专利检索 ap:("GODX, INC" OR "THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HUMAN SERVICES") AND inv:"Chang Hee Kim" 第 1 页

1.

发明申请
POINT OF NEED TESTING DEVICE AND METHODS OF USE THEREOF 审中-公开

公开(公告)号：US20180148774A1

公开(公告)日：2018-05-31

申请号：US15574750

申请日：2016-05-16

申请人： GODX, INC , THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HUMAN SERVICES

发明人： Chang Hee Kim , Wendy A. Henderson , Sarah K. Abey , Nicolaas H. Fourie , Eric G. Ferguson

IPC分类号： C12Q1/6834 , B01L3/00 , C12Q1/70 , C12Q1/6888 , C12Q1/6825

CPC分类号： C12Q1/6834 , B01L3/5023 , B01L2200/141 , B01L2300/069 , B01L2400/0406 , C12Q1/00 , C12Q1/6816 , C12Q1/6825 , C12Q1/6888 , C12Q1/689 , C12Q1/701 , G01N15/06 , G01N15/1056 , G01N15/1463 , G01N15/1484 , G01N33/487 , G01N2015/0693 , G01N2015/1006 , Y02A50/51 , Y02A50/52 , Y02A50/53 , Y02A50/58 , C12Q2565/625

摘要： The present invention relates to the rapid and electricity-free, point-of-care, multiplexed detection and quantification of at least one or more nucleic acid sequences from nucleic acids corresponding to a plurality of pathogens or biomarkers using a micropatterned lateral flow device. Rapid and molecular-level sensitive differential diagnosis of a disease condition may be enabled without the need for a delayed laboratory test so that timely treatment can be administered.

2.

发明授权
Rapid nucleic acids separation and sample preparation via hollow-centered silica microsphere 有权

公开(公告)号：US11746372B2

公开(公告)日：2023-09-05

申请号：US16768802

申请日：2018-12-03

申请人： GoDX, inc. , The United States of America, as Represented by the Secretary, Department of Health and Human Services

发明人： Chang Hee Kim , Lichen Xiang , Wendy A. Henderson , Xiao Jiang

IPC分类号： C12Q1/6806 , C12N15/10 , C12Q1/6865

CPC分类号： C12Q1/6806 , C12N15/1006 , C12Q1/6865 , C12Q2527/125 , C12Q2531/113 , C12Q2531/143 , C12Q2563/155

摘要： Disclosed herein are method for separating, amplifying, or detecting a nucleic acid from a sample may comprise contacting a sample lysate with a plurality of buoyant, inorganic, nucleic-acid-capture microspheres. The nucleic-acid-capture microspheres may comprise unicellular hollow microspheres having a diameter between 5 and 300 μm and/or a true particle density between 0.05 and 0.60 grams/cm3. The microspheres may comprise hollow soda-lime-borosilicate microspheres. In some embodiments, the microspheres comprises hollow soda-lime-borosilicate microspheres surrounded by an amorphous silica shell. Also disclosed are kits for performing the methods.