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公开(公告)号：US20120094552A1
公开(公告)日：2012-04-19
申请号：US13265365
申请日：2010-04-13
申请人： Heinz Reibke , Rudolf Merz , Guohua Chen , Carsten Lückheide
发明人： Heinz Reibke , Rudolf Merz , Guohua Chen , Carsten Lückheide
IPC分类号： H01R13/02
CPC分类号： H01R13/748 , H01R9/18
摘要： An electric terminal for leading a conductor through a wall (1), comprising a first terminal piece (2) to be mounted on a first side (3) of the wall (1), and a second terminal piece (4) to be mounted on the second side (5) of the wall (1) is provided. The second terminal piece (4) or the first terminal piece (2) can be fastened to the wall (1) using a fastening means (6) that can be inserted through the wall (1) into the first terminal piece (2) or the second terminal piece (4) from the first side (3) or the second side (5) of the wall (1), and/or the fastening means (6) can be interlocked with the second terminal piece (4) or the first terminal piece (2) in such a way that to the second terminal piece (4) or the first terminal piece (2) can be fastened to the wall (1) from the second side (5) or the first side (3) of the wall (1). According to the invention, such an electric terminal for leading a conductor through a wall (1) can be fastened to the wall (1) in a particularly simple fashion.
摘要翻译： 一种用于引导导体穿过壁（1）的电端子，包括要安装在壁（1）的第一侧（3）上的第一端子件（2）和待安装的第二端子件（4） 在壁（1）的第二侧（5）上。 第二端子件（4）或第一端子件（2）可以使用能够穿过壁（1）插入到第一端子件（2）中的紧固装置（6）而紧固到壁（1），或 来自第一侧（3）或壁（1）的第二侧（5）的第二端子件（4）和/或紧固装置（6）可以与第二端子件（4）或 第一端子片（2）以从第二侧（5）或第一侧（3）可以将第二端子片（4）或第一端子片（2）固定到壁（1） 的墙（1）。 根据本发明，用于引导导体穿过壁（1）的这种电端子可以以特别简单的方式固定到壁（1）上。
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公开(公告)号：US08579657B2
公开(公告)日：2013-11-12
申请号：US13265038
申请日：2010-04-13
申请人： Heinz Reibke , Rudolf Merz , Guohua Chen , Dennis Sprenger
发明人： Heinz Reibke , Rudolf Merz , Guohua Chen , Dennis Sprenger
IPC分类号： H01R13/60
摘要： The invention relates to an electric terminal for leading a conductor through a wall, comprising a first terminal piece (1) to be mounted on one side of the wall, and a second terminal piece (2) to be mounted on the other side of the wall. The first terminal piece (1) has a first connecting element (5) and a holding element (7) for positioning the first connecting element (5), while the second terminal piece (2) has a busbar (4) to be electrically connected to the first connecting element (5). According to the invention, the first connecting element (5) in such an electric terminal for leading a conductor through a wall can be connected to the conductor and/or the busbar (4) in a particularly simple fashion because the first connecting element (5) is positioned in the first terminal piece (1) by the holding element (7).
