公开(公告)号：US11820863B2

公开(公告)日：2023-11-21

申请号：US16303769

申请日：2017-05-26

Applicant: SPHERE FLUIDICS LIMITED

Inventor： Xin Li ,  Clive A. Smith ,  Alexandra Clay ,  Frank F. Craig

IPC: C08G65/332 ,  C08G65/00 ,  C08G65/333 ,  C08G65/334 ,  C12Q1/6806 ,  C09K23/00

CPC classification number: C08G65/3322 ,  C08G65/007 ,  C08G65/3348 ,  C08G65/33344 ,  C08G65/33396 ,  C09K23/007 ,  C12Q1/6806

Abstract: The present invention provides a surfactant having a formula selected from the group consisting of: B—((X)x—(CH2)a-A)n(VI), (A-(CH2)a—(X)x—B—(X)x—(CH2)a-A)n (IV), (A-(CH2)a—(X)x—B)n (V), and (B)n—(X)x—(CH2)a-A (VII), wherein A is a perfluoropolyether; a is a positive integer; X is either a covalent bond or a linking group; x is a positive integer; B is a polyalkylene oxide unit; n is a positive integer greater than 1 and, in compounds comprising more than one A, B, X, a and x, each may be the same or different. The present invention also relates to methods of making such surfactants, uses of such surfactants and emulsions comprising such surfactants.

公开(公告)号：US20180250677A1

公开(公告)日：2018-09-06

申请号：US15754754

申请日：2016-09-06

Applicant: SPHERE FLUIDICS LIMITED

Inventor： Xin LI ,  Xin Liu ,  Alexandra Clay

IPC: B01L3/00 ,  B01L3/02

CPC classification number: B01L3/502776 ,  B01L3/0241 ,  B01L3/502715 ,  B01L3/502784 ,  B01L2200/0647 ,  B01L2200/0673 ,  B01L2300/0816 ,  B01L2300/0867 ,  B01L2300/161 ,  B01L2400/0463 ,  B01L2400/0487

Abstract: A microfluidic structure for spacing out and aligning entities in an aqueous suspension is provided. The structure comprises: a channel for guiding entities in an aqueous suspension; a first comb of first inlets arranged on a first side of the channel for introducing a spacing medium into the channel; and a second comb of second inlets arranged on a second side of the channel for introducing the spacing medium into the channel; wherein the first side is opposite the second side, and wherein one of the first inlets has a corresponding, respective one of the second inlets at a substantially similar longitudinal position along the channel.

公开(公告)号：US10828640B2

公开(公告)日：2020-11-10

申请号：US15754754

申请日：2016-09-06

Applicant: SPHERE FLUIDICS LIMITED

Inventor： Xin Li ,  Xin Liu ,  Alexandra Clay

IPC: B01L3/00 ,  B01L3/02

Abstract: A microfluidic structure for spacing out and aligning entities in an aqueous suspension is provided. The structure comprises: a channel for guiding entities in an aqueous suspension; a first comb of first inlets arranged on a first side of the channel for introducing a spacing medium into the channel; and a second comb of second inlets arranged on a second side of the channel for introducing the spacing medium into the channel; wherein the first side is opposite the second side, and wherein one of the first inlets has a corresponding, respective one of the second inlets at a substantially similar longitudinal position along the channel.

公开(公告)号：US20200017635A1

公开(公告)日：2020-01-16

申请号：US16303769

申请日：2017-05-26

Applicant: SPHERE FLUIDICS LIMITED

Inventor： Xin LI ,  Olive A Smith ,  Alexandra Clay ,  Frank F Craig

IPC: C08G65/332 ,  C08G65/00 ,  C08G65/333 ,  C08G65/334 ,  C12Q1/6806 ,  B01F17/00

Abstract: The present invention provides a surfactant having a formula selected from the group consisting of: B—((X)x—(CH2)a-Mn(VI), (A-(CH2)—(X)x—B—(X)x—(CH2)a-A)n (IV), (A-(CH2)a—(X)x—B)n (V), and (B)n—(X)x—(CH2)a—A (VII), wherein A is a perfluoropolyether; a is a positive integer; X is either a covalent bond or a linking group; x is a positive integer; B is a polyalkylene oxide unit; n is a positive integer greater than 1 and, in compounds comprising more than one A, B, X, a and x, each may be the same or different. The present invention also relates to methods of making such surfactants, uses of such surfactants and emulsions comprising such surfactants.

公开(公告)号：US12110441B2

公开(公告)日：2024-10-08

申请号：US16768121

申请日：2018-11-29

Applicant: SPHERE FLUIDICS LIMITED

Inventor： Xin Li ,  Clive A. Smith ,  Alexandra Clay ,  Colin Pilkington

IPC: C09K23/18 ,  B01D11/04 ,  B01D17/04 ,  B01D17/12 ,  B01L3/00 ,  C08G65/00 ,  C09K23/00 ,  C09K23/16

CPC classification number: C09K23/18 ,  B01D11/0492 ,  B01D11/0496 ,  B01D17/045 ,  B01D17/12 ,  B01L3/5021 ,  C08G65/007 ,  C09K23/007 ,  C09K23/16

Abstract: A surfactant of formula (I):

A-(L1)a-(C2)b-(L2)c-X  (I)

wherein
A is a perfluoropolyether;
L1 is CONR', wherein R′ is selected from H and C1-6 alkyl;
a is 0 or 1;
b is 0 or an integer between 1 and 10;
L2 is a linking group;
c is 0 or 1; and
X is a charged group.