公开(公告)号：US20240252074A1

公开(公告)日：2024-08-01

申请号：US18425940

申请日：2024-01-29

Applicant: Dexcom, Inc.

Inventor： Sebastian Böhm ,  Anna Harley-Trochimczyk ,  Daiting Rong ,  Rui Ma ,  Wenjie Lan ,  Minglian Shi ,  Disha Sheth ,  Nicholas Kalfas ,  Vincent Crabtree ,  Kamuran Turksoy

IPC: A61B5/1495 ,  A61B5/00 ,  A61B5/0537 ,  A61B5/145 ,  A61B5/1473 ,  A61B5/1486 ,  G01N27/02 ,  G01N27/22 ,  G01N27/24 ,  G01N33/487

CPC classification number: A61B5/1495 ,  A61B5/0537 ,  A61B5/14532 ,  A61B5/14546 ,  A61B5/1473 ,  A61B5/1486 ,  A61B5/14865 ,  A61B5/6844 ,  G01N27/221 ,  G01N27/24 ,  G01N33/48707 ,  A61B5/0004 ,  A61B5/0031 ,  A61B2560/0223 ,  A61B2560/0252 ,  A61B2560/0276 ,  G01N27/026

Abstract: Various examples are directed to systems and methods of and using analyte sensors. An example analyte sensor system comprises an analyte sensor and a hardware device in communication with the analyte sensor. The hardware device may be configured to perform operations comprising applying a first bias voltage to the analyte sensor, the first bias voltage less than an operational bias voltage of the analyte sensor, measuring a first current at the analyte sensor when the first bias voltage is applied, and applying a second bias voltage to the analyte sensor. The operations may further comprise measuring a second current at the analyte sensor when the second bias voltage is applied, detecting a plateau bias voltage using the first current and the second current, determining that the plateau bias voltage is less than a plateau bias voltage threshold, and executing a responsive action at the analyte sensor.

公开(公告)号：US11974845B2

公开(公告)日：2024-05-07

申请号：US17368541

申请日：2021-07-06

Applicant: DexCom, Inc.

Inventor： Rui Ma ,  Naresh C. Bhavaraju ,  Thomas Stuart Hamilton ,  Jonathan Hughes ,  Jeff Jackson ,  David I-Chun Lee ,  Peter C. Simpson ,  Stephen J. Vanslyke

IPC: A61B5/1495 ,  A61B5/145 ,  G01N33/66 ,  A61B5/1486

CPC classification number: A61B5/1495 ,  A61B5/14532 ,  G01N33/66 ,  A61B5/14865

Abstract: Systems and methods are disclosed which provide for a “factory-calibrated” sensor. In doing so, the systems and methods include predictive prospective modeling of sensor behavior, and also include predictive modeling of physiology. With these two correction factors, a consistent determination of sensitivity can be achieved, thus achieving factory calibration.

公开(公告)号：US11484232B2

公开(公告)日：2022-11-01

申请号：US16254080

申请日：2019-01-22

Applicant: DexCom, Inc.

Inventor： Anna Claire Harley-Trochimczyk ,  Sebastian Böhm ,  Rui Ma ,  Disha B. Sheth ,  Minglian Shi ,  Kamuran Turksoy

IPC: A61B5/00 ,  A61B5/1495 ,  A61B5/0205 ,  A61B5/145 ,  A61B5/1486 ,  A61B5/01 ,  G16H50/20 ,  G01N27/327 ,  A61B5/024 ,  A61B5/11

Abstract: This document discusses, among other things, systems and methods to compensate for the effects of temperature on sensors, such as analyte sensor. An example method may include determining a temperature-compensated glucose concentration level by receiving a temperature signal indicative of a temperature parameter of an external component, receiving a glucose signal indicative of an in vivo glucose concentration level, and determining a compensated glucose concentration level based on the glucose signal, the temperature signal, and a delay parameter.

公开(公告)号：US20200205705A1

公开(公告)日：2020-07-02

申请号：US16728945

申请日：2019-12-27

Applicant: DexCom, Inc.

Inventor： Ted Tang Lee ,  Anna Leigh Davis ,  Peter C. Simpson ,  Liang Wang ,  Shanger Wang ,  Jiong Zou ,  Stephen J. Vanslyke ,  Rui Ma ,  Wenjie Lan

IPC: A61B5/145 ,  A61B5/1495 ,  A61B5/1473

Abstract: Various examples described herein are directed to systems, apparatuses, and methods for mitigating break-in in an analyte sensor. An example analyte sensor system comprises an analyte sensor applicator comprising a needle; an analyte sensor comprising at least a working electrode and a reference electrode, the analyte sensor positioned at least partially within a lumen of the needle; and a hydrating agent positioned within the lumen of the needle to at least partially hydrate the needle.

公开(公告)号：US10362975B2

公开(公告)日：2019-07-30

申请号：US15394327

申请日：2016-12-29

Applicant: DexCom, Inc.

Inventor： Rui Ma ,  Naresh C. Bhavaraju ,  Thomas Stuart Hamilton ,  Jonathan Hughes ,  Jeff Jackson ,  David I-Chun Lee ,  Peter C. Simpson ,  Stephen J. Vanslyke

IPC: A61B5/1495 ,  G01N33/66 ,  A61B5/145 ,  A61B5/1486

Abstract: Systems and methods are disclosed which provide for a “factory-calibrated” sensor. In doing so, the systems and methods include predictive prospective modeling of sensor behavior, and also include predictive modeling of physiology. With these two correction factors, a consistent determination of sensitivity can be achieved, thus achieving factory calibration.