摘要翻译： 本发明涉及一种用于将导体引导通过壁的电端子，其包括将安装在壁的一侧的第一端子件（1）和安装在壁的另一侧上的第二端子件（2） 壁。 第一端子件（1）具有用于定位第一连接元件（5）的第一连接元件（5）和保持元件（7），而第二端子件（2）具有电连接的汇流条（4） 到第一连接元件（5）。 根据本发明，用于引导导体穿过壁的这种电端子中的第一连接元件（5）可以以特别简单的方式连接到导体和/或母线（4），因为第一连接元件（5） ）通过保持元件（7）定位在第一端子件（1）中。
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公开(公告)号：US20120100740A1
公开(公告)日：2012-04-26
申请号：US13265038
申请日：2010-04-13
申请人： Heinz Reibke , Rudolf Merz , Guohua Chen , Dennis Sprenger
发明人： Heinz Reibke , Rudolf Merz , Guohua Chen , Dennis Sprenger
IPC分类号： H01R13/621
摘要： The invention relates to an electric terminal for leading a conductor through a wall, comprising a first terminal piece (1) to be mounted on one side of the wall, and a second terminal piece (2) to be mounted on the other side of the wall. The first terminal piece (1) has a first connecting element (5) and a holding element (7) for positioning the first connecting element (5), while the second terminal piece (2) has a busbar (4) to be electrically connected to the first connecting element (5). According to the invention, the first connecting element (5) in such an electric terminal for leading a conductor through a wall can be connected to the conductor and/or the busbar (4) in a particularly simple fashion because the first connecting element (5) is positioned in the first terminal piece (1) by the holding element (7).
摘要翻译： 本发明涉及一种用于将导体引导通过壁的电端子，其包括将安装在壁的一侧的第一端子件（1）和安装在壁的另一侧上的第二端子件（2） 壁。 第一端子件（1）具有用于定位第一连接元件（5）的第一连接元件（5）和保持元件（7），而第二端子件（2）具有电连接的汇流条（4） 到第一连接元件（5）。 根据本发明，用于引导导体穿过壁的这种电端子中的第一连接元件（5）可以以特别简单的方式连接到导体和/或母线（4），因为第一连接元件（5） ）通过保持元件（7）定位在第一端子件（1）中。
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公开(公告)号：US08771003B2
公开(公告)日：2014-07-08
申请号：US13265365
申请日：2010-04-13
申请人： Heinz Reibke , Rudolph Merz , Guohua Chen , Carsten Lueckheide
发明人： Heinz Reibke , Rudolph Merz , Guohua Chen , Carsten Lueckheide
IPC分类号： H01R13/62
CPC分类号： H01R13/748 , H01R9/18
摘要： An electric terminal for leading a conductor through a wall (1), comprising a first terminal piece (2) to be mounted on a first side (3) of the wall (1), and a second terminal piece (4) to be mounted on the second side (5) of the wall (1) is provided. The second terminal piece (4) or the first terminal piece (2) can be fastened to the wall (1) using a fastening means (6) that can be inserted through the wall (1) into the first terminal piece (2) or the second terminal piece (4) from the first side (3) or the second side (5) of the wall (1), and/or the fastening means (6) can be interlocked with the second terminal piece (4) or the first terminal piece (2) in such a way that the second terminal piece (4) or the first terminal piece (2) can be fastened to the wall (1) from the second side (5) or the first side (3) of the wall (1). According to the invention, such an electric terminal for leading a conductor through a wall (1) can be fastened to the wall (1) in a particularly simple fashion.
摘要翻译： 一种用于引导导体穿过壁（1）的电端子，包括要安装在壁（1）的第一侧（3）上的第一端子件（2）和待安装的第二端子件（4） 在壁（1）的第二侧（5）上。 第二端子件（4）或第一端子件（2）可以使用能够穿过壁（1）插入到第一端子件（2）中的紧固装置（6）而紧固到壁（1），或 来自第一侧（3）或壁（1）的第二侧（5）的第二端子件（4）和/或紧固装置（6）可以与第二端子件（4）或 第一端子片（2），使得第二端子片（4）或第一端子片（2）能够从第二侧（5）或第一侧（3）紧固到壁（1） 墙（1）。 根据本发明，用于引导导体穿过壁（1）的这种电端子可以以特别简单的方式固定到壁（1）上。
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5.发明授权公开(公告)号：US09687641B2
公开(公告)日：2017-06-27
申请号：US13101071
申请日：2011-05-04
CPC分类号： A61K9/0021 , A61K38/29 , A61K47/22 , A61K47/26 , A61K47/34 , A61K47/36 , A61M37/0015 , A61M2037/0023 , A61M2037/0061
摘要： A method and a drug delivery system for transdermally administering parathyroid hormone (PTH) in a pulsatile fashion are provided, where the drug delivery system comprises an array of microprojections each comprising PTH.
