公开(公告)号：US11304631B2

公开(公告)日：2022-04-19

申请号：US16537400

申请日：2019-08-09

Applicant: DexCom, Inc.

Inventor： Jack Pryor ,  Sebastian Böhm ,  David DeRenzy ,  Jason Halac ,  Daniel S. Kline ,  Phong Lieu ,  Adam J. Livingston ,  Steve Masterson ,  Paul V. Neale ,  Peter C. Simpson ,  Antonio Joao Ubach

IPC: A61B5/00 ,  A61B5/145

Abstract: The present embodiments relate generally to systems and methods for measuring an analyte in a host. More particularly, the present embodiments provide sensor applicators and methods of use with pushbutton activation that implant the sensor, withdraw the insertion needle, engage the transmitter with the housing, and disengage the applicator from the housing, all in one smooth motion. Some embodiments contemplate engagement of the transmitter with the housing after release of the applicator.

公开(公告)号：US20210353185A1

公开(公告)日：2021-11-18

申请号：US17444148

申请日：2021-07-30

Applicant: DexCom, Inc.

Inventor： Peter C. Simpson ,  Robert J. Boock ,  Paul V. Neale ,  Sebastian Böhm ,  Matthew D. Wightlin ,  Jack Pryor ,  Jason Mitchell ,  Jeff Jackson ,  Kaushik Patel ,  Antonio C. Llevares

IPC: A61B5/1473 ,  A61B5/1486 ,  B05C3/12 ,  B05C3/02 ,  A61B5/145 ,  B05C3/10

Abstract: Analyte sensors and methods of manufacturing same are provided, including analyte sensors comprising multi-axis flexibility. For example, a multi-electrode sensor system 800 comprising two working electrodes and at least one reference/counter electrode is provided. The sensor system 800 comprises first and second elongated bodies E1, E2, each formed of a conductive core or of a core with a conductive layer deposited thereon, insulating layer 810 that separates the conductive layer 820 from the elongated body, a membrane layer deposited on top of the elongated bodies E1, E2, and working electrodes 802′, 802″ formed by removing portions of the conductive layer 820 and the insulating layer 810, thereby exposing electroactive surface of the elongated bodies E1, E2.

公开(公告)号：US10682084B2

公开(公告)日：2020-06-16

申请号：US16405887

申请日：2019-05-07

Applicant: DexCom, Inc.

Inventor： Sebastian Böhm ,  Daiting Rong ,  Peter C. Simpson

IPC: G08B21/20 ,  A61B5/1495 ,  G01N27/327 ,  A61B5/145 ,  A61B5/1486 ,  A61B5/00 ,  G01D18/00 ,  G01N27/02 ,  G01N33/49 ,  A61B5/1473

Abstract: Systems and methods for processing sensor data and self-calibration are provided. In some embodiments, systems and methods are provided which are capable of calibrating a continuous analyte sensor based on an initial sensitivity, and then continuously performing self-calibration without using, or with reduced use of, reference measurements. In certain embodiments, a sensitivity of the analyte sensor is determined by applying an estimative algorithm that is a function of certain parameters. Also described herein are systems and methods for determining a property of an analyte sensor using a stimulus signal. The sensor property can be used to compensate sensor data for sensitivity drift, or determine another property associated with the sensor, such as temperature, sensor membrane damage, moisture ingress in sensor electronics, and scaling factors.

公开(公告)号：US10588557B2

公开(公告)日：2020-03-17

申请号：US15213259

申请日：2016-07-18

Applicant: DexCom, Inc.