公开(公告)号：US20190227022A1

公开(公告)日：2019-07-25

申请号：US16254080

申请日：2019-01-22

Applicant: DexCom, Inc.

Inventor： Anna Claire Harley-Trochimczyk ,  Sebastian Böhm ,  Rui Ma ,  Disha B. Sheth ,  Minglian Shi ,  Kamuran Turksoy

IPC: G01N27/327 ,  A61B5/145 ,  A61B5/1486 ,  A61B5/1495

Abstract: This document discusses, among other things, systems and methods to compensate for the effects of temperature on sensors, such as analyte sensor. An example method may include determining a temperature-compensated glucose concentration level by receiving a temperature signal indicative of a temperature parameter of an external component, receiving a glucose signal indicative of an in vivo glucose concentration level, and determining a compensated glucose concentration level based on the glucose signal, the temperature signal, and a delay parameter.

公开(公告)号：US20170188906A1

公开(公告)日：2017-07-06

申请号：US15394327

申请日：2016-12-29

Applicant: DexCom, Inc.

Inventor： Rui Ma ,  Naresh C. Bhavaraju ,  Thomas Stuart Hamilton ,  Jonathan Hughes ,  Jeff Jackson ,  David I-Chun Lee ,  Peter C. Simpson ,  Stephen J. Vanslyke

IPC: A61B5/1495 ,  G01N33/66 ,  A61B5/145

CPC classification number: A61B5/1495 ,  A61B5/14532 ,  A61B5/14865 ,  G01N33/66

Abstract: Systems and methods are disclosed which provide for a “factory-calibrated” sensor. In doing so, the systems and methods include predictive prospective modeling of sensor behavior, and also include predictive modeling of physiology. With these two correction factors, a consistent determination of sensitivity can be achieved, thus achieving factory calibration.

公开(公告)号：US20240423518A1

公开(公告)日：2024-12-26

申请号：US18828569

申请日：2024-09-09

Applicant: Dexcom, Inc.

Inventor： Sebastian Böhm ,  Anna Harley-Trochimczyk ,  Daiting Rong ,  Rui Ma ,  Wenjie Lan ,  Minglian Shi ,  Disha Sheth

IPC: A61B5/1495 ,  A61B5/00 ,  A61B5/0537 ,  A61B5/145 ,  A61B5/1473 ,  A61B5/1486 ,  G01N27/02 ,  G01N27/22 ,  G01N27/24 ,  G01N33/487

Abstract: Various examples are directed to systems and methods for operating an analyte sensor system using sensor electronics. An example method may comprise applying a bias voltage change to an analyte sensor bias voltage and measuring a current value for each of a plurality of time periods after application of the bias voltage change. The example method may also comprise determining an estimated impedance using the current values for the plurality of time periods and determining a characteristic of the analyte sensor using the estimated impedance. The example method may further comprise receiving from the analyte sensor a signal indicative of an analyte concentration, and determining an estimated analyte concentration level using the determined characteristic of the analyte sensor and the received signal.

公开(公告)号：US11714060B2

公开(公告)日：2023-08-01

申请号：US16402124

申请日：2019-05-02

Applicant: DexCom, Inc.

Inventor： Naresh C. Bhavaraju ,  Becky L. Clark ,  Vincent P. Crabtree ,  Chris W. Dring ,  Arturo Garcia ,  Jason Halac ,  Jonathan Hughes ,  Jeff Jackson ,  Lauren Hruby Jepson ,  David I-Chun Lee ,  Ted Tang Lee ,  Rui Ma ,  Zebediah L. McDaniel ,  Jason Mitchell ,  Andrew Attila Pal ,  Daiting Rong ,  Disha B. Sheth ,  Peter C. Simpson ,  Stephen J. Vanslyke ,  Matthew D. Wightlin ,  Anna Leigh Davis ,  Hari Hampapuram ,  Aditya Sagar Mandapaka ,  Alexander Leroy Teeter ,  Liang Wang

IPC: G01N27/32 ,  G01N27/327 ,  A61B5/145 ,  A61B5/1495

CPC classification number: G01N27/3274 ,  A61B5/1495 ,  A61B5/14532 ,  A61B2560/0223

Abstract: Systems and methods are provided that address the need to frequently calibrate analyte sensors, according to implementation. In more detail, systems and methods provide a preconnected analyte sensor system that physically combines an analyte sensor to measurement electronics during the manufacturing phase of the sensor and in some cases in subsequent life phases of the sensor, so as to allow an improved recognition of sensor environment over time to improve subsequent calibration of the sensor.

公开(公告)号：US11484233B2

公开(公告)日：2022-11-01

申请号：US16254213

申请日：2019-01-22

Applicant: DexCom, Inc.

Inventor： Anna Claire Harley-Trochimczyk ,  Sebastian Böhm ,  Rui Ma ,  Disha B. Sheth ,  Minglian Shi ,  Kamuran Turksoy

IPC: A61B5/1495 ,  A61B5/0205 ,  A61B5/145 ,  A61B5/1486 ,  A61B5/00 ,  A61B5/01 ,  G16H50/20 ,  G01N27/327 ,  A61B5/024 ,  A61B5/11

Abstract: This document discusses, among other things, systems and methods to compensate for the effects of temperature on sensors, such as analyte sensor. An example method may include determining a temperature-compensated glucose concentration level by receiving a temperature signal indicative of a temperature parameter of an external component, receiving a glucose signal indicative of an in vivo glucose concentration level, and determining a compensated glucose concentration level based on the glucose signal, the temperature signal, and a delay parameter.