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1.发明申请公开(公告)号：US20250144274A1
公开(公告)日：2025-05-08
申请号：US19015146
申请日：2025-01-09
Inventor： Kalpathy B. Sundaram , Varsha Naga , Shraddha Dhanraj Nehate , Ashwin Kumar Saikumar
Abstract: A novel anti-microbial coating and uses thereof on medical devices are presented. The novel coating is comprised of a layer of boron carbon nitride (BCN) coated onto a medical device such as a catheter. The BCN coating was found to inhibit bacterial growth by at least 80% and reduce biofilm formation by at least 60% on the treated surface of the catheter. This coating can be used to reduce or prevent central line associated bloodstream infections (CLABSI) in patients as well as inhibit bacterial growth and biofilm formation on a variety of medical devices or polymeric surfaces.
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公开(公告)号：US20250141185A1
公开(公告)日：2025-05-01
申请号：US18934858
申请日：2024-11-01
Inventor： Luke Milbocker , Michael Milbocker , Arkadiy Lyakh
Abstract: A quantum cascade laser (QCL) may include multiple branch waveguide regions having one or more laser cores providing optical gain at one or more output wavelengths, a stem waveguide region, and multiple couplers arranged to couple light from the plurality of branch waveguide regions to the stem waveguide region. Each of the couplers may include two or more curved waveguide regions having a continuously-varying radius of curvature providing that a fundamental transverse mode at the output wavelengths is dominant, and a coupler to combine light from the two or more curved waveguides and maintain dominance of the fundamental transverse mode at the output wavelengths. The fundamental transverse mode at the output wavelengths may be dominant in output light from the stem waveguide.
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公开(公告)号：US20250118391A1
公开(公告)日：2025-04-10
申请号：US18836064
申请日：2023-01-10
Applicant: UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC. , THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
Inventor： Jiann-Shiun YUAN , Arash KESHAVARZI ARSHADI , Milad SALEM , Hani GOODARZI
Abstract: A method for training a deep learning model configured for virtual screening of molecules for micro ribonucleic acid (miRNA) drug discovery includes creating a training dataset including a plurality of assay datasets. The method also includes training the deep learning model to learn a plurality of tasks; performing, using the deep learning model, inference for the respective task associated with at least one miRNA assay dataset; and evaluating respective performance metrics associated with the respective predictions for each of the plurality of tasks. The method further includes selecting a set of the plurality of assay datasets for training; and training the deep learning model to learn a set of the plurality of tasks using the set of the plurality of assay datasets. The trained deep learning model is configured to predict molecules capable of affecting a target miRNA.
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公开(公告)号：US20250099609A1
公开(公告)日：2025-03-27
申请号：US18892448
申请日：2024-09-22
Inventor： Melanie Coathup , Sudipta Seal , Fei Wei , Elayaraja Kolanthai
Abstract: Multifunctional cerium oxide-P7C3 (aminopropyl carbazole) chimeric nanocompositions and methods for using these nanocompositions for enhancing bone deposition are provided. For example, these nanocompositions can be used to combat radiation-induced bone tissue/cell damage, to treat any disorders that promote osteoporosis, and/or to treat bone trauma/injury.
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公开(公告)号：US20250091452A1
公开(公告)日：2025-03-20
申请号：US18776924
申请日：2024-07-18
Inventor： Jayan Thomas , Deepak Pandey , Rajkumar Gurjar , Maydenee Maydur Tresa
IPC: B60L50/64 , B60L50/40 , B62D29/04 , H01G11/04 , H01G11/10 , H01G11/26 , H01G11/52 , H01G11/62 , H01M10/0565 , H01M10/058 , H01M50/437 , H01M50/44 , H01M50/457
Abstract: A glass fiber-based structural composite offers an alternative or supplement to carbon fibers in areas such as battery storage. Through electroless deposition of conductive materials like copper and nickel, the glass fiber surface is made conducting and functions as a good current collector. By using anode and cathode materials like manganese (II, III) oxide and Zinc, cathode and anode mats on the copper- and nickel-coated glass fibers are created via hydrothermal and electro-deposition methods. In one example application, the anode and cathode mats are in an alternate square patterned arrangement using copper and nickel-coated glass fiber as a current collector. The device, with a capacity of >300 mAh/g at 0.1 A/g is assembled using an alternate system of epoxy and electrolyte. Uncoated pristine glass fiber ladened and patterned with electrolyte are used as a separator. Uncoated pristine glass fiber ladened with epoxy can be used as an insulator between two devices.
