METHODS FOR PURIFYING 2-ARYL-3,3-BIS(HYDROXYARYL)PHTHALIMIDINES
    8.
    发明申请
    METHODS FOR PURIFYING 2-ARYL-3,3-BIS(HYDROXYARYL)PHTHALIMIDINES 有权
    纯化2-芳基-3,3-二(羟基)苯基二胺的方法

    公开(公告)号:US20170029562A1

    公开(公告)日:2017-02-02

    申请号:US15302510

    申请日:2015-04-22

    CPC classification number: C08G64/12 C07D209/46

    Abstract: Methods for synthesizing and purifying 2-aryl-3,3-bis(4-hydroxyaryl)phthalimidine compounds are provided. The method includes heating a reaction mixture including a phenolphthalein, a primary aryl amine, and an acid catalyst to form a phthalimidine; precipitating the phthalimidine from the reaction mixture to provide a crude phthalimidine; providing a solution including the crude phthalimidine, an additive, and at least one solvent; contacting the solution with one or more purification agents to provide a treated solution; precipitating and recovering a phthalimidine adduct from the treated solution; and recovering a purified phthalimidine compound from the adduct.

    Abstract translation: 提供2-芳基-3,3-双(4-羟基芳基)苯并嘧啶化合物的合成和纯化方法。 该方法包括加热包括酚酞,伯芳基胺和酸催化剂的反应混合物以形成苯二酰亚胺; 从反应混合物中沉淀苯二酰亚胺,得到粗的苯二酰亚胺; 提供包括粗的苯二酰亚胺,添加剂和至少一种溶剂的溶液; 使溶液与一种或多种纯化剂接触以提供处理的溶液; 从处理过的溶液中沉淀并回收苯二酰亚胺加合物; 并从加合物中回收纯化的苯虫胺化合物。

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