公开(公告)号：US20180346926A1

公开(公告)日：2018-12-06

申请号：US16049169

申请日：2018-07-30

Applicant: DOW AGROSCIENCES LLC

Inventor： Ignacio Mario Larrinua ,  Donald J. Merlo ,  Avutu S. Reddy ,  Arvind Kumar ThirumalaiswamySekhar ,  Aaron T. Woosley

IPC: C12N15/82 ,  A23D9/00 ,  C07K14/415 ,  C12N9/02 ,  C07K14/195 ,  C07K14/37 ,  C07K14/38 ,  A23L19/10 ,  A23L11/00 ,  A23L7/10 ,  C12N9/08 ,  C11B1/00 ,  C07K14/435 ,  C07K14/325

CPC classification number: C12N15/8286 ,  A23D9/00 ,  A23L7/10 ,  A23L7/198 ,  A23L11/00 ,  A23L11/05 ,  A23L19/10 ,  C07K14/195 ,  C07K14/325 ,  C07K14/37 ,  C07K14/38 ,  C07K14/415 ,  C07K14/43595 ,  C11B1/00 ,  C12N9/0065 ,  C12N9/0069 ,  C12N9/0083 ,  C12Y111/01015 ,  C12Y113/00 ,  Y02A40/162

Abstract: The invention provides synthetic nucleic acid sequences encoding proteins of interest that are particularly adapted to express well in plants. The claimed synthetic sequences utilize plant-optimized codons roughly in the same frequency at which they are utilized, on average, in genes naturally occurring in the plant species. The invention further includes synthetic DNA sequence for herbicide tolerance, water and/or heat stress tolerance, healthy oil modifications and for transformation marker genes and selectable marker genes are used. DNA construct and transgenic plants containing the synthetic sequences are taught as are methods and compositions for using the plants in agriculture.

公开(公告)号：US20160304900A1

公开(公告)日：2016-10-20

申请号：US15194925

申请日：2016-06-28

Applicant: Dow AgroSciences LLC

Inventor： Ignacio M. Larrinua ,  Donald Merlo ,  Avutu Sambi Reddy ,  Arvind Kumar ThirumalaiswamySekhar ,  Aaron T. Woosley

IPC: C12N15/82 ,  C07K14/325 ,  C07K14/37 ,  C07K14/38 ,  C07K14/415 ,  C07K14/435 ,  C12N9/02 ,  C07K14/195

CPC classification number: C12N15/8286 ,  A23D9/00 ,  A23L7/10 ,  A23L7/198 ,  A23L11/00 ,  A23L11/05 ,  A23L19/10 ,  C07K14/195 ,  C07K14/325 ,  C07K14/37 ,  C07K14/38 ,  C07K14/415 ,  C07K14/43595 ,  C11B1/00 ,  C12N9/0065 ,  C12N9/0069 ,  C12N9/0083 ,  C12Y111/01015 ,  C12Y113/00 ,  Y02A40/162

Abstract: The invention provides synthetic nucleic acid sequences encoding proteins of interest that are particularly adapted to express well in plants. The claimed synthetic sequences utilize plant-optimized codons roughly in the same frequency at which they are utilized, on average, in genes naturally occurring in the plant species. The invention further includes synthetic DNA sequence for herbicide tolerance, water and/or heat stress tolerance, healthy oil modifications and for transformation marker genes and selectable marker genes are used. DNA construct and transgenic plants containing the synthetic sequences are taught as are methods and compositions for using the plants in agriculture.

Abstract translation: 本发明提供编码感兴趣的蛋白质的合成核酸序列，其特别适于在植物中表达良好。 所要求的合成序列利用植物优化的密码子，其平均来说在天然存在于植物物种中的基因中使用大致相同的频率。 本发明还包括用于除草剂耐受性，水和/或热胁迫耐受性，健康油改性和用于转化标记基因和选择标记基因的合成DNA序列。 教导含有合成序列的DNA构建体和转基因植物，以及在农业中使用植物的方法和组合物。