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公开(公告)号：US20100261179A1
公开(公告)日：2010-10-14
申请号：US12682123
申请日：2008-10-17
申请人： Jason Betley , Barry Boyes , John Walter Czajka , Michael Roy Fairs , Colin Fewster , Thomas David Ford , Douglas Jason Green , Piers Sebastian Harding , Gary Stephen Howard , Jay Lewington , William Richard Mawer , Catherine Mills , James Onslow , Carmelo Volpe
发明人： Jason Betley , Barry Boyes , John Walter Czajka , Michael Roy Fairs , Colin Fewster , Thomas David Ford , Douglas Jason Green , Piers Sebastian Harding , Gary Stephen Howard , Jay Lewington , William Richard Mawer , Catherine Mills , James Onslow , Carmelo Volpe
CPC分类号： B03C1/288 , B03C2201/18 , B03C2201/26 , G01N35/0098 , G01N2035/00366
摘要： The application provides sample preparation devices and analyses. The devices and analyzes allow for the rapid preparation and analysis of samples using a variety of techniques, including PCR, by even unskilled users.
摘要翻译： 该应用程序提供样品制备装置和分析。 这些设备和分析允许甚至不熟练的用户使用各种技术（包括PCR）快速准备和分析样品。
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公开(公告)号：US20100192706A1
公开(公告)日：2010-08-05
申请号：US12449855
申请日：2008-02-28
申请人： Michael Roy Fairs , Thomas David Ford , Piers Sebastian Harding , Gary Stephen Howard , Barry Boyes , John Walter Czajka , Douglas Jason Green , Jay Lewington , Carmelo Volpe , Colin Fewster , Jason Betley , Catherine Mills , William Richard Mawer
发明人： Michael Roy Fairs , Thomas David Ford , Piers Sebastian Harding , Gary Stephen Howard , Barry Boyes , John Walter Czajka , Douglas Jason Green , Jay Lewington , Carmelo Volpe , Colin Fewster , Jason Betley , Catherine Mills , William Richard Mawer
IPC分类号： G01N1/10
CPC分类号： G01N1/28 , B01L3/502 , B01L3/5082 , B01L2300/046 , B01L2300/0681 , B01L2300/087 , B01L2400/0683 , G01N2035/1086
摘要： Apparatus for preparing a biological sample for PCR analysis has an inlet (4) for receiving the sample (15) and a sieve (13) through which the sample is forced by screwing down an inlet cap (16). A lysis solution between two rupturable seals (11 and 12) is effective to disrupt the cells of the sample and release nucleic acid. The apparatus is mounted releasably on a PCR machine (2) having a motor (2′) releasably coupled with a drive mechanism (3, 36,40) in the apparatus to effect a rotary and a vertical up and down movement of its components (30, 31, 32, 42). The apparatus has a transparent cuvette (5) and a needle (71) extending to the lower end of the cuvette, by which the prepared sample is dispensed to the cuvette for PCR analysis.
摘要翻译： 用于制备用于PCR分析的生物样品的装置具有用于接收样品（15）的入口（4）和通过拧入入口盖（16）来迫使样品被迫的筛子。 两个可破裂的密封件（11和12）之间的裂解溶液有效地破坏样品的细胞并释放核酸。 该装置可释放地安装在具有可释放地与设备中的驱动机构（3,36,40）联接的马达（2'）的PCR机（2）上，以实现其部件的旋转和垂直上下运动 30，31，32，42）。 该装置具有透明比色皿（5）和延伸到比色皿下端的针（71），通过该针将准备的样品分配到比色皿进行PCR分析。
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公开(公告)号：US08327724B2
公开(公告)日：2012-12-11
申请号：US12449855
申请日：2008-02-28
申请人： Michael Roy Fairs , Thomas David Ford , Piers Sebastian Harding , Gary Stephen Howard , Barry Boyes , John Walter Czajka , Douglas Jason Green , Jay Lewington , Carmelo Volpe , Colin Fewster , Jason Betley , Catherine Mills , William Richard Mawer
发明人： Michael Roy Fairs , Thomas David Ford , Piers Sebastian Harding , Gary Stephen Howard , Barry Boyes , John Walter Czajka , Douglas Jason Green , Jay Lewington , Carmelo Volpe , Colin Fewster , Jason Betley , Catherine Mills , William Richard Mawer
IPC分类号： G01N1/00
CPC分类号： G01N1/28 , B01L3/502 , B01L3/5082 , B01L2300/046 , B01L2300/0681 , B01L2300/087 , B01L2400/0683 , G01N2035/1086
摘要： Apparatus for preparing a biological sample for PCR analysis has an inlet (4) for receiving the sample (15) and a sieve (13) through which the sample is forced by screwing down an inlet cap (16). A lysis solution between two rupturable seals (11 and 12) is effective to disrupt the cells of the sample and release nucleic acid. The apparatus is mounted releasably on a PCR machine (2) having a motor (2′) releasably coupled with a drive mechanism (3, 36,40) in the apparatus to effect a rotary and a vertical up and down movement of its components (30, 31, 32, 42). The apparatus has a transparent cuvette (5) and a needle (71) extending to the lower end of the cuvette, by which the prepared sample is dispensed to the cuvette for PCR analysis.
