公开(公告)号：US20220365106A1

公开(公告)日：2022-11-17

申请号：US17679663

申请日：2022-02-24

申请人： Meso Scale Technologies, LLC.

发明人： Manish KOCHAR ,  Peter J. BOSCO ,  Ian D. CHAMBERLIN ,  Bandele JEFFREY-COKER ,  Eric M. JONES ,  Gary I. KRIVOY ,  Don E. KRUEGER ,  Aaron H. LEIMKUEHLER ,  Pei-Ming WU ,  Kim-Xuan NGUYEN ,  Pankaj OBEROI ,  Louis W. PANG ,  Jennifer PARKER ,  Victor PELLICIER ,  Nicholas SAMMONS ,  George SIGAL ,  Jacob N. WOHLSTADTER ,  Michael L. VOCK ,  Stanley T. SMITH ,  Carl C. STEVENS ,  Rodger D. OSBORNE ,  Kenneth E. PAGE ,  Michael T. WADE ,  Jon WILLOUGHBY ,  Lei WANG

IPC分类号： G01N35/00 ,  B01L3/00 ,  B01L9/00 ,  G16H40/67 ,  G16H10/40 ,  G16H40/40 ,  F24F11/30 ,  G06K7/14 ,  G06Q10/08 ,  G06Q10/10

摘要： The present invention relates to methods, devices and systems for associating consumable data with an assay consumable used in a biological assay. Provided are assay systems and associated consumables, wherein the assay system adjusts one or more steps of an assay protocol based on consumable data specific for that consumable. Various types of consumable data are described, as well as methods of using such data in the conduct of an assay by an assay system. The present invention also relates to consumables (e.g., kits and reagent containers), software, data deployable bundles, computer-readable media, loading carts, instruments, systems, and methods, for performing automated biological assays.

公开(公告)号：US20240226904A1

公开(公告)日：2024-07-11

申请号：US18405433

申请日：2024-01-05

申请人： MESO SCALE TECHNOLOGIES, LLC.

发明人： Gary I. KRIVOY ,  Cecilia ZIMMERMAN ,  Jules VANDERSARL ,  Sandor KOVACS ,  Aaron H. LEIMKUEHLER ,  Leo TABAKIN ,  Jon WILLOUGHBY ,  Manish KOCHAR ,  Charles M. CLINTON

IPC分类号： B01L9/00

CPC分类号： B01L9/523 ,  B01L2300/0654 ,  B01L2300/0663 ,  B01L2300/0829 ,  B01L2300/168 ,  B01L2300/1844 ,  B01L2300/1894

摘要： Apparatuses, systems, method, reagents, and kits for conducting assays as well as process for their preparation are described. The apparatuses, systems, method, reagents, and kits may be employed in conducting automated analysis in a multi-well plate assay format.

公开(公告)号：US20210389338A1

公开(公告)日：2021-12-16

申请号：US17412688

申请日：2021-08-26

申请人： Meso Scale Technologies, LLC.

发明人： Manish KOCHAR ,  Peter J. BOSCO ,  Ian D. CHAMBERLIN ,  Bandele JEFFREY-COKER ,  Eric M. JONES ,  Gary I. KRIVOY ,  Aaron H. LEIMKUEHLER ,  Pei-Ming WU ,  Kim-Xuan NGUYEN ,  Pankaj OBEROI ,  Louis W. PANG ,  Jennifer PARKER ,  Victor PELLICIER ,  Nicholas SAMMONS ,  George SIGAL ,  Jacob N. WOHLSTADTER ,  Michael L. VOCK ,  Stanley T. SMITH ,  Carl C. STEVENS ,  Rodger D. OSBORNE ,  Kenneth E. PAGE ,  Michael T. WADE ,  Jon WILLOUGHBY ,  Lei WANG ,  Don E. KRUEGER

IPC分类号： G01N35/00 ,  B01L3/00 ,  B01L9/00 ,  G16H40/67 ,  G16H10/40 ,  G16H40/40 ,  F24F11/30 ,  G06K7/14 ,  G06Q10/08 ,  G06Q10/10

摘要： The present invention relates to methods, devices and systems for associating consumable data with an assay consumable used in a biological assay. Provided are assay systems and associated consumables, wherein the assay system adjusts one or more steps of an assay protocol based on consumable data specific for that consumable. Various types of consumable data are described, as well as methods of using such data in the conduct of an assay by an assay system. The present invention also relates to consumables (e.g., kits and reagent containers), software, data deployable bundles, computer-readable media, loading carts, instruments, systems, and methods, for performing automated biological assays.

