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公开(公告)号：US12257586B2
公开(公告)日：2025-03-25
申请号：US17055167
申请日：2019-05-14
Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY
Inventor： Sang Kyung Kim , Bong Kyun Kim , Jung Min Kim , Seungwon Jung
Abstract: The present invention relates to a porous particle composite for PCR, wherein the porous particle composite distributes photothermal nano-elements that generate heat by absorbing light in porous particles in which nucleic acid amplification occurs through temperature control so as not to adjust the temperature of the entire sample by using a hot plate or the like but to adjust the temperature inside the particles by irradiating light to the porous particles to allow nucleic acid amplification inside thereof, thereby reducing energy consumption and shortening diagnostic time.
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2.发明授权公开(公告)号：US10519490B2
公开(公告)日：2019-12-31
申请号：US15499005
申请日：2017-04-27
Applicant: Korea Institute of Science and Technology
Inventor： Sang Kyung Kim , Seungwon Jung
IPC: C12Q1/68 , C12Q1/6853 , C12Q1/686
Abstract: A porous matrix according to the present disclosure, wherein a nucleic acid primer-carbon material composite in which one or more nucleic acid primer of a forward primer and a reverse primer as a polymerase chain reaction (PCR) primer is bound to a carbon material is included in the pores of the matrix, provides improved amplification efficiency as compared to a matrix wherein the nucleic acid primer is present on the outer surface of the matrix or a porous matrix wherein the nucleic acid primer is directly fixed inside pores. The porous matrix of the present disclosure can effectively detect various kinds of target nucleic acids simultaneously and analyze them in real time by varying the kinds of the nucleic acid primers included in the matrix. Therefore, it is useful in amplifying multiple nucleic acids.
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Patent Agency Ranking
公开(公告)号：US10648024B2
公开(公告)日：2020-05-12
申请号：US15032541
申请日：2014-10-28
Applicant: Korea Institute of Science and Technology
Inventor： Sang Kyung Kim , Nakwon Choi , Dong Jin Lee , Seungwon Jung
Abstract: A porous structure according to the present invention has a polymerase chain reaction (PCT) primer inside pores thereof, and hence, even an inner portion thereof can be used unlike general structures of which only surfaces are used for amplification and detection, thereby maximizing reactivity. In addition, the differentiating of the kinds of primers contained in respective structures leads to detection of several kinds of target nucleic acids at the same and real-time analysis thereof at the same time, and thus is useful for multiplex real-time PCR.
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公开(公告)号：US10017537B2
公开(公告)日：2018-07-10
申请号：US14793032
申请日：2015-07-07
Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY
Inventor： Hyunjung Yi , Ki Young Lee , Chaun Jang , Joonyeon Chang , Sang Kyung Kim , Soomi Ju
IPC: C07K7/06
CPC classification number: C07K7/06
Abstract: Provided is a peptide including X2SX1AAX2X3P (SEQ ID NO. 1), X2X2PX3X2AX3P (SEQ ID NO. 2), SX1AAX2X3P (SEQ ID NO. 3), or X2PX3X2AX3P (SEQ ID NO. 4), which bind to graphitic materials or volatile organic compounds.
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公开(公告)号：US10739301B2
公开(公告)日：2020-08-11
申请号：US15684939
申请日：2017-08-24
Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY
Inventor： Kwan Hyi Lee , Minhong Jeun , Seok Lee , Sang Kyung Kim , Sungwook Park
IPC: H01L29/45 , G01N27/414
Abstract: Provided is a field-effect transistor that can reduce noise, be produced by a simplified manufacturing method, and also have a plurality of active patterns and gate patterns designed to be combinable according to a detection purpose. The field-effect transistor includes a lower silicon layer and a buried oxide layer disposed on the lower silicon layer; an active pattern disposed on the buried oxide layer and including a channel region, a source region, and a drain region; a gate pattern disposed on the active pattern to at least partially overlap the active pattern; a source electrode disposed in direct contact with the source region on the active pattern, and a drain electrode disposed in direct contact with the drain region on the active pattern; and a gate insulating film disposed between the active pattern and the gate pattern.
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公开(公告)号：US10690582B2
公开(公告)日：2020-06-23
申请号：US15698646
申请日：2017-09-08
Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY
Inventor： Jaebin Choi , Chulki Kim , Sang Kyung Kim , Seok Lee , Chaehyun Lim , Jae Hun Kim , Taikjin Lee , Minah Seo
Abstract: An apparatus for sensing biomolecules includes: a storage in which a solution containing a target material is received; a sensor configured to sense the target material; and a flow controller connected between the storage and the sensor to supply the solution to the sensor, wherein the flow controller controls a solution flow to supply the solution containing the target material and the solution containing no target material in an alternating manner. According to the apparatus for sensing biomolecules, the sensing device always achieves a sensing offset, and consequently, long-term continuous measurement is enabled, leading to the maximized usage efficiency of the sensor, and the value of quantitative measurement can be obtained with high precision.
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公开(公告)号：US09568456B2
公开(公告)日：2017-02-14
申请号：US14737648
申请日：2015-06-12
Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY
Inventor： Hyunjung Yi , Sang Kyung Kim , Soomi Ju , Ki Young Lee
IPC: C07K7/06 , G01N33/00 , G01N29/02 , G01N29/036 , C07K14/005
CPC classification number: G01N33/0004 , C07K7/06 , C07K14/005 , C12N2795/14122 , G01N29/022 , G01N29/036 , G01N2291/0256
Abstract: Provided is a peptide selectively binding to a volatile organic compound, in which the peptide has excellent selectivity for the volatile organic compound and has stability at room temperature so as to effectively collect and detect or eliminate the volatile organic compound.
Abstract translation: 提供了选择性结合挥发性有机化合物的肽，其中肽对挥发性有机化合物具有优异的选择性，并且在室温下具有稳定性，从而有效收集和检测或消除挥发性有机化合物。
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