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公开(公告)号：US20130108681A1
公开(公告)日：2013-05-02
申请号：US13593371
申请日：2012-08-23
IPC分类号： A61K9/00
CPC分类号： A61K38/1858 , A61K9/0002 , A61K9/0024 , A61K9/1617 , A61K31/445 , A61K38/27 , A61K45/06 , A61K47/10 , A61K47/14 , A61K47/34
摘要： Injectable depot compositions are provided that include a bioerodible, biocompatible polymer, a solvent having a miscibility in water of less than or equal to 7 wt. % at 25° C., in an amount effective to plasticize the polymer and form a gel therewith, a thixotropic agent, and a beneficial agent. The solvent comprises an aromatic alcohol, an ester of an aromatic acid, an aromatic ketone, or mixtures thereof. The compositions have substantially improved the shear thinning behavior and reduced injection force, rendering the compositions readily implanted beneath a patients body surface by injection.
摘要翻译： 提供了可注射的储库组合物，其包括生物可腐蚀的生物相容性聚合物，在水中的混溶性小于或等于7wt。 ％，以有效塑化聚合物并与其形成凝胶的量，触变剂和有益剂。 溶剂包括芳族醇，芳族酸的酯，芳族酮或其混合物。 组合物已经显着改善了剪切稀化行为和降低的注射力，使组合物通过注射容易地植入患者体表下方。
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公开(公告)号：US20120259318A1
公开(公告)日：2012-10-11
申请号：US13526375
申请日：2012-06-18
申请人： Catherine M. Rohloff , Guohua Chen , Andrew S. Luk , Rupal A. Ayer , Paul R. Houston , Michael A. Desjardin , Pauline Zamora , Stan Lam
发明人： Catherine M. Rohloff , Guohua Chen , Andrew S. Luk , Rupal A. Ayer , Paul R. Houston , Michael A. Desjardin , Pauline Zamora , Stan Lam
CPC分类号： A61K38/21 , A61K9/0004 , A61K9/0024 , A61K9/10 , A61K38/043 , A61K38/085 , A61K38/09 , A61K38/105 , A61K38/11 , A61K38/1808 , A61K38/185 , A61K38/191 , A61K38/2242 , A61K38/225 , A61K38/24 , A61K38/26 , A61K38/27 , A61K38/28 , A61K38/31 , A61K38/35 , A61K38/36 , A61K47/02 , A61K47/10 , A61K47/12 , A61K47/14 , A61K47/20 , A61K47/26 , A61K47/32 , Y10T29/494 , Y10T29/49826
摘要： A nonaqueous, single-phase vehicle that is capable of suspending an active agent. The nonaqueous, single-phase vehicle includes at least one solvent and at least one polymer and is formulated to exhibit phase separation upon contact with an aqueous environment. The at least one solvent may be selected from the group consisting of benzyl benzoate, decanol, ethyl hexyl lactate, and mixtures thereof and the at least one polymer may be selected from the group consisting of a polyester, pyrrolidone, ester of an unsaturated alcohol, ether of an unsaturated alcohol, polyoxyethylenepolyoxypropylene block copolymer, and mixtures thereof. In one embodiment, the at least one solvent is benzyl benzoate and the at least one polymer is polyvinylpyrrolidone. A stable, nonaqueous suspension formulation that includes the nonaqueous, single-phase vehicle and an active agent, and a method of forming the same, are also disclosed.
