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公开(公告)号:US20190192726A1
公开(公告)日:2019-06-27
申请号:US16287797
申请日:2019-02-27
Applicant: MicroVention, Inc.
Inventor: Gregory M. Cruise , Michael J. Constant , Edward Michael Keeley , Rob Greene , Clayton Harris
Abstract: Polymeric compositions are described comprising a biocompatible polymer including a biodegradable linkage to a visualization agent and a non-physiological solution; wherein the biocompatible polymer is soluble in the non-physiological solution and insoluble in a physiological solution. Methods of forming the solutions and polymers are disclosed as well as methods of therapeutic use.
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公开(公告)号:US20150166696A1
公开(公告)日:2015-06-18
申请号:US14536394
申请日:2014-11-07
Applicant: MicroVention, Inc.
Inventor: Steve Plotkin , Gregory M. Cruise , Edward Michael Keeley , Renee Yu , Clayton Harris
IPC: C08F22/38
CPC classification number: C08F22/385 , A61K9/0019 , A61K9/146 , A61K9/5026 , A61K31/704 , C08F290/062 , Y10T428/2982 , C08F220/10
Abstract: Polymer particle embolics and methods of making same are described. The particle embolics can be used as embolization agents.
Abstract translation: 描述聚合物颗粒栓塞及其制备方法。 颗粒栓塞可用作栓塞剂。
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公开(公告)号:US20170216484A1
公开(公告)日:2017-08-03
申请号:US15491864
申请日:2017-04-19
Applicant: MicroVention, Inc.
Inventor: Gregory M. Cruise , Michael J. Constant , Edward Michael Keeley , Rob Greene , Clayton Harris
CPC classification number: A61L24/06 , A61K49/0442 , A61K49/12 , A61L24/001 , A61L24/0015 , A61L2300/44 , A61L2400/06 , A61L2430/36 , C08L33/08 , C08L33/26
Abstract: Polymeric compositions are described comprising a biocompatible polymer including a biodegradable linkage to a visualization agent and a non-physiological pH solution; wherein the biocompatible polymer is soluble in the non-physiological pH solution and insoluble at a physiological pH. Methods of forming the solutions and polymers are disclosed as well as methods of therapeutic use.
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公开(公告)号:US20160311990A1
公开(公告)日:2016-10-27
申请号:US15199633
申请日:2016-06-30
Applicant: MicroVention, Inc.
Inventor: Gregory M. Cruise , Gloria Hincapie , Clayton Harris , Yue Wu
CPC classification number: C08J5/18 , A61K9/0024 , A61K47/32 , A61L31/048 , A61L31/148 , A61L31/16 , C08F120/56 , C08F220/56 , C08F222/1006 , C08F222/385 , C08J2333/14 , C08J2333/26 , Y10T428/21
Abstract: Biodegradable, cross-linked polymer films and methods of making the same are described. The polymer films can be used for preventing adhesions following surgery and/or delivering therapeutic agents.
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公开(公告)号:US20140107251A1
公开(公告)日:2014-04-17
申请号:US14054515
申请日:2013-10-15
Applicant: MicroVention, Inc.
Inventor: Gregory M. Cruise , Michael J. Constant , Edward Michael Keeley , Rob Greene , Clayton Harris
IPC: A61L24/06
CPC classification number: A61L24/06 , A61K49/0442 , A61K49/12 , A61L24/001 , A61L24/0015 , A61L2300/44 , A61L2400/06 , A61L2430/36 , C08L33/08 , C08L33/26
Abstract: Polymeric compositions are described comprising a biocompatible polymer including a biodegradable linkage to a visualization agent and a non-physiological pH solution; wherein the biocompatible polymer is soluble in the non-physiological pH solution and insoluble at a physiological pH. Methods of forming the solutions and polymers are disclosed as well as methods of therapeutic use.
Abstract translation: 描述了包含生物相容性聚合物的聚合物组合物,其包括与可视化试剂和非生理pH溶液的生物可降解连接; 其中所述生物相容性聚合物可溶于非生理pH溶液中,并且在生理pH下不溶。 公开了形成溶液和聚合物的方法以及治疗用途的方法。
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公开(公告)号:US20240108781A1
公开(公告)日:2024-04-04
申请号:US18482688
申请日:2023-10-06
Applicant: MicroVention, Inc.
