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    Anti-fungal agent
    1.
    发明授权
    Anti-fungal agent 有权

    公开(公告)号：US12121512B2

    公开(公告)日：2024-10-22

    申请号：US17602139

    申请日：2020-04-06

    申请人： SEREN PHARMACEUTICALS INC. ,  NIHON UNIVERSITY

    发明人： Rui Kano ,  Osamu Ogawa

    IPC分类号： A61K31/427 ,  A61P31/10

    CPC分类号： A61K31/427 ,  A61P31/10

    摘要： An object of the present invention is to provide an antifungal agent which is effective against cryptococcosis. The present invention provides an antifungal agent comprising ravuconazole as an active ingredient, wherein the agent is administered to an animal suffering from cryptococcosis. Further, the present invention provides an antifungal agent comprising ravuconazole as an active ingredient, wherein the agent is administered to an animal suffering from cryptococcus that is resistant to triazole-based antifungal agents selected from the group consisting of fluconazole, itraconazole and voriconazole.

    REVERSE PHOTOCHROMIC COMPOUND
    3.
    发明申请
    REVERSE PHOTOCHROMIC COMPOUND 审中-公开

    公开(公告)号：US20190382654A1

    公开(公告)日：2019-12-19

    申请号：US16477469

    申请日：2018-01-31

    申请人： FUJIFILM Wako Pure Chemical Corporation ,  NIHON UNIVERSITY

    发明人： Ryuzi KATOH ,  Masami ENOKI ,  Kazuki NEMOTO ,  Katsufumi SUZUKI ,  Tetsuji MURASE ,  Shigeaki IMAZEKI

    IPC分类号： C09K9/02 ,  C07D405/06 ,  C08F20/36

    摘要： A reverse photochromic compound of the related art has difficulty in sensing light with a wavelength of 600 nm or greater in a visible light region which has been used for medical applications. Therefore, an object of the present invention is to provide a reverse photochromic compound and a polymer which have a high sensitivity to light having a wavelength of 600 nm or greater.The present invention relates to a compound and the like represented by the following general formula (1). (In the formula, R1 and R4 each independently represent a hydrogen atom or the like, R2, R3, and R5 each independently represent an alkyl group or the like, R6 represents a group having a polymerizable unsaturated group, a carboxy group, or an alkoxycarbonyl group, R31 and R32 each independently represent an alkoxy group or the like, R33 and R34 each independently represent a hydrogen atom or the like, Y1 represents an oxygen atom or a sulfur atom, An− represents an anion, n1 to n3 represent a specific integer, and R1 and R2, R3 and R4, and/or R33 and R34 may form an alkylene group.)

    Magnetized Coaxial Plasma Generation Device
    8.
    发明申请
    Magnetized Coaxial Plasma Generation Device 有权
    磁化同轴等离子体发生装置

    公开(公告)号：US20160374188A1

    公开(公告)日：2016-12-22

    申请号：US14902477

    申请日：2014-06-30

    申请人： NIHON UNIVERSITY

    发明人： Tomohiko Asai ,  Jun'ichi Sekiguchi ,  Tadafumi Matsumoto

    IPC分类号： H05H1/12 ,  H05H1/48

    CPC分类号： H05H1/12 ,  H05H1/02 ,  H05H1/24 ,  H05H1/46 ,  H05H1/48 ,  H05H2001/466

    摘要： Provided is a magnetized coaxial plasma generation device having increased magnetization efficiency and capable of improving power conservation and reducing the thermal load on a coil. The magnetized coaxial plasma generation device generating spheromak plasma comprises: an external electrode (1); an internal electrode (2); a plasma generation gas supply section (3); a power supply circuit (4); a bias coil (5); a pulse power supply (6) for the bias coil; a magnetic flux conservation section (7); and a control section (8). The bias coil (5) is disposed inside the internal electrode and generates a bias magnetic field between the external and internal electrodes. The pulse power supply (6) for the bias coil pulse-drives the bias coil. The magnetic flux conservation section (7) is disposed outside the external electrode. The control section controls the pulse power supply for the bias coil so as to pulse-drive the bias coil for a time sufficient to apply a bias magnetic field necessary to generate the spheromak plasma between the external and internal electrodes and within a time shorter than a skin time of the magnetic flux of the bias magnetic field into the magnetic flux conservation section.

    摘要翻译： 提供了一种磁化同轴等离子体产生装置，其具有增加的磁化效率并且能够改善功率节省并降低线圈上的热负荷。 产生Spheromak等离子体的磁化同轴等离子体产生装置包括：外部电极（1）; 内部电极（2）; 等离子体产生气体供给部（3）; 电源电路（4）; 偏置线圈（5）; 用于偏置线圈的脉冲电源（6）; 磁通保护部（7）; 和控制部（8）。 偏置线圈（5）设置在内部电极内部，并且在外部和内部电极之间产生偏置磁场。 用于偏置线圈的脉冲电源（6）对偏置线圈进行脉冲驱动。 磁通保护部（7）配置在外部电极的外侧。 控制部分控制用于偏置线圈的脉冲电源，以便将偏置线圈脉冲驱动一段足以施加在外部和内部电极之间产生脉冲等离子体所需的偏置磁场的时间，并且在短于 偏磁场的磁通量的皮肤时间进入磁通保护部。