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公开(公告)号：US08709398B2
公开(公告)日：2014-04-29
申请号：US12450451
申请日：2008-03-28
申请人： John MacSharry , Liam O'Mahony , David O'Sullivan , Barry Kiely
发明人： John MacSharry , Liam O'Mahony , David O'Sullivan , Barry Kiely
CPC分类号： A61K35/745 , A23L33/135 , A23V2002/00 , C12R1/01 , Y02A50/473
摘要： Probiotic Bifidobacterium strain AH1205 or mutants or variants thereof are immunomodulatory following oral consumption and are useful in the prophylaxis and/or treatment of inflammatory activity such as undesirable gastrointestinal inflammatory activity for example inflammatory bowel disease.
摘要翻译： 益生菌双歧杆菌菌株AH1205或其突变体或变体在口服消耗后是免疫调节的，并且可用于预防和/或治疗炎症活动，例如不期望的胃肠炎症活动，例如炎症性肠病。
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公开(公告)号：US20110020284A1
公开(公告)日：2011-01-27
申请号：US12450427
申请日：2008-03-28
申请人： John MacSharry , Liam O'Mahony , David O'Sullivan , Barry Kiely
发明人： John MacSharry , Liam O'Mahony , David O'Sullivan , Barry Kiely
IPC分类号： A61K35/74 , C12N1/21 , C12N1/20 , A61P29/00 , A61P11/06 , A61P37/04 , A61P35/00 , A61P1/12 , A61P25/00 , A61P37/02 , A61P25/28 , A61P19/02 , A61P3/10 , A61P31/04 , A61P31/12 , A61P31/10 , A61P31/18 , A61P35/04 , A61P3/00 , A61P1/04 , A61P37/08 , A61P7/00 , A61P13/12 , A61P9/10 , A61P11/00 , A61P1/16 , A61P19/10 , A61P17/06 , A61P17/10 , A61K39/02
CPC分类号： C12R1/01 , A23L33/135 , A61K35/745 , C12N1/20 , Y02A50/47 , Y02A50/473 , Y02A50/481
摘要： Bifidobacterium strain AH1206 or mutants or variants thereof are immunomodulatory following oral consumption and are useful in the prophylaxis and/or treatment of inflammatory activity for example undesirable gastrointestinal inflammatory activity such as inflammatory bowel disease.
摘要翻译： 双歧杆菌菌株AH1206或其突变体或变体在口服消耗后是免疫调节的，并且可用于预防和/或治疗炎症活性，例如不期望的胃肠炎症活动，例如炎性肠病。
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公开(公告)号：US20120207713A1
公开(公告)日：2012-08-16
申请号：US13347289
申请日：2012-01-10
申请人： John MacSharry , Liam O'Mahony , David O'Sullivan , Barry Kiely
发明人： John MacSharry , Liam O'Mahony , David O'Sullivan , Barry Kiely
IPC分类号： A61K35/74 , A61P1/04 , A61P35/00 , A61P37/00 , A61P19/02 , A61P29/00 , A61P1/12 , A61P25/28 , A61P3/10 , A61P31/18 , A61P25/00 , A61P31/04 , A61P31/12 , A61P31/10 , A61P37/06 , A61P11/06 , A61P3/04 , A61P27/14 , A61P35/04 , A61P9/00 , A61P13/12 , A61P1/16 , A61P7/06 , A61P3/02 , A61P19/10 , A61P5/00 , A61P17/02 , A61P17/00 , A61P17/06 , A61P17/10 , A61P37/04 , C12N1/20 , A61P1/02 , A61P13/00 , A61P15/00 , A61P1/00
CPC分类号： A61K35/745 , C12N1/20 , C12R1/01 , Y02A50/473
摘要： Bifidobacterium strain AH1206 or mutants or variants thereof are immunomodulatory following oral consumption and are useful in the prophylaxis and/or treatment of inflammatory activity for example undesirable gastrointestinal inflammatory activity such as inflammatory bowel disease.
摘要翻译： 双歧杆菌菌株AH1206或其突变体或变体在口服消耗后是免疫调节的，并且可用于预防和/或治疗炎症活性，例如不期望的胃肠炎症活动，例如炎性肠病。
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公开(公告)号：US08557233B2
公开(公告)日：2013-10-15
申请号：US12450427
申请日：2008-03-28
申请人： John MacSharry , Liam O'Mahony , David O'Sullivan , Barry Kiely
发明人： John MacSharry , Liam O'Mahony , David O'Sullivan , Barry Kiely
IPC分类号： A61K35/74 , A61K39/02 , C12N1/21 , C12N1/20 , A61P29/00 , A61P11/06 , A61P37/04 , A61P35/00 , A61P1/12 , A61P25/00 , A61P37/02
CPC分类号： C12R1/01 , A23L33/135 , A61K35/745 , C12N1/20 , Y02A50/47 , Y02A50/473 , Y02A50/481
摘要： Bifidobacterium strain AH1206 or mutants or variants thereof are immunomodulatory following oral consumption and are useful in the prophylaxis and/or treatment of inflammatory activity for example undesirable gastrointestinal inflammatory activity such as inflammatory bowel disease.
