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公开(公告)号：US09981935B2
公开(公告)日：2018-05-29
申请号：US14902661
申请日：2014-07-03
Applicant: DSM IP ASSETS B.V.
Inventor： Jonathan Alan Medlock , Ulla Letinois , Thomas Netscher , Werner Bonrath
IPC: C07D311/02 , C07D311/22
CPC classification number: C07D311/22 , C07B2200/09
Abstract: The present invention relates to a synthesis of chromanones or chromanes in a stereospecific matter in view of the 2-position in the chromanone or chromane ring. It has been found that this synthesis is particularly possible in the presence of a chiral compound of a specific type and of at least one Bransted acid or in the presence a specific chiral compound having a Bransted acid functional group in the molecule.
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公开(公告)号：US11724996B2
公开(公告)日：2023-08-15
申请号：US17306886
申请日：2021-05-03
Applicant: DSM IP Assets B.V.
Inventor： Ulla Letinois , Thomas Netscher , August Ruettimann
IPC: C07D311/72 , C07C45/29 , C07C45/61 , C07D311/22
CPC classification number: C07D311/72 , C07C45/29 , C07C45/298 , C07C45/61 , C07D311/22
Abstract: The present invention relates to a novel synthetic pathway for alpha-tocopherol. The invention discloses different reactions yielding some new intermediates in a very high yield and stereoselectivity.
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公开(公告)号：US10047065B2
公开(公告)日：2018-08-14
申请号：US15535477
申请日：2015-12-09
Applicant: DSM IP ASSETS B.V.
Inventor： Ulla Letinois , Thomas Netscher
Abstract: The present invention relates to a method of preparing chromanes from 2,5-dimethylfuran and substituted alkynes comprising an long chain unsaturated alkyl group as substituent in the alpha position of a substituted phenol followed by oxidation, reduction and acid ring closure. It is particularly advantageous to use 2,5-dimethylfuran as this offers an ecological beneficial synthesis of β-tocopherol.
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4.发明授权公开(公告)号：US09809565B2
公开(公告)日：2017-11-07
申请号：US14902871
申请日：2014-07-03
Applicant: DSM IP ASSETS B.V.
Inventor： Ulla Letinois , Thomas Netscher , Stephan Ackermann
IPC: C07D311/00 , C07D311/22
CPC classification number: C07D311/22
Abstract: The present invention relates to a synthesis of chromanones or chromanes in a stereospecific matter in view of the 2-position in the chromanone or chromane ring. It has been found that this synthesis is particularly possible in the presence of a chiral compound of formula of a specific type and of at least one urea or thiourea.
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Patent Agency Ranking
5.发明授权公开(公告)号：US10815178B2
公开(公告)日：2020-10-27
申请号：US16720580
申请日：2019-12-19
Applicant: DSM IP Assets B.V.
Inventor： Ulla Letinois , Stephan Ackermann , Jonathan Alan Medlock , Hajo Lehmann
IPC: C07C41/30 , C07C37/07 , C07C37/50 , C07C43/178 , C07D311/72 , C07C46/08 , C07C41/36 , B01J31/18 , B01J31/22 , B01J31/24
Abstract: The present invention relates to a method of preparing ortho substituted phenols from 2,5-dimethylfuran and propargyl ethers in the presence of a gold(I) complex. It is particularly advantageous to use 2,5-dimethylfuran as this offers an ecological beneficial synthesis of said ortho substituted phenols.
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公开(公告)号：US10005710B2
公开(公告)日：2018-06-26
申请号：US15129948
申请日：2015-03-26
Applicant: DSM IP ASSETS B.V.
Inventor： Werner Bonrath , Raphael Beumer , Ulla Letinois
CPC classification number: C07C45/512 , B01J31/2404 , B01J2531/18 , C07C49/543
Abstract: The present invention relates to an improved method for producing of 1-(5,5-dimethylcyclohex-1-en-1-yl)ethanone and 1-(5,5-dimethylcyclohex-6-en-1-yl)ethanone.
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公开(公告)号：US09815809B2
公开(公告)日：2017-11-14
申请号：US14902662
申请日：2014-07-03
Applicant: DSM IP ASSETS B.V.
Inventor： Ulla Letinois , Thomas Netscher
IPC: C07D311/00 , C07D311/22
CPC classification number: C07D311/22 , C07B2200/09
Abstract: The present invention relates to a synthesis of chromanones or chromanes in a stereospecific matter in view of the 2-position in the chromanone or chromane ring. It has been found that this synthesis is particularly possible in the presence of a chiral compound of formula of a specific type and of at least one phenol or thiophenol.
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公开(公告)号：US11987539B2
公开(公告)日：2024-05-21
申请号：US17047883
申请日：2019-04-23
Applicant: DSM IP ASSETS B.V.
Inventor： Stefan Karl Laeuger , Ulla Letinois , Peter Riebel
IPC: C07C203/04 , A23K20/105 , A23K20/158 , A23K50/10
CPC classification number: C07C203/04 , A23K20/105 , A23K20/158 , A23K50/10
Abstract: The present invention relates to novel dicarboxylic diesters as well as the use thereof as for inhibiting the methane production in ruminants.
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公开(公告)号：US09902674B2
公开(公告)日：2018-02-27
申请号：US15114144
申请日：2015-01-27
Applicant: DSM IP ASSETS B.V.
Inventor： Werner Bonrath , Ulla Letinois , Thomas Netscher
CPC classification number: C07C37/14 , B01J31/2404 , B01J2231/48 , B01J2531/18 , C07C39/07
Abstract: The present invention relates to a new method to produce 2,5-dimethylphenol (2,5-DMP).
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