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    Fat Accumulation Inhibitor
    2.
    发明申请
    Fat Accumulation Inhibitor 审中-公开
    脂肪蓄积抑制剂

    公开(公告)号：US20090253658A1

    公开(公告)日：2009-10-08

    申请号：US12296222

    申请日：2007-04-06

    申请人： Reo Tanaka ,  Tomoyuki Isogai ,  Yuko Haruta ,  Susumu Miura ,  Ken Kato ,  Toshimitsu Yoshioka ,  Hiroshi Kawakami ,  Satoshi Higurashi ,  Hiroaki Matsuyama

    发明人： Reo Tanaka ,  Tomoyuki Isogai ,  Yuko Haruta ,  Susumu Miura ,  Ken Kato ,  Toshimitsu Yoshioka ,  Hiroshi Kawakami ,  Satoshi Higurashi ,  Hiroaki Matsuyama

    IPC分类号： A61K31/66 ,  C07F9/06

    CPC分类号： A61K35/20 ,  A23L2/52 ,  A23L33/19 ,  A23V2002/00 ,  A61K31/661 ,  A23V2200/332 ,  A23V2250/1844

    摘要： To provide a fat accumulation inhibitor and a food or drink for inhibiting fat accumulation, a visceral fat accumulation inhibitor and a food or drink for inhibiting visceral fat accumulation, or an agent for accelerating increase and/or inhibiting decrease of an adiponectin concentration in blood and a food or drink for accelerating increase and/or inhibiting decrease of an adiponectin concentration in blood.A fat accumulation inhibitor for a fat cell, which comprises a milk-derived phospholipid as an active ingredient, and a food or drink for inhibiting fat accumulation in a fat cell, which comprises a milk-derived phospholipid. A visceral fat accumulation inhibitor comprising a sphingosine-containing phospholipid or a derivative thereof as an active ingredient, and a food or drink for inhibiting visceral fat accumulation. An agent for accelerating increase and/or inhibiting decrease of an adiponectin concentration in blood, which comprises a sphingosine-containing phospholipid or a derivative thereof as an active ingredient, and a food or drink for accelerating increase and/or inhibiting decrease of an adiponectin concentration in blood.

    摘要翻译： 提供一种脂肪蓄积抑制剂和用于抑制脂肪蓄积的食物或饮料，内脏脂肪蓄积抑制剂和用于抑制内脏脂肪蓄积的食品或饮料，或用于加速和/或抑制血液中脂联素浓度降低的试剂，以及 用于促进血液中脂联素浓度增加和/或抑制降低的食物或饮料。 一种脂肪蓄积抑制剂，其包含乳源性磷脂作为活性成分的脂肪蓄积抑制剂，以及包含乳源性磷脂的脂肪细胞中抑制脂肪蓄积的食品或饮料。 含有鞘氨醇的磷脂或其衍生物作为活性成分的内脏脂肪蓄积抑制剂和抑制内脏脂肪蓄积的食品或饮料。 用于促进增加和/或抑制血液中脂联素浓度降低的药物，其包含含鞘氨醇的磷脂或其衍生物作为活性成分，以及用于加速和/或抑制脂联素浓度降低的食品或饮料 在血中

    SENSE-IMPROVING AGENT
    4.
    发明申请
    SENSE-IMPROVING AGENT 审中-公开
    感知改进剂

    公开(公告)号：US20110124606A1

    公开(公告)日：2011-05-26

    申请号：US12743391

    申请日：2008-11-19

    申请人： Tatsuya Watanabe ,  Yuko Haruta ,  Ken Kato ,  Toshimitsu Yoshioka

    发明人： Tatsuya Watanabe ,  Yuko Haruta ,  Ken Kato ,  Toshimitsu Yoshioka

    IPC分类号： A61K31/688 ,  C07F9/10 ,  A61P17/00

    CPC分类号： A61Q19/00 ,  A23K20/158 ,  A23K20/26 ,  A23K50/40 ,  A23L2/52 ,  A23L33/115 ,  A61K8/0212 ,  A61K8/553 ,  A61K8/68 ,  A61K31/688

