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    Multiplex detection of respiratory pathogens
    3.
    发明授权
    Multiplex detection of respiratory pathogens 有权
    多重检测呼吸道病原体

    公开(公告)号：US08232058B2

    公开(公告)日：2012-07-31

    申请号：US12161291

    申请日：2007-01-22

    申请人： Mary McBride ,  Thomas Slezak ,  James M. Birch

    发明人： Mary McBride ,  Thomas Slezak ,  James M. Birch

    IPC分类号： C12Q1/68 ,  C12P19/34 ,  C07H21/04

    CPC分类号： C12Q1/701 ,  C12Q2531/113

    摘要： Described are kits and methods useful for detection of respiratory pathogens (influenza A (including subtyping capability for H1, H3, H5 and H7 subtypes) influenza B, parainfluenza (type 2), respiratory syncytial virus, and adenovirus) in a sample. Genomic sequence information from the respiratory pathogens was analyzed to identify signature sequences, e.g., polynucleotide sequences useful for confirming the presence or absence of a pathogen in a sample. Primer and probe sets were designed and optimized for use in a PCR based, multiplexed Luminex assay to successfully identify the presence or absence of pathogens in a sample.

    摘要翻译： 描述了用于检测样品中呼吸道病原体（甲型流感（包括H1，H3，H5和H7亚型的亚型能力）乙型流感，副流感（2型），呼吸道合胞病毒和腺病毒）的试剂盒和方法。 分析来自呼吸道病原体的基因组序列信息以鉴定特征序列，例如可用于确认样品中病原体存在或不存在的多核苷酸序列。 引物和探针组被设计和优化用于基于PCR的多重Luminex测定，以成功鉴定样品中病原体的存在或不存在。

    ASK/RESPOND AFFINITY GROUP REFERRAL METHOD AND APPARATUS
    4.
    发明申请
    ASK/RESPOND AFFINITY GROUP REFERRAL METHOD AND APPARATUS 审中-公开
    ASK / RESPOND AFFINITY GROUP REFERRAL METHOD AND APPARATUS

    公开(公告)号：US20100114702A1

    公开(公告)日：2010-05-06

    申请号：US12611059

    申请日：2009-11-02

    申请人： Arthur WU ,  Justin Lin ,  Kenneth Miller ,  Mary McBride ,  Julie D'Agostino ,  Aaron Cohen ,  Derek Greenberg ,  Steven Ketchpel ,  Sarah Diego ,  Todd Werth

    发明人： Arthur WU ,  Justin Lin ,  Kenneth Miller ,  Mary McBride ,  Julie D'Agostino ,  Aaron Cohen ,  Derek Greenberg ,  Steven Ketchpel ,  Sarah Diego ,  Todd Werth

    IPC分类号： G06Q99/00 ,  G06Q30/00 ,  G06Q50/00 ,  G06F3/048 ,  G06F15/16

    CPC分类号： G06Q30/08 ,  G06Q30/0255 ,  G06Q50/01

    摘要： An ask/respond affinity group referral method and apparatus comprises a community of individuals having an implied social contract, where the individuals are affiliated with each other to provide assistance and help to each other. In such community, the individuals do not know each other, but are joined together to help each other around a common interest. In such community, any individual may ask everybody else a question and the others can each respond. The community is specifically directed to mothers in every phase of their relationship, i.e. grandmothers, single mothers, mothers with husbands in Iraq, mothers with children, mothers without children, et cetera and is, therefore, directed to all kinds of phases and special needs of mothers. An interactive timeline tool serves to record information about their children, to anticipate future child development needs, and to collaborate with other members of the ask/respond affinity group having similar parenting experiences.

    摘要翻译： 询问/回复亲和团体转介方法和装置包括具有隐含的社会契约的个人社区，个人相互关联以提供彼此的帮助和帮助。 在这样的社区，个人不认识对方，而是结合在一起，以协助彼此的共同兴趣。 在这样的社区，任何人都可以问别人一个问题，而其他人都可以回答。 社区在每一阶段的关系中都是专门针对母亲，即祖母，单身母亲，在伊拉克的丈夫的母亲，有子女的母亲，没有子女的母亲等等，因此针对的是各种阶段和特殊需要 的母亲。 交互式时间表工具用于记录关于子女的信息，预测未来的儿童发展需求，并与具有类似育儿经验的询问/回应亲和组的其他成员进行合作。

    MULTIPLEX DETECTION OF RESPIRATORY PATHOGENS
    5.
    发明申请
    MULTIPLEX DETECTION OF RESPIRATORY PATHOGENS 有权
    呼吸道病原体多重检测

    公开(公告)号：US20090305229A1

    公开(公告)日：2009-12-10

    申请号：US12161291

    申请日：2007-01-22

    申请人： Mary McBride ,  Thomas Slezak ,  James M. Birch

    发明人： Mary McBride ,  Thomas Slezak ,  James M. Birch

    IPC分类号： C12Q1/70

    CPC分类号： C12Q1/701 ,  C12Q2531/113

    摘要： Described are kits and methods useful for detection of respiratory pathogens (influenza A (including subtyping capability for H1, H3, H5 and H7 subtypes) influenza B, parainfluenza (type 2), respiratory syncytial virus, and adenovirus) in a sample. Genomic sequence information from the respiratory pathogens was analyzed to identify signature sequences, e.g., polynucleotide sequences useful for confirming the presence or absence of a pathogen in a sample. Primer and probe sets were designed and optimized for use in a PCR based, multiplexed Luminex assay to successfully identify the presence or absence of pathogens in a sample.

    摘要翻译： 描述了用于检测样品中呼吸道病原体（甲型流感（包括H1，H3，H5和H7亚型的亚型能力）乙型流感，副流感（2型），呼吸道合胞病毒和腺病毒）的试剂盒和方法。 分析来自呼吸道病原体的基因组序列信息以鉴定特征序列，例如可用于确认样品中病原体存在或不存在的多核苷酸序列。 引物和探针组被设计和优化用于基于PCR的多重Luminex测定，以成功鉴定样品中病原体的存在或不存在。