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1.
公开(公告)号:US20200166503A1
公开(公告)日:2020-05-28
申请号:US16695647
申请日:2019-11-26
Applicant: Massachusetts Institute of Technology
Inventor: Timothy Manning Swager , Qifan Zhang , Lukas Zeininger
Abstract: Embodiments described herein may be useful in the detection of analytes. The systems and methods may allow for a relatively simple and rapid way for detecting analytes such as chemical and/or biological analytes and may be useful in numerous applications including sensing, food manufacturing, medical diagnostics, performance materials, dynamic lenses, water monitoring, environmental monitoring, detection of proteins, detection of DNA, among other applications.
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公开(公告)号:US11654404B2
公开(公告)日:2023-05-23
申请号:US16415353
申请日:2019-05-17
Applicant: Massachusetts Institute of Technology
Inventor: Timothy M. Swager , Sara N. Nagelberg , Mathias Kolle , Lukas Zeininger , Kent Harvey , Myles Herbert
CPC classification number: B01F23/41 , B01F25/14 , B01L3/502784 , G01N21/1717 , G01N21/25 , G01N21/59 , B01F23/4145 , G01N21/47 , G01N21/55
Abstract: Embodiments described herein may be useful for optofluidic devices. For example, optofluidic devices using dynamic fluid lens materials represent an ideal platform to create versatile, reconfigurable, refractive optical components. For example, the articles described herein may be useful as fluidic tunable compound micro-lenses. Such compound micro-lenses may be composed of two or more components (e.g., two or more inner phases) that form stable bi-phase emulsion droplets in outer phases (e.g., aqueous media). In some embodiments, the articles described herein may be useful as light emitting droplets. Advantageously, the plurality of droplets may be configured such that light rays may modified (e.g., via stimulation of the droplets, exposure to an analyte such as a pathogen) to have a detectable emission intensity and/or angle of maximum emission intensity under a particular set of conditions.
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3.
公开(公告)号:US12061194B2
公开(公告)日:2024-08-13
申请号:US17545979
申请日:2021-12-08
Applicant: Massachusetts Institute of Technology
Inventor: Timothy Manning Swager , Hadley Sikes Johnson , Qifan Zhang , Eric Alexander Miller , Lukas Zeininger , Ki-Joo Sung , Kosuke Yoshinaga
IPC: G01N21/77 , C12Q1/6834 , C12Q1/70 , G01N21/59 , G01N33/543 , G01N33/569 , G01N21/78
CPC classification number: G01N33/5432 , C12Q1/6834 , C12Q1/701 , G01N21/59 , G01N21/77 , G01N33/54366 , G01N33/56983 , G01N2021/7783 , G01N21/78 , G01N2201/0221 , C12Q1/701 , C12Q2563/159
Abstract: Embodiments described herein may be useful in the detection of analytes. The systems and methods may allow for a relatively simple and rapid way for detecting analytes such as chemical and/or biological analytes and may be useful in numerous applications including sensing, food manufacturing, medical diagnostics, performance materials, dynamic lenses, water monitoring, environmental monitoring, detection of proteins, detection of DNA, among other applications. For example, the systems and methods described herein may be used for determining the presence of a contaminant such as bacteria (e.g., detecting pathogenic bacteria in food and water samples which helps to prevent widespread infection, illness, and even death). Advantageously, the systems and methods described herein may not have the drawbacks in current detection technologies including, for example, relatively high costs, long enrichment steps and analysis times, and/or the need for extensive user training. Another advantageous feature provided by the systems and methods described herein includes fabrication in a relatively large scale. In some embodiments, the systems and methods may be used in conjunction with a detector including handheld detectors incorporated with, for example, smartphones (e.g., for the on-site detection of analytes such as pathogenic bacteria).
