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    Wafer-dicing adhesive tape and method of producing chips using the same
    2.
    发明申请
    Wafer-dicing adhesive tape and method of producing chips using the same 有权
    晶片切割胶带和使用其制造芯片的方法

    公开(公告)号：US20080008881A1

    公开(公告)日：2008-01-10

    申请号：US11892905

    申请日：2007-08-28

    申请人： Akira Yabuki ,  Syozo Yano

    发明人： Akira Yabuki ,  Syozo Yano

    IPC分类号： B32B7/12

    CPC分类号： H01L21/67132 ,  C09J4/00 ,  C09J7/22 ,  C09J7/38 ,  C09J7/385 ,  C09J2201/36 ,  C09J2203/326 ,  H01L21/6835 ,  H01L21/6836 ,  H01L2221/68322 ,  H01L2221/68327 ,  Y10T428/28 ,  Y10T428/2891

    摘要： A wafer-dicing adhesive tape, containing two or more removable adhesive layers, on a base film, that have resin compositions containing a radiation-polymerizable compound, in which a content of the radiation-polymerizable compound in the resin composition constituting an outermost removable adhesive layer is different from that of an inner removable adhesive layer and a stress applied to the base film is sufficiently introduced to the outermost removable adhesive layer irradiated with radiation, so that said layer can be easily peeled off from chips cut; and a method of producing chips using the same.

    摘要翻译： 一种在基膜上含有两个或多个可移除粘合剂层的晶片切割粘合带，其具有含有可辐射聚合化合物的树脂组合物，其中构成最外层可去除粘合剂的树脂组合物中的可辐射聚合化合物的含量 层与内部可除去的粘合剂层不同，并且施加到基膜的应力被充分地引入到用辐射照射的最外层可去除的粘合剂层中，使得所述层可以容易地从切割的切屑剥离; 以及使用其制造芯片的方法。

    Solid dispersions or solid dispersion pharmaceutical preparations of phenylalanine derivatives
    3.
    发明申请
    Solid dispersions or solid dispersion pharmaceutical preparations of phenylalanine derivatives 有权

    公开(公告)号：US20060204572A1

    公开(公告)日：2006-09-14

    申请号：US11433589

    申请日：2006-05-15

    申请人： Hiroyuki Higuchi ,  Hirokazu Hagio ,  Kenichi Ogawa ,  Akira Yabuki

    发明人： Hiroyuki Higuchi ,  Hirokazu Hagio ,  Kenichi Ogawa ,  Akira Yabuki

    IPC分类号： A61K31/517 ,  A61K9/20

    CPC分类号： A61K9/14 ,  A61K31/517

    摘要： The present invention provides solid dispersions or solid dispersion pharmaceutical preparations containing a water-soluble polymeric substance(s) and a phenylalanine compound of the formula (1) or pharmaceutically acceptable salts thereof, wherein A represents the formula (2) and the like, B represent an alkoxy group and the like, E represents a hydrogen atom and the like, D represents a substituted phenyl group and the like, T, U and V represent a carbonyl group and the like, Arm represents a benzene ring and the like, R1 represents an alkyl group and the like, R2, R3, and R4 may be the same or different from one another and each represent a hydrogen atom, a substituted amino group and the like, and J and J′ represent a hydrogen atom and the like; production methods thereof; and solubilized pharmaceutical preparations containing a solubilizer(s) and the compound (I) or pharmaceutically acceptable salts thereof. According to the solid dispersion pharmaceutical preparations or solubilized pharmaceutical preparations, though they contain the phenylalanine compound of the formula (1) that is a poorly-soluble drug as an active ingredient, the pharmaceutical preparations having high solubility and oral absorbability can be obtained.

