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    Ultrafiltration method
    2.
    发明授权
    Ultrafiltration method 失效
    超滤方法

    公开(公告)号：US4523999A

    公开(公告)日：1985-06-18

    申请号：US561974

    申请日：1983-12-16

    申请人： Seiji Toyoshi ,  Tetsuo Tanegawa ,  Masaru Saeki ,  Tetsuya Kawakita

    发明人： Seiji Toyoshi ,  Tetsuo Tanegawa ,  Masaru Saeki ,  Tetsuya Kawakita

    IPC分类号： B01D61/14 ,  B01D61/16 ,  C12P1/00 ,  C12P13/04 ,  B01D13/00

    CPC分类号： B01D61/145 ,  B01D61/18 ,  B01D63/02 ,  B01D63/06 ,  B01D63/087 ,  B01D63/10 ,  C12P1/00 ,  C12P13/04

    摘要： A method for removing impurities including humic substances, gums, polysaccharides, proteins or a mixture thereof from an amino acid fermented liquor obtained from cane, beet molasses, or a mixture thereof, said amino acid being selected from the group consisting of glutamic acid, lysine, and a mixture thereof; said method comprising:(a) adjusting the pH of the fermented liquor to a value of from 2-5 to precipitate said impurities, said impurities having an isoelectric point falling within a pH range of 2-5;(b) ultrafiltering said impurities from said fermented liquor using a semipermeable ultrafiltration membrane.

    摘要翻译： 从由甘蔗，甜菜糖蜜或其混合物获得的氨基酸发酵液中除去包括腐殖质，树胶，多糖，蛋白质或其混合物的杂质的方法，所述氨基酸选自谷氨酸，赖氨酸 ，及其混合物; 所述方法包括：（a）将发酵液的pH调节至2-5的值以沉淀所述杂质，所述杂质的等电点落在2-5的pH范围内; （b）使用半透膜超滤膜从所述发酵液中过滤所述杂质。

    THERAPEUTIC OR PROPHYLACTIC AGENT FOR CORNEAL EPITHELIUM DISORDERS AND/OR CONJUNCTIVAL EPITHELIUM DISORDERS
    5.
    发明申请
    THERAPEUTIC OR PROPHYLACTIC AGENT FOR CORNEAL EPITHELIUM DISORDERS AND/OR CONJUNCTIVAL EPITHELIUM DISORDERS 审中-公开
    角膜上皮病和/或连续上皮疾病的治疗剂或预防剂

    公开(公告)号：US20130245119A1

    公开(公告)日：2013-09-19

    申请号：US13885826

    申请日：2011-11-18

    申请人： Akiko Harauma ,  Fuminori Kawabata ,  Toru Moriguchi ,  Tetsuya Kawakita ,  Kazuo Tsubota

    发明人： Akiko Harauma ,  Fuminori Kawabata ,  Toru Moriguchi ,  Tetsuya Kawakita ,  Kazuo Tsubota

    IPC分类号： A61K31/202

    CPC分类号： A61K31/202 ,  A61K9/0053 ,  A61K31/20 ,  A61K31/232 ,  A61K31/661 ,  A61K35/60 ,  A61K35/612

    摘要： The present invention provides an effective and safe prophylactic and therapeutic pharmaceutical agent and supplement for corneal epithelium disorders and/or conjunctival epithelial disorders. This is a therapeutic and/or prophylactic agent for corneal epithelium disorders and/or conjunctival epithelial disorders comprising eicosapentaenoic acid and/or docosahexaenoic acid, a glycerin ester or phospholipid comprising these fatty acids as constituent fatty acids, or a lower alcohol ester of these fatty acids as active ingredients. These preferably comprise EPA and/or DHA in the form of a refined fish oil or refined krill oil. A total of at least approximately 50 to 5,000 mg of EPA and/or DHA or the esters thereof are taken daily, thereby easing corneal epithelium disorders and/or conjunctival epithelial disorders. In addition, the amount of tears may be recovered.

    摘要翻译： 本发明提供了一种有效和安全的预防和治疗药剂以及角膜上皮病和/或结膜上皮疾病的补充剂。 这是包含二十碳五烯酸和/或二十二碳六烯酸的角膜上皮细胞病和/或结膜上皮病症的治疗和/或预防剂，包含这些脂肪酸作为构成脂肪酸的甘油酯或磷脂，或这些脂肪酸的低级醇酯 酸作为活性成分。 这些优选包含精制鱼油或精制磷虾油形式的EPA和/或DHA。 每天服用至少约50至5,000mg的EPA和/或DHA或其酯，从而缓解角膜上皮病和/或结膜上皮病。 此外，眼泪量可以恢复。

    Purification of lysine by reverse-phase osmosis
    6.
    发明授权
    Purification of lysine by reverse-phase osmosis 失效
    通过反相渗透法纯化赖氨酸