Inventor： Michael J. Estes ,  Stephen J. Vanslyke ,  Apurv Ullas Kamath ,  Thomas A. Peyser ,  Lucas Bohnett ,  Aarthi Mahalingam ,  Arturo Garcia ,  Peter C. Simpson ,  Anna Leigh Davis ,  Sebastian Böhm

IPC: A61B5/00 ,  A61B5/145 ,  A61B5/1495 ,  G01D3/02 ,  G06F19/00

Abstract: Systems and methods for applying time-dependent algorithmic compensation functions to data output from a continuous analyte sensor. Some embodiments determine a time since sensor implantation and/or whether a newly initialized sensor has been used previously, for example, by initializing a sensor, acquiring sensor data, using the sensor, to measure an analyte level in the host's body over a first interval based on a first elapsed time since the sensor was implanted, determining whether the sensor has been previously used in a previous sensor session or the sensor is a new sensor, and upon determining the sensor is a new sensor, adjusting the acquired sensor data to compensate for sensor drift of the new sensor by applying a first set of time-dependent algorithmic functions to the sensor data associated with the first interval.

公开(公告)号：US20200037935A1

公开(公告)日：2020-02-06

申请号：US16586434

申请日：2019-09-27

Applicant: DexCom, Inc.

Inventor： Sebastian Böhm ,  Daiting Rong ,  Peter C. Simpson

IPC: A61B5/1495 ,  G01N27/327 ,  A61B5/145 ,  A61B5/1486 ,  A61B5/00 ,  G01D18/00 ,  G01N27/02 ,  G01N33/49 ,  A61B5/1473

Abstract: Systems and methods for processing sensor data and self-calibration are provided. In some embodiments, systems and methods are provided which are capable of calibrating a continuous analyte sensor based on an initial sensitivity, and then continuously performing self-calibration without using, or with reduced use of, reference measurements. In certain embodiments, a sensitivity of the analyte sensor is determined by applying an estimative algorithm that is a function of certain parameters. Also described herein are systems and methods for determining a property of an analyte sensor using a stimulus signal. The sensor property can be used to compensate sensor data for sensitivity drift, or determine another property associated with the sensor, such as temperature, sensor membrane damage, moisture ingress in sensor electronics, and scaling factors.

公开(公告)号：US20200022626A1

公开(公告)日：2020-01-23

申请号：US16586389

申请日：2019-09-27

Applicant: DexCom, Inc.

Inventor： Sebastian Böhm ,  Daiting Rong ,  Peter C. Simpson

IPC: A61B5/1495 ,  A61B5/00 ,  G01D18/00 ,  G01N33/49 ,  G01N27/327 ,  A61B5/1486 ,  A61B5/1473 ,  A61B5/145 ,  G01N27/02

Abstract: Systems and methods for processing sensor data and self-calibration are provided. In some embodiments, systems and methods are provided which are capable of calibrating a continuous analyte sensor based on an initial sensitivity, and then continuously performing self-calibration without using, or with reduced use of, reference measurements. In certain embodiments, a sensitivity of the analyte sensor is determined by applying an estimative algorithm that is a function of certain parameters. Also described herein are systems and methods for determining a property of an analyte sensor using a stimulus signal. The sensor property can be used to compensate sensor data for sensitivity drift, or determine another property associated with the sensor, such as temperature, sensor membrane damage, moisture ingress in sensor electronics, and scaling factors.

公开(公告)号：US20190320949A1

公开(公告)日：2019-10-24

申请号：US16460943

申请日：2019-07-02

Applicant: DexCom, Inc.

Inventor： Sebastian Böhm ,  Daiting Rong ,  Peter C. Simpson

IPC: A61B5/1495 ,  G01N33/49 ,  A61B5/1486 ,  A61B5/145 ,  A61B5/00 ,  A61B5/1473 ,  G01N27/02 ,  G01N27/327 ,  G01D18/00

Abstract: Systems and methods for processing sensor data and self-calibration are provided. In some embodiments, systems and methods are provided which are capable of calibrating a continuous analyte sensor based on an initial sensitivity, and then continuously performing self-calibration without using, or with reduced use of, reference measurements. In certain embodiments, a sensitivity of the analyte sensor is determined by applying an estimative algorithm that is a function of certain parameters. Also described herein are systems and methods for determining a property of an analyte sensor using a stimulus signal. The sensor property can be used to compensate sensor data for sensitivity drift, or determine another property associated with the sensor, such as temperature, sensor membrane damage, moisture ingress in sensor electronics, and scaling factors.

