公开(公告)号：US09017969B2

公开(公告)日：2015-04-28

申请号：US13409558

申请日：2012-03-01

申请人： Hiroko Abe ,  Kazuya Tomimoto ,  Yasuko Fujita ,  Tomoko Iwaki ,  Yasunori Chiba ,  Yoshihiro Nakajima ,  Kenichi Nakayama ,  Masatoshi Kataoka ,  Shouki Yatsushiro ,  Shohei Yamamura

发明人： Hiroko Abe ,  Kazuya Tomimoto ,  Yasuko Fujita ,  Tomoko Iwaki ,  Yasunori Chiba ,  Yoshihiro Nakajima ,  Kenichi Nakayama ,  Masatoshi Kataoka ,  Shouki Yatsushiro ,  Shohei Yamamura

IPC分类号： C12P21/00 ,  C12N1/19 ,  C12N1/16 ,  C12N9/10 ,  C12N9/34 ,  C12N9/60 ,  C07K14/47 ,  C12N9/24 ,  C12N15/09

CPC分类号： C12P21/005 ,  C07K14/4726 ,  C07K2319/03 ,  C12N1/16 ,  C12N9/1051 ,  C12N9/24 ,  C12N9/2428 ,  C12N9/2488 ,  C12N9/60 ,  C12N15/09 ,  C12Y204/01109 ,  C12Y204/01132 ,  C12Y204/01255 ,  C12Y302/01003 ,  C12Y302/01113 ,  C12Y304/21048 ,  C12Y304/23025

摘要： The present invention provides: genetically modified yeasts such as mutant yeasts having an ability to produce N-linked sugar chains of Man5GlcNAc2 and a decreased ability to produce O-linked sugar chains, mutant yeasts having an ability to produce N-linked sugar chains of Man5GlcNAc2 and further having an ability to produce N-linked sugar chains of GlcNAc1Man5GlcNAc2, and mutant yeasts having an increased ability to produce and secrete proteins and an ability to produce N-linked sugar chains of Man5GlcNAc2; and a method for producing glycoproteins using them.

摘要翻译： 本发明提供：遗传修饰的酵母，例如具有产生Man5GlcNAc2的N-连接糖链的能力的突变型酵母和产生O-连接的糖链的能力降低的突变体酵母，具有产生Man5GlcNAc2的N-连接糖链的能力的突变体酵母 并且还具有产生GlcNAc1Man5GlcNAc2的N-连接的糖链的能力，以及具有增强的产生和分泌蛋白质的能力和产生Man5GlcNAc2的N-连接的糖链的能力的突变体酵母; 以及使用它们生产糖蛋白的方法。

公开(公告)号：US20130171692A1

公开(公告)日：2013-07-04

申请号：US13409558

申请日：2012-03-01

申请人： Hiroke Abe ,  Kazuya Tomimoto ,  Yasuko Fujita ,  Tomoko Iwaki ,  Yasunori Chiba ,  Yoshihiro Nakajima ,  Kenichi Nakayama ,  Masatoshi Kataoka ,  Shouki Yatsushiro ,  Shohei Yamamura

发明人： Hiroke Abe ,  Kazuya Tomimoto ,  Yasuko Fujita ,  Tomoko Iwaki ,  Yasunori Chiba ,  Yoshihiro Nakajima ,  Kenichi Nakayama ,  Masatoshi Kataoka ,  Shouki Yatsushiro ,  Shohei Yamamura

IPC分类号： C12N1/19 ,  C12P21/00

CPC分类号： C12P21/005 ,  C07K14/4726 ,  C07K2319/03 ,  C12N1/16 ,  C12N9/1051 ,  C12N9/24 ,  C12N9/2428 ,  C12N9/2488 ,  C12N9/60 ,  C12N15/09 ,  C12Y204/01109 ,  C12Y204/01132 ,  C12Y204/01255 ,  C12Y302/01003 ,  C12Y302/01113 ,  C12Y304/21048 ,  C12Y304/23025

摘要： The present invention provides: genetically modified yeasts such as mutant yeasts having an ability to produce N-linked sugar chains of Man5GlcNAc2 and a decreased ability to produce O-linked sugar chains, mutant yeasts having an ability to produce N-linked sugar chains of Man5GlcNAc2 and further having an ability to produce N-linked sugar chains of GlcNAc1Man5GlcNAc2, and mutant yeasts having an increased ability to produce and secrete proteins and an ability to produce N-linked sugar chains of Man5GlcNAc2; and a method for producing glycoproteins using them.

摘要翻译： 本发明提供：遗传修饰的酵母，例如具有产生Man5GlcNAc2的N-连接糖链的能力的突变型酵母和产生O-连接的糖链的能力降低的突变体酵母，具有产生Man5GlcNAc2的N-连接糖链的能力的突变体酵母 并且还具有产生GlcNAc1Man5GlcNAc2的N-连接的糖链的能力，以及具有增强的产生和分泌蛋白质的能力和产生Man5GlcNAc2的N-连接的糖链的能力的突变体酵母; 以及使用它们生产糖蛋白的方法。

公开(公告)号：US20090212660A1

公开(公告)日：2009-08-27

申请号：US11912137

申请日：2006-04-20

申请人： Masaya Iwaki ,  Tomoko Iwaki ,  Koji Akashi ,  Norimichi Anazawa ,  Ken-ichi Kobayashi

发明人： Masaya Iwaki ,  Tomoko Iwaki ,  Koji Akashi ,  Norimichi Anazawa ,  Ken-ichi Kobayashi

IPC分类号： H02N2/00 ,  H01L41/22

CPC分类号： H02N2/007 ,  Y10T29/42

摘要： [Purpose] The present invention relates to an ultrasonic motor having a stator which includes a piezoelectric element for moving a rotor in a prescribed direction by applying a predetermined ultrasonic voltage thereto, and the rotor which is fixed to the stator by a frictional force, and a method for manufacturing an ultrasonic motor, and it has for its purpose to attain decrease of dust appearance by enhancement of a wear resistance, a different hardness, or the like in such a way that a contact part of at least either of a stator and a rotor which constitute the ultrasonic motor is irradiated with ions.[Constitution] An ultrasonic motor characterized in that either or both of contact parts of a stator and a rotor is/are irradiated with ions, thereby to enhance a wear resistance of the contact part or parts.

摘要翻译： 超声波电动机技术领域本发明涉及具有定子的超声波电动机，该定子包括：通过施加规定的超声波电压使规定的方向上的转子向规定的方向移动的压电元件和通过摩擦力固定在定子上的转子， 一种超声波马达的制造方法，其目的是通过提高耐磨性，不同的硬度等来降低灰尘外观，使得定子和 用离子照射构成超声波马达的转子。 [结构]一种超声波马达，其特征在于，定子和转子的接触部中的任一个或两者被离子照射，从而提高接触部件的耐磨性。