Method of removing cells from fermentation broth through membrane
    1.
    发明授权
    Method of removing cells from fermentation broth through membrane 失效
    通过膜从发酵液中除去细胞的方法

    公开(公告)号:US5814513A

    公开(公告)日:1998-09-29

    申请号:US732116

    申请日:1996-10-15

    IPC分类号: C12N1/02

    CPC分类号: C12N1/02

    摘要: A method for removing cells from a fermentation broth obtained by culturing a microorganism belonging to the genus Escherichia through a membrane to separate the cells, comprising adding polyethyleneimine to the fermentation broth to form a mixture, and then filtering the mixture through the membrane to separate the cells, said method resulting in improving the membrane permeation rate compared to when no polyethyleneimine is added.

    摘要翻译: 一种从通过膜培养属于埃希氏杆菌属微生物的发酵液中除去细胞以分离细胞的方法,包括向发酵液中加入聚乙烯亚胺以形成混合物,然后通过膜过滤混合物以分离 所述方法与不加入聚乙烯亚胺时相比提高了膜渗透速率。

    Aqueous stable lysine solution
    2.
    发明授权

    公开(公告)号:US06329548B1

    公开(公告)日:2001-12-11

    申请号:US09518094

    申请日:2000-03-03

    IPC分类号: C07C22900

    CPC分类号: C07C229/26 A23K20/142

    摘要: Herein is disclosed an aqueous stable lysine solution containing an acid radical in such amount that the solubility of lysine therein has been increased than in the corresponding aqueous lysine base solution, whereby during storage of lysine in the form of a free-lysine solution (liquid composition), the precipitation of lysine base crystals due to the drop in temperature is prevented thereby improving the handling thereof during transportation (transfer) etc.

    Method for producing basic amino acid solution
    3.
    发明授权
    Method for producing basic amino acid solution 失效
    生产碱性氨基酸溶液的方法

    公开(公告)号:US06800185B2

    公开(公告)日:2004-10-05

    申请号:US10097752

    申请日:2002-03-15

    IPC分类号: B01D6144

    摘要: Herein are disclosed a method for producing a basic amino acid solution which comprises subjecting a solution of a basic amino acid salt to electrodialysis with the use of an electrodialyser equipped with cation exchange membranes and anion exchange membranes in combination, wherein an alkali aqueous solution is added to the solution of a basic amino acid salt during the electrodialysis, whereby not only desalting is caused but also the counter anions of the basic amino acid are removed to such degree that the said counter anions remain in an amount of 40 mol % or smaller based on the basic amino acid, as well as a method for producing a basic amino acid solution which comprises subjecting a solution of a basic amino acid salt to electrodialysis with the use of an electrodialyser equipped with anion exchange membrane alone, wherein an alkali aqueous solution is added to the solution of a basic amino acid salt to adjust the pH of the solution to 7 to 10 during the electrodialysis, whereby the counter anions are removed. According to these methods, a basic amino acid solution having a high concentration within the concentration range in which crystals of a basic amino acid salt are not deposited, can be easily provided, by removing the counter anions from a solution of a basic amino acid salt efficiently by use of electrodialysis.

    摘要翻译: 本发明公开了碱性氨基酸溶液的制造方法,其特征在于,使用配有阳离子交换膜和阴离子交换膜的电渗析器对碱性氨基酸盐的溶液进行电渗析,其中添加碱水溶液 在电渗析中与碱性氨基酸盐的溶液接触,由此不仅可以除去脱盐,而且去除碱性氨基酸的反阴离子,使得所述抗衡阴离子的残留量为40摩尔%以下 碱性氨基酸的制造方法以及碱性氨基酸溶液的制造方法,其特征在于,使用仅含有阴离子交换膜的电渗析器对碱性氨基酸盐的溶液进行电渗析,其中碱性水溶液为 加入到碱性氨基酸盐的溶液中,以在电渗析期间将溶液的pH调节至7至10,其中 通过这些方法,可以容易地提供在碱性氨基酸盐的晶体不沉积的浓度范围内具有高浓度的碱性氨基酸溶液,通过从 通过电渗析有效地溶解碱性氨基酸盐。