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公开(公告)号：US06329548B1
公开(公告)日：2001-12-11
申请号：US09518094
申请日：2000-03-03
申请人： Kazuhiro Hasegawa , Toshiya Tanabe , Keita Minami
发明人： Kazuhiro Hasegawa , Toshiya Tanabe , Keita Minami
IPC分类号： C07C22900
CPC分类号： C07C229/26 , A23K20/142
摘要： Herein is disclosed an aqueous stable lysine solution containing an acid radical in such amount that the solubility of lysine therein has been increased than in the corresponding aqueous lysine base solution, whereby during storage of lysine in the form of a free-lysine solution (liquid composition), the precipitation of lysine base crystals due to the drop in temperature is prevented thereby improving the handling thereof during transportation (transfer) etc.
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公开(公告)号：US07553367B2
公开(公告)日：2009-06-30
申请号：US11423969
申请日：2006-06-14
申请人： Takeshi Kushiku , Dave Steckelberg , Toshiya Tanabe , Jirou Haga , Shinya Fujiki , Kisho Suzuki
发明人： Takeshi Kushiku , Dave Steckelberg , Toshiya Tanabe , Jirou Haga , Shinya Fujiki , Kisho Suzuki
IPC分类号： C30B7/08
CPC分类号： C07C229/26 , C07C227/42
摘要： A diL-lysine monosulfate trihydrate crystal which has a large tabular form and is more easily separable from the mother liquor is described. The crystal is obtained by a novel process wherein crystallization is conducted at a lower temperature.
摘要翻译： 描述了具有大片状并且更容易与母液分离的二L-赖氨酸单硫酸盐三水合物晶体。 通过其中在较低温度下进行结晶的新方法获得晶体。
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公开(公告)号：US20060281945A1
公开(公告)日：2006-12-14
申请号：US11423969
申请日：2006-06-14
申请人： Takeshi Kushiku , Dave Steckelberg , Toshiya Tanabe , Jirou Haga , Shinya Fujiki , Kisho Suzuki
发明人： Takeshi Kushiku , Dave Steckelberg , Toshiya Tanabe , Jirou Haga , Shinya Fujiki , Kisho Suzuki
IPC分类号： C07C227/38
CPC分类号： C07C229/26 , C07C227/42
摘要： A diL-lysine monosulfate trihydrate crystal which has a large tabular form and is more easily separable from the mother liquor is described. The crystal is obtained by a novel process wherein crystallization is conducted at a lower temperature.
摘要翻译： 描述了具有大片状并且更容易与母液分离的二L-赖氨酸单硫酸盐三水合物晶体。 通过其中在较低温度下进行结晶的新方法获得晶体。
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4.发明授权Method for separation of electrolytes, and method for ion exchange of electrolytes with counter-ions 失效电解质分离方法，以及用离子交换电解质的方法
公开(公告)号：US5015386A
公开(公告)日：1991-05-14
申请号：US220597
申请日：1988-07-18
IPC分类号： B01D61/02 , C07C227/40 , C07C229/26
CPC分类号： B01D61/025 , C07C227/40 , C07C229/26
摘要： A method for separating electrolytes which have different charges of the same sign or of carrying out ion exchange of electrolytes with counterions, which comprises causing the electrolytes (anion or cation) to pass through a positively or negatively charged loose reverse-osmotic membrane, in an aqueous solution.
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公开(公告)号：US07161029B2
公开(公告)日：2007-01-09
申请号：US10736511
申请日：2003-12-17
申请人： Takeshi Kushiku , Dave Steckelberg , Toshiya Tanabe , Jirou Haga
发明人： Takeshi Kushiku , Dave Steckelberg , Toshiya Tanabe , Jirou Haga
IPC分类号： C30B29/54
CPC分类号： C07C229/26 , C07C227/42
摘要： A diL-lysine monosulfate trihydrate crystal which has a large tabular form and is more easily separable from the mother liquor. The crystal is obtained by a novel process of conducting crystallization at a lower temperature.
摘要翻译： 具有大片状形式并且更容易与母液分离的二L-赖氨酸单硫酸盐三水合物晶体。 通过在较低温度下进行结晶的新方法获得晶体。
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公开(公告)号：US5814513A
公开(公告)日：1998-09-29
申请号：US732116
申请日：1996-10-15
申请人： Toshiya Tanabe , Tohru Nakamura
发明人： Toshiya Tanabe , Tohru Nakamura
IPC分类号： C12N1/02
CPC分类号： C12N1/02
摘要： A method for removing cells from a fermentation broth obtained by culturing a microorganism belonging to the genus Escherichia through a membrane to separate the cells, comprising adding polyethyleneimine to the fermentation broth to form a mixture, and then filtering the mixture through the membrane to separate the cells, said method resulting in improving the membrane permeation rate compared to when no polyethyleneimine is added.