摘要翻译： 用于制备用于PCR分析的生物样品的装置具有用于接收样品（15）的入口（4）和通过拧入入口盖（16）来迫使样品被迫的筛子。 两个可破裂的密封件（11和12）之间的裂解溶液有效地破坏样品的细胞并释放核酸。 该装置可释放地安装在具有可释放地与设备中的驱动机构（3,36,40）联接的马达（2'）的PCR机（2）上，以实现其部件的旋转和垂直上下运动 30，31，32，42）。 该装置具有透明比色皿（5）和延伸到比色皿下端的针（71），通过该针将准备的样品分配到比色皿进行PCR分析。
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公开(公告)号：US20090066507A1
公开(公告)日：2009-03-12
申请号：US12216312
申请日：2008-07-02
IPC分类号： G08B21/00
CPC分类号： B01L7/52 , B01L2200/14 , B01L2200/147 , B01L2200/185 , B01L2300/023 , B01L2300/024 , G01N35/00871
摘要： A method and apparatus for providing assay information to a portable detection unit, by way of a remote server in communication with the portable detection unit or a consumable with stored information for use with the portable detection unit. Global Positioning System (GPS) information is provided to a portable detection unit having a GPS receiver, so that the unit can determine its current position, including altitude. Based on the determined position, assays and parameters, such as PCR melt temperatures, can be selected. Assays to be performed by the portable detection unit can be selected based on the results of a prior assay.
摘要翻译： 一种用于通过与便携式检测单元通信的远程服务器或具有用于便携式检测单元的存储信息的消费品向便携式检测单元提供测定信息的方法和装置。 全球定位系统（GPS）信息被提供给具有GPS接收器的便携式检测单元，使得该单元可以确定其当前位置，包括高度。 基于确定的位置，可以选择测定和参数，例如PCR熔融温度。 可以基于先前测定的结果来选择由便携式检测单元执行的测定。
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公开(公告)号：US08138909B2
公开(公告)日：2012-03-20
申请号：US12216312
申请日：2008-07-02
IPC分类号： G08B29/00
CPC分类号： B01L7/52 , B01L2200/14 , B01L2200/147 , B01L2200/185 , B01L2300/023 , B01L2300/024 , G01N35/00871
摘要： A method and apparatus for providing assay information to a portable detection unit, by way of a remote server in communication with the portable detection unit or a consumable with stored information for use with the portable detection unit. Global Positioning System (GPS) information is provided to a portable detection unit having a GPS receiver, so that the unit can determine its current position, including altitude. Based on the determined position, assays and parameters, such as PCR melt temperatures, can be selected. Assays to be performed by the portable detection unit can be selected based on the results of a prior assay.
摘要翻译： 一种用于通过与便携式检测单元通信的远程服务器或具有用于便携式检测单元的存储信息的消费品向便携式检测单元提供测定信息的方法和装置。 全球定位系统（GPS）信息被提供给具有GPS接收器的便携式检测单元，使得该单元可以确定其当前位置，包括高度。 基于确定的位置，可以选择测定和参数，例如PCR熔融温度。 可以基于先前测定的结果来选择由便携式检测单元执行的测定。
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公开(公告)号：US07170594B2
公开(公告)日：2007-01-30
申请号：US10837745
申请日：2004-05-04
申请人： Douglas Jason Green
发明人： Douglas Jason Green
IPC分类号： G01N1/10
CPC分类号： B01L3/50851 , B01L7/52 , B01L2300/0654 , B01L2300/1827 , B01L2300/1844 , G01N2015/0088 , G01N2035/00356
摘要： A detection device includes a housing containing a chamber configured to receive a specimen, a heating element disposed in the chamber, and an optical window to permit observation of the chamber. The housing includes a passage configured to allow fluid flow through the chamber to thereby provide cooling.
摘要翻译： 一种检测装置，包括：壳体，其容纳配置成接收试样的腔室，设置在腔室中的加热元件，以及允许观察腔室的光学窗口。 壳体包括通道，其构造成允许流体流过腔室从而提供冷却。
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公开(公告)号：US08110397B2
公开(公告)日：2012-02-07
申请号：US12172144
申请日：2008-07-11
申请人： Douglas Jason Green
发明人： Douglas Jason Green
CPC分类号： G01N1/28 , B01F15/0205 , B01F15/0212 , B01F15/0223 , B01L3/502 , B01L2200/0647 , B01L2200/16 , B01L2400/0683 , G01N1/02 , G01N2001/007 , G01N2001/027 , G01N2001/028 , Y02P20/582
摘要： A reconfigurable sample preparation device includes a rotary plunger device having a hollow body and a coupling device, provided above one end of the rotary plunger, and accommodating a sample. The device also includes at least one sealed reagent module. When the rotary plunger is rotated on the coupling device, a film of the reagent module is pierced, mixing the sample with a substance from the reagent module.
