-
公开(公告)号：US20220386591A1
公开(公告)日：2022-12-08
申请号：US17805100
申请日：2022-06-02
申请人： THE SECANT GROUP LLC
摘要： A cryopreservation process includes combining a cryopreservation composition with a biological sample. The cryopreservation composition includes at least one glycerol ester component. The cryopreservation process also includes then cooling the cryopreservation composition with the biological sample to a cryopreservation temperature. The cryopreservation composition aids in cryopreserving the biological sample at the cryopreservation temperature. A cryopreservation composition includes at least one glycerol ester component. A cryopreserved system includes a biological sample in a cryopreservation composition at a cryopreservation temperature. The cryopreservation composition includes at least one glycerol ester component.
-
公开(公告)号：US20220112634A1
公开(公告)日：2022-04-14
申请号：US17496170
申请日：2021-10-07
发明人： Amanda K. WEBER , Andrew METZGER
IPC分类号： D03D15/567 , D03D27/06 , D04B21/16 , D04B1/20
摘要： A heat-activated crimping textile is disclosed including a plurality of a first yarn, a plurality of a second yarn interlaced with the plurality of the first yarn, and a plurality of a third yarn interlaced with the plurality of the first yarn, the plurality of the second yarn, or both. The third yarn includes a heat-activated shrinkage factor of greater than 30% when exposed to a predetermined temperature. When the heat-activated crimping textile is exposed to an elevated temperature of at least the predetermined temperature, a plurality of crimps propagates along the heat-activated crimping textile, forming a crimped textile.
-
3.发明授权公开(公告)号：US11186926B2
公开(公告)日：2021-11-30
申请号：US16178140
申请日：2018-11-01
摘要： A manufacturing process includes spinning at least one continuous poly(glycerol sebacate) (PGS)/alginate fiber from a polymeric solution comprising PGS and alginate in water, drafting the at least one continuous PGS/alginate fiber in at least one coagulation bath, and drawing the at least one continuous PGS/alginate fiber from the at least one coagulation bath. A yarn includes at least one continuous PGS fiber. A continuous poly(glycerol sebacate) (PGS)/alginate fiber forming system includes a feeding tank holding a polymeric solution of alginate and PGS, a pump, a spinneret, a first coagulation bath, a first winder, a second coagulation bath, a second winder, and a bobbin winder, the system forming at least one continuous PGS/alginate fiber from the polymeric solution of alginate and PGS.
-
公开(公告)号：US20210317278A1
公开(公告)日：2021-10-14
申请号：US17226718
申请日：2021-04-09
摘要： In some embodiments, a polymer film includes a base composition of poly(ethylene-vinyl acetate) and a surface composition comprising hydroxy groups. In some embodiments, a polymer film includes a base layer of a first composition of poly(ethylene-vinyl acetate), a surface layer at a surface of the base layer, and a coating layer of a second composition of a copolymer of glycerol and sebacic acid. The surface layer includes surface hydroxy groups converted from acetate groups of the poly(ethylene-vinyl acetate). The second composition is attached to the surface layer by ester bonds between carboxyl groups of the copolymer and the hydroxy groups. A single-use bioreactor bag includes a polymer film including a base composition of poly(ethylene-vinyl acetate) and a surface composition comprising hydroxy groups. A method of modifying a poly(ethylene-vinyl acetate) film includes converting acetate groups at a first surface of the poly(ethylene-vinyl acetate) film to hydroxy groups.
-
公开(公告)号：US20210024686A1
公开(公告)日：2021-01-28
申请号：US17065971
申请日：2020-10-08
IPC分类号： C08G63/12 , A61K47/55 , C08G63/81 , C08G63/133 , C08G63/123 , C08G63/06 , C08G63/78
摘要： A method includes combining an alcohol-pharmaceutical conjugate, a polyol, and an aqueous liquid in a vessel. The alcohol-pharmaceutical conjugate includes a pharmaceutical compound having at least one carboxyl group attached to the polyol by an ester bond. The method also includes adding an acid monomer to the vessel and heating and removing water from the vessel to produce the polymeric material. The polymeric material includes a polyester copolymer of the acid monomer and the polyol and the pharmaceutical compound.