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Patent Agency Ranking
公开(公告)号：US20250082823A1
公开(公告)日：2025-03-13
申请号：US18886830
申请日：2024-09-16
Applicant: University of Central Florida Research Foundation, Inc. , Sanford Burnham Prebys Medical Discovery Institute
Inventor： Sudipta SEAL , Soumen DAS , William SELF , Dwight TOWLER
IPC: A61L27/30 , A61L27/04 , A61L27/10 , A61L27/14 , A61L27/54 , C25D13/02 , C25D13/12 , C25D13/18 , C25D15/00
Abstract: An implant is provided comprising a substrate having one or more nanoceria coatings coated at least partially thereon, wherein the one or more nanoceria coatings comprise surface cerium having a 3+/4+ oxidation state ratio such that the one or more nanoceria coatings exhibit catalase mimetic activity, superoxide dismutase mimetic activity, or both. Methods are provided for forming a nanoceria coating. The coating has nanoceria having a surface cerium 3+/4+ oxidation state ratio such that such that the coating exhibits catalase mimetic activity, superoxide dismutase mimetic activity, or both. Also disclosed is a method of reducing degradation of an implant by placing nanoceria in proximity to a bone-implant interface.
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公开(公告)号：US12237814B2
公开(公告)日：2025-02-25
申请号：US17545166
申请日：2021-12-08
Inventor： Kenle Chen , Yuchen Cao
Abstract: Described herein are load-modulated balanced amplifiers. An example load-modulated balanced amplifier can include a radio frequency (RF) input port, a RF output port, a peaking amplifier circuit operably coupled between the RF input and RF output ports, where the peaking amplifier circuit is a balanced amplifier that includes a pair of power amplifiers, and a carrier amplifier circuit operably coupled to the RF input port.
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公开(公告)号：US12213896B2
公开(公告)日：2025-02-04
申请号：US17632024
申请日：2020-08-03
Inventor： Hwan Choi , Gabriel Rios Carbonell
Abstract: A method and apparatus for enhancing the operation of leg prothesis is provided. The apparatus includes a cable configured to be attached to the leg prosthesis worn by a subject to move through a plurality of gait phases. The apparatus also includes a module configured to be mounted to the leg prosthesis. The module includes a tension spring configured to engage the cable to maintain tension in the cable. The module also includes a locking mechanism configured to lock a position of the tension spring and maintain a length of the cable defined between the module and the leg prosthesis during a first gait phase of the plurality of gait phases. The locking mechanism is further configured to unlock the position of the tension spring to permit variation of the length of the cable during a second gait phase of the plurality of gait phases.
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公开(公告)号：US20250029410A1
公开(公告)日：2025-01-23
申请号：US18667244
申请日：2024-05-17
Inventor： Yogesh Singh Rawat , Aayush Jung Bahadur Rana
IPC: G06V20/70 , G06V10/774
Abstract: An active sparse labeling system that provides high performance and low annotation costs by performing partial instance annotation (i.e., sparse labeling) by frame level selection to annotate the most informative frames, thereby improving action detection task efficiencies. The active sparse labeling system utilizes a frame level cost estimation to determine the utility of each frame in a video based on the frame's impact on action detection. The system includes an adaptive proximity-aware uncertainty model, which is an uncertainty-based frame scoring mechanism. The adaptive proximity-aware uncertainty model estimates a frame's utility using the uncertainty of detections of the frame's proximity to existing annotations, thereby determining a diverse set of frames in a video which are effective for learning the task of dense video understanding (such as action detection). In addition, the active sparse labeling system includes a loss formulation training model (max-Gaussian weighted loss) that uses weighted pseudo-labeling.
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10.发明申请公开(公告)号：US20250007702A1
公开(公告)日：2025-01-02
申请号：US18597258
申请日：2024-03-06
Inventor： Salem F. Hegazy , Bahaa E. A. Saleh
IPC: H04L9/08
Abstract: A quantum key distribution system may include a transceiver including a state randomizer to impart a random state transformation to one or more qubits of a generated faint pulse and a quantum bit encoder to reflect the faint pulse back to the transceiver with one or more encoded bits. The transceiver may receive a return pulse through the communication channel, where the state randomizer reverses the random state transformation. The transceiver may include a set of two detectors to measure the return pulse at time-gated timeslots associated with possible paths of the return pulse. Reception of the faint pulse from the quantum bit encoder as the return pulse triggers a detector in one or more known time-gated timeslots determined based on the random state transformation, while reception of a faked-state pulse results in a non-zero probability of triggering of a detector in a different time-gated timeslot.
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