P7/18 ,  C12P7/6418 ,  Y02E50/10 ,  Y02E50/16 ,  Y02E50/17 ,  Y02W30/74

Abstract: In an alcohol fermentation process, oil derived from biomass is hydrolyzed into an extractant available for in situ removal of a product alcohol such as butanol from a fermentation broth. The glycerides in the oil can be catalytically (e.g., enzymatically) hydrolyzed into free fatty acids, which form a fermentation product extractant having a partition coefficient for a product alcohol greater than a partition coefficient of the oil of the biomass for the product alcohol. Oil derived from a feedstock of an alcohol fermentation process can be hydrolyzed by contacting the feedstock including the oil with one or more enzymes whereby at least a portion of the oil is hydrolyzed into free fatty acids forming a fermentation product extractant, or the oil can be separated from the feedstock prior to the feedstock being fed to a fermentation vessel, and the separated oil can be contacted with the enzymes to form the fermentation product extractant. The fermentation product extractant can be contacted with a fermentation broth for in situ removal of a product alcohol.

Abstract translation: 在酒精发酵过程中，将来自生物质的油水解成可从发酵液中原位除去产物醇如丁醇的萃取剂。 油中的甘油酯可以催化（例如，酶促）水解成游离脂肪酸，其形成产物醇的分配系数大于产物醇的生物质油的分配系数的发酵产物萃取剂。 由酒精发酵工艺的原料得到的油可以通过使包含油的原料与一种或多种酶接触来水解，由此至少一部分油被水解成形成发酵产物萃取剂的游离脂肪酸，或者油可以是 在原料进料到发酵容器之前与原料分离，并且分离的油可以与酶接触以形成发酵产物萃取剂。 发酵产物萃取剂可与发酵液接触，用于原位除去产物醇。

公开(公告)号：US20110288344A1

公开(公告)日：2011-11-24

申请号：US12948945

申请日：2010-11-18

Applicant: MICHAEL CHARLES GRADY ,  William D. Parten ,  Bruce Vrana ,  Yihui Tom Xu

Inventor： MICHAEL CHARLES GRADY ,  William D. Parten ,  Bruce Vrana ,  Yihui Tom Xu

IPC: C07C29/84

CPC classification number: C12P7/16 ,  C07C29/86 ,  Y02E50/10 ,  C07C31/12

Abstract: A process for recovering butanol from a mixture comprising a water-immiscible organic extractant, water, butanol, and optionally a non-condensable gas, is provided. The butanol is selected from 1-butanol, 2-butanol, isobutanol, and mixtures thereof. An overhead stream from a first distillation column is condensed to recover a mixed condensate. An entrainer is added to at least one appropriate process stream or vessel such that the mixed condensate comprises sufficient entrainer to provide phase separation of the organic and the aqueous phases to provide for recovery of the butanol.

Abstract translation: 提供了一种从包含与水不混溶的有机萃取剂，水，丁醇和任选的不可冷凝气体的混合物中回收丁醇的方法。 丁醇选自1-丁醇，2-丁醇，异丁醇及其混合物。 将来自第一蒸馏塔的塔顶物流冷凝以回收混合的冷凝物。 将夹带剂加入到至少一个合适的工艺流或容器中，使得混合的冷凝物包含足够的夹带剂以提供有机相和水相的相分离以提供丁醇的回收。

公开(公告)号：US07897676B1

公开(公告)日：2011-03-01

申请号：US12945935

申请日：2010-11-15

Applicant: Robert John Barsotti ,  Laura Ann Lewin ,  Carl Brent Douglas ,  Michael Charles Grady ,  Donald Albert Paquet, Jr.

Inventor： Robert John Barsotti ,  Laura Ann Lewin ,  Carl Brent Douglas ,  Michael Charles Grady ,  Donald Albert Paquet, Jr.

