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    DEVICE AND METHOD FOR MAKING ASEPTIC CONNECTIONS
    1.
    发明申请
    DEVICE AND METHOD FOR MAKING ASEPTIC CONNECTIONS 审中-公开

    公开(公告)号：US20200155759A1

    公开(公告)日：2020-05-21

    申请号：US16752075

    申请日：2020-01-24

    Applicant: AMGEN INC.

    Inventor： Ian B. Hanson ,  Lawton Laurence ,  Antonio Ubach ,  Rajan Ramaswamy ,  Daniel S. Codd ,  Scott Beaver ,  Kevin L. Bokelman ,  Danielle Feldman ,  Matthew J. Clemente

    IPC: A61M5/162 ,  A61M5/142 ,  A61M5/14 ,  A61M5/158 ,  A61M5/145 ,  A61J1/20 ,  A61M39/18

    Abstract: The present invention provides devices and methods for establishing aseptic connections between two or more components or subassemblies. The devices may be used in medical devices such as drug delivery pumps (10). In some embodiments, a connection is made between a drug container (50, 1050, 2050) and a fluid pathway connection assembly (300, 1300, 2300). The fluid pathway connection assembly may include a connection hub (312, 1312, 2312), a piercing member (316, 1316, 2316), and a piercing member retainer (314, 1314, 2314). The assembly may further include a first film (318, 1318, 2318) covering a cavity (312A, 1312A, 2312A), thereby maintaining the aseptic condition of the cavity. The drug container may hold a fluid drug and include a pierceable seal (326, 1326, 2326). A second film (322, 1322, 2322) may cover a recess (328, 1328, 2328) formed by the seal and thereby maintain the aseptic condition of the interior of the chamber. The piercing member may be caused to pierce the first and second film and the pierceable seal to open a fluid pathway for delivery of the fluid drug through the fluid pathway connection assembly.

    Device and method for making aseptic connections
    4.
    发明授权
    Device and method for making aseptic connections 有权

    公开(公告)号：US10569014B2

    公开(公告)日：2020-02-25

    申请号：US15552828

    申请日：2016-03-02

    Applicant: AMGEN INC.

    Inventor： Ian B. Hanson ,  Lawton Laurence ,  Antonio Ubach ,  Rajan Ramaswamy ,  Daniel S. Codd ,  Scott Beaver ,  Kevin L. Bokelman ,  Danielle Feldman ,  Matthew J. Clemente

    IPC: A61M5/162 ,  A61M5/158 ,  A61M5/14 ,  A61M5/142

    Abstract: The present invention provides devices and methods for establishing aseptic connections between two or more components or subassemblies. The devices may be used in medical devices such as drug delivery pumps (10). In some embodiments, a connection is made between a drug container (50, 1050, 2050) and a fluid pathway connection assembly (300, 1300, 2300). The fluid pathway connection assembly may include a connection hub (312, 1312, 2312), a piercing member (316, 1316, 2316), and a piercing member retainer (314, 1314, 2314). The assembly may further include a first film (318, 1318, 2318) covering a cavity (312A, 1312A, 2312A), thereby maintaining the aseptic condition of the cavity. The drug container may hold a fluid drug and include a pierceable seal (326, 1326, 2326). A second film (322, 1322, 2322) may cover a recess (328, 1328, 2328) formed by the seal and thereby maintain the aseptic condition of the interior of the chamber. The piercing member may be caused to pierce the first and second film and the pierceable seal to open a fluid pathway for delivery of the fluid drug through the fluid pathway connection assembly.

    Cannula insertion and retraction mechanisms
    8.
    发明授权
    Cannula insertion and retraction mechanisms 有权

    公开(公告)号：US11369736B2

    公开(公告)日：2022-06-28

    申请号：US16485245

    申请日：2018-02-13

    Applicant: AMGEN INC.

    Inventor： Erich Coiner ,  Paul Faucher ,  Adam B. McCullough ,  Antonio Ubach

    IPC: A61M5/142 ,  A61M5/158 ,  A61B17/34

    Abstract: An insertion mechanism for a wearable drug delivery device that deploys a small gauge flexible cannula with support of a coaxial rigid trocar or hollow needle. After insertion, the trocar or hollow needle is withdrawn leaving the cannula in place for drug delivery. The insertion mechanism may also include an insertion mechanism housing having a proximal and distal end, a manifold configured to fluidly connect the hollow interior of the cannula and the fluid pathway connector, and a manifold guide carrying the manifold and movable between a first position and a second position. A hub carries the trocar and is removably connected to the manifold guide. An insertion biasing member may be initially retained in an energized state between the proximal end of the insertion mechanism housing and the hub, and a retraction biasing member may be initially retained in an energized state between the hub and the manifold guide.

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