公开(公告)号：US08858632B2

公开(公告)日：2014-10-14

申请号：US11390539

申请日：2006-03-23

Applicant: Kevin Mansmann ,  Peter Popper

Inventor： Kevin Mansmann ,  Peter Popper

IPC: A61F2/30 ,  A61F2/38 ,  A61L27/16 ,  A61L27/18 ,  A61L27/44 ,  A61L27/52 ,  A61F2/46

CPC classification number: A61F2/30756 ,  A61F2/30767 ,  A61F2/3094 ,  A61F2/30965 ,  A61F2/468 ,  A61F2002/30093 ,  A61F2002/302 ,  A61F2002/30457 ,  A61F2002/30892 ,  A61F2002/30914 ,  A61F2002/30957 ,  A61F2002/4635 ,  A61F2210/0019 ,  A61F2220/0058 ,  A61F2230/0065 ,  A61L27/16 ,  A61L27/18 ,  A61L27/446 ,  A61L27/52 ,  A61L2430/06 ,  C08L33/20 ,  C08L75/04

Abstract: Implants with hydrogel layers reinforced by three-dimensional fiber arrays can replace hyaline cartilage. Such implants should replace an entire cartilage segment, rather than creating a crevice around a plug, so these implants must be thin and flat, they must cover large areas, the tips of any tufts or stitches must not reach the hydrogel surface, and they must be flexible, for arthroscopic insertion. The use of computerized stitching machines to create such arrays enables a redesigned and modified test sample to be made with no delays, and no overhead or startup costs. This provides researchers with improved tools for making and testing implants that will need to go through extensive in vitro, animal, and human testing before they can be approved for sale and use. Fiber-reinforced hydrogels also can be secured to strong shape-memory rims, for securing anchoring to bones.

Abstract translation: 具有由三维纤维阵列增强的水凝胶层的植入物可以代替透明软骨。 这种植入物应该替代整个软骨部分，而不是在塞子周围产生缝隙，因此这些植入物必须薄而扁平，它们必须覆盖大面积，任何簇或针迹的尖端不能到达水凝胶表面，并且它们必须 灵活，用于关节镜插入。 使用计算机缝纫机创建这样的阵列可以重新设计和修改测试样品，而不会产生任何延迟，也不会产生开销或启动成本。 这为研究人员提供了用于制造和测试植入物的改进工具，需要经过广泛的体外，动物和人体测试才能被批准出售和使用。 纤维增强水凝胶也可以固定到牢固的形状记忆轮缘，用于固定锚固到骨头。

公开(公告)号：US20070224238A1

公开(公告)日：2007-09-27

申请号：US11390539

申请日：2006-03-23

Applicant: Kevin Mansmann ,  Peter Popper

Inventor： Kevin Mansmann ,  Peter Popper

IPC: A61F2/28

CPC classification number: A61F2/30756 ,  A61F2/30767 ,  A61F2/3094 ,  A61F2/30965 ,  A61F2/468 ,  A61F2002/30093 ,  A61F2002/302 ,  A61F2002/30457 ,  A61F2002/30892 ,  A61F2002/30914 ,  A61F2002/30957 ,  A61F2002/4635 ,  A61F2210/0019 ,  A61F2220/0058 ,  A61F2230/0065 ,  A61L27/16 ,  A61L27/18 ,  A61L27/446 ,  A61L27/52 ,  A61L2430/06 ,  C08L33/20 ,  C08L75/04

Abstract: Implants with hydrogel layers reinforced by three-dimensional fiber arrays can replace hyaline cartilage. Such implants should replace an entire cartilage segment, rather than creating a crevice around a plug, so these implants must be thin and flat, they must cover large areas, the tips of any tufts or stitches must not reach the hydrogel surface, and they must be flexible, for arthroscopic insertion. The use of computerized stitching machines to create such arrays enables a redesigned and modified test sample to be made with no delays, and no overhead or startup costs. This provides researchers with improved tools for making and testing implants that will need to go through extensive in vitro, animal, and human testing before they can be approved for sale and use. Fiber-reinforced hydrogels also can be secured to strong shape-memory rims, for securing anchoring to bones.