    Solid dispersions or solid dispersion pharmaceutical preparations of phenylalanine derivatives
    5.
    发明授权
    Solid dispersions or solid dispersion pharmaceutical preparations of phenylalanine derivatives 有权
    固体分散体或固体分散体苯丙氨酸衍生物的药物制剂

    公开(公告)号：US08518441B2

    公开(公告)日：2013-08-27

    申请号：US11433589

    申请日：2006-05-15

    申请人： Hiroyuki Higuchi ,  Hirokazu Hagio ,  Kenichi Ogawa ,  Akira Yabuki

    发明人： Hiroyuki Higuchi ,  Hirokazu Hagio ,  Kenichi Ogawa ,  Akira Yabuki

    IPC分类号： A61K9/22 ,  A61K31/517 ,  A61K9/20

    CPC分类号： A61K9/14 ,  A61K31/517

    摘要： The present invention provides solid dispersions or solid dispersion pharmaceutical preparations containing a water-soluble polymeric substance(s) and a phenylalanine compound of the formula (1) or pharmaceutically acceptable salts thereof, wherein A represents the formula (2) and the like, B represent an alkoxy group and the like, E represents a hydrogen atom and the like, D represents a substituted phenyl group and the like, T, U and V represent a carbonyl group and the like, Arm represents a benzene ring and the like, R1 represents an alkyl group and the like, R2, R3, and R4 may be the same or different from one another and each represent a hydrogen atom, a substituted amino group and the like, and J and J′ represent a hydrogen atom and the like; production methods thereof; and solubilized pharmaceutical preparations containing a solubilizer(s) and the compound (I) or pharmaceutically acceptable salts thereof. According to the solid dispersion pharmaceutical preparations or solubilized pharmaceutical preparations, though they contain the phenylalanine compound of the formula (1) that is a poorly-soluble drug as an active ingredient, the pharmaceutical preparations having high solubility and oral absorbability can be obtained.

    摘要翻译： 本发明提供了含有水溶性聚合物和式（1）的苯丙氨酸化合物或其药学上可接受的盐的固体分散体或固体分散体药物制剂，其中A表示式（2）等，B 表示烷氧基等，E表示氢原子等，D表示取代苯基等，T，U和V表示羰基等，Arm表示苯环等，R 1 表示烷基等，R 2，R 3和R 4可以相同或不同，表示氢原子，取代氨基等，J和J'表示氢原子等 ; 生产方法; 和含有增溶剂和化合物（I）的溶解药物制剂或其药学上可接受的盐。 根据固体分散药物制剂或溶解性药物制剂，虽然它们含有作为有效成分的难溶性药物的式（1）的苯丙氨酸化合物，但是可以获得具有高溶解度和口服吸收性的药物制剂。

    Process for producing granules containing branched amino acids
    6.
    发明授权
    Process for producing granules containing branched amino acids 有权
    生产含有支链氨基酸的颗粒的方法

    公开(公告)号：US07138142B2

    公开(公告)日：2006-11-21

    申请号：US10897000

    申请日：2004-07-23

    申请人： Hidetoshi Sakai ,  Mitsuyasu Ida ,  Chisato Makino ,  Tomoaki Kawano ,  Akira Yabuki

    发明人： Hidetoshi Sakai ,  Mitsuyasu Ida ,  Chisato Makino ,  Tomoaki Kawano ,  Akira Yabuki

    IPC分类号： A61K9/14 ,  A61K9/50

    CPC分类号： A61K9/0095 ,  A61K9/1617 ,  A61K9/1635 ,  A61K31/198

    摘要： The problem of the present invention is to provide pharmaceutical granules containing, as active amino acid ingredients, three kinds of branched chain amino acids of isoleucine, leucine and valine, which has a smaller specific volume than conventional products, and a production method thereof. As a result of intensive studies, granules containing, as active amino acid ingredients, three kinds of branched chain amino acids of isoleucine, leucine and valine and a production method thereof have been provided, which are characterized by adding an acid to a particle mixture of three kinds of branched chain amino acids of isoleucine, leucine and valine and granulating the mixture, which has solved the above-mentioned problem.