公开(公告)号：US20240286293A1

公开(公告)日：2024-08-29

申请号：US18585520

申请日：2024-02-23

申请人： Meso Scale Technologies, LLC.

发明人： Slavi MIRTCHEV ,  Gary I. KRIVOY ,  Manish KOCHAR ,  Aaron H. LEIMKUEHLER

IPC分类号： B25J15/00 ,  G01N35/00

CPC分类号： B25J15/0028 ,  G01N35/0099

摘要： A gripper assembly for a robotic arm includes a gripper finger having a first end and a second end, a gripper pad pivotably coupled to the gripper finger such that the gripper pad is permitted to rotate about a rotational axis relative to the gripper finger, the gripper pad having a pair of sides with one of the sides forming a gripping surface configured to grip an object, and a proximal side located between the pair of sides, and a gripper pad aligner including a pad alignment element coupled to the gripper pad and a finger alignment element coupled to the gripper finger, wherein the pad alignment element is coupled to the finger alignment element and configured to apply an aligning torque to the gripper pad that, when applied, rotates the gripper pad toward a first angular orientation about the rotational axis between the gripper pad and the gripper finger.

公开(公告)号：US20210016288A1

公开(公告)日：2021-01-21

申请号：US16929757

申请日：2020-07-15

申请人： Meso Scale Technologies, LLC.

发明人： Gary I. KRIVOY ,  Cecilia ZIMMERMAN ,  Jules VANDERSARL ,  Sandor KOVACS ,  Aaron H. LEIMKUEHLER ,  Leo TABAKIN ,  Jon WILLOUGHBY ,  Manish KOCHAR ,  Charles M. Clinton

IPC分类号： B01L9/00

摘要： Apparatuses, systems, method, reagents, and kits for conducting assays as well as process for their preparation are described. The apparatuses, systems, method, reagents, and kits may be employed in conducting automated analysis in a multi-well plate assay format.

公开(公告)号：US20240094233A1

公开(公告)日：2024-03-21

申请号：US18354382

申请日：2023-07-18

申请人： MESO SCALE TECHNOLOGIES, LLC.

发明人： Jacob N. WOHLSTADTER ,  Manish KOCHAR ,  Peter J. BOSCO ,  Ian D. CHAMBERLIN ,  Bandele JEFFREY-COKER ,  Eric M. JONES ,  Gary I. KRIVOY ,  Don E. KRUEGER ,  Aaron H. LEIMKUEHLER ,  Pei-Ming WU ,  Kim-Xuan NGUYEN ,  Pankaj OBEROI ,  Louis W. PANG ,  Jennifer PARKER ,  Victor PELLICIER ,  Nicholas SAMMONS ,  George SIGAL ,  Michael L. VOCK ,  Stanley T. SMITH ,  Carl C. STEVENS ,  Rodger D. OSBORNE ,  Kenneth E. PAGE ,  Michael T. WADE ,  Jon WILLOUGHBY ,  Lei WANG ,  Xinri CONG ,  Kin NG

IPC分类号： G01N35/00 ,  B01L3/00 ,  B01L9/00 ,  F24F11/30 ,  G06K7/14 ,  G06Q10/087 ,  G06Q10/10 ,  G16H10/40 ,  G16H40/40 ,  G16H40/67

CPC分类号： G01N35/0099 ,  B01L3/50853 ,  B01L9/523 ,  F24F11/30 ,  G06K7/1413 ,  G06Q10/087 ,  G06Q10/10 ,  G16H10/40 ,  G16H40/40 ,  G16H40/67 ,  B01L2200/143 ,  B01L2300/021 ,  G01N2035/00356 ,  G05B2219/40269 ,  H04B1/3827

摘要： The present invention relates to methods, devices and systems for associating consumable data with an assay consumable used in a biological assay. Provided are assay systems and associated consumables, wherein the assay system adjusts one or more steps of an assay protocol based on consumable data specific for that consumable. Various types of consumable data are described, as well as methods of using such data in the conduct of an assay by an assay system. The present invention also relates to consumables (e.g., kits and reagent containers), software, data deployable bundles, computer-readable media, loading carts, instruments, systems, and methods, for performing automated biological assays.