Abstract translation: 具有由三维纤维阵列增强的水凝胶层的植入物可以代替透明软骨。 这种植入物应该替代整个软骨部分，而不是在塞子周围产生缝隙，因此这些植入物必须薄而扁平，它们必须覆盖大面积，任何簇或针迹的尖端不能到达水凝胶表面，并且它们必须 灵活，用于关节镜插入。 使用计算机缝纫机创建这样的阵列可以重新设计和修改测试样品，而不会产生任何延迟，也不会产生开销或启动成本。 这为研究人员提供了用于制造和测试植入物的改进工具，需要经过广泛的体外，动物和人体测试才能被批准出售和使用。 纤维增强水凝胶也可以固定到牢固的形状记忆轮缘，用于固定锚固到骨头。

公开(公告)号：US20050287187A1

公开(公告)日：2005-12-29

申请号：US11105677

申请日：2005-04-14

Applicant: Kevin Mansmann

Inventor： Kevin Mansmann

IPC: A61F2/00 ,  A61F2/02 ,  A61F2/08 ,  A61F2/30 ,  A61F2/32 ,  A61F2/38 ,  A61F2/40 ,  A61F2/42 ,  A61F2/46

CPC classification number: A61F2/30749 ,  A61F2/30756 ,  A61F2/30965 ,  A61F2/32 ,  A61F2/40 ,  A61F2/4241 ,  A61F2/4261 ,  A61F2/468 ,  A61F2002/30006 ,  A61F2002/30062 ,  A61F2002/30382 ,  A61F2002/30489 ,  A61F2002/30594 ,  A61F2002/30751 ,  A61F2002/30892 ,  A61F2002/30894 ,  A61F2002/3895 ,  A61F2002/4631 ,  A61F2210/0004 ,  A61F2220/0008 ,  A61F2220/0025 ,  A61F2220/0033 ,  A61F2250/0015 ,  A61L27/14 ,  A61L27/50 ,  A61L27/52 ,  A61L2400/10 ,  A61L2400/18 ,  A61L2430/06 ,  A61L2430/24

Abstract: Hydrogel devices for surgical implantation to replace damaged cartilage in a mammalian joint (such as a knee, hip, shoulder, etc.) are disclosed, with one or more of the following enhancements: (1) articulating surfaces that have been given negative surface charge densities that emulate natural cartilage and that interact with positively charged components of synovial fluid; (2) anchoring systems with affixed pegs that will lock into accommodating receptacles, which will be anchored into hard bone before the implant is inserted into a joint; (3) a three-dimensional reinforcing mesh made of strong but flexible fibers, embedded within at least a portion of the hydrogel.

Abstract translation: 公开了用于手术植入以替代哺乳动物关节（例如膝盖，髋部，肩部等）中的受损软骨的水凝胶装置，具有以下一个或多个增强：（1）已经被赋予负表面电荷的关节表面 模拟天然软骨的密度并与滑液中带正电荷的组分相互作用; （2）具有固定钉的锚定系统，其将锁定到容纳容器中，其将在将植入物插入关节之前锚固到硬骨中; （3）由坚固且柔软的纤维制成的三维增强网，其嵌入在至少一部分水凝胶中。

公开(公告)号：US20070118135A1

公开(公告)日：2007-05-24

申请号：US11521939

申请日：2006-09-15

Applicant: Kevin Mansmann

Inventor： Kevin Mansmann

IPC: A61B17/00

CPC classification number: A61B17/1633 ,  A61B17/16 ,  A61B17/1624 ,  A61B17/1662 ,  A61B17/32002 ,  A61B2017/1602 ,  A61B2217/005

Abstract: Surgical tools are disclosed for minimally-invasive planing of bone surfaces that will support prosthetic implants, such as cartilage-repair implants. Such planing tools must create smooth surfaces that will closely fit the anchoring surface of an implant. Such tools can use a rotating cylindrical burr, partially covered by a cowl having adjustable components to control grinding depth and bone curvature. Burrs can be mounted on the ends of rotating shafts, or they can be angled, using drive-coupling interfaces. In other embodiments, shaver or burr tools can be supplemented by accessory-type devices (such as suction tubes, cautery tips, and pinchers) that can be extended beyond the normal working tip of a tool, to enable additional functions that will be useful during surgery.

Abstract translation: 公开了外科手术工具用于骨支撑的微创刨削，其将支持假体植入物，例如软骨修复植入物。 这种刨削工具必须产生将与植入物的锚固表面紧密配合的光滑表面。 这样的工具可以使用旋转的圆柱形毛刺，其部分地由具有可调节部件的整流罩覆盖以控制研磨深度和骨弯曲。 毛刺可以安装在旋转轴的端部上，也可以使用驱动耦合接口进行倾斜。 在其他实施例中，剃须刀或毛刺工具可以由可以延伸超出工具的正常工作尖端的附件型装置（例如抽吸管，烧灼尖端和夹持器）补充，以实现在 手术。