    摘要翻译： 本发明的问题是提供含有作为活性氨基酸成分的异氰酸，亮氨酸，缬氨酸三种支链氨基酸的药物颗粒，其具有比常规产品更小的比容量及其制备方法。 作为深入研究的结果，提供了含有作为活性氨基酸成分的异亮氨酸，亮氨酸和缬氨酸的三种支链氨基酸的颗粒及其制备方法，其特征在于将酸添加到 3种异亮氨酸，亮氨酸，缬氨酸的支链氨基酸，混合造粒，解决了上述问题。

    Nateglinide-containing preparation
    8.
    发明授权
    Nateglinide-containing preparation 有权
    含那格列奈的制剂

    公开(公告)号：US07732492B2

    公开(公告)日：2010-06-08

    申请号：US11349225

    申请日：2006-02-08

    申请人： Chisato Makino ,  Erika Motomura ,  Kunikazu Suzuki ,  Takahiko Andou ,  Nobutaka Ninomiya ,  Akira Yabuki

    发明人： Chisato Makino ,  Erika Motomura ,  Kunikazu Suzuki ,  Takahiko Andou ,  Nobutaka Ninomiya ,  Akira Yabuki

    IPC分类号： A61K31/13 ,  A61K31/70 ,  A61P3/10

    CPC分类号： A61K31/198 ,  A61K9/2027 ,  A61K9/2054

    摘要： The present invention provides a small-sized preparation that is easy to take, containing 26% or more of nateglinide and 28% or more of at least one disintegrant selected from the group consisting of carmellose or salts thereof, sodium carboxymethyl starch, croscarmellose sodium, crospovidone, partly pregelatinized starch and low-substituted hydroxypropyl cellulose, based on the total mass of the preparation. The preparation of the present invention has high contents of nateglinide, which can be absorbed immediately to exhibit a hypoglycemic action.

    摘要翻译： 本发明提供一种容易服用的小型制剂，其含有所述那格列奈26％或更多，选自羧甲基纤维素或其盐的至少一种崩解剂的28％或更多，羧甲基淀粉钠，交联羧甲基纤维素钠， 交联聚维酮，部分预胶化淀粉和低取代羟丙基纤维素，基于制剂的总质量。 本发明的制剂具有高的那格列奈含量，其可立即被吸收以显示降血糖作用。

    Process for producing granules containing branched amino acids
    9.
    发明申请
    Process for producing granules containing branched amino acids 有权
    生产含有支链氨基酸的颗粒的方法

    公开(公告)号：US20050003015A1

    公开(公告)日：2005-01-06

    申请号：US10897000

    申请日：2004-07-23

    申请人： Hidetoshi Sakai ,  Mitsuyasu Ida ,  Chisato Makino ,  Tomoaki Kawano ,  Akira Yabuki

    发明人： Hidetoshi Sakai ,  Mitsuyasu Ida ,  Chisato Makino ,  Tomoaki Kawano ,  Akira Yabuki

    IPC分类号： A61J3/06 ,  A61K9/00 ,  A61K9/16 ,  A61K31/198 ,  A61K47/04 ,  A61K47/12 ,  A61P1/16 ,  A61K9/14

    CPC分类号： A61K9/0095 ,  A61K9/1617 ,  A61K9/1635 ,  A61K31/198

    摘要： The problem of the present invention is to provide pharmaceutical granules containing, as active amino acid ingredients, three kinds of branched chain amino acids of isoleucine, leucine and valine, which has a smaller specific volume than conventional products, and a production method thereof. As a result of intensive studies, granules containing, as active amino acid ingredients, three kinds of branched chain amino acids of isoleucine, leucine and valine and a production method thereof have been provided, which are characterized by adding an acid to a particle mixture of three kinds of branched chain amino acids of isoleucine, leucine and valine and granulating the mixture, which has solved the above-mentioned problem.

    摘要翻译： 本发明的问题是提供含有作为活性氨基酸成分的异氰酸，亮氨酸，缬氨酸三种支链氨基酸的药物颗粒，其具有比常规产品更小的比容量及其制备方法。 作为深入研究的结果，提供了含有作为活性氨基酸成分的异亮氨酸，亮氨酸和缬氨酸的三种支链氨基酸的颗粒及其制备方法，其特征在于将酸添加到 3种异亮氨酸，亮氨酸，缬氨酸的支链氨基酸，混合造粒，解决了上述问题。