公开(公告)号：US20240003925A1

公开(公告)日：2024-01-04

申请号：US18323082

申请日：2023-05-24

申请人： MESO SCALE TECHNOLOGIES, LLC.

发明人： Manish KOCHAR ,  Peter J. BOSCO ,  Ian D. CHAMBERLIN ,  Bandele JEFFREY-COKER ,  Eric M. JONES ,  Gary I. KRIVOY ,  Aaron H. LEIMKUEHLER ,  Pei-Ming WU ,  Kim-Xuan NGUYEN ,  Pankaj OBEROI ,  Louis W. PANG ,  Jennifer PARKER ,  Victor PELLICIER ,  Nicholas SAMMONS ,  George SIGAL ,  Jacob N. WOHLSTADTER ,  Michael L. VOCK ,  Stanley Todd SMITH ,  Carl C. STEVENS ,  Rodger D. OSBORNE ,  Kenneth E. PAGE ,  Michael T. WADE ,  Jon WILLOUGHBY ,  Lei WANG ,  Don E. KRUEGER

IPC分类号： G01N35/00 ,  B01L3/00 ,  B01L9/00 ,  G16H40/67 ,  G16H10/40 ,  G16H40/40 ,  F24F11/30 ,  G06K7/14 ,  G06Q10/087 ,  G06Q10/10

CPC分类号： G01N35/0099 ,  B01L3/50853 ,  B01L9/523 ,  G16H40/67 ,  G16H10/40 ,  G16H40/40 ,  F24F11/30 ,  G06K7/1413 ,  G06Q10/087 ,  G06Q10/10 ,  B01L2200/143 ,  B01L2300/021 ,  G01N2035/00356 ,  G05B2219/40269 ,  H04B1/3827

摘要： The present invention relates to methods, devices and systems for associating consumable data with an assay consumable used in a biological assay. Provided are assay systems and associated consumables, wherein the assay system adjusts one or more steps of an assay protocol based on consumable data specific for that consumable. Various types of consumable data are described, as well as methods of using such data in the conduct of an assay by an assay system. The present invention also relates to consumables (e.g., kits and reagent containers), software, data deployable bundles, computer-readable media, loading carts, instruments, systems, and methods, for performing automated biological assays.

公开(公告)号：US20220244188A1

公开(公告)日：2022-08-04

申请号：US17603771

申请日：2020-04-22

申请人： Gary I. KRIVOY ,  Cecilia ZIMMERMAN ,  Jules VANDERDARL ,  Sandor KOVACS ,  Aaron LEIMKUEHLER ,  Leo TABAKIN ,  Jon WILLOUGHBY ,  Manish KOCHAR ,  Charles M. CLINTON ,  Meso Scale Technologies, LLC.

发明人： Gary I. KRIVOY ,  Cecilia ZIMMERMAN ,  Jules VANDERSARL ,  Sandor KOVACS ,  Aaron LEIMKUEHLER ,  Leo TABAKIN ,  Jon WILLOUGHBY ,  Manish KOCHAR ,  Charles M. CLINTON

IPC分类号： G01N21/76 ,  G01N35/02 ,  G01N35/00

摘要： Apparatuses, systems, method, reagents, and kits for conducting assays as well as process for their preparation ar described. They are particularly well suited for conducting automated analysis in a multi-well plate assay format. Also disclosed are systems, devices, and methods provided herein for using a CCD camera based system to generate measurements having reduced crosstalk between measurements of multiple spatially separated subjects. CCD camera based systems as provided herein use improved reference level clamping circuits configured to fully reset reference levels during CCD readout, thereby reducing a level of crosstalk between measurements.