公开(公告)号：US20240301450A1

公开(公告)日：2024-09-12

申请号：US18180507

申请日：2023-03-08

Applicant: CJ CHEILJEDANG CORPORATION

Inventor： Yae Seul PARK ,  Hyang CHOI ,  Dong-Eun CHANG ,  Ji Sun LEE ,  Imsang LEE

IPC: C12P7/625 ,  C12N1/20 ,  C12N9/04 ,  C12N9/10 ,  C12N9/88 ,  C12N15/70

CPC classification number: C12P7/625 ,  C12N1/20 ,  C12N9/0006 ,  C12N9/1029 ,  C12N9/13 ,  C12N9/88 ,  C12N15/70 ,  C12R2001/19 ,  C12Y101/01035 ,  C12Y101/01157 ,  C12Y203/01009 ,  C12Y208/03001 ,  C12Y402/01017 ,  C12Y402/0112

Abstract: The present disclosure relates to a novel method for preparing poly(3-hydroxybutyrate-co-4-hydroxybutyrate), a microorganism using the biosynthetic pathway of poly(3-hydroxybutyrate-co-4-hydroxybutyrate) of the present disclosure, a composition for producing poly(3-hydroxybutyrate-co-4-hydroxybutyrate), and a method for regulating the 4-hydroxybutyrate content of poly(3-hydroxybutyrate-co-4-hydroxybutyrate).

公开(公告)号：US20240182872A1

公开(公告)日：2024-06-06

申请号：US18549838

申请日：2022-03-10

Applicant: CJ CHEILJEDANG CORPORATION

Inventor： Jin Sook CHANG ,  Ju-yeon KIM ,  Seon Hye KIM ,  Sun Hyoung CHOI ,  Byoung Hoon YOON ,  Hyung Joon KIM ,  Seung Hyun CHO ,  Jaemin LEE ,  Seo-Yun KIM ,  Imsang LEE

IPC: C12N9/10 ,  C12N1/20 ,  C12P13/06 ,  C12P13/08 ,  C12P13/12 ,  C12R1/15

CPC classification number: C12N9/1025 ,  C12N1/205 ,  C12P13/06 ,  C12P13/08 ,  C12P13/12 ,  C12R2001/15 ,  C12Y203/03001

Abstract: The present disclosure relates to a citrate synthase variant, a microorganism comprising the variant, and a method for producing L-amino acids using the microorganism.

公开(公告)号：US20220356480A1

公开(公告)日：2022-11-10

申请号：US17623231

申请日：2020-08-06

Applicant: CJ CHEILJEDANG CORPORATION

Inventor： Mina BAEK ,  Su Yon KWON ,  Imsang LEE ,  Seung-ju SON ,  Kwang Woo LEE

IPC: C12N15/77 ,  C12P13/08 ,  C12N9/02 ,  C12N9/06 ,  C12N9/88

Abstract: The present disclosure relates to a variant polypeptide having attenuated dihydrodipicolinate reductase activity and a method of producing L-threonine using the same.

公开(公告)号：US20220356479A1

公开(公告)日：2022-11-10

申请号：US17623218

申请日：2020-08-13

Applicant: CJ CHEILJEDANG CORPORATION

Inventor： Mina BAEK ,  Seung-ju SON ,  Su Yon KWON ,  Imsang LEE ,  Kwang Woo LEE

IPC: C12N15/77 ,  C12P13/08 ,  C12N9/06 ,  C12N9/02 ,  C12N9/88 ,  C40B40/02 ,  C40B40/08

Abstract: The present disclosure relates to a modified polypeptide, in which the activity of meso-diaminopimelate is weakened, and a method for producing L-threonine using the same.

公开(公告)号：US20230046561A1

公开(公告)日：2023-02-16

申请号：US17938508

申请日：2022-10-06

Applicant: CJ CHEILJEDANG CORPORATION

Inventor： Jaewon JANG ,  Kwang Woo LEE ,  Yong Uk SHIN ,  Imsang LEE

IPC: C12P13/08 ,  C12N1/20 ,  C12N9/10 ,  C12P13/06 ,  C12P13/12

Abstract: The present disclosure relates to a modified polypeptide with attenuated activity of citrate synthase and a method for producing an aspartate-derived L-amino acid using the modified polypeptide.

公开(公告)号：US20230040524A1

公开(公告)日：2023-02-09

申请号：US17779909

申请日：2020-08-04

Applicant: CJ CHEILJEDANG CORPORATION

Inventor： Chan Hong AHN ,  Ju Eun KIM ,  Hyun-jung BAE ,  Imsang LEE ,  Ji Hye LEE ,  Hayun LEE

IPC: C12N9/10 ,  C12N15/77 ,  C12P13/06

Abstract: The present disclosure relates to a modified polypeptide with attenuated activity of citrate synthase, a microorganism producing leucine comprising the modified polypeptide, and a method for producing an L-amino acid using the microorganism.

公开(公告)号：US20220396815A1

公开(公告)日：2022-12-15

申请号：US17604896

申请日：2021-03-04

Applicant: CJ CHEILJEDANG CORPORATION

Inventor： Su Jin CHOI ,  Imsang LEE ,  Heeyeong KIM ,  Byeong Soo KIM ,  Kwang Woo LEE

IPC: C12P13/14 ,  C12N15/77 ,  C12N9/00 ,  C40B40/10

Abstract: The present disclosure relates to a modified polypeptide of glutamine synthetase having enhanced activity and a method of producing L-glutamine using the same. Since production of L-glutamine may be increased by using the novel modified polypeptide without a decrease in a growth rate compared to wild-type strains having glutamine synthetase activity, the modified polypeptide may be widely used for mass production of L-glutamine.

公开(公告)号：US20240150730A1

公开(公告)日：2024-05-09

申请号：US18279519

申请日：2022-03-10

Applicant: CJ CHEILJEDANG CORPORATION

Inventor： Jin Sook CHANG ,  Seung Hyun CHO ,  Seo-Yun KIM ,  Jaemin LEE ,  Min Ji BAEK ,  Imsang LEE

IPC: C12N9/10 ,  C12N15/77 ,  C12P13/06 ,  C12P13/12 ,  C12R1/15

CPC classification number: C12N9/1025 ,  C12N15/77 ,  C12P13/06 ,  C12P13/12 ,  C12R2001/15 ,  C12Y203/03001

Abstract: The present disclosure relates to a novel citrate synthase variant, a microorganism comprising the variant, and a method for producing O-acetyl-L-homoserine and L-methionine using the microorganism.

公开(公告)号：US20230098971A1

公开(公告)日：2023-03-30

申请号：US17440172

申请日：2021-04-21

Applicant: CJ CHEILJEDANG CORPORATION

Inventor： Kyungrim KIM ,  Imsang LEE ,  Heeyeong KIM ,  Kwang Woo LEE

IPC: C12N9/88 ,  C12N15/77 ,  C12P13/06

Abstract: Provided are a novel L-threonine dehydratase variant and a method of producing L-isoleucine using the same.

公开(公告)号：US20220411774A1

公开(公告)日：2022-12-29

申请号：US17780239

申请日：2020-11-25

Applicant: CJ CHEILJEDANG CORPORATION

Inventor： Joo Hee LEE ,  Jinwoo SUNG ,  Jong-cheol SEOK ,  Ji Hyun LEE ,  Se Hoon SIM ,  Imsang LEE

IPC: C12N9/52 ,  C12N1/20 ,  A23K20/189

Abstract: The present disclosure provides a novel serine protease variant.