-
公开(公告)号：US20200179513A1
公开(公告)日：2020-06-11
申请号：US16780177
申请日：2020-02-03
发明人： Peter D. GABRIELE , Jared ELY , Jeremy J. HARRIS
摘要： A method of cancer hyperthermia therapy includes placing a device including an exogenously-excitable polymeric material at a cancer hyperthermia therapy site of a patient. The method also includes supplying an exogenous energy to the device such that the exogenous energy excites the exogenously-excitable polymeric material at the cancer hyperthermia therapy site to heat the cancer hyperthermia therapy site to a hyperthermia temperature. A method of preparing a polymeric material includes combining an alcohol monomer, a seed of the polymeric material, and an aqueous liquid in a vessel. The method also includes adding an acid monomer to the vessel and supplying an exogenous energy to the vessel. The polymeric material is exogenously excited by the exogenous energy to heat the polymeric material. The method further includes removing water from the vessel and producing the polymeric material, which is a polyester, in the vessel.
-
公开(公告)号：US20200157493A1
公开(公告)日：2020-05-21
申请号：US16691040
申请日：2019-11-21
摘要： A engineered textile construction includes a first textile having a first average pore size forming a textile cell growth matrix in which the first textile is a woven or a knit construction, the textile cell growth matrix is configured to have a surface area sufficient to promote cell expansion and the first average pore size is preselected to prevent filling of the pores during cell expansion.
-
8.发明申请公开(公告)号：US20200061240A1
公开(公告)日：2020-02-27
申请号：US16547175
申请日：2019-08-21
发明人： Stephanie REED , Carissa SMOOT , Dennis SHULL , Todd CRUMBLING , John D'OTTAVIO , Peter D. GABRIELE , Jeremy J. HARRIS , Charles Brendan NICHOLSON , Jared ELY
IPC分类号： A61L27/18 , A61L27/54 , A61K31/522 , B33Y80/00 , B29C67/24
摘要： A process forms an implantable product including poly(glycerol sebacate) urethane (PGSU) loaded with an active pharmaceutical ingredient (API). The process includes homogeneously mixing a flowable poly(glycerol sebacate) (PGS) resin with the API and a catalyst to form a resin blend. The process also includes homogeneously combining the resin blend with an isocyanate to form a reaction mixture and injecting the reaction mixture to form the PGSU loaded with the API. An implantable product includes a PGSU loaded with an API. In some embodiments, the implantable product includes at least 40% w/w of the API, and the implantable product releases the API by surface degradation of the PGSU at a predetermined release rate for at least three months under physiological conditions. In some embodiments, the PGSU is formed from a PGS reacted with an isocyanate at an isocyanate-to-hydroxyl stoichiometric (crosslinking) ratio in the range of 1:0.25 to 1:1.25.
-
公开(公告)号：US10526863B2
公开(公告)日：2020-01-07
申请号：US15995777
申请日：2018-06-01
发明人： Peter D. Gabriele , Dennis Shull , Fred B. Pippert
IPC分类号： E21B33/12 , E21B33/134 , E21B43/22 , C08L67/00
摘要： Compositions and methods are beneficial for use in downhole applications, especially oil and gas well bores. A composition includes an elastomer doped with a dopant. The presence of the dopant increases a rate of microbial degradation of the elastomer by a microbe. A method includes forming an article including a doped polymer. The doped polymer includes an elastomer doped with a dopant. The method also includes placing the article in a service environment. The presence of the dopant in the doped polymer increases a rate of microbial degradation of the elastomer by a microbe in the service environment.
-
10.发明申请公开(公告)号：US20190231512A1
公开(公告)日：2019-08-01
申请号：US16264216
申请日：2019-01-31
发明人： Amanda WEBER , Mevlut TASCAN , Carissa SMOOT , Andrew METZGER
IPC分类号： A61F2/07 , D04B1/16 , D03D1/00 , D04B21/00 , D03D13/00 , D03D15/00 , D06M15/507 , D06M15/564
CPC分类号： A61F2/07 , A61F2002/072 , A61F2002/077 , A61F2002/8486 , A61F2210/0076 , A61L31/048 , A61L31/10 , A61L31/129 , A61L31/14 , A61L31/146 , A61L31/148 , D03D1/00 , D03D13/004 , D03D15/00 , D03D2700/0174 , D04B1/16 , D04B21/00 , D06M15/507 , D06M15/564 , D06M2101/32 , D10B2509/06 , D10B2509/08 , C08L67/04 , C08L75/04 , C08L67/02
摘要： Textiles for endovascular and other medical applications having a low-profile are provided. The textiles are woven, knit or braided and are formed of yarns having low (
-
-
-
-
-
-
-
-
-
搜索结果
78 条记录 (耗时 0.018 秒)
