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公开(公告)号：US10449349B2
公开(公告)日：2019-10-22
申请号：US15379346
申请日：2016-12-14
Applicant: L'Oreal
Inventor： James Christopher McInnes , John Streeter , Vincenzo Casasanta, III
Abstract: Single layer and multilayer vesicles with actives inside are delivered into living tissue. Then, the vesicles are disrupted using ultrasound. The vesicles are used to create an image in the tissue or for the delivery of certain actives to the skin.
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公开(公告)号：US10039600B2
公开(公告)日：2018-08-07
申请号：US14613059
申请日：2015-02-03
Applicant: L'OREAL
Inventor： Iranpour Khormaei , Lilac Muller , James Christopher McInnes
Abstract: An apparatus and method is provided for skin treatment. An apparatus includes an applicator assembly that includes an applicator tip which is configured to apply a normal cyclical mechanical force to a skin surface area of a user and to deliver a skin formulation to a skin surface area of a user. The apparatus further includes an electromagnetic energy assembly that includes at least one electromagnetic energy source adjacent to or within the applicator assembly and is configured to deliver pulses of electromagnetic energy stimulus of a character and for a duration sufficient to penetrate one or more dermal layers within the skin surface area of a use.
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Patent Agency Ranking
公开(公告)号：US09687643B2
公开(公告)日：2017-06-27
申请号：US14613125
申请日：2015-02-03
Applicant: L'OREAL
Inventor： Iranpour Khormaei , Lilac Muller , James Christopher McInnes
CPC classification number: A61M37/0092 , A61B18/18 , A61B2017/00172 , A61B2018/00458 , A61B2018/0091 , A61B2018/1807 , A61M2037/0007 , A61N5/0616 , A61N5/062 , A61N2005/0644 , A61N2005/0652 , A61N2005/0659 , A61N2005/0662 , A61N2005/0663
Abstract: An apparatus and method is provided for skin treatment. The apparatus includes an applicator assembly that includes an applicator tip which is configured to apply a normal cyclical mechanical force to a skin surface area of a user and to deliver a skin formulation to a skin surface area of a user. The apparatus further includes an electromagnetic energy assembly that includes at least one electromagnetic energy source adjacent to or within the applicator assembly and configured to deliver a continuous electromagnetic energy stimulus of a character and for a duration sufficient to penetrate one or more dermal layers within the skin surface area of a user.
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4.发明申请公开(公告)号：US20150265825A1
公开(公告)日：2015-09-24
申请号：US14222327
申请日：2014-03-21
Applicant: L'Oreal
CPC classification number: A61M37/0092 , A46B13/023 , A46B13/04 , A46B15/0022 , A46B2200/102 , A47K7/043 , A61H7/005 , A61H23/02 , A61H23/0236 , A61H23/0245 , A61H23/04 , A61H2201/0153 , A61H2201/10 , A61H2201/105 , A61H2201/1685 , A61H2201/1692 , A61K9/0009 , A61M35/003 , A61M2205/058 , A61N1/044 , A61N1/0472 , A61N1/26 , A61N1/303 , A61N1/322 , A61N1/325
Abstract: The present disclosure seeks to address the primary problem of long application durations to deliver an effective dose of an active ingredient. The devices combine mechanical motion with electrically induced flux (e.g., iontophoresis). The combination of techniques in a single device can reduce the treatment time required to deliver the active ingredient in an effective dose, or deliver a larger dose over the same duration of application.
Abstract translation: 本公开旨在解决长期使用持续时间以提供有效剂量的活性成分的主要问题。 这些装置将机械运动与电感应通量结合（例如离子电渗疗法）。 单一装置中技术的组合可以减少以有效剂量递送活性成分所需的治疗时间，或者在相同的施用持续时间内递送更大的剂量。
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公开(公告)号：US20180161564A1
公开(公告)日：2018-06-14
申请号：US15379346
申请日：2016-12-14
Applicant: L'Oreal
Inventor： James Christopher McInnes , John Streeter , Vincenzo Casasanta, III
Abstract: Single layer and multilayer vesicles with actives inside are delivered into living tissue. Then, the vesicles are disrupted using ultrasound. The vesicles are used to create an image in the tissue or for the delivery of certain actives to the skin.
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公开(公告)号：US20160184162A1
公开(公告)日：2016-06-30
申请号：US14586490
申请日：2014-12-30
Applicant: L'Oreal
Inventor： Joseph W. Grez , Zane Bowman Allen Miller , Vincenzo Casasanta, III , James Christopher McInnes
CPC classification number: A61F7/00 , A46B5/0095 , A46B9/06 , A46B13/023 , A46B15/0028 , A46B15/003 , A46B2200/102 , A61F7/007 , A61F2007/0052 , A61F2007/0071 , A61H7/005 , A61H23/0236 , A61H2201/0207 , A61H2201/0221 , A61H2201/0235 , A61H2201/10 , A61H2201/105 , A61H2201/1635 , A61H2201/1664 , A61H2201/1671 , A61H2201/1685 , A61H2201/5005 , A61H2201/5035 , A61H2201/5082
Abstract: An applicator for use in treating a portion of skin includes an applicator tip that has an end configured to contact the portion of skin, a sonic source mechanically coupled to the applicator tip, a heat source thermally coupled to an end of the applicator tip, and a controller. The applicator tip includes a thermally-conductive material. During operation of the applicator, the controller controls operation of the sonic source to impart mechanical movements to the applicator tip at a sonic frequency and controls operation of the heat source to transfer heat to the end of the applicator tip via the thermally-conductive material of the applicator tip.
Abstract translation: 用于治疗皮肤部分的施用器包括：施用器末端，其具有构造成接触皮肤部分的端部，机械耦合到施用器尖端的声源，热耦合到施用器尖端的热源，以及 一个控制器 施用器尖端包括导热材料。 在施加器的操作期间，控制器控制声源的操作，以声频给予施加器尖端的机械运动，并且控制热源的操作，以通过热传导材料将热量传递到施用器尖端的端部 涂抹器尖端。
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公开(公告)号：US20150174387A1
公开(公告)日：2015-06-25
申请号：US14139423
申请日：2013-12-23
Applicant: L'Oreal
Inventor： James Christopher McInnes , Ken Pilcher , Zane Miller
IPC: A61M37/00
CPC classification number: A61M37/0092 , A61H23/00 , A61H23/02 , A61H23/0245 , A61H2023/0227 , A61H2201/0153 , A61H2201/1692 , A61M35/00 , A61M35/003 , A61M2037/0007 , A61M2205/058 , A61M2205/106 , A61M2210/04
Abstract: Dermal infusion devices and methods are provided. The device is configured to direct two different frequencies of oscillating motion (e.g., sonic and ultrasonic) towards the skin of a subject. The combination of the two different frequencies results in improved dermal infusion capabilities and can be used, for example, to effect transdermal delivery of a topical formulation.
Abstract translation: 提供了皮肤输注装置和方法。 该装置被配置为将两个不同的振荡运动频率（例如声波和超声波）引导到被摄体的皮肤。 两种不同频率的组合导致改善的皮肤输注能力，并且可以用于例如局部制剂的透皮递送。
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