摘要翻译： 可重构样品制备装置包括具有中空体的旋转柱塞装置和设置在旋转柱塞的一端上方并且容纳样品的联接装置。 该装置还包括至少一个密封的试剂模块。 当旋转柱塞在耦合装置上旋转时，刺穿试剂模块的膜，将样品与来自试剂模块的物质混合。
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公开(公告)号：US20090079975A1
公开(公告)日：2009-03-26
申请号：US12172142
申请日：2008-07-11
申请人： Douglas Jason Green , Jordan Fields
发明人： Douglas Jason Green , Jordan Fields
IPC分类号： G01N21/01
CPC分类号： G02B6/4201 , G01N21/645 , G01N2021/6484 , G02B6/424 , G02B6/4246 , G02B6/4257 , G02B6/4261 , G02B6/4268 , G02B6/4269 , G02B6/4286 , G02B6/4292
摘要： A sealed and decontaminated fiber optic detection apparatus includes an optics portion with individual chambers. Each chamber housing optical and electro-optical components. A manifold accommodates fibers, with each of the fibers being in optical communication with the optical and electro-optical components of a corresponding chamber. The apparatus also includes a sample holder that holds a sample to be tested and a mounting device provided between the sample holder and the manifold. The mounting device and the manifold form a sealed fiber optic interface between the sample holder and the optics portion.
摘要翻译： 密封和净化的光纤检测装置包括具有各个室的光学部分。 每个腔室都容纳光学和电光元件。 歧管容纳纤维，其中每个纤维与相应室的光学和电光学部件光学连通。 该装置还包括保持待测试样品的样品架和设置在样品保持器和歧管之间的安装装置。 安装装置和歧管在样品保持器和光学部件之间形成密封的光纤接口。
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公开(公告)号：US20090075344A1
公开(公告)日：2009-03-19
申请号：US12172144
申请日：2008-07-11
申请人： Douglas Jason Green
发明人： Douglas Jason Green
CPC分类号： G01N1/28 , B01F15/0205 , B01F15/0212 , B01F15/0223 , B01L3/502 , B01L2200/0647 , B01L2200/16 , B01L2400/0683 , G01N1/02 , G01N2001/007 , G01N2001/027 , G01N2001/028 , Y02P20/582
摘要： A reconfigurable sample preparation device includes a rotary plunger device having a hollow body and a coupling device, provided above one end of the rotary plunger, and accommodating a sample. The device also includes at least one sealed reagent module. When the rotary plunger is rotated on the coupling device, a film of the reagent module is pierced, mixing the sample with a substance from the reagent module.
摘要翻译： 可重构样品制备装置包括具有中空体的旋转柱塞装置和设置在旋转柱塞的一端上方并且容纳样品的联接装置。 该装置还包括至少一个密封的试剂模块。 当旋转柱塞在耦合装置上旋转时，刺穿试剂模块的膜，将样品与来自试剂模块的物质混合。
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公开(公告)号：US07933011B2
公开(公告)日：2011-04-26
申请号：US12172142
申请日：2008-07-11
申请人： Douglas Jason Green , Jordan Fields
发明人： Douglas Jason Green , Jordan Fields
IPC分类号： G01N21/01
CPC分类号： G02B6/4201 , G01N21/645 , G01N2021/6484 , G02B6/424 , G02B6/4246 , G02B6/4257 , G02B6/4261 , G02B6/4268 , G02B6/4269 , G02B6/4286 , G02B6/4292
摘要： A sealed and decontaminated fiber optic detection apparatus includes an optics portion with individual chambers. Each chamber housing optical and electro-optical components. A manifold accommodates fibers, with each of the fibers being in optical communication with the optical and electro-optical components of a corresponding chamber. The apparatus also includes a sample holder that holds a sample to be tested and a mounting device provided between the sample holder and the manifold. The mounting device and the manifold form a sealed fiber optic interface between the sample holder and the optics portion.
摘要翻译： 密封和净化的光纤检测装置包括具有各个室的光学部分。 每个腔室都容纳光学和电光元件。 歧管容纳纤维，其中每个纤维与相应室的光学和电光学部件光学连通。 该装置还包括保持待测试样品的样品架和设置在样品保持器和歧管之间的安装装置。 安装装置和歧管在样品保持器和光学部件之间形成密封的光纤接口。
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