IPC: C08G18/42 ,  C08G18/08 ,  C08L83/00 ,  C08L51/00 ,  C08F290/06 ,  C08F220/06 ,  C08F283/00 ,  C08F8/30 ,  C08C19/00

CPC classification number: C08K5/0025 ,  C08F2/001 ,  C08F2/06 ,  C08F8/30 ,  C08F2800/20 ,  C08G18/6229 ,  C08G18/792 ,  C08L79/00 ,  C08L2312/00 ,  C09D133/04 ,  C09D133/14 ,  C08L33/06 ,  C08L2666/20 ,  C08F2220/1866

Abstract: The present invention is directed to two component coating compositions that cure under ambient conditions and more particularly to those having low VOC (volatile organic content) that are suitable for use in automotive refinish and Original Equipment Manufacturing (OEM) applications. The coating composition includes crosslinkable and crosslinking components, wherein the crosslinkable component includes a low polydispersity, low molecular weight copolymer having on an average 2 to 25 functional groups, such as hydroxyl, carboxyl, acetoacetoxy, primary and secondary amine, and epoxy. The copolymer is polymerized from a monomer mixture that includes one or more non-functional acrylate monomers and one or more functional methacrylate monomers provided with the functional groups. The crosslinking component includes polyisocyanate, polyamine, ketimine, melamine, epoxy, polyacid or a combination thereof. The invention is also directed to coating produced from the coating composition.

Abstract translation: 本发明涉及在环境条件下固化的二组分涂料组合物，更具体地涉及适用于汽车修补漆和原始设备制造（OEM）应用的具有低VOC（挥发性有机物含量）的组分涂料组合物。 涂料组合物包括可交联和交联组分，其中可交联组分包括具有平均2至25个官能团的低分子量低分子量共聚物，例如羟基，羧基，乙酰乙酰氧基，伯胺和仲胺和环氧基。 共聚物由包括一种或多种非官能丙烯酸酯单体和一个或多个配有官能团的官能甲基丙烯酸酯单体的单体混合物聚合。 交联组分包括多异氰酸酯，多胺，酮亚胺，三聚氰胺，环氧树脂，多元酸或它们的组合。 本发明还涉及由涂料组合物制备的涂料。

公开(公告)号：US06989421B2

公开(公告)日：2006-01-24

申请号：US10612495

申请日：2003-07-02

Applicant: Michael Charles Grady

Inventor： Michael Charles Grady

IPC: C08F8/30

CPC classification number: C09D133/14 ,  B05D3/0254 ,  B05D7/16 ,  C08G18/6229 ,  C08G18/792 ,  C08L2312/00 ,  C09D175/04 ,  C08L2666/20 ,  C08L2666/02

Abstract: The present invention is directed to two component coating compositions that cure under ambient conditions and more particularly to those having low VOC (volatile organic content) that are suitable for use in automotive refinish and Original Equipment Manufacturing (OEM) applications. The coating composition includes crosslinkable and crosslinking components, wherein the crosslinkable component includes a low polydispersity, low molecular weight copolymer having on an average 2 to 25 crosslinkable functional groups, such as hydroxyl, acetoacetoxy, carboxyl, epoxy, primary amine and secondary amine. The copolymer is polymerized from a monomer mixture that includes one or more non-functional methacrylate monomers and one or more functional acrylate monomers provided with the functional groups. The crosslinking component includes polyisocyanate, polyamine, epoxy, polyacid, ketimine, melamine, or a combination thereof. The invention is also directed to coating produced from the coating composition.

Abstract translation: 本发明涉及在环境条件下固化的二组分涂料组合物，更具体地涉及适用于汽车修补漆和原始设备制造（OEM）应用的具有低VOC（挥发性有机物含量）的组分涂料组合物。 涂料组合物包括可交联和交联组分，其中可交联组分包括具有平均2至25个可交联官能团的低分子量低分子量共聚物，例如羟基，乙酰乙酰氧基，羧基，环氧基，伯胺和仲胺。 共聚物由包含一种或多种非官能的甲基丙烯酸酯单体和一个或多个提供有官能团的官能丙烯酸酯单体的单体混合物聚合。 交联组分包括多异氰酸酯，多胺，环氧，多酸，酮亚胺，三聚氰胺或其组合。 本发明还涉及由涂料组合物制备的涂料。

公开(公告)号：US08563788B2

公开(公告)日：2013-10-22

申请号：US13611125

申请日：2012-09-12

Applicant: Michael Charles Grady ,  William D Parten ,  Bruce M Vrana ,  Yihui Tom Xu ,  Joseph J Zaher

