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公开(公告)号:US20110053188A1
公开(公告)日:2011-03-03
申请号:US10583415
申请日:2004-12-20
申请人: Roman Meyer , Michael Schütz , Holger Grallert , Renate Grassl , Stefan Miller
发明人: Roman Meyer , Michael Schütz , Holger Grallert , Renate Grassl , Stefan Miller
CPC分类号: G01N33/92 , G01N33/56911 , G01N2400/50 , Y10T436/10
摘要: The invention relates to a method for detecting endotoxins in a sample.
摘要翻译: 本发明涉及检测样品中内毒素的方法。
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公开(公告)号:US07585620B2
公开(公告)日:2009-09-08
申请号:US10519259
申请日:2003-06-24
申请人: Michael Schütz , Roman Meyer , Holger Grallert , Stefan Miller
发明人: Michael Schütz , Roman Meyer , Holger Grallert , Stefan Miller
CPC分类号: G01N33/569 , G01N33/566
摘要: The invention relates to a method for identifying endotoxins for eliminating said endotoxins from a sample, with the aid of bacteriophage tail proteins.
摘要翻译: 本发明涉及用噬菌体尾蛋白鉴定内毒素从样品中去除所述内毒素的方法。
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公开(公告)号:US07858299B2
公开(公告)日:2010-12-28
申请号:US12510540
申请日:2009-07-28
申请人: Michael Schütz , Roman Meyer , Holger Grallert , Stefan Miller
发明人: Michael Schütz , Roman Meyer , Holger Grallert , Stefan Miller
CPC分类号: G01N33/569 , G01N33/566
摘要: The invention relates to a method for identifying endotoxins for eliminating said endotoxins from a sample, with the aid of bacteriophage tail proteins.
摘要翻译: 本发明涉及用噬菌体尾蛋白鉴定内毒素从样品中去除所述内毒素的方法。
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公开(公告)号:US20100028857A1
公开(公告)日:2010-02-04
申请号:US12510540
申请日:2009-07-28
申请人: Michael Schütz , Roman Meyer , Holger Grallert , Stefan Miller
发明人: Michael Schütz , Roman Meyer , Holger Grallert , Stefan Miller
CPC分类号: G01N33/569 , G01N33/566
摘要: The invention relates to a method for identifying endotoxins for eliminating said endotoxins from a sample, with the aid of bacteriophage tail proteins.
摘要翻译: 本发明涉及用噬菌体尾蛋白鉴定内毒素从样品中去除所述内毒素的方法。
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公开(公告)号:US08394597B2
公开(公告)日:2013-03-12
申请号:US10583415
申请日:2004-12-20
申请人: Roman Meyer , Michael Schütz , Holger Grallert , Renate Grassl , Stefan Miller
发明人: Roman Meyer , Michael Schütz , Holger Grallert , Renate Grassl , Stefan Miller
CPC分类号: G01N33/92 , G01N33/56911 , G01N2400/50 , Y10T436/10
摘要: The invention relates to a method for detecting endotoxins in a sample.
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公开(公告)号:US08329393B2
公开(公告)日:2012-12-11
申请号:US13181199
申请日:2011-07-12
申请人: Stefan Miller , Roman Meyer , Renate Grassl , Manfred Biebl , Holger Grallert
发明人: Stefan Miller , Roman Meyer , Renate Grassl , Manfred Biebl , Holger Grallert
IPC分类号: C12Q1/70 , G01N33/53 , C07K14/005 , C07K17/00
CPC分类号: G01N33/566 , B01D15/08 , C07K1/13 , C07K1/22 , C07K14/005 , C12N7/00 , C12N2795/00022 , C12N2795/00031 , G01N30/00 , G01N33/56911 , G01N33/92 , G01N2333/005 , G01N2400/50
摘要: The present invention relates to bacteriophage tail proteins and the derivatives and fragments thereof that are capable of binding endotoxins in the absence of bivalent positive ions, especially Ca2+ or Mg2+. Further, the present invention relates to methods for depleting endotoxins from solutions and samples using the bacteriophage tail proteins according to the present invention and to a detection method for endotoxins.