Inventor: Gregory M. Cruise , Michael J. Constant , Edward Michael Keeley , Rob Greene , Clayton Harris
CPC classification number: A61L24/06 , A61K49/0442 , A61K49/12 , A61L24/001 , A61L24/0015 , A61L2300/44 , A61L2400/06 , A61L2430/36
Abstract: Polymeric compositions are described comprising a biocompatible polymer including a biodegradable linkage to a visualization agent and a non-physiological solution; wherein the biocompatible polymer is soluble in the non-physiological solution and insoluble in a physiological solution. Methods of forming the solutions and polymers are disclosed as well as methods of therapeutic use.
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公开(公告)号:US10258716B2
公开(公告)日:2019-04-16
申请号:US15491864
申请日:2017-04-19
Applicant: MicroVention, Inc.
Inventor: Gregory M. Cruise , Michael J. Constant , Edward Michael Keeley , Rob Greene , Clayton Harris
Abstract: Polymeric compositions are described comprising a biocompatible polymer including a biodegradable linkage to a visualization agent and a non-physiological pH solution; wherein the biocompatible polymer is soluble in the non-physiological pH solution and insoluble at a physiological pH. Methods of forming the solutions and polymers are disclosed as well as methods of therapeutic use.
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公开(公告)号:US20160243273A1
公开(公告)日:2016-08-25
申请号:US14736145
申请日:2015-06-10
Applicant: MicroVention, Inc.
Inventor: Gregory M. Cruise , Michael J. Constant , Edward Michael Keeley , Rob Greene , Clayton Harris
CPC classification number: A61L24/06 , A61K49/0442 , A61K49/12 , A61L24/001 , A61L24/0015 , A61L2300/44 , A61L2400/06 , A61L2430/36 , C08L33/08 , C08L33/26
Abstract: Polymeric compositions are described comprising a biocompatible polymer including a biodegradable linkage to a visualization agent and a non-physiological pH solution; wherein the biocompatible polymer is soluble in the non-physiological pH solution and insoluble at a physiological pH. Methods of forming the solutions and polymers are disclosed as well as methods of therapeutic use.
Abstract translation: 描述了包含生物相容性聚合物的聚合物组合物,其包括与可视化试剂和非生理pH溶液的生物可降解连接; 其中所述生物相容性聚合物可溶于非生理pH溶液中,并且在生理pH下不溶。 公开了形成溶液和聚合物的方法以及治疗用途的方法。
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公开(公告)号:US09408916B2
公开(公告)日:2016-08-09
申请号:US14491813
申请日:2014-09-19
Applicant: MicroVention, Inc.
Inventor: Gregory M. Cruise , Gloria Hincapie , Clayton Harris , Yue Wu
IPC: C08F120/56 , A61K47/32 , A61L31/14 , A61L31/16 , A61K9/00 , C08F220/56 , C08F222/10 , C08F222/38
CPC classification number: C08J5/18 , A61K9/0024 , A61K47/32 , A61L31/048 , A61L31/148 , A61L31/16 , C08F120/56 , C08F220/56 , C08F222/1006 , C08F222/385 , C08J2333/14 , C08J2333/26 , Y10T428/21
Abstract: Biodegradable, cross-linked polymer films and methods of making the same are described. The polymer films can be used for preventing adhesions following surgery and/or delivering therapeutic agents.
Abstract translation: 描述了可生物降解的交联聚合物膜及其制备方法。 聚合物膜可以用于防止手术后和/或递送治疗剂的粘连。
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公开(公告)号:US20150079395A1
公开(公告)日:2015-03-19
申请号:US14491776
申请日:2014-09-19
Applicant: MicroVention, Inc.
Inventor: Gregory M. Cruise , Gloria Hincapie , Clayton Harris
IPC: C08F220/56
CPC classification number: C08F220/38 , A61K9/0029 , A61K9/1635 , A61L24/001 , A61L24/06 , A61L31/048 , A61L2430/36 , C08F220/56 , C08F222/1006 , C08F222/385 , C08F2220/382 , C08F2222/408 , Y10T428/2982 , C08L33/08
Abstract: Biodegradable, cross-linked polymer particle embolics and methods of making the same are described. The particle embolics can be used as embolization agents.
Abstract translation: 描述了可生物降解的交联聚合物颗粒栓塞及其制备方法。 颗粒栓塞可用作栓塞剂。
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