    摘要： Disclosed are: a sense-improving agent which comprises, as an active ingredient, a phospholipid or a sphingosine-containing phospholipid and/or a derivative thereof, particularly a sphingomyelin, and which has an effect of improving the dulling of senses at a periphery when ingested orally or directly applied to the skin; and a sense-improving food, beverage, feed or cosmetic comprising the sense-improving agent. The phospholipid to be used may be a chemically synthesized phospholipid or a naturally occurring phospholipid, preferably a phospholipid derived from an edible material such as soybean and egg yolk, particularly preferably a phospholipid derived from milk.

    摘要翻译： 公开了一种感觉改善剂，其包含作为活性成分的磷脂或含鞘氨醇的磷脂和/或其衍生物，特别是鞘磷脂，并且具有改善周围感觉钝化的效果， 口服或直接施用于皮肤; 以及包含感官改善剂的感官改善食品，饮料，饲料或化妆品。 所使用的磷脂可以是化学合成的磷脂或天然存在的磷脂，优选来源于可食用物质如大豆和蛋黄的磷脂，特别优选来自牛奶的磷脂。

    Medicine, Food and Drink or Feed Containing Sphingomyelin
    6.
    发明申请
    Medicine, Food and Drink or Feed Containing Sphingomyelin 审中-公开
    医药，饮食或含有鞘磷脂的饲料

    公开(公告)号：US20100048928A1

    公开(公告)日：2010-02-25

    申请号：US11992365

    申请日：2006-09-22

    申请人： Ken Kato ,  Susumu Miura ,  Leo Tanaka ,  Hiroshi Ueno ,  Noriko Ueda ,  Yuko Haruta ,  Toshimitsu Yoshioka

    发明人： Ken Kato ,  Susumu Miura ,  Leo Tanaka ,  Hiroshi Ueno ,  Noriko Ueda ,  Yuko Haruta ,  Toshimitsu Yoshioka

    IPC分类号： C07F9/09

    CPC分类号： A61K31/688 ,  A23K20/158 ,  A23K50/40 ,  A23K50/48 ,  A23L2/52 ,  A23L33/10 ,  A23L33/12 ,  A23V2002/00 ,  A61K8/68 ,  A61Q7/00 ,  A61Q19/02 ,  C07F9/10 ,  A23V2250/21 ,  A23V2200/304 ,  A23V2200/32

    摘要： It is intended to find novel pharmaceutical use of sphingomyelin and to provide preventive or therapeutic agents for various diseases as well as a food and drink product and feed comprising any of these agents. The present invention provides a pharmaceutical agent which contains sphingomyelin as an active ingredient and is any of the following agents: 1) a sialomucin secretion promoter, 2) an agent for preventing drunken sickness (hangover), 3) an antiallergic agent, 4) an antioxidant, 5) an agent for defending against infection, 6) a hair growth agent, 7) a therapeutic agent for demyelinating disease, 8) an anti-pigmentation agent, 9) an anti-inflammatory agent, and 10) an agent for improving learning ability. The present invention also provides a food and drink product or feed, characterized by comprising the agent. It is preferred that the sphingomyelin should be derived from milk.

    摘要翻译： 旨在找到鞘磷脂的新药用途，并提供各种疾病的预防或治疗剂，以及包含任何这些药剂的食品和饮料产品和饲料。 本发明提供含有鞘磷脂作为活性成分的药剂，其为以下药剂：1）唾液酸粘蛋白分泌促进剂，2）防酒醉药（宿醉）3，抗过敏剂4） 抗氧化剂，5）防止感染的药剂，6）毛发生长剂，7）脱髓鞘疾病的治疗剂，8）抗色素沉着剂，9）抗炎剂，和10）改善剂 学习能力 本发明还提供一种食品和饮料产品或饲料，其特征在于包含该试剂。 鞘磷脂优选来源于牛奶。