    公开(公告)号：US4601829A

    公开(公告)日：1986-07-22

    申请号：US685792

    申请日：1984-12-24

    申请人： Tetsuya Kaneko ,  Masaru Saeki ,  Kiyoshi Tanaka ,  Tetsuya Kawakita

    发明人： Tetsuya Kaneko ,  Masaru Saeki ,  Kiyoshi Tanaka ,  Tetsuya Kawakita

    IPC分类号： C07C227/40 ,  C07C67/00 ,  C07C227/00 ,  C07C227/28 ,  C07C229/26 ,  C12P13/08 ,  B01D13/00

    CPC分类号： C12P13/08 ,  B01D61/025 ,  Y02P20/126

    摘要： A process for purifying lysine in a lysine production process, which involves passing a solution containing lysine over a cation exchange resin such that lysine adsorbs onto the resin, eluting adsorbed lysine from the resin with an aqueous solution of ammonia to produce a lysine-containing elution liquid, passing the elution liquid directly to a reverse osmosis membrane system, and concentrating the lysine-containing elution liquid with the reverse osmosis membrane system such that ammonia is selectively removed from the lysine containing elution; the aqueous ammonia which is separated from the lysine may be recycled through the cation exchange resin to regenerate the resin or to elute more lysine from the resin.

    摘要翻译： 一种在赖氨酸生产过程中纯化赖氨酸的方法，其涉及使含有赖氨酸的溶液通过阳离子交换树脂，使得赖氨酸吸附到树脂上，用氨水溶液洗脱树脂上的赖氨酸，产生含赖氨酸的洗脱液 液体，将洗脱液直接通入反渗透膜系统，并将含赖氨酸的洗脱液与反渗透膜系统浓缩，使氨选择性地从含有赖氨酸的洗脱液中除去; 从赖氨酸分离的氨水可以通过阳离子交换树脂再循环以再生树脂或从树脂洗脱更多的赖氨酸。

    Process for the production of a fermentation starting material
    9.
    发明授权
    Process for the production of a fermentation starting material 失效
    生产发酵原料的方法

    公开(公告)号：US4543330A

    公开(公告)日：1985-09-24

    申请号：US567673

    申请日：1984-01-03

    申请人： Hideyuki Morimoto ,  Masaru Saeki ,  Tetsuya Kawakita

    发明人： Hideyuki Morimoto ,  Masaru Saeki ,  Tetsuya Kawakita

    IPC分类号： C12N1/00 ,  C12P13/14

    CPC分类号： C12P13/14 ,  C12N1/00

    摘要： A process for the production of a fermentation starting material from cane molasses which comprises: inverting most of the sugar contained in cane molasses either enzymatically with invertase or with a mineral acid, passing the cane molasses containing invert sugar through a column containing a cation exchange resin, eluting invert sugar from the resin with water (pH 5-8), and obtaining an eluate fraction containing the invert sugar to be used as a carbon source for the production of L-glutamic acid by a fermentation technique.

    摘要翻译： 一种从甘蔗糖蜜生产发酵起始材料的方法，其包括：用蔗糖酶或无机酸酶反转甘蔗糖蜜中的大部分糖，将含有转化糖的蔗糖糖通过含有阳离子交换树脂的柱 ，用水（pH 5-8）从树脂中转移糖，并通过发酵技术获得含有转化糖的洗脱液级分，用作生产L-谷氨酸的碳源。

    Seasoning composition having crab meat flavor
    10.
    发明授权
    Seasoning composition having crab meat flavor 失效
    具有蟹肉风味的调味料

    公开(公告)号：US4376132A

    公开(公告)日：1983-03-08

    申请号：US309100

    申请日：1981-10-06

    申请人： Hajime Eguchi ,  Hideko Furukawa ,  Tetsuya Kawakita

    发明人： Hajime Eguchi ,  Hideko Furukawa ,  Tetsuya Kawakita

    IPC分类号： A23L27/22 ,  A23L27/23 ,  A23L1/221 ,  A23L1/228 ,  A23L1/229 ,  A23L1/231

    CPC分类号： A23L27/23 ,  A23L27/22

    摘要： A crab meat flavored seasoning composition, comprising:(a) not less than 50% by wt. of amino acids,(b) not less than 2% by wt. of 5'-nucleotides,(c) not less than 30% by wt. of inorganic salts,(d) not less than 1% by wt. of glucides and(e) a substantial amount of crab shell extract or synthetic crab aromatics; said amino acids comprising not less than 40% by wt. of glycine, not less than 40% by wt. of arginine and glutamic acid and not less than 10% by wt. of alanine, said 5'-nucleotides comprising not less than 50% by wt. of GMP and said inorganic salts comprising not less than 20% by wt. of potassium ion, not less than 40% by wt. of phosphate ion and not more than 40% by wt. of sodium and chlorine ions.

    摘要翻译： 一种蟹肉调味调味料组合物，其包含：（a）不低于50重量％ 的氨基酸，（b）不小于2重量％。 的5'-核苷酸，（c）不小于30重量％。 的无机盐，（d）不小于1重量％。 （e）大量的蟹壳提取物或合成的蟹类芳烃; 所述氨基酸不低于40重量％。 的甘氨酸，不小于40重量％。 的精氨酸和谷氨酸，并且不小于10重量％。 的丙氨酸，所述5'-核苷酸不小于50重量％。 的GMP，并且所述无机盐包含不少于20重量％。 的钾离子，不小于40重量％。 的磷酸根离子，不超过40重量％。 的钠和氯离子。