摘要翻译： 双歧杆菌菌株AH1206或其突变体或变体在口服消耗后是免疫调节的，并且可用于预防和/或治疗炎症活性，例如不期望的胃肠炎症活动，例如炎性肠病。
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公开(公告)号：US20110020400A1
公开(公告)日：2011-01-27
申请号：US12450451
申请日：2008-03-28
申请人： John MacSharry , Liam O'Mahony , David O'Sullivan , Barry Kiely
发明人： John MacSharry , Liam O'Mahony , David O'Sullivan , Barry Kiely
IPC分类号： A61K39/02 , C12N1/20 , C12N1/21 , A61P29/00 , A61P35/00 , A61P37/02 , A61P37/04 , A61P19/02 , A61P1/12 , A61P25/00 , A61P25/28 , A61P37/08 , A61P17/10 , A61P17/06 , A61P19/10 , A61P9/10 , A61P7/00 , A61P1/04 , A61P3/04 , A61P11/00 , A61P3/10 , A61P31/12 , A61P31/04 , A61P31/10 , A61P31/18 , A61P35/04 , A61P7/06 , A61P1/16 , A61P43/00
CPC分类号： A61K35/745 , A23L33/135 , A23V2002/00 , C12R1/01 , Y02A50/473
摘要： Probiotic Bifidobacterium strain AH1205 or mutants or variants thereof are immunomodulatory following oral consumption and are useful in the prophylaxis and/or treatment of inflammatory activity such as undesirable gastrointestinal inflammatory activity for example inflammatory bowel disease.
摘要翻译： 益生菌双歧杆菌菌株AH1205或其突变体或变体在口服消耗后是免疫调节的，并且可用于预防和/或治疗炎症活动，例如不期望的胃肠炎症活动，例如炎症性肠病。
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公开(公告)号：US20060269534A1
公开(公告)日：2006-11-30
申请号：US11443765
申请日：2006-05-31
申请人： Thomas Boileau , Barry Kiley , Liam O'Mahony , John MacSharry , Greg Sunvold
发明人： Thomas Boileau , Barry Kiley , Liam O'Mahony , John MacSharry , Greg Sunvold
CPC分类号： C12R1/01 , A23C9/1234 , A23C19/0323 , A23K10/18 , A23K50/40 , A23K50/42 , A23K50/48 , A61K35/745 , C12N1/20 , Y10S435/822
摘要： According to the invention there is provided a strain of lactic acid bacteria of the genus Bifidobacteria obtainable by isolation from resected and washed feline gastrointestinal tract having a probiotic activity in animals. Methods of use and compositions comprising the Bifidobacteria of the present invention are also provided.
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公开(公告)号：US20060270020A1
公开(公告)日：2006-11-30
申请号：US11443974
申请日：2006-05-31
申请人： Thomas Boileau , Barry Kiley , Liam O'Mahony , John MacSharry , Gregory Sunvold
发明人： Thomas Boileau , Barry Kiley , Liam O'Mahony , John MacSharry , Gregory Sunvold
IPC分类号： C12N1/20
摘要： According to the invention there is provided a strain of lactic acid bacteria of the genus Lactobacilli obtainable by isolation from resected and washed feline gastrointestinal tract having a probiotic activity in animals. Methods of use and compositions comprising the Lactobacilli of the present invention are also provided.
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公开(公告)号：US20060121015A1
公开(公告)日：2006-06-08
申请号：US11149195
申请日：2005-06-10
申请人： John Collins , Gerald O'Sullivan , Liam O'Mahony , Fergus Shanahan , Barry Kiely
发明人： John Collins , Gerald O'Sullivan , Liam O'Mahony , Fergus Shanahan , Barry Kiely
CPC分类号： C12N1/20 , A23L33/135 , A23Y2300/00 , A23Y2300/55 , A61K35/745 , C12R1/02
摘要： A Bifidobacterium strain, AH208, AH209, AH210, AH211, AH212 or AH214 or mutants or variants thereof are useful in the prophylaxis and/or treatment of inflammatory activity especially undesirable gastrointestinal inflammatory activity, such as inflammatory bowel disease or irritable bowel syndrome.
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公开(公告)号：US20050158294A1
公开(公告)日：2005-07-21
申请号：US11013117
申请日：2004-12-15
申请人： Thomas Boileau , Michael Ceddia , John Collins , Gary Davenport , Barry Kiely , Liam O'Mahony , Gregory Sunvold , Mark Tetrick , Robert Vickers
发明人： Thomas Boileau , Michael Ceddia , John Collins , Gary Davenport , Barry Kiely , Liam O'Mahony , Gregory Sunvold , Mark Tetrick , Robert Vickers
IPC分类号： A61K35/745 , A61K45/00 , C12N1/20
CPC分类号： C12N1/20 , A23K10/18 , A23K50/40 , A61K35/745 , C12R1/01
摘要： According to the invention there is provided a strain of lactic acid bacteria of the species Bifidobacteria pseudolongum obtainable by isolation from resected and washed canine gastrointestinal tract having a probiotic activity in animals. Methods of use and compositions comprising the Bifidobacteria pseudolongum of the present invention are also provided.
摘要翻译： 根据本发明，提供了通过从动物中具有益生菌活性的切除和洗涤的犬胃肠道分离而获得的物种双歧杆菌假单胞菌的乳酸菌菌株。 还提供了使用本发明的双歧杆菌双歧杆菌的使用方法和组合物。
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公开(公告)号：US10144978B2
公开(公告)日：2018-12-04
申请号：US13468374
申请日：2012-05-10
IPC分类号： A61K39/02 , A61P1/00 , A61P1/04 , C12R1/01 , A23C9/123 , A23G9/36 , A61K35/745 , C12N1/20 , A23L33/135
摘要： Probiotic Bifidobacterium strain AH1714 is significantly immunomodulatory following oral consumption. The strain is useful as an immunomodulatory biotherapeutic agent.
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