公开(公告)号：US20190209057A1

公开(公告)日：2019-07-11

申请号：US16359765

申请日：2019-03-20

Applicant: DexCom, Inc.

Inventor： Peter C. Simpson ,  Jennifer Blackwell ,  Sebastian Böhm

IPC: A61B5/1473 ,  A61B5/1486 ,  A61B5/00 ,  A61B17/34 ,  A61B5/145

CPC classification number: A61B5/1473 ,  A61B5/14503 ,  A61B5/14532 ,  A61B5/14865 ,  A61B5/4839 ,  A61B5/6848 ,  A61B17/3468 ,  A61B2017/00004

Abstract: Sensor devices including dissolvable tissue-piercing tips are provided. The sensor devices can be used in conjunction with dissolvable needles configured for inserting the sensor devices into a host. Hardening agents for strengthening membranes on sensor devices are also provided. Methods of using and fabricating sensor devices are also provided.

公开(公告)号：US10238323B2

公开(公告)日：2019-03-26

申请号：US14717904

申请日：2015-05-20

Applicant: DexCom, Inc.

Inventor： Stephen J. Vanslyke ,  Naresh C. Bhavaraju ,  Sebastian Böhm ,  Leif N. Bowman ,  Michael J. Estes ,  Arturo Garcia ,  Apurv Ullas Kamath ,  Andrew Attila Pal ,  Thomas A. Peyser ,  Anna Leigh Rack-Gomer ,  Daiting Rong ,  Disha B. Sheth ,  Peter C. Simpson ,  Dmytro Sokolovsky

IPC: A61B5/00 ,  A61B5/1495 ,  A61B5/01 ,  A61B5/11 ,  A61B5/053 ,  A61B5/145 ,  A61B5/1486 ,  A61B5/1473 ,  A61M5/172 ,  G06F19/00

Abstract: Systems and methods disclosed here provide ways to discriminate fault types encountered in analyte sensors and systems and further provide ways to process such discriminated faults responsively based on sensor data, clinical context information, and other data about the patient or patient's environment. The systems and methods thus employ clinical context in detecting and/or responding to errors or faults associated with an analyte sensor system, and discriminating the type of fault, and its root cause, particularly as fault dynamics can appear similar to the dynamics of physiological systems, emphasizing the importance of discriminating the fault and providing appropriate responsive processing. Thus, the disclosed systems and methods consider the context of the patient's health condition or state in determining how to respond to the fault.

公开(公告)号：US20180271415A1

公开(公告)日：2018-09-27

申请号：US15993006

申请日：2018-05-30

Applicant: DexCom, Inc.

Inventor： Sebastian Böhm ,  Daiting Rong ,  Peter C. Simpson

IPC: A61B5/1495 ,  A61B5/145 ,  A61B5/00 ,  A61B5/1473 ,  A61B5/1486 ,  G01N27/327 ,  G01N27/02 ,  G01N33/49 ,  G01D18/00

CPC classification number: A61B5/1495 ,  A61B5/14503 ,  A61B5/1451 ,  A61B5/14517 ,  A61B5/14532 ,  A61B5/14546 ,  A61B5/1473 ,  A61B5/1486 ,  A61B5/7257 ,  A61B5/7267 ,  A61B2560/0276 ,  G01D18/00 ,  G01N27/026 ,  G01N27/3274 ,  G01N33/49 ,  H05K999/00 ,  H05K999/99

Abstract: Systems and methods for processing sensor data and self-calibration are provided. In some embodiments, systems and methods are provided which are capable of calibrating a continuous analyte sensor based on an initial sensitivity, and then continuously performing self-calibration without using, or with reduced use of, reference measurements. In certain embodiments, a sensitivity of the analyte sensor is determined by applying an estimative algorithm that is a function of certain parameters. Also described herein are systems and methods for determining a property of an analyte sensor using a stimulus signal. The sensor property can be used to compensate sensor data for sensitivity drift, or determine another property associated with the sensor, such as temperature, sensor membrane damage, moisture ingress in sensor electronics, and scaling factors.