    Medicine, Food And Drink Or Feed Containing Sphingomyelin
    7.
    发明申请
    Medicine, Food And Drink Or Feed Containing Sphingomyelin 审中-公开
    医药，食品和饮料或含有鞘磷脂的饲料

    公开(公告)号：US20120208783A1

    公开(公告)日：2012-08-16

    申请号：US13347464

    申请日：2012-01-10

    申请人： Ken Kato ,  Susumu Miura ,  Leo Tanaka ,  Hiroshi Ueno ,  Noriko Ueda ,  Yuko Haruta ,  Toshimitsu Yoshioka

    发明人： Ken Kato ,  Susumu Miura ,  Leo Tanaka ,  Hiroshi Ueno ,  Noriko Ueda ,  Yuko Haruta ,  Toshimitsu Yoshioka

    IPC分类号： A61K31/688 ,  A61P25/00 ,  C07F9/09

    CPC分类号： A61K31/688 ,  A23K20/158 ,  A23K50/40 ,  A23K50/48 ,  A23L2/52 ,  A23L33/10 ,  A23L33/12 ,  A23V2002/00 ,  A61K8/68 ,  A61Q7/00 ,  A61Q19/02 ,  C07F9/10 ,  A23V2250/21 ,  A23V2200/304 ,  A23V2200/32

    摘要： It is intended to find novel pharmaceutical use of sphingomyelin and to provide preventive or therapeutic agents for various diseases as well as a food and drink product and feed comprising any of these agents. The present invention provides a pharmaceutical agent which contains sphingomyelin as an active ingredient and is any of the following agents: 1) a sialomucin secretion promoter, 2) an agent for preventing drunken sickness (hangover), 3) an antiallergic agent, 4) an antioxidant, 5) an agent for defending against infection, 6) a hair growth agent, 7) a therapeutic agent for demyelinating disease, 8) an anti-pigmentation agent, 9) an anti-inflammatory agent, and 10) an agent for improving learning ability. The present invention also provides a food and drink product or feed, characterized by comprising the agent. It is preferred that the sphingomyelin should be derived from milk.

    摘要翻译： 旨在找到鞘磷脂的新药用途，并提供各种疾病的预防或治疗剂，以及包含任何这些药剂的食品和饮料产品和饲料。 本发明提供含有鞘磷脂作为活性成分的药剂，其为以下药剂：1）唾液酸粘蛋白分泌促进剂，2）防酒醉药（宿醉）3，抗过敏剂4） 抗氧化剂，5）防止感染的药剂，6）毛发生长剂，7）脱髓鞘疾病的治疗剂，8）抗色素沉着剂，9）抗炎剂，和10）改善剂 学习能力 本发明还提供一种食品和饮料产品或饲料，其特征在于包含该试剂。 鞘磷脂优选来源于牛奶。

    Fat Accumulation Inhibitor and Method of Use Thereof
    8.
    发明申请
    Fat Accumulation Inhibitor and Method of Use Thereof 审中-公开
    脂肪蓄积抑制剂及其使用方法

    公开(公告)号：US20120077780A1

    公开(公告)日：2012-03-29

    申请号：US13240739

    申请日：2011-09-22

    申请人： Reo Tanaka ,  Tomoyuki Isogai ,  Yuko Haruta ,  Susumu Miura ,  Ken Kato ,  Toshimitsu Yoshioka ,  Hiroshi Kawakami ,  Satoshi Higurashi ,  Hiroaki Matsuyama

    发明人： Reo Tanaka ,  Tomoyuki Isogai ,  Yuko Haruta ,  Susumu Miura ,  Ken Kato ,  Toshimitsu Yoshioka ,  Hiroshi Kawakami ,  Satoshi Higurashi ,  Hiroaki Matsuyama