摘要翻译： 能够悬浮活性剂的非水性单相载体。 非水性单相载体包含至少一种溶剂和至少一种聚合物，并配制成在与水性环境接触时显示相分离。 所述至少一种溶剂可以选自苯甲酸苄酯，癸醇，乳酸乙基己酯及其混合物，并且所述至少一种聚合物可以选自聚酯，吡咯烷酮，不饱和醇的酯， 不饱和醇的醚，聚氧乙烯聚氧丙烯嵌段共聚物及其混合物。 在一个实施方案中，所述至少一种溶剂是苯甲酸苄酯，并且所述至少一种聚合物是聚乙烯吡咯烷酮。 还公开了包含非水单相载体和活性剂的稳定的非水悬浮液制剂及其形成方法。
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公开(公告)号：US08114437B2
公开(公告)日：2012-02-14
申请号：US11347562
申请日：2006-02-03
申请人： Catherine M. Rohloff , Guohua Chen , Andrew S. Luk , Rupal A. Ayer , Paul R. Houston , Michael A. Desjardin , Pauline Zamora , Stan Lam
发明人： Catherine M. Rohloff , Guohua Chen , Andrew S. Luk , Rupal A. Ayer , Paul R. Houston , Michael A. Desjardin , Pauline Zamora , Stan Lam
CPC分类号： A61K38/21 , A61K9/0004 , A61K9/0024 , A61K9/10 , A61K38/043 , A61K38/085 , A61K38/09 , A61K38/105 , A61K38/11 , A61K38/1808 , A61K38/185 , A61K38/191 , A61K38/2242 , A61K38/225 , A61K38/24 , A61K38/26 , A61K38/27 , A61K38/28 , A61K38/31 , A61K38/35 , A61K38/36 , A61K47/02 , A61K47/10 , A61K47/12 , A61K47/14 , A61K47/20 , A61K47/26 , A61K47/32 , Y10T29/494 , Y10T29/49826
摘要： A nonaqueous, single-phase vehicle that is capable of suspending an active agent. The nonaqueous, single-phase vehicle includes at least one solvent and at least one polymer and is formulated to exhibit phase separation upon contact with an aqueous environment. The at least one solvent may be selected from the group consisting of benzyl benzoate, decanol, ethyl hexyl lactate, and mixtures thereof and the at least one polymer may be selected from the group consisting of a polyester, pyrrolidone, ester of an unsaturated alcohol, ether of an unsaturated alcohol, polyoxyethylenepolyoxypropylene block copolymer, and mixtures thereof. In one embodiment, the at least one solvent is benzyl benzoate and the at least one polymer is polyvinylpyrrolidone. A stable, nonaqueous suspension formulation that includes the nonaqueous, single-phase vehicle and an active agent, and a method of forming the same, are also disclosed.
摘要翻译： 能够悬浮活性剂的非水性单相载体。 非水性单相载体包含至少一种溶剂和至少一种聚合物，并配制成在与水性环境接触时显示相分离。 所述至少一种溶剂可以选自苯甲酸苄酯，癸醇，乳酸乙基己酯及其混合物，并且所述至少一种聚合物可以选自聚酯，吡咯烷酮，不饱和醇的酯， 不饱和醇的醚，聚氧乙烯聚氧丙烯嵌段共聚物及其混合物。 在一个实施方案中，所述至少一种溶剂是苯甲酸苄酯，并且所述至少一种聚合物是聚乙烯吡咯烷酮。 还公开了包含非水单相载体和活性剂的稳定的非水悬浮液制剂及其形成方法。
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9.发明申请Osmotic drug delivery devices containing suspension formulations comprising particles having active agents and nonaqueous single-phase vehicles 有权渗透性药物递送装置含有包含具有活性剂和非水性单相载体的颗粒的悬浮液制剂公开(公告)号：US20110104111A1
公开(公告)日：2011-05-05
申请号：US12925864
申请日：2010-11-01
申请人： Catherine M. Rohloff , Guohua Chen , Andrew S. Luk , Rupal A. Ayer , Paul R. Houston , Michael A. Desjardin , Pauline Zamora , Stan Lam
发明人： Catherine M. Rohloff , Guohua Chen , Andrew S. Luk , Rupal A. Ayer , Paul R. Houston , Michael A. Desjardin , Pauline Zamora , Stan Lam