摘要翻译： 一种从通过膜培养属于埃希氏杆菌属微生物的发酵液中除去细胞以分离细胞的方法，包括向发酵液中加入聚乙烯亚胺以形成混合物，然后通过膜过滤混合物以分离 所述方法与不加入聚乙烯亚胺时相比提高了膜渗透速率。
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公开(公告)号：USRE35609E
公开(公告)日：1997-09-16
申请号：US385888
申请日：1995-02-09
申请人： Masaru Otani , Toshiya Tanabe
发明人： Masaru Otani , Toshiya Tanabe
IPC分类号： C12P19/02 , C12P19/38 , C07H19/06 , B01D15/08 , C07H17/00 , C07H19/00 , C07H19/16 , C07H19/20
CPC分类号： C12P19/02 , C12P19/38 , Y10S435/822
摘要： A biological process for producing a 2',3'-dideoxynucleoside from 2',3'-dideoxyuridine is disclosed. The 2',3'-dideoxynucleoside can be purified readily using a porous nonpolar resin absorbent.
摘要翻译： 公开了从2'，3'-二脱氧尿苷生产2'，3'-二脱氧核苷的生物学方法。 2'，3'-二脱氧核苷可以使用多孔非极性树脂吸收剂容易地纯化。
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公开(公告)号：US20050132947A1
公开(公告)日：2005-06-23
申请号：US10736511
申请日：2003-12-17
申请人： Takeshi Kushiku , Dave Steckelberg , Toshiya Tanabe , Jirou Haga
发明人： Takeshi Kushiku , Dave Steckelberg , Toshiya Tanabe , Jirou Haga
IPC分类号： C07C227/42 , C07C229/26 , C30B1/00
CPC分类号： C07C229/26 , C07C227/42
摘要： A diL-lysine monosulfate trihydrate crystal which has a large tabular form and is more easily separable from the mother liquor. The crystal is obtained by a novel process of conducting crystallization at a lower temperature.
摘要翻译： 具有大片状形式并且更容易与母液分离的二L-赖氨酸单硫酸盐三水合物晶体。 通过在较低温度下进行结晶的新方法获得晶体。
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公开(公告)号：US5194625A
公开(公告)日：1993-03-16
申请号：US450089
申请日：1989-12-13
IPC分类号： A61K31/195 , A61K31/415 , A61P1/16 , A61P13/02 , A61P15/00 , C07C59/185 , C07C59/19 , C07C59/84 , C07C69/66 , C07C227/42 , C07C229/00 , C07C229/26 , C07D233/54 , C07D233/64
CPC分类号： C07D233/64 , C07C229/26 , C07C59/185 , C07C59/19 , C07C59/84
摘要： A compound of the formula:AN/xSwherein A represents an amino acid, N represents an .alpha.-keto acid, S represents a lower alcohol or acetone; and x ranges from 0.1 to 3.
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10.发明授权Process for producing and purifying 2',3'-dideoxynucleosides, and process for producing 2',3'-dideoxy-2',3'-didehydronucleosides 失效2'，3'-二脱氧核苷的生产和纯化方法，以及产生2'，3'-二脱氧-2'，3'-二脱氢核苷的方法
公开(公告)号：US4835104A
公开(公告)日：1989-05-30
申请号：US191370
申请日：1988-05-09
申请人： Kenzo Yokozeki , Hideyuki Shirae , Hiroshi Shiragami , Yasuo Irie , Naohiko Yasuda , Masaru Otani , Toshiya Tanabe
发明人： Kenzo Yokozeki , Hideyuki Shirae , Hiroshi Shiragami , Yasuo Irie , Naohiko Yasuda , Masaru Otani , Toshiya Tanabe
CPC分类号： C12P19/02 , C12P19/38 , Y10S435/822
摘要： A biological process for producing a 2',3'-dideoxyncleoside from 2',3'-dideoxyuridine is disclosed. The 2',3'-dideoxynucleoside can be purified readily using a porous nonpolar resin adsorbent.
摘要翻译： 公开了一种从2'，3'-二脱氧尿苷生产2'，3'-二脱氧核苷的生物工艺。 可以使用多孔非极性树脂吸附剂容易地纯化2'，3'-二脱氧核苷。
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