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公开(公告)号:US20220205989A1
公开(公告)日:2022-06-30
申请号:US17545979
申请日:2021-12-08
Applicant: Massachusetts Institute of Technology
Inventor: Timothy Manning Swager , Hadley Sikes Johnson , Qifan Zhang , Eric Alexander Miller , Lukas Zeininger , Ki-Joo Sung , Kosuke Yoshinaga
IPC: G01N33/543 , G01N21/59 , G01N21/77 , C12Q1/6834 , C12Q1/70 , G01N33/569
Abstract: Embodiments described herein may be useful in the detection of analytes. The systems and methods may allow for a relatively simple and rapid way for detecting analytes such as chemical and/or biological analytes and may be useful in numerous applications including sensing, food manufacturing, medical diagnostics, performance materials, dynamic lenses, water monitoring, environmental monitoring, detection of proteins, detection of DNA, among other applications. For example, the systems and methods described herein may be used for determining the presence of a contaminant such as bacteria (e.g., detecting pathogenic bacteria in food and water samples which helps to prevent widespread infection, illness, and even death). Advantageously, the systems and methods described herein may not have the drawbacks in current detection technologies including, for example, relatively high costs, long enrichment steps and analysis times, and/or the need for extensive user training. Another advantageous feature provided by the systems and methods described herein includes fabrication in a relatively large scale. In some embodiments, the systems and methods may be used in conjunction with a detector including handheld detectors incorporated with, for example, smartphones (e.g., for the on-site detection of analytes such as pathogenic bacteria).
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公开(公告)号:US20200301027A9
公开(公告)日:2020-09-24
申请号:US16358340
申请日:2019-03-19
Applicant: Massachusetts Institute of Technology
Inventor: Timothy M. Swager , Maggie He , Lukas Zeininger
Abstract: Compositions, devices, and methods for determining ionizing radiation are generally described.
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公开(公告)号:US20190388849A1
公开(公告)日:2019-12-26
申请号:US16415353
申请日:2019-05-17
Applicant: Massachusetts Institute of Technology
Inventor: Timothy M. Swager , Sara N. Nagelberg , Mathias Kolle , Lukas Zeininger , Kent Harvey , Myles Herbert
Abstract: Embodiments described herein may be useful for optofluidic devices. For example, optofluidic devices using dynamic fluid lens materials represent an ideal platform to create versatile, reconfigurable, refractive optical components. For example, the articles described herein may be useful as fluidic tunable compound micro-lenses. Such compound micro-lenses may be composed of two or more components (e.g., two or more inner phases) that form stable bi-phase emulsion droplets in outer phases (e.g., aqueous media). In some embodiments, the articles described herein may be useful as light emitting droplets. Advantageously, the plurality of droplets may be configured such that light rays may modified (e.g., via stimulation of the droplets, exposure to an analyte such as a pathogen) to have a detectable emission intensity and/or angle of maximum emission intensity under a particular set of conditions.
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公开(公告)号:US20190285757A1
公开(公告)日:2019-09-19
申请号:US16358340
申请日:2019-03-19
Applicant: Massachusetts Institute of Technology
Inventor: Timothy M. Swager , Maggie He , Lukas Zeininger
Abstract: Compositions, devices, and methods for determining ionizing radiation are generally described.
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公开(公告)号:US20190170737A1
公开(公告)日:2019-06-06
申请号:US16202007
申请日:2018-11-27
Applicant: Massachusetts Institute of Technology
Inventor: Timothy M. Swager , Hadley Sikes Johnson , Qifan Zhang , Eric Alexander Miller , Lukas Zeininger , Ki-Joo Sung , Kosuke Yoshinaga
IPC: G01N33/543 , G01N21/59 , C12Q1/6834 , G01N21/77
Abstract: Embodiments described herein may be useful in the detection of analytes. The systems and methods may allow for a relatively simple and rapid way for detecting analytes such as chemical and/or biological analytes and may be useful in numerous applications including sensing, food manufacturing, medical diagnostics, performance materials, dynamic lenses, water monitoring, environmental monitoring, detection of proteins, detection of DNA, among other applications. For example, the systems and methods described herein may be used for determining the presence of a contaminant such as bacteria (e.g., detecting pathogenic bacteria in food and water samples which helps to prevent widespread infection, illness, and even death). Advantageously, the systems and methods described herein may not have the drawbacks in current detection technologies including, for example, relatively high costs, long enrichment steps and analysis times, and/or the need for extensive user training. Another advantageous feature provided by the systems and methods described herein includes fabrication in a relatively large scale. In some embodiments, the systems and methods may be used in conjunction with a detector including handheld detectors incorporated with, for example, smartphones (e.g., for the on-site detection of analytes such as pathogenic bacteria).
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