    IPC分类号： A61K31/688 ,  A61K31/685 ,  A61P3/04 ,  A61K31/683

    CPC分类号： A61K35/20 ,  A23L2/52 ,  A23L33/19 ,  A23V2002/00 ,  A61K31/661 ,  A23V2200/332 ,  A23V2250/1844

    摘要： The present disclosure relates to a method of inhibiting a fat accumulation for a fat cell in a subject, which includes administering a fat accumulation inhibitor for a fat cell which includes a milk-derived phospholipid as an active ingredient to the subject. The present disclosure also relates to a method of inhibiting a visceral fat accumulation in a subject, which includes administering the visceral fat accumulation inhibitor which includes a sphingosine-containing phospholipid as an active ingredient to the subject. The present disclosure also relates to a method of accelerating increase and/or inhibiting decrease of an adiponectin concentration in blood, which includes administering an agent which includes a sphingosine-containing phospholipid as an active ingredient to the blood. The present disclosure also relates to a method of inhibiting a fat accumulation for a fat cell in a subject, which includes administering a milk-derived phospholipid to a subject.

    摘要翻译： 本公开涉及抑制受试者中的脂肪细胞的脂肪蓄积的方法，其包括向受试者施用包含作为有效成分的乳源性磷脂的脂肪细胞的脂肪蓄积抑制剂。 本公开还涉及抑制受试者内脏脂肪蓄积的方法，其包括向受试者施用含有鞘氨醇的磷脂作为活性成分的内脏脂肪蓄积抑制剂。 本公开还涉及一种促进血液中脂联素浓度增加和/或抑制降低的方法，其包括向血液中施用含有鞘氨醇的磷脂作为活性成分的药剂。 本公开还涉及抑制受试者中的脂肪细胞的脂肪蓄积的方法，其包括向受试者施用乳源性磷脂。

    Skin Beautifying Agent
    10.
    发明申请
    Skin Beautifying Agent 审中-公开
    皮肤美容剂

    公开(公告)号：US20100197638A1

    公开(公告)日：2010-08-05

    申请号：US12524602

    申请日：2008-01-29

    申请人： Ken Kato ,  Yuko Haruta ,  Tatsuya Watanabe ,  Hiroshi Ueno ,  Noriko Ueda ,  Toshimitsu Yoshioka

    发明人： Ken Kato ,  Yuko Haruta ,  Tatsuya Watanabe ,  Hiroshi Ueno ,  Noriko Ueda ,  Toshimitsu Yoshioka

    IPC分类号： A61K31/661 ,  A61Q19/00

    CPC分类号： A61K31/661 ,  A23K20/158 ,  A23K50/40 ,  A23L33/10 ,  A23L33/12 ,  A23V2002/00 ,  A23V2200/318 ,  A23V2250/18

    摘要： The present invention aims to provide a skin-beautifying agent, food, beverage, or feed for skin-beautification which has cosmetic effects such as moisturizing and beautifying the skin as well as preventing skin roughness and wrinkles by oral intake. The present invention further aims to provide a skin-beautifying agent containing a milk-derived phospholipid as an effective ingredient, and to provide food, beverage, or feed for skin-beautification containing the skin-beautifying agent. The milk-derived phospholipid is preferably a composition prepared from milk or milk material containing 40 to 70% by weight of lipid in a total solid content and containing 30% or more by weight of milk-derived phospholipid.

    摘要翻译： 本发明的目的在于提供一种具有美容效果的美肤用品，食品，饮料或美容用品，其具有美容效果，例如保湿和美化皮肤，以及通过口服摄入来防止皮肤粗糙和皱纹。 本发明的目的还在于提供一种含有来源于乳的磷脂作为有效成分的皮肤美容剂，提供含有皮肤美容剂的皮肤美容用食品，饮料或饲料。 来自乳的磷脂优选为由含有40〜70重量％总固体含量的脂质并含有30重量％以上的来源于磷脂的磷脂的乳或乳制品制成的组合物。