CPC分类号： A61K38/21 , A61K9/0004 , A61K9/0024 , A61K9/10 , A61K38/043 , A61K38/085 , A61K38/09 , A61K38/105 , A61K38/11 , A61K38/1808 , A61K38/185 , A61K38/191 , A61K38/2242 , A61K38/225 , A61K38/24 , A61K38/26 , A61K38/27 , A61K38/28 , A61K38/31 , A61K38/35 , A61K38/36 , A61K47/02 , A61K47/10 , A61K47/12 , A61K47/14 , A61K47/20 , A61K47/26 , A61K47/32 , Y10T29/494 , Y10T29/49826
摘要： A nonaqueous, single-phase vehicle that is capable of suspending an active agent. The nonaqueous, single-phase vehicle includes at least one solvent and at least one polymer and is formulated to exhibit phase separation upon contact with an aqueous environment. The at least one solvent may be selected from the group consisting of benzyl benzoate, decanol, ethyl hexyl lactate, and mixtures thereof and the at least one polymer may be selected from the group consisting of a polyester, pyrrolidone, ester of an unsaturated alcohol, ether of an unsaturated alcohol, polyoxyethylenepolyoxypropylene block copolymer, and mixtures thereof. In one embodiment, the at least one solvent is benzyl benzoate and the at least one polymer is polyvinylpyrrolidone. A stable, nonaqueous suspension formulation that includes the nonaqueous, single-phase vehicle and an active agent, and a method of forming the same, are also disclosed.
摘要翻译： 能够悬浮活性剂的非水性单相载体。 非水性单相载体包含至少一种溶剂和至少一种聚合物，并配制成在与水性环境接触时显示相分离。 所述至少一种溶剂可以选自苯甲酸苄酯，癸醇，乳酸乙基己酯及其混合物，并且所述至少一种聚合物可以选自聚酯，吡咯烷酮，不饱和醇的酯， 不饱和醇的醚，聚氧乙烯聚氧丙烯嵌段共聚物及其混合物。 在一个实施方案中，所述至少一种溶剂是苯甲酸苄酯，并且所述至少一种聚合物是聚乙烯吡咯烷酮。 还公开了包含非水单相载体和活性剂的稳定的非水悬浮液制剂及其形成方法。
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公开(公告)号：US07829109B2
公开(公告)日：2010-11-09
申请号：US10295603
申请日：2002-11-14
申请人： Guohua Chen , Paul R. Houston , Lothar Kleiner , John Spaltro
发明人： Guohua Chen , Paul R. Houston , Lothar Kleiner , John Spaltro
IPC分类号： A61F2/02
CPC分类号： A61K9/0024 , A61K47/10 , A61K47/14 , A61K47/34
摘要： Catheter injectable depot compositions are provided that include a bioerodible, biocompatible polymer, a solvent having miscibility in water of less than or equal to 7 wt. % at 25° C., in an amount effective to plasticize the polymer and form a gel therewith, a thixotropic agent, and a beneficial agent. The solvent comprises an aromatic alcohol, an ester of an aromatic acid, an aromatic ketone, or mixtures thereof. The compositions have substantially improved shear thinning behavior and reduced injection force, rendering the compositions readily implanted beneath a patient's body surface by injection.
摘要翻译： 提供导管可注射贮库组合物，其包括生物可腐蚀的生物相容性聚合物，在水中具有小于或等于7重量％的混溶性的溶剂。 ％，以有效塑化聚合物并与其形成凝胶的量，触变剂和有益剂。 溶剂包括芳族醇，芳族酸的酯，芳族酮或其混合物。 组合物具有显着改善的剪切稀化行为和降低的注射力，使组合物通过注射容易地植入患者体表下方。
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