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    Aryl-phenyl-sulfonamide-phenylene compounds and their use
    2.
    发明授权
    Aryl-phenyl-sulfonamide-phenylene compounds and their use 有权
    芳基 - 苯基 - 磺酰胺 - 亚苯基化合物及其用途

    公开(公告)号：US08207167B2

    公开(公告)日：2012-06-26

    申请号：US13063950

    申请日：2009-09-18

    申请人： Iain Robert Greig ,  Rose Mary Sheridan ,  Raymond Fisher ,  Matthew John Tozer ,  Juha Andrew Clase ,  Andrew Smith ,  Andrew Robert Tuffnell ,  Robert Jurgen Van 't Hof

    发明人： Iain Robert Greig ,  Rose Mary Sheridan ,  Raymond Fisher ,  Matthew John Tozer ,  Juha Andrew Clase ,  Andrew Smith ,  Andrew Robert Tuffnell ,  Robert Jurgen Van 't Hof

    IPC分类号： A61K31/5375 ,  A61K31/18 ,  C07D265/30 ,  C07C311/01

    CPC分类号： C07D303/36 ,  C07C311/21 ,  C07C311/39 ,  C07C2601/02 ,  C07D239/26 ,  C07D239/30 ,  C07D263/20 ,  C07D295/135

    摘要： The present invention pertains generally to the field of therapeutic compounds, and more specifically to certain aryl-phenyl-sulfonamido-phenylene compounds of the following formula (I) (collectively referred to herein as “APSAP compounds”). The present invention also pertains to pharmaceutical compositions comprising such compounds, and the use of such compounds and compositions, both in vitro and in vivo, in treatment, for example, of inflammation and/or joint destruction and/or bone loss; of disorders mediated by excessive and/or inappropriate and/or prolonged activation of the immune system; of inflammatory and autoimmune disorders, for example, rheumatoid arthritis, psoriasis, psoriatic arthritis, chronic obstructive pulmonary disease (COPD), atherosclerosis, inflammatory bowel disease, ankylosing spondylitis, and the like; of disorders associated with bone loss, such as bone loss associated with excessive osteoclast activity in rheumatoid arthritis, osteoporosis, cancer-associated bone disease, Paget's disease and the like, etc.; and of cancer, such as a haematological malignancy, a solid tumor, etc.

    摘要翻译： 本发明一般涉及治疗化合物领域，更具体地涉及下列通式（I）的某些芳基 - 苯基 - 亚磺酰氨基 - 亚苯基化合物（本文统称为“APSAP化合物”）。 本发明还涉及包含这些化合物的药物组合物，以及这些化合物和组合物在体外和体内在治疗例如炎症和/或关节破坏和/或骨丢失中的用途; 由免疫系统的过度和/或不适当和/或延长的激活介导的疾病; 炎性和自身免疫性疾病，例如类风湿性关节炎，牛皮癣，牛皮癣关节炎，慢性阻塞性肺病（COPD），动脉粥样硬化，炎性肠病，强直性脊柱炎等; 与骨丢失相关的疾病，例如与类风湿性关节炎中的过度破骨细胞活性相关的骨丢失，骨质疏松症，癌症相关的骨病，佩吉特氏病等; 和癌症，如血液恶性肿瘤，实体瘤等。

    Vehicle Locating Assembly
    7.
    发明申请
    Vehicle Locating Assembly 有权

    公开(公告)号：US20230117514A1

    公开(公告)日：2023-04-20

    申请号：US17501612

    申请日：2021-10-14

    申请人： Andrew Smith

    发明人： Andrew Smith

    IPC分类号： G06K7/10 ,  H01Q1/22 ,  G06K19/07

    摘要： A vehicle locating assembly for locating a suspect licensed vehicle includes a computer, a plurality of RFID tags, and a plurality of interrogators. A database is positioned on the computer and comprises a list of licensed vehicles, each of which is assigned a unique identifier. Each RFID tag is engaged to a respective license plate of a plurality of license plates, with the respective license plate being affixed to an associated licensed vehicle. The unique identifier of the associated licensed vehicle is written on the RFID tag. The interrogators are communicatively engaged to the computer and are mounted to create an array across a network of roads. The interrogator selectively powers the RFID tags so that they transmit their respective unique identifiers. The interrogator receives the respective unique identifiers and communicates them to the computer. The computer the isolates a unique identifier of a suspect licensed vehicle.

    System, method and computer program product for conditionally enabling an installation aspect
    9.
    发明授权
    System, method and computer program product for conditionally enabling an installation aspect 有权
    用于有条件地启用安装方面的系统，方法和计算机程序产品

    公开(公告)号：US09098365B2

    公开(公告)日：2015-08-04

    申请号：US12903381

    申请日：2010-10-13

    申请人： Andrew Smith ,  Craig Weissman ,  Danil Dvinov

    发明人： Andrew Smith ,  Craig Weissman ,  Danil Dvinov

    IPC分类号： G06F9/445 ,  G06F21/52

    CPC分类号： G06F8/61 ,  G06F21/52 ,  G06F2221/2141

    摘要： In accordance with embodiments, there are provided mechanisms and methods for conditionally enabling an installation aspect. In one embodiment, code to be installed within a multi-tenant on-demand database system is identified. Additionally, a feature required to install the code is identified, where the feature includes data that is required to be accessed by the code when the code is installed and run within the multi-tenant on-demand database system. Further, the feature is conditionally enabled, based on one or more criteria.

    摘要翻译： 根据实施例，提供了用于有条件地实现安装方面的机构和方法。 在一个实施例中，识别要安装在多租户按需数据库系统中的代码。 另外，确定了安装代码所需的功能，其中功能包括当代码在多租户按需数据库系统中安装并运行时需要由代码访问的数据。 此外，基于一个或多个标准有条件地启用该特征。