摘要翻译: 本发明涉及在没有二价阳离子,特别是Ca 2+或Mg 2+的情况下能够结合内毒素的噬菌体尾蛋白及其衍生物和片段。 此外,本发明涉及使用根据本发明的噬菌体尾蛋白从溶液和样品中消耗内毒素的方法以及内毒素的检测方法。
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公开(公告)号:US20110306068A1
公开(公告)日:2011-12-15
申请号:US13181199
申请日:2011-07-12
申请人: Stefan Miller , Roman Meyer , Renate Grassl , Manfred Biebl , Holger Grallert
发明人: Stefan Miller , Roman Meyer , Renate Grassl , Manfred Biebl , Holger Grallert
IPC分类号: G01N33/566 , C07K1/22 , C07K14/005
CPC分类号: G01N33/566 , B01D15/08 , C07K1/13 , C07K1/22 , C07K14/005 , C12N7/00 , C12N2795/00022 , C12N2795/00031 , G01N30/00 , G01N33/56911 , G01N33/92 , G01N2333/005 , G01N2400/50
摘要: The present invention relates to bacteriophage tail proteins and the derivatives and fragments thereof that are capable of binding endotoxins in the absence of bivalent positive ions, especially Ca2+ or Mg2+. Further, the present invention relates to methods for depleting endotoxins from solutions and samples using the bacteriophage tail proteins according to the present invention and to a detection method for endotoxins.
摘要翻译: 本发明涉及在没有二价阳离子,特别是Ca 2+或Mg 2+的情况下能够结合内毒素的噬菌体尾蛋白及其衍生物和片段。 此外,本发明涉及使用根据本发明的噬菌体尾蛋白从溶液和样品中消耗内毒素的方法以及内毒素的检测方法。
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公开(公告)号:US08003313B2
公开(公告)日:2011-08-23
申请号:US11814358
申请日:2006-01-23
申请人: Stefan Miller , Roman Meyer , Renate Grassl , Manfred Biebl , Holger Grallert
发明人: Stefan Miller , Roman Meyer , Renate Grassl , Manfred Biebl , Holger Grallert
IPC分类号: C12Q1/70 , G01N33/569
CPC分类号: G01N33/566 , B01D15/08 , C07K1/13 , C07K1/22 , C07K14/005 , C12N7/00 , C12N2795/00022 , C12N2795/00031 , G01N30/00 , G01N33/56911 , G01N33/92 , G01N2333/005 , G01N2400/50
摘要: The present invention relates to bacteriophage tail proteins and the derivatives and fragments thereof that are capable of binding endotoxins in the absence of bivalent positive ions, especially Ca2+ or Mg2+. Further, the present invention relates to methods for depleting endotoxins from solutions and samples using the bacteriophage tail proteins according to the present invention and to a detection method for endotoxins.
摘要翻译: 本发明涉及在没有二价阳离子,特别是Ca 2+或Mg 2+的情况下能够结合内毒素的噬菌体尾蛋白及其衍生物和片段。 此外,本发明涉及使用根据本发明的噬菌体尾蛋白从溶液和样品中消耗内毒素的方法以及内毒素的检测方法。
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公开(公告)号:US20060172281A1
公开(公告)日:2006-08-03
申请号:US10519259
申请日:2003-06-24
申请人: Michael Schutz , Roman Meyer , Holger Grallert , Stefan Miller
发明人: Michael Schutz , Roman Meyer , Holger Grallert , Stefan Miller
IPC分类号: C12Q1/70
CPC分类号: G01N33/569 , G01N33/566
摘要: The invention relates to a method for identifying endotoxins for eliminating said endotoxins from a sample, with the aid of bacteriophage tail proteins.
摘要翻译: 本发明涉及用噬菌体尾蛋白鉴定内毒素从样品中去除所述内毒素的方法。
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公开(公告)号:US20100047895A1
公开(公告)日:2010-02-25
申请号:US12510553
申请日:2009-07-28
申请人: Michael Schütz , Renate Grassl , Roman Meyer , Sibylle Frick , Ingrid Robl , Thomas Zander , Stefan Miller
发明人: Michael Schütz , Renate Grassl , Roman Meyer , Sibylle Frick , Ingrid Robl , Thomas Zander , Stefan Miller
CPC分类号: C07K14/005 , C12N15/1013 , C12N2795/10222 , Y10S436/802 , Y10T436/10
摘要: The present invention relates to a method for the selective purification of bacterial cells and/or cell components, whereby the purification is performed by means of a solid support.
摘要翻译: 本发明涉及一种选择性纯化细菌细胞和/或细胞成分的方法,由此通过固体支持物进行纯化。
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