Inventor： Michael Charles Grady ,  William D Parten ,  Bruce M Vrana ,  Yihui Tom Xu ,  Joseph J Zaher

IPC: C07C29/80 ,  C07C29/84

CPC classification number: C12P7/16 ,  C07C29/80 ,  Y02E50/10 ,  C07C31/12

Abstract: A process for recovering butanol from a mixture comprising a water-immiscible organic extractant, water, butanol, and optionally a non-condensable gas, is provided. The butanol is selected from 1-butanol, 2-butanol, isobutanol, and mixtures thereof. The extractant comprises at least one solvent selected from the group consisting of C7 to C22 fatty alcohols, C7 to C22 fatty acids, esters of C7 to C22 fatty acids, C7 to C22 fatty aldehydes, and mixtures thereof.

公开(公告)号：US20130089900A1

公开(公告)日：2013-04-11

申请号：US13692254

申请日：2012-12-03

Applicant: Keith H. Burlew ,  Robert Dicosimo ,  Michael Charles Grady

Inventor： Keith H. Burlew ,  Robert Dicosimo ,  Michael Charles Grady

IPC: C12P7/16

CPC classification number: C12P7/16 ,  A23K10/38 ,  B01D3/002 ,  B01D11/0492 ,  B01D21/26 ,  B01D21/262 ,  C07C29/86 ,  C11B1/025 ,  C11B13/00 ,  C12F3/10 ,  C12M1/00 ,  C12M21/12 ,  C12M45/04 ,  C12M45/09 ,  C12N1/14 ,  C12N15/00 ,  C12P7/18 ,  C12P7/6418 ,  Y02E50/10 ,  Y02E50/16 ,  Y02E50/17 ,  Y02W30/74

Abstract: In an alcohol fermentation process, oil derived from biomass is hydrolyzed into an extractant available for in situ removal of a product alcohol such as butanol from a fermentation broth. The glycerides in the oil can be catalytically (e.g., enzymatically) hydrolyzed into free fatty acids, which form a fermentation product extractant having a partition coefficient for a product alcohol greater than a partition coefficient of the oil of the biomass for the product alcohol. Oil derived from a feedstock of an alcohol fermentation process can be hydrolyzed by contacting the feedstock including the oil with one or more enzymes whereby at least a portion of the oil is hydrolyzed into free fatty acids forming a fermentation product extractant, or the oil can be separated from the feedstock prior to the feedstock being fed to a fermentation vessel, and the separated oil can be contacted with the enzymes to form the fermentation product extractant. The fermentation product extractant can be contacted with a fermentation broth for in situ removal of a product alcohol.

公开(公告)号：US20130001062A1

公开(公告)日：2013-01-03

申请号：US13611125

申请日：2012-09-12

Applicant: MICHAEL CHARLES GRADY ,  William D. Parten ,  Bruce M. Vrana ,  Yihui Tom Xu ,  Joseph J. Zaher

Inventor： MICHAEL CHARLES GRADY ,  William D. Parten ,  Bruce M. Vrana ,  Yihui Tom Xu ,  Joseph J. Zaher

IPC: C07C29/84 ,  B01D3/14

CPC classification number: C12P7/16 ,  C07C29/80 ,  Y02E50/10 ,  C07C31/12

Abstract: A process for recovering butanol from a mixture comprising a water-immiscible organic extractant, water, butanol, and optionally a non-condensable gas, is provided. The butanol is selected from 1-butanol, 2-butanol, isobutanol, and mixtures thereof. The extractant comprises at least one solvent selected from the group consisting of C7 to C22 fatty alcohols, C7 to C22 fatty acids, esters of C7 to C22 fatty acids, C7 to C22 fatty aldehydes, and mixtures thereof.

Abstract translation: 提供了一种从包含与水不混溶的有机萃取剂，水，丁醇和任选的不可冷凝气体的混合物中回收丁醇的方法。 丁醇选自1-丁醇，2-丁醇，异丁醇及其混合物。 萃取剂包含至少一种选自C7至C22脂肪醇，C7至C22脂肪酸，C7至C22脂肪酸酯，C7至C22脂